Primary Site >> Stomach Cancer

Gene >> SPHK1

Journal: Biochim Biophys Acta. 2002 Dec 30;1585(2-3):193-201.
Title: Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.
Author: Maceyka, Michael|Payne, Shawn G|Milstien, Sheldon|Spiegel, Sarah
PMID: 12531554
Journal: Mol Cancer Ther. 2007 Aug;6(8):2346-59.
Title: 213Bi-induced death of HSC45-M2 gastric cancer cells is characterized by G2 arrest and up-regulation of genes known to prevent apoptosis but induce necrosis and mitotic catastrophe.
Author: Seidl, Christof|Port, Matthias|Gilbertz, Klaus-Peter|Morgenstern, Alfred|Bruchertseifer, Frank|Schwaiger, Markus|Roper, Barbara|Senekowitsch-Schmidtke, Reingard|Abend, Michael
PMID: 17699730
Journal: Cancer Res. 2008 Aug 15;68(16):6569-77.
Title: Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.
Author: Shida, Dai|Fang, Xianjun|Kordula, Tomasz|Takabe, Kazuaki|Lepine, Sandrine|Alvarez, Sergio E|Milstien, Sheldon|Spiegel, Sarah
PMID: 18701480
Journal: Clin Cancer Res. 2009 Feb 15;15(4):1393-9.
Title: Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients.
Author: Li, Wen|Yu, Chun-Ping|Xia, Jin-tang|Zhang, Ling|Weng, Gui-Xiang|Zheng, Hai-qing|Kong, Qing-li|Hu, Li-juan|Zeng, Mu-Sheng|Zeng, Yi-xin|Li, Mengfeng|Li, Jun|Song, Li-Bing
PMID: 19228740
Journal: FEBS Lett. 2010 Sep 24;584(18):4077-82.
Title: Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.
Author: Ramachandran, Subramaniam|Shida, Dai|Nagahashi, Masayuki|Fang, Xianjun|Milstien, Sheldon|Takabe, Kazuaki|Spiegel, Sarah
PMID: 20804754
Journal: Anticancer Drugs. 2011 Mar;22(3):245-52.
Title: Sphingosine kinase 1 is a relevant molecular target in gastric cancer.
Author: Fuereder, Thorsten|Hoeflmayer, Doris|Jaeger-Lansky, Agnes|Rasin-Streden, Doris|Strommer, Sabine|Fisker, Niels|Hansen, Bo J|Crevenna, Richard|Wacheck, Volker
PMID: 21360847
Journal: Zhonghua Yi Xue Za Zhi. 2011 Oct 25;91(39):2765-8.
Title: [Relationship between sphingosine kinase 1 expression and tumor invasion, metastasis and prognosis in gastric cancer].
Author: Zhuge, Yong-hua|Tao, Hou-quan|Wang, Yuan-yu
PMID: 22322056
Journal: J Pathol. 2012 Aug;227(4):470-80.
Title: miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1.
Author: Xia, Jintang|Wu, Zhiqiang|Yu, Chunping|He, Weiling|Zheng, Haiqing|He, Yulong|Jian, Weihua|Chen, Lianzhou|Zhang, Luanjing|Li, Wen
PMID: 22450659
Journal: Zhonghua Zhong Liu Za Zhi. 2012 Feb;34(2):96-9.
Title: [Antitumor effect of sphingosine kinase 1 inhibitor in combination with chemotherapy on SGC7901 gastric cancer cells in vitro].
Author: Yin, Guo-Jian|Lan, Kang-Hua|Hu, Chuang-Ying|Lu, Qin|Tang, Wen|Wang, Shao-Feng
PMID: 22780925
Journal: Zhonghua Zhong Liu Za Zhi. 2013 Jul;35(7):497-500.
Title: [miR-124 suppresses cell proliferation and invasion in gastric carcinoma and its mechanism].
Author: Xie, Li-ming|He, Rong-fang|Zhang, Zhi-wei|Tang, Yun-yun|Luo, Zhao-yang
PMID: 24257299
Journal: Oncol Rep. 2014 Oct;32(4):1369-73.
Title: SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling.
Author: Xiong, Huaping|Wang, Jicheng|Guan, Hongyu|Wu, Jueheng|Xu, Ru|Wang, Min|Rong, Xia|Huang, Ke|Huang, Jieting|Liao, Qiao|Fu, Yongshui|Yuan, Jie
PMID: 25109605
Journal: Asian Pac J Cancer Prev. 2014;15(23):10381-5.
Title: A sphingosine kinase-1 inhibitor, SKI-II, induces growth inhibition and apoptosis in human gastric cancer cells.
Author: Li, Pei-Hua|Wu, Jin-Xia|Zheng, Jun-Nian|Pei, Dong-Sheng
PMID: 25556479
Journal: BMC Cancer. 2015 Oct 22;15:762.
Title: Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer.
Author: Matula, Kasia|Collie-Duguid, Elaina|Murray, Graeme|Parikh, Khyati|Grabsch, Heike|Tan, Patrick|Lalwani, Salina|Garau, Roberta|Ong, Yuhan|Bain, Gillian|Smith, Asa-Dahle|Urquhart, Gordon|Bielawski, Jacek|Finnegan, Michael|Petty, Russell
PMID: 26493335
Journal: Oncotarget. 2016 Aug 2;7(31):49322-49333.
Title: Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients.
Author: Szasz, A Marcell|Lanczky, Andras|Nagy, Adam|Forster, Susann|Hark, Kim|Green, Jeffrey E|Boussioutas, Alex|Busuttil, Rita|Szabo, Andras|Gyorffy, Balazs
PMID: 27384994
Journal: Clin Lab. 2017 Sep 1;63(9):1347-1356.
Title: Functional Genetic Variants in SPHK1 Affect Susceptibility to Gastric Cancer in a Chinese Population.
Author: Huan, Xiangkun|He, Yu|Huang, Chi|Wang, Younan|Zhu, Yi|Xu, Zekuan|Yang, Li|Cao, Huaxiang
PMID: 28879695
Journal: IUBMB Life. 2018 Nov;70(11):1164-1176.
Title: Up-regulation and tumor-promoting role of SPHK1 were attenuated by miR-330-3p in gastric cancer.
Author: Wang, Zhihua|Qu, Huajun|Gong, Wenjing|Liu, Aina
PMID: 30281914