Primary Site >> Colorectal Cancer
Gene >> SPHK1
| 1. | |||||||||||
| Journal: | Prostaglandins Other Lipid Mediat. 2007 Nov;84(3-4):154-62. | ||||||||||
| Title: | A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC). | ||||||||||
| Author: | Lee, Yong-Moon|Venkataraman, Krishnan|Hwang, Sun-Il|Han, David K|Hla, Timothy | ||||||||||
| PMID: | 17991617 | ||||||||||
| 2. | |||||||||||
| Journal: | Cell Cycle. 2007 Mar 1;6(5):522-7. | ||||||||||
| Title: | Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again. | ||||||||||
| Author: | Oskouian, Babak|Saba, Julie | ||||||||||
| PMID: | 17361098 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2008 Aug 15;68(16):6569-77. | ||||||||||
| Title: | Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. | ||||||||||
| Author: | Shida, Dai|Fang, Xianjun|Kordula, Tomasz|Takabe, Kazuaki|Lepine, Sandrine|Alvarez, Sergio E|Milstien, Sheldon|Spiegel, Sarah | ||||||||||
| PMID: | 18701480 | ||||||||||
| 4. | |||||||||||
| Journal: | FASEB J. 2009 Feb;23(2):405-14. | ||||||||||
| Title: | Role for sphingosine kinase 1 in colon carcinogenesis. | ||||||||||
| Author: | Kawamori, Toshihiko|Kaneshiro, Tatsuya|Okumura, Masae|Maalouf, Samer|Uflacker, Andre|Bielawski, Jacek|Hannun, Yusuf A|Obeid, Lina M | ||||||||||
| PMID: | 18824518 | ||||||||||
| 5. | |||||||||||
| Journal: | Glycoconj J. 2009 Jul;26(5):547-58. | ||||||||||
| Title: | VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo. | ||||||||||
| Author: | Kolmakova, Antonina|Rajesh, Mohanraj|Zang, David|Pili, Roberto|Chatterjee, Subroto | ||||||||||
| PMID: | 19219548 | ||||||||||
| 6. | |||||||||||
| Journal: | J Biol Chem. 2009 Apr 17;284(16):10422-32. | ||||||||||
| Title: | Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. | ||||||||||
| Author: | Nemoto, Satoshi|Nakamura, Mitsuhiro|Osawa, Yosuke|Kono, Saki|Itoh, Yoshinori|Okano, Yukio|Murate, Takashi|Hara, Akira|Ueda, Hiroshi|Nozawa, Yoshinori|Banno, Yoshiko | ||||||||||
| PMID: | 19240026 | ||||||||||
| 7. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2011 Mar;33(3):178-82. | ||||||||||
| Title: | [Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms]. | ||||||||||
| Author: | Liu, Shi-quan|Qin, Meng-bin|Huang, Jie-an|Zhong, Yue-yuan|Tang, Guo-du|Jiang, Hai-xing | ||||||||||
| PMID: | 21575515 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncol Res. 2011;19(12):573-82. | ||||||||||
| Title: | Inhibition of SPHK1 suppresses phorbol 12-myristate 13-acetate-induced metastatic phenotype in colorectal cancer HT-29 cells. | ||||||||||
| Author: | Qin, Meng-Bin|Huang, Jie-An|Liu, Shi-Quan|Tang, Guo-Du|Jiang, Hai-Xing | ||||||||||
| PMID: | 22812190 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Colorectal Dis. 2012 Dec;27(12):1569-78. | ||||||||||
| Title: | Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways. | ||||||||||
| Author: | Liu, Shi-Quan|Huang, Jie-An|Qin, Meng-Bin|Su, Ying-Jie|Lai, Ming-Yu|Jiang, Hai-Xing|Tang, Guo-Du | ||||||||||
| PMID: | 22684547 | ||||||||||
| 10. | |||||||||||
| Journal: | Zhonghua Nei Ke Za Zhi. 2012 Mar;51(3):220-4. | ||||||||||
| Title: | [The expression and clinical significance of SphK1 and nuclear factor-kappaB p65 in human colon carcinoma]. | ||||||||||
| Author: | Su, Ying-jie|Huang, Jie-an|Liu, Shi-quan|Huang, Juan-xiu|Zhong, Yue-yuan|Tang, Guo-du|Jiang, Hai-xing | ||||||||||
| PMID: | 22781898 | ||||||||||
| 11. | |||||||||||
| Journal: | Exp Cell Res. 2012 Jan 1;318(1):43-52. | ||||||||||
| Title: | Sensitization of human colon cancer cells to sodium butyrate-induced apoptosis by modulation of sphingosine kinase 2 and protein kinase D. | ||||||||||
| Author: | Xiao, Min|Liu, Yungang|Zou, Fei | ||||||||||
| PMID: | 22024383 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Jan 1;19(1):138-47. | ||||||||||
| Title: | Sphingosine kinase 1 overexpression contributes to cetuximab resistance in human colorectal cancer models. | ||||||||||
| Author: | Rosa, Roberta|Marciano, Roberta|Malapelle, Umberto|Formisano, Luigi|Nappi, Lucia|D'Amato, Claudia|D'Amato, Valentina|Damiano, Vincenzo|Marfe, Gabriella|Del Vecchio, Silvana|Zannetti, Antonella|Greco, Adelaide|De Stefano, Alfonso|Carlomagno, Chiara|Venezia | ||||||||||
| PMID: | 23166225 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Oncol. 2013 Feb;42(2):617-26. | ||||||||||
| Title: | Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules. | ||||||||||
| Author: | Liu, Shi-Quan|Su, Ying-Jie|Qin, Meng-Bin|Mao, Ye-Bo|Huang, Jie-An|Tang, Guo-Du | ||||||||||
| PMID: | 23232649 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Cell. 2013 Jan 14;23(1):107-20. | ||||||||||
| Title: | Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. | ||||||||||
| Author: | Liang, Jie|Nagahashi, Masayuki|Kim, Eugene Y|Harikumar, Kuzhuvelil B|Yamada, Akimitsu|Huang, Wei-Ching|Hait, Nitai C|Allegood, Jeremy C|Price, Megan M|Avni, Dorit|Takabe, Kazuaki|Kordula, Tomasz|Milstien, Sheldon|Spiegel, Sarah | ||||||||||
| PMID: | 23273921 | ||||||||||
| 15. | |||||||||||
| Journal: | Anticancer Drugs. 2013 Jun;24(5):473-83. | ||||||||||
| Title: | Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells. | ||||||||||
| Author: | Kawahara, Satomi|Otsuji, Yoko|Nakamura, Mitsuhiro|Murakami, Masashi|Murate, Takashi|Matsunaga, Toshiyuki|Kanoh, Hiroyuki|Seishima, Mariko|Banno, Yoshiko|Hara, Akira | ||||||||||
| PMID: | 23426175 | ||||||||||
| 16. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2013 May;35(5):331-6. | ||||||||||
| Title: | [Sphingosine kinase 1 enhances the proliferation and invasion of human colon cancer LoVo cells through up-regulating FAK pathway and the expression of ICAM-1 and VCAM-1]. | ||||||||||
| Author: | Liu, Shi-quan|Su, Ying-jie|Huang, Jie-an|Qin, Meng-bin|Tang, Guo-du | ||||||||||
| PMID: | 24054007 | ||||||||||
| 17. | |||||||||||
| Journal: | Eur J Pharmacol. 2013 Oct 15;718(1-3):145-53. | ||||||||||
| Title: | Targeting sphingosine kinase 1 (SphK1) and apoptosis by colon-specific delivery formula of resveratrol in treatment of experimental ulcerative colitis in rats. | ||||||||||
| Author: | Abdin, Amany A | ||||||||||
| PMID: | 24055189 | ||||||||||
| 18. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Aug 14;20(30):10279-87. | ||||||||||
| Title: | STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. | ||||||||||
| Author: | Nguyen, Andrew V|Wu, Yuan-Yuan|Lin, Elaine Y | ||||||||||
| PMID: | 25132744 | ||||||||||
| 19. | |||||||||||
| Journal: | Clin Exp Gastroenterol. 2014 Jun 30;7:205-14. | ||||||||||
| Title: | S1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancer. | ||||||||||
| Author: | Degagne, Emilie|Saba, Julie D | ||||||||||
| PMID: | 25061328 | ||||||||||
| 20. | |||||||||||
| Journal: | Adv Biol Regul. 2014 Jan;54:112-20. | ||||||||||
| Title: | Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. | ||||||||||
| Author: | Nagahashi, Masayuki|Hait, Nitai C|Maceyka, Michael|Avni, Dorit|Takabe, Kazuaki|Milstien, Sheldon|Spiegel, Sarah | ||||||||||
| PMID: | 24210073 | ||||||||||
| 21. | |||||||||||
| Journal: | Clin Transl Gastroenterol. 2014 Feb 27;5:e51. | ||||||||||
| Title: | Sphingosine kinase 1 promotes malignant progression in colon cancer and independently predicts survival of patients with colon cancer by competing risk approach in South asian population. | ||||||||||
| Author: | Tan, Sheryl S L|Khin, Lay W|Wong, Lingkai|Yan, Benedict|Ong, Chee W|Datta, Arpita|Salto-Tellez, Manuel|Lam, Yulin|Yap, Celestial T | ||||||||||
| PMID: | 24572701 | ||||||||||
| 22. | |||||||||||
| Journal: | J Cell Biochem. 2015 Oct;116(10):2227-38. | ||||||||||
| Title: | Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor. | ||||||||||
| Author: | Mizutani, Naoki|Omori, Yukari|Tanaka, Koji|Ito, Hiromi|Takagi, Akira|Kojima, Tetsuhito|Nakatochi, Masahiro|Ogiso, Hideo|Kawamoto, Yoshiyuki|Nakamura, Mitsuhiro|Suzuki, Motoshi|Kyogashima, Mamoru|Tamiya-Koizumi, Keiko|Nozawa, Yoshinori|Murate, Takashi | ||||||||||
| PMID: | 25808826 | ||||||||||
| 23. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2015 Aug 7;463(4):954-60. | ||||||||||
| Title: | MicroRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells. | ||||||||||
| Author: | Chen, Min-Bin|Yang, Lan|Lu, Pei-Hua|Fu, Xing-Li|Zhang, Yan|Zhu, Ya-Qun|Tian, Ye | ||||||||||
| PMID: | 26071354 | ||||||||||
| 24. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2015 Sep 4;34:94. | ||||||||||
| Title: | Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo. | ||||||||||
| Author: | Xun, Cai|Chen, Min-Bin|Qi, Li|Tie-Ning, Zhang|Peng, Xue|Ning, Li|Zhi-Xiao, Chen|Li-Wei, Wang | ||||||||||
| PMID: | 26337959 | ||||||||||
| 25. | |||||||||||
| Journal: | Tumour Biol. 2016 May;37(5):6831-6. | ||||||||||
| Title: | SphK1 promotes tumor cell migration and invasion in colorectal cancer. | ||||||||||
| Author: | Long, Jianting|Xie, Ying|Yin, Junmei|Lu, Wei|Fang, Shi | ||||||||||
| PMID: | 26662312 | ||||||||||
| 26. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Feb 12;470(3):728-734. | ||||||||||
| Title: | Targeting colorectal cancer cells by a novel sphingosine kinase 1 inhibitor PF-543. | ||||||||||
| Author: | Ju, TongFa|Gao, DaQuan|Fang, Zheng-Yu | ||||||||||
| PMID: | 26775841 | ||||||||||
| 27. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Feb 28;22(8):2503-11. | ||||||||||
| Title: | Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer. | ||||||||||
| Author: | Shida, Dai|Inoue, Satoru|Yoshida, Yuki|Kodaka, Atsushi|Tsuji, Tsutomu|Tsuiji, Makoto | ||||||||||
| PMID: | 26937138 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncotarget. 2016 May 3;7(18):26780-92. | ||||||||||
| Title: | Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer. | ||||||||||
| Author: | Bao, Yonghua|Li, Kai|Guo, Yongchen|Wang, Qian|Li, Zexin|Yang, Yiqiong|Chen, Zhiguo|Wang, Jianguo|Zhao, Weixing|Zhang, Huijuan|Chen, Jiwang|Dong, Huali|Shen, Kui|Diamond, Alan M|Yang, Wancai | ||||||||||
| PMID: | 27050145 | ||||||||||
| 29. | |||||||||||
| Journal: | Bioorg Med Chem. 2016 Jul 15;24(14):3218-30. | ||||||||||
| Title: | Development of hydroxy-based sphingosine kinase inhibitors and anti-inflammation in dextran sodium sulfate induced colitis in mice. | ||||||||||
| Author: | Xi, Meiyang|Ge, Jun|Wang, Xiaojian|Sun, Chenbin|Liu, Tianqi|Fang, Liang|Xiao, Qiong|Yin, Dali | ||||||||||
| PMID: | 27255176 | ||||||||||
| 30. | |||||||||||
| Journal: | Am J Cancer Res. 2016 Sep 1;6(9):1976-1985. eCollection 2016. | ||||||||||
| Title: | miR-659-3p is involved in the regulation of the chemotherapy response of colorectal cancer via modulating the expression of SPHK1. | ||||||||||
| Author: | Li, Shuyuan|Fang, Ying|Qin, Hai|Fu, Wenzheng|Zhang, Xipeng | ||||||||||
| PMID: | 27725903 | ||||||||||
| 31. | |||||||||||
| Journal: | PLoS One. 2017 Jan 12;12(1):e0169585. | ||||||||||
| Title: | AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms. | ||||||||||
| Author: | Zhang, Shihu|Deng, Zhengming|Yao, Chen|Huang, Ping|Zhang, Yi|Cao, Shibing|Li, Xiangcheng | ||||||||||
| PMID: | 28081222 | ||||||||||
| 32. | |||||||||||
| Journal: | Carcinogenesis. 2017 Dec 7;38(12):1218-1227. | ||||||||||
| Title: | Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis. | ||||||||||
| Author: | Furuya, Hideki|Tamashiro, Paulette M|Shimizu, Yoshiko|Iino, Kayoko|Peres, Rafael|Chen, Runpu|Sun, Yijun|Hannun, Yusuf A|Obeid, Lina M|Kawamori, Toshihiko | ||||||||||
| PMID: | 29028945 | ||||||||||
| 33. | |||||||||||
| Journal: | Int J Mol Sci. 2017 Oct 8;18(10). pii: ijms18102109. | ||||||||||
| Title: | Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer. | ||||||||||
| Author: | Bao, Yonghua|Guo, Yongchen|Zhang, Chenglan|Fan, Fenghua|Yang, Wancai | ||||||||||
| PMID: | 28991193 | ||||||||||
| 34. | |||||||||||
| Journal: | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 May;33(5):623-629. | ||||||||||
| Title: | [Down-regulation of sphingosine kinase 1 (SphK1) enhances the chemosensitivity to cisplatin in human colon cancer RKO cells]. | ||||||||||
| Author: | Qin, Lin|Liu, Shiquan|Qin, Mengbin|Wu, Wenhong|Qin, Nan|Fu, Zhenhua|Xu, Chunyan|Huang, Jie'an|Lai, Mingyu | ||||||||||
| PMID: | 28502300 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):39605-39617. | ||||||||||
| Title: | Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRalpha by K48/K63-linked polyubiquitination. | ||||||||||
| Author: | Shi, Wen-Na|Cui, Shu-Xiang|Song, Zhi-Yu|Wang, Shu-Qing|Sun, Shi-Yue|Yu, Xin-Feng|Li, Ye|Zhang, Yu-Hang|Gao, Zu-Hua|Qu, Xian-Jun | ||||||||||
| PMID: | 28465486 | ||||||||||
| 36. | |||||||||||
| Journal: | Int J Mol Med. 2017 May;39(5):1277-1284. | ||||||||||
| Title: | SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells. | ||||||||||
| Author: | Xu, Chun-Yan|Liu, Shi-Quan|Qin, Meng-Bin|Zhuge, Chun-Feng|Qin, Lin|Qin, Nan|Lai, Ming-Yu|Huang, Jie-An | ||||||||||
| PMID: | 28405684 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncotarget. 2018 Feb 26;9(21):15635-15649. | ||||||||||
| Title: | Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice. | ||||||||||
| Author: | Chen, Jinbiao|Qi, Yanfei|Zhao, Yang|Kaczorowski, Dominik|Couttas, Timothy A|Coleman, Paul R|Don, Anthony S|Bertolino, Patrick|Gamble, Jennifer R|Vadas, Mathew A|Xia, Pu|McCaughan, Geoffrey W | ||||||||||
| PMID: | 29643998 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncol Lett. 2018 Jun;15(6):9719-9724. | ||||||||||
| Title: | Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells. | ||||||||||
| Author: | Xu, Chunyan|Zhang, Wenlu|Liu, Shiquan|Wu, Wenhong|Qin, Mengbin|Huang, Jiean | ||||||||||
| PMID: | 29928348 | ||||||||||
| 39. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Aug 28. pii: 1541-7786.MCR-18-0199. | ||||||||||
| Title: | De Novo Fatty Acid Synthesis Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer. | ||||||||||
| Author: | Jafari, Naser|Drury, James|Morris, Andrew J|Onono, Fredrick O|Stevens, Payton D|Gao, Tianyan|Liu, Jinpeng|Wang, Chi|Lee, Eun Y|Weiss, Heidi L|Evers, B Mark|Zaytseva, Yekaterina Y | ||||||||||
| PMID: | 30154249 | ||||||||||
| 40. | |||||||||||
| Journal: | J Surg Res. 2018 Nov;231:323-330. | ||||||||||
| Title: | Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer. | ||||||||||
| Author: | Yuza, Kizuki|Nagahashi, Masayuki|Shimada, Yoshifumi|Nakano, Mae|Tajima, Yosuke|Kameyama, Hitoshi|Nakajima, Masato|Takabe, Kazuaki|Wakai, Toshifumi | ||||||||||
| PMID: | 30278948 | ||||||||||
| 41. | |||||||||||
| Journal: | Int J Oncol. 2018 Oct 25. | ||||||||||
| Title: | Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelialmesenchymal transition mediated by the FAK/AKT/MMPs axis. | ||||||||||
| Author: | Liu, Shi-Quan|Xu, Chun-Yan|Wu, Wen-Hong|Fu, Zhen-Hua|He, Si-Wei|Qin, Meng-Bin|Huang, Jie-An | ||||||||||
| PMID: | 30365116 | ||||||||||