Primary Site >> Colorectal Cancer

Gene >> SPINK1

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Ref: The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
PMID: 2459273
 Ref: [Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data].
PMID: 2717042
 Ref: Rearrangement, amplification and overexpression of c-Ha Ras gene in premalignant lesion of Turcot's syndrome.
PMID: 1703248
Ref: Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
PMID: 2224769
Ref: Expression of pancreatic secretory trypsin inhibitor (PSTI) in colorectal cancer.
PMID: 2257226
 Ref: Folate-binding protein is a marker for ovarian cancer.
PMID: 1717147
Ref: Evaluation of TATI and other markers in solid tumors.
PMID: 1780686
Ref: Tumor-associated trypsin inhibitor (TATI) in patients with colorectal carcinoma. A critical comparison with CEA.
PMID: 1780689
Ref: Tumor-associated trypsin inhibitor, TATI, in gastrointestinal cancer and related benign diseases.
PMID: 1780697
Ref: Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
PMID: 1995487
Ref: Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
PMID: 2009530
 Ref: Sequence of the complete cDNA and the 5' structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase.
PMID: 1353958
 Ref: Tumour markers and screening for gastrointestinal cancer: a follow up study in Finland.
PMID: 8790487
 Ref: Tumour-associated trypsin inhibitor (TATI) in patients with colorectal cancer: a comparison with CEA, CA 50 and CA 242.
PMID: 7667604
 Ref: Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
PMID: 12973686
Ref: Polymorphisms of SPINK1 N34S and CFTR in patients with sporadic and familial pancreatic cancer.
PMID: 14688470
 Ref: Tumour-associated trypsin inhibitor, carcinoembryonic antigen and acute-phase reactant proteins CRP and alpha1-antitrypsin in patients with gastrointestinal malignancies.
PMID: 14675563
Ref: [Genetic polymorphism in cytochrome P450 2E1, salted food and colorectal cancer susceptibility: a case-control study].
PMID: 15182482
 Ref: Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
PMID: 18317448
 Ref: High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
PMID: 19384300
 Ref: CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis.
PMID: 20556843
Ref: Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
PMID: 20849596
 Ref: Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
PMID: 21864386
 Ref: Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
PMID: 22508321
 Ref: Concomitant tumor expression of EGFR and TATI/SPINK1 associates with better prognosis in colorectal cancer.
PMID: 24204699
 Ref: SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
PMID: 25804623
Ref: Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
PMID: 26037168
Ref: SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
PMID: 26258891
Ref: A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer.
PMID: 26782431
 Ref: Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.
PMID: 26663388
Ref: Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
PMID: 27107100
 Ref: MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.
PMID: 29193645
Ref: Postoperative CEA is a better prognostic marker than CA19-9, hCGbeta or TATI after resection of colorectal liver metastases.
PMID: 29378497