Primary Site >> Colorectal Cancer

Gene >> SPARC

Journal: Cell Biol Int Rep. 1992 Dec;16(12):1237-45.
Title: Modulation of extracellular matrix glycoproteins production by in vitro interacting conditions between rat colonic fibroblasts and tumoral cells.
Author: Perrin, P|Ringeard, S|Harb, J|Meflah, K|Menanteau, J
PMID: 1283839
Journal: Int J Cancer. 1995 Feb 20;64(1):70-5.
Title: Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes.
Author: Porte, H|Chastre, E|Prevot, S|Nordlinger, B|Empereur, S|Basset, P|Chambon, P|Gespach, C
PMID: 7665251
Journal: Int J Oncol. 2001 Mar;18(3):521-6.
Title: Genomic organization and chromosomal mapping of SPARC-like 1, a gene down regulated in cancers.
Author: Isler, S G|Schenk, S|Bendik, I|Schraml, P|Novotna, H|Moch, H|Sauter, G|Ludwig, C U
PMID: 11179481
Journal: J Cell Biochem. 2001;81(3):463-76.
Title: Expression of SPARC/osteonectin/BM4O in the human gut: predominance in the stroma of the remodeling distal intestine.
Author: Lussier, C|Sodek, J|Beaulieu, J F
PMID: 11255229
Journal: Int J Cancer. 2002 Sep 10;101(2):118-27.
Title: Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer.
Author: Van Beijnum, Judy R|Moerkerk, Peter T M|Gerbers, Andrea J|De Bruine, Adriaan P|Arends, Jan-Willem|Hoogenboom, Hennie R|Hufton, Simon E
PMID: 12209988
Journal: Proteomics. 2004 May;4(5):1324-34.
Title: Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.
Author: Volmer, Martin W|Radacz, Yvonne|Hahn, Stephan A|Klein-Scory, Susanne|Stuhler, Kai|Zapatka, Marc|Schmiegel, Wolff|Meyer, Helmut E|Schwarte-Waldhoff, Irmgard
PMID: 15188399
Journal: Prostaglandins Leukot Essent Fatty Acids. 2005 Apr;72(4):273-8.
Title: Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells.
Author: Watkins, Gareth|Martin, Tracey A|Bryce, Richard|Mansel, Robert E|Jiang, Wen G
PMID: 15763439
Journal: J Clin Invest. 2005 Jun;115(6):1492-502. Epub 2005 May 12.
Title: Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy.
Author: Tai, Isabella T|Dai, Meiru|Owen, David A|Chen, Lan Bo
PMID: 15902309
Journal: Oncogene. 2005 Dec 15;24(56):8240-51.
Title: Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment.
Author: Nguyen, Quang-De|De Wever, Olivier|Bruyneel, Erik|Hendrix, An|Xie, Wan-Zhuo|Lombet, Alain|Leibl, Martin|Mareel, Marc|Gieseler, Frank|Bracke, Marc|Gespach, Christian
PMID: 16091733
Journal: Mol Cell Proteomics. 2006 Aug;5(8):1471-83.
Title: Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.
Author: Madoz-Gurpide, Juan|Lopez-Serra, Paula|Martinez-Torrecuadrada, Jorge Luis|Sanchez, Lydia|Lombardia, Luis|Casal, J Ignacio
PMID: 16733264
Journal: J Biol Chem. 2007 Nov 23;282(47):34457-67. Epub 2007 Sep 26.
Title: A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers.
Author: Tang, Michelle J|Tai, Isabella T
PMID: 17897953
Journal: Cancer Detect Prev. 2007;31(4):282-95.
Title: Identification of gene signatures for invasive colorectal tumor cells.
Author: Wiese, Anja H|Auer, Johannes|Lassmann, Silke|Nahrig, Jorg|Rosenberg, Robert|Hofler, Heinz|Ruger, Rudiger|Werner, Martin
PMID: 17936523
Journal: Genome Biol. 2007;8(7):R131.
Title: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.
Author: Kaiser, Sergio|Park, Young-Kyu|Franklin, Jeffrey L|Halberg, Richard B|Yu, Ming|Jessen, Walter J|Freudenberg, Johannes|Chen, Xiaodi|Haigis, Kevin|Jegga, Anil G|Kong, Sue|Sakthivel, Bhuvaneswari|Xu, Huan|Reichling, Timothy|Azhar, Mohammad|Boivin, Gregory P|
PMID: 17615082
Journal: Int J Cancer. 2007 Aug 1;121(3):567-75.
Title: Frequent inactivation of SPARC by promoter hypermethylation in colon cancers.
Author: Yang, Eungi|Kang, Hyun Ju|Koh, Kwi Hye|Rhee, Hwanseok|Kim, Nam Kyu|Kim, Hoguen
PMID: 17397030
Journal: Gut. 2007 Oct;56(10):1410-4. Epub 2007 Feb 13.
Title: Deficiency of SPARC suppresses intestinal tumorigenesis in APCMin/+ mice.
Author: Sansom, Owen J|Mansergh, Fiona C|Evans, Martin J|Wilkins, Julie A|Clarke, Alan R
PMID: 17299058
Journal: Mol Cancer Ther. 2007 Jan;6(1):309-17.
Title: Synergism between vitamin D and secreted protein acidic and rich in cysteine-induced apoptosis and growth inhibition results in increased susceptibility of therapy-resistant colorectal cancer cells to chemotherapy.
Author: Taghizadeh, Farnaz|Tang, Michelle J|Tai, Isabella T
PMID: 17237289
Journal: Br J Cancer. 2008 Jun 3;98(11):1810-9.
Title: SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.
Author: Cheetham, S|Tang, M J|Mesak, F|Kennecke, H|Owen, D|Tai, I T
PMID: 18458674
Journal: Drug Resist Updat. 2008 Dec;11(6):231-46.
Title: SPARC in cancer biology: its role in cancer progression and potential for therapy.
Author: Tai, Isabella T|Tang, Michelle J
PMID: 18849185
Journal: Front Biosci (Schol Ed). 2009 Jun 1;1:216-25.
Title: Tumor endothelium is characterized by a matrix remodeling signature.
Author: van Beijnum, Judy R|Petersen, Kjell|Griffioen, Arjan W
PMID: 19482697
Journal: Brain Pathol. 2010 Jan;20(1):200-10.
Title: Reduced activity of CD13/aminopeptidase N (APN) in aggressive meningiomas is associated with increased levels of SPARC.
Author: Mawrin, Christian|Wolke, Carmen|Haase, Daniela|Kruger, Sabine|Firsching, Raimund|Keilhoff, Gerburg|Paulus, Werner|Gutmann, David H|Lal, Anita|Lendeckel, Uwe
PMID: 19236378
Journal: Int J Cancer. 2010 Sep 1;127(6):1393-403.
Title: Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Author: Inoue, Mitsuhiro|Senju, Satoru|Hirata, Shinya|Ikuta, Yoshiaki|Hayashida, Yuki|Irie, Atsushi|Harao, Michiko|Imai, Katsunori|Tomita, Yusuke|Tsunoda, Takuya|Furukawa, Yoichi|Ito, Takaaki|Nakamura, Yusuke|Baba, Hideo|Nishimura, Yasuharu
PMID: 20063317
Journal: Carcinogenesis. 2010 May;31(5):812-9.
Title: Secreted protein acidic and rich in cysteine-induced cellular senescence in colorectal cancers in response to irinotecan is mediated by P53.
Author: Chan, Justin M|Ho, Shirley H|Tai, Isabella T
PMID: 20164124
Journal: J Exp Clin Cancer Res. 2010 Jun 16;29:71.
Title: Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer.
Author: Liang, Jian-fang|Wang, Hong-kun|Xiao, Hong|Li, Ning|Cheng, Cai-xia|Zhao, Yu-ze|Ma, Yan-b|Gao, Jian-zhong|Bai, Rui-bing|Zheng, Hui-xia
PMID: 20565704
Journal: Epigenetics. 2011 Aug;6(8):1001-11.
Title: Lymphovascular invasion of colorectal cancer is correlated to SPARC expression in the tumor stromal microenvironment.
Author: Yoshimura, Tetsunori|Nagahara, Makoto|Kuo, Christine|Turner, Roderick R|Soon-Shiong, Patrick|Hoon, Dave S B
PMID: 21725199
Journal: PLoS One. 2011;6(7):e22047.
Title: SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer.
Author: Chew, Angela|Salama, Paul|Robbshaw, Anneli|Klopcic, Borut|Zeps, Nikolajs|Platell, Cameron|Lawrance, Ian C
PMID: 21818290
Journal: Cancer Lett. 2013 Jan 1;328(1):10-7.
Title: SPARC and DNA methylation: possible diagnostic and therapeutic implications in gastrointestinal cancers.
Author: Nagaraju, Ganji Purnachandra|El-Rayes, Bassel F
PMID: 22939997
Journal: Przegl Lek. 2013;70(11):969-72.
Title: [Physical activity in prevention and treatment of colon cancer].
Author: Gilbert, Anna|Czarkowska-Paczek, Bozena|Deptala, Andrzej
PMID: 24697040
Journal: BMC Bioinformatics. 2013;14 Suppl 9:S1.
Title: Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets.
Author: Xu, Xiao|Zhang, Yuanhao|Williams, Jennie|Antoniou, Eric|McCombie, W Richard|Wu, Song|Zhu, Wei|Davidson, Nicholas O|Denoya, Paula|Li, Ellen
PMID: 23902433
Journal: Ann Coloproctol. 2013 Jun;29(3):93-9.
Title: Expression of Secreted Protein Acidic and Rich in Cysteine in the Stroma of a Colorectal Carcinoma is Associated With Patient Prognosis.
Author: Kim, Jeong Yeon|Jeong, Dongjun|Ahn, Tae Sung|Kim, Hyung Ju|Park, Doo San|Park, So Yong|Bae, Sang Byung|Lee, Sookyoung|Lee, Sung Soo|Lee, Moon Soo|Cho, Hyun Deuk|Baek, Moo Jun
PMID: 23862126
Journal: Oncology. 2013;84(2):81-91.
Title: Relationship between the expression of the extracellular matrix genes SPARC, SPP1, FN1, ITGA5 and ITGAV and clinicopathological parameters of tumor progression and colorectal cancer dissemination.
Author: Viana, Luciano de Souza|Affonso, Renato Jose Jr|Silva, Sandra Regina Morini|Denadai, Marcos Vinicius Araujo|Matos, Delcio|Salinas de Souza, Carolina|Waisberg, Jaques
PMID: 23128103
Journal: Gut. 2013 Jun;62(6):810-1.
Title: Exercise-induced SPARC prevents tumorigenesis of colon cancer.
Author: Liu, Yu-Peng|Hsiao, Michael
PMID: 23086830
Journal: Gut. 2013 Jun;62(6):882-9.
Title: A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise.
Author: Aoi, Wataru|Naito, Yuji|Takagi, Tomohisa|Tanimura, Yuko|Takanami, Yoshikazu|Kawai, Yukari|Sakuma, Kunihiro|Hang, Liu Po|Mizushima, Katsura|Hirai, Yasuko|Koyama, Ryota|Wada, Sayori|Higashi, Akane|Kokura, Satoshi|Ichikawa, Hiroshi|Yoshikawa, Toshikazu
PMID: 22851666
Journal: Cancer Metastasis Rev. 2013 Dec;32(3-4):585-602.
Title: Stromal expression of SPARC in pancreatic adenocarcinoma.
Author: Neuzillet, Cindy|Tijeras-Raballand, Annemilai|Cros, Jerome|Faivre, Sandrine|Hammel, Pascal|Raymond, Eric
PMID: 23690170
Journal: Mod Pathol. 2014 Jun;27(6):906-15.
Title: Differential survival trends of stage II colorectal cancer patients relate to promoter methylation status of PCDH10, SPARC, and UCHL1.
Author: Heitzer, Ellen|Artl, Monika|Filipits, Martin|Resel, Margit|Graf, Ricarda|Weissenbacher, Bettina|Lax, Sigurd|Gnant, Michael|Wrba, Fritz|Greil, Richard|Dietze, Otto|Hofbauer, Friedrich|Bohm, Gerhard|Hofler, Gerald|Samonigg, Hellmut|Schaberl-Moser, Renate|Ba
PMID: 24309322
Journal: Ann Clin Lab Sci. 2014 Winter;44(1):99-103.
Title: Heterotopic ossification in metastatic colorectal carcinoma: case report with morphoproteomic insights into the histogenesis.
Author: Huang, Richard Sheng Poe|Brown, Robert E|Buryanek, Jamie
PMID: 24695482
Journal: Curr Pharm Des. 2014;20(39):6182-90.
Title: SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target.
Author: Feng, Jianguo|Tang, Liling
PMID: 24947586
Journal: Anticancer Res. 2014 Oct;34(10):5599-607.
Title: Overexpression of the ITGAV gene is associated with progression and spread of colorectal cancer.
Author: Waisberg, Jaques|De Souza Viana, Luciano|Affonso Junior, Renato Jose|Silva, Sandra Regina Morini|Denadai, Marcos Vinicius Araujo|Margeotto, Fernando Beani|De Souza, Carolina Salinas|Matos, Delcio
PMID: 25275062
Journal: Eur Rev Med Pharmacol Sci. 2015 May;19(10):1803-11.
Title: Secreted protein acidic and rich in cysteine expression in human colorectal cancer predicts postoperative prognosis.
Author: Liu, Q-Z|Gao, X-H|Chang, W-J|Wang, H-T|Wang, H|Cao, G-W|Fu, C-G
PMID: 26044224
Journal: PLoS One. 2015 Dec 16;10(12):e0144333.
Title: Genetic and Immunohistochemical Expression of Integrins ITGAV, ITGA6, and ITGA3 As Prognostic Factor for Colorectal Cancer: Models for Global and Disease-Free Survival.
Author: Linhares, Marcelo Moura|Affonso, Renato Jose Jr|Viana, Luciano de Souza|Silva, Sandra Regina Morini|Denadai, Marcos Vinicius Araujo|de Toledo, Silvia Regina Caminada|Matos, Delcio
PMID: 26674523
Journal: Oncol Res. 2016 Oct 27;24(6):437-445.
Title: Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway.
Author: Zhao, Ping|Guan, Hai-Tao|Dai, Zhi-Jun|Ma, Yu-Guang|Liu, Xiao-Xu|Wang, Xi-Jing
PMID: 28281964
Journal: Tumour Biol. 2016 Feb;37(2):2267-73.
Title: Secreted protein acidic and rich in cysteine enhances the chemosensitivity of pancreatic cancer cells to gemcitabine.
Author: Fan, Xin|Mao, Zhengfa|Ma, Xiaoyan|Cui, Lei|Qu, Jianguo|Lv, Lihui|Dang, ShengChun|Wang, Xuqing|Zhang, Jianxin
PMID: 26358255
Journal: Cancer Biomark. 2017;18(4):459-466.
Title: SPARC: As a prognostic biomarker in rectal cancer patients treated with chemo-radiotherapy.
Author: Kurtul, Neslihan|Tasdemir, Erdem Arzu|Unal, Dilek|Izmirli, Mustafa|Eroglu, Celalettin
PMID: 28009327
Journal: JCI Insight. 2017 Jan 12;2(1):e91419.
Title: Metastasis regulation by PPARD expression in cancer cells.
Author: Zuo, Xiangsheng|Xu, Weiguo|Xu, Min|Tian, Rui|Moussalli, Micheline J|Mao, Fei|Zheng, Xiaofeng|Wang, Jing|Morris, Jeffrey S|Gagea, Mihai|Eng, Cathy|Kopetz, Scott|Maru, Dipen M|Rashid, Asif|Broaddus, Russell|Wei, Daoyan|Hung, Mien-Chie|Sood, Anil K|Shureiqi,
PMID: 28097239
Journal: J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author: Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K
PMID: 28280620
Journal: Neoplasia. 2017 May;19(5):429-438.
Title: Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact.
Author: Takigawa, Hidehiko|Kitadai, Yasuhiko|Shinagawa, Kei|Yuge, Ryo|Higashi, Yukihito|Tanaka, Shinji|Yasui, Wataru|Chayama, Kazuaki
PMID: 28433772
Journal: Med Sci Sports Exerc. 2017 Sep;49(9):1805-1816.
Title: A Mechanism Underlying Preventive Effect of High-Intensity Training on Colon Cancer.
Author: Matsuo, Kaori|Sato, Koji|Suemoto, Ken|Miyamoto-Mikami, Eri|Fuku, Noriyuki|Higashida, Kazuhiko|Tsuji, Katsunori|Xu, Yuzhong|Liu, Xin|Iemitsu, Motoyuki|Hamaoka, Takafumi|Tabata, Izumi
PMID: 28463901
Journal: Cancer Lett. 2017 Aug 28;402:110-116.
Title: Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author: Nagaraju, Ganji Purnachandra|Wu, Christina|Merchant, Neha|Chen, Zhengjia|Lesinski, Gregory B|El-Rayes, Bassel F
PMID: 28583846
Journal: Mol Med Rep. 2017 Nov;16(5):6499-6505.
Title: Colon cancer recurrenceassociated genes revealed by WGCNA coexpression network analysis.
Author: Zhai, Xiaofeng|Xue, Qingfeng|Liu, Qun|Guo, Yuyu|Chen, Zhe
PMID: 28901407
Journal: Oncotarget. 2017 Nov 10;8(61):104508-104524.
Title: hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC.
Author: Zhang, Shitong|Jin, Jianjun|Tian, Xiaoxiao|Wu, Lijuan
PMID: 29262657
Journal: Oncotarget. 2017 Dec 27;9(5):6086-6094.
Title: Construction of key signal regulatory network in metastatic colorectal cancer.
Author: Qi, Lu|Ding, Yanqing
PMID: 29464057
Journal: Development. 2018 Mar 14;145(6). pii: dev.153049.
Title: Identification, isolation and characterization of human LGR5-positive colon adenoma cells.
Author: Dame, Michael K|Attili, Durga|McClintock, Shannon D|Dedhia, Priya H|Ouillette, Peter|Hardt, Olaf|Chin, Alana M|Xue, Xiang|Laliberte, Julie|Katz, Erica L|Newsome, Gina M|Hill, David R|Miller, Alyssa J|Tsai, Yu-Hwai|Agorku, David|Altheim, Christopher H|Bosi
PMID: 29467240
Journal: Biomed Res Int. 2018 Aug 6;2018:9416515.
Title: Bioinformatics Analysis Reveals Most Prominent Gene Candidates to Distinguish Colorectal Adenoma from Adenocarcinoma.
Author: Hauptman, Nina|Bostjancic, Emanuela|Zlajpah, Margareta|Rankovic, Branislava|Zidar, Nina
PMID: 30175151