Primary Site >> Colorectal Cancer

Gene >> SOX9

Journal: Cancer Res. 2005 Mar 15;65(6):2193-8.
Title: Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells.
Author: Jay, Philippe|Berta, Philippe|Blache, Philippe
PMID: 15781631
Journal: Exp Cell Res. 2008 Dec 10;314(20):3712-23.
Title: KLF4 regulation in intestinal epithelial cell maturation.
Author: Flandez, M|Guilmeau, S|Blache, P|Augenlicht, L H
PMID: 18977346
Journal: Am J Clin Pathol. 2008 Dec;130(6):897-904.
Title: Analysis of SOX9 expression in colorectal cancer.
Author: Lu, Bingjian|Fang, Yihu|Xu, Jing|Wang, Lipei|Xu, Fangying|Xu, Enping|Huang, Qiong|Lai, Maode
PMID: 19019766
Journal: Rheumatology (Oxford). 2009 Nov;48(11):1435-41.
Title: Role of deleted in colon carcinoma in osteoarthritis and in chondrocyte migration.
Author: Schubert, Thomas|Kaufmann, Simone|Wenke, Ann-Kathrin|Grassel, Susanne|Bosserhoff, Anja-Katrin
PMID: 19745029
Journal: Gut. 2010 Sep;59(9):1236-44.
Title: Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.
Author: Stange, D E|Engel, F|Longerich, T|Koo, B K|Koch, M|Delhomme, N|Aigner, M|Toedt, G|Schirmacher, P|Lichter, P|Weitz, J|Radlwimmer, B
PMID: 20479215
Journal: Mol Cancer. 2010 Oct 26;9:281.
Title: IGFBP-rP1, a potential molecule associated with colon cancer differentiation.
Author: Ruan, Wenjing|Zhu, Shuzhen|Wang, Haibing|Xu, Fangying|Deng, Hong|Ma, Yu|Lai, Maode
PMID: 20977730
Journal: Future Med Chem. 2010 Jan;2(1):65-80.
Title: cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.
Author: Browning, Darren D|Kwon, In-Kiu|Wang, Rui
PMID: 21426046
Journal: BMC Genomics. 2011 Oct 14;12:505.
Title: Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis.
Author: Thorsen, Kasper|Schepeler, Troels|Oster, Bodil|Rasmussen, Mads H|Vang, Soren|Wang, Kai|Hansen, Kristian Q|Lamy, Philippe|Pedersen, Jakob Skou|Eller, Asger|Mansilla, Francisco|Laurila, Kirsti|Wiuf, Carsten|Laurberg, Soren|Dyrskjot, Lars|Orntoft, Torben F|A
PMID: 21999571
Journal: Oncogene. 2011 Jun 2;30(22):2493-503.
Title: MiniSOX9, a dominant-negative variant in colon cancer cells.
Author: Abdel-Samad, R|Zalzali, H|Rammah, C|Giraud, J|Naudin, C|Dupasquier, S|Poulat, F|Boizet-Bonhoure, B|Lumbroso, S|Mouzat, K|Bonnans, C|Pignodel, C|Raynaud, P|Fort, P|Quittau-Prevostel, C|Blache, P
PMID: 21297661
Journal: Oncogene. 2011 Jun 9;30(23):2659-69.
Title: Loss of a single Hic1 allele accelerates polyp formation in Apc(Delta716) mice.
Author: Mohammad, H P|Zhang, W|Prevas, H S|Leadem, B R|Zhang, M|Herman, J G|Hooker, C M|Watkins, D N|Karim, B|Huso, D L|Baylin, S B
PMID: 21297660
Journal: Cancer Res. 2012 Mar 1;72(5):1301-15.
Title: Oncogenicity of the developmental transcription factor Sox9.
Author: Matheu, Ander|Collado, Manuel|Wise, Clare|Manterola, Lorea|Cekaite, Lina|Tye, Angela J|Canamero, Marta|Bujanda, Luis|Schedl, Andreas|Cheah, Kathryn S E|Skotheim, Rolf I|Lothe, Ragnhild A|Lopez de Munain, Adolfo|Briscoe, James|Serrano, Manuel|Lovell-Badge,
PMID: 22246670
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15;303(2):G209-19.
Title: Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa.
Author: Wang, Rui|Kwon, In-Kiu|Thangaraju, Muthusamy|Singh, Nagendra|Liu, Kebin|Jay, Philippe|Hofmann, Franz|Ganapathy, Vadivel|Browning, Darren D
PMID: 22556146
Journal: Nature. 2012 Jul 18;487(7407):330-7.
Title: Comprehensive molecular characterization of human colon and rectal cancer.
Author:
PMID: 22810696
Journal: Carcinogenesis. 2012 Dec;33(12):2311-9.
Title: Splice isoforms as therapeutic targets for colorectal cancer.
Author: Miura, Koh|Fujibuchi, Wataru|Unno, Michiaki
PMID: 23118106
Journal: Biochim Biophys Acta. 2013 Aug;1833(8):1853-65.
Title: Interplay between SOX9, beta-catenin and PPARgamma activation in colorectal cancer.
Author: Panza, Anna|Pazienza, Valerio|Ripoli, Maria|Benegiamo, Giorgia|Gentile, Annamaria|Valvano, Maria Rosaria|Augello, Bartolomeo|Merla, Giuseppe|Prattichizzo, Clelia|Tavano, Francesca|Ranieri, Elena|di Sebastiano, Pierluigi|Vinciguerra, Manlio|Andriulli, Ange
PMID: 23583560
Journal: Cancer Biomark. 2013;13(4):269-79.
Title: Tumorigenesis and tumor progression related gene expression profiles in colorectal cancer.
Author: Huang, Ming-Yii|Chen, Hung-Chang|Yang, I-Ping|Tsai, Hsiang-Lin|Wang, Tsu-Nai|Juo, Suh-Hang Hank|Wang, Jaw-Yuan
PMID: 24240588
Journal: J Cell Sci. 2013 Dec 15;126(Pt 24):5645-56.
Title: Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation.
Author: Andres, Sarah F|Simmons, James G|Mah, Amanda T|Santoro, M Agostina|Van Landeghem, Laurianne|Lund, P Kay
PMID: 24127567
Journal: PLoS One. 2013 Sep 25;8(9):e75421.
Title: Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation.
Author: Bobinet, Mathilde|Vignard, Virginie|Florenceau, Laetitia|Lang, Francois|Labarriere, Nathalie|Moreau-Aubry, Agnes
PMID: 24086527
Journal: Gut Liver. 2013 Sep;7(5):513-8.
Title: SOX9 Is Highly Expressed in Nonampullary Duodenal Adenoma and Adenocarcinoma in Humans.
Author: Sakamoto, Hirotsugu|Mutoh, Hiroyuki|Miura, Yoshimasa|Sashikawa, Miho|Yamamoto, Hironori|Sugano, Kentaro
PMID: 24073307
Journal: Br J Cancer. 2013 Aug 20;109(4):1023-30.
Title: Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.
Author: Candy, P A|Phillips, M R|Redfern, A D|Colley, S M|Davidson, J A|Stuart, L M|Wood, B A|Zeps, N|Leedman, P J
PMID: 23900217
Journal: Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G74-83.
Title: SOX9 directly regulates IGFBP-4 in the intestinal epithelium.
Author: Shi, Zhongcheng|Chiang, Chi-I|Mistretta, Toni-Ann|Major, Angela|Mori-Akiyama, Yuko
PMID: 23660500
Journal: Carcinogenesis. 2014 Mar;35(3):606-12.
Title: Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.
Author: Fan, Yang-Yi|Davidson, Laurie A|Callaway, Evelyn S|Goldsby, Jennifer S|Chapkin, Robert S
PMID: 24336194
Journal: Dev Biol. 2014 Mar 15;387(2):191-202.
Title: Inducible intestine-specific deletion of Kruppel-like factor 5 is characterized by a regenerative response in adult mouse colon.
Author: Nandan, Mandayam O|Ghaleb, Amr M|Liu, Yang|Bialkowska, Agnieszka B|McConnell, Beth B|Shroyer, Kenneth R|Robine, Sylvie|Yang, Vincent W
PMID: 24440658
Journal: Biochim Biophys Acta. 2014 Jun;1843(6):1225-36.
Title: Peroxisome proliferator-activated receptor gamma-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer.
Author: Panza, Anna|Votino, Carolina|Gentile, Annamaria|Valvano, Maria Rosaria|Colangelo, Tommaso|Pancione, Massimo|Micale, Lucia|Merla, Giuseppe|Andriulli, Angelo|Sabatino, Lina|Vinciguerra, Manlio|Prattichizzo, Clelia|Mazzoccoli, Gianluigi|Colantuoni, Vittorio|
PMID: 24631504
Journal: Front Oncol. 2014 May 21;4:118.
Title: Prognostic Significance of beta-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series.
Author: Bruun, Jarle|Kolberg, Matthias|Nesland, Jahn M|Svindland, Aud|Nesbakken, Arild|Lothe, Ragnhild A
PMID: 24904831
Journal: Mol Ther. 2014 Sep;22(9):1653-64.
Title: KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis.
Author: Park, So-Yeon|Kim, Hangun|Yoon, Somy|Bae, Jeong A|Choi, Seok-Yong|Jung, Young Do|Kim, Kyung Keun
PMID: 24909917
Journal: Mol Med Rep. 2015 Sep;12(3):4508-4513.
Title: Triptolide suppresses proliferation, hypoxia-inducible factor-1alpha and c-Myc expression in pancreatic cancer cells.
Author: Ding, Xiaoling|Zhou, Xiaorong|Jiang, Bo|Zhao, Qun|Zhou, Guoxiong
PMID: 26094625
Journal: J Crohns Colitis. 2015 Jul;9(7):565-74.
Title: Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
Author: Suzuki, Ryo|Fukui, Toshiro|Kishimoto, Masanobu|Miyamoto, Sachi|Takahashi, Yu|Takeo, Masahiro|Mitsuyama, Toshiyuki|Sakaguchi, Yutaku|Uchida, Kazushige|Nishio, Akiyoshi|Okazaki, Kazuichi
PMID: 25908723
Journal: Nucleic Acids Res. 2015 Jul 27;43(13):6257-69.
Title: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells.
Author: Shi, Zhongcheng|Chiang, Chi-I|Labhart, Paul|Zhao, Yanling|Yang, Jianhua|Mistretta, Toni-Ann|Henning, Susan J|Maity, Sankar N|Mori-Akiyama, Yuko
PMID: 26040697
Journal: Clin Colorectal Cancer. 2015 Jun;14(2):63-71.
Title: Clinical implications of intestinal stem cell markers in colorectal cancer.
Author: Espersen, Maiken Lise Marcker|Olsen, Jesper|Linnemann, Dorte|Hogdall, Estrid|Troelsen, Jesper T
PMID: 25657049
Journal: Oncotarget. 2015 Aug 21;6(24):20672-84.
Title: Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma.
Author: Shen, Zhiyong|Deng, Haijun|Fang, Yuan|Zhu, Xianjun|Ye, Geng-Tai|Yan, Li|Liu, Hao|Li, Guoxin
PMID: 26009899
Journal: Gut. 2016 Sep;65(9):1470-81.
Title: Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer.
Author: Shi, Chenzhang|Yang, Yongzhi|Xia, Yang|Okugawa, Yoshinaga|Yang, Jun|Liang, Yong|Chen, Hongqi|Zhang, Peng|Wang, Feng|Han, Huazhong|Wu, Wen|Gao, Renyuan|Gasche, Christoph|Qin, Huanlong|Ma, Yanlei|Goel, Ajay
PMID: 25994220
Journal: Gastroenterology. 2016 Apr;150(4):931-43.
Title: Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Author: Robles, Ana I|Traverso, Giovanni|Zhang, Ming|Roberts, Nicholas J|Khan, Mohammed A|Joseph, Christine|Lauwers, Gregory Y|Selaru, Florin M|Popoli, Maria|Pittman, Meredith E|Ke, Xiquan|Hruban, Ralph H|Meltzer, Stephen J|Kinzler, Kenneth W|Vogelstein, Bert|Har
PMID: 26764183
Journal: Hum Pathol. 2016 Jun;52:38-46.
Title: SOX9 expression predicts relapse of stage II colon cancer patients.
Author: Marcker Espersen, Maiken Lise|Linnemann, Dorte|Christensen, Ib Jarle|Alamili, Mahdi|Troelsen, Jesper T|Hogdall, Estrid
PMID: 26980019
Journal: Oncotarget. 2016 Aug 9;7(32):50875-50882.
Title: Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.
Author: Javier, Breanna M|Yaeger, Rona|Wang, Lu|Sanchez-Vega, Francisco|Zehir, Ahmet|Middha, Sumit|Sadowska, Justyna|Vakiani, Efsevia|Shia, Jinru|Klimstra, David|Ladanyi, Marc|Iacobuzio-Donahue, Christine A|Hechtman, Jaclyn F
PMID: 27248473
Journal: Oncotarget. 2016 Dec 13;7(50):82228-82243.
Title: SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ss-catenin signaling.
Author: Prevostel, Corinne|Rammah-Bouazza, Cyrine|Trauchessec, Helene|Canterel-Thouennon, Lucile|Busson, Muriel|Ychou, Marc|Blache, Philippe
PMID: 27429045
Journal: Oncotarget. 2016 Sep 13;7(37):59144-59157.
Title: Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ss-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1.
Author: Montorsi, Lucia|Guizzetti, Filippo|Alecci, Claudia|Caporali, Andrea|Martello, Andrea|Atene, Claudio Giacinto|Parenti, Sandra|Pizzini, Silvia|Zanovello, Paola|Bortoluzzi, Stefania|Ferrari, Sergio|Grande, Alexis|Zanocco-Marani, Tommaso
PMID: 27463018
Journal: Sci Rep. 2016 Aug 30;6:32350.
Title: SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin.
Author: Carrasco-Garcia, Estefania|Lopez, Lidia|Aldaz, Paula|Arevalo, Sara|Aldaregia, Juncal|Egana, Larraitz|Bujanda, Luis|Cheung, Martin|Sampron, Nicolas|Garcia, Idoia|Matheu, Ander
PMID: 27571710
Journal: Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2126-2134.
Title: Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes.
Author: Carvajal, Ana E|Serrano-Morales, Jose M|Vazquez-Carretero, Maria D|Garcia-Miranda, Pablo|Calonge, Maria L|Peral, Maria J|Ilundain, Anunciacion A
PMID: 28572005
Journal: Sci Rep. 2017 Nov 21;7(1):15918.
Title: Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9.
Author: Choi, Bae-Jung|Park, Sin-Aye|Lee, Sung-Young|Cha, Young Nam|Surh, Young-Joon
PMID: 29162839
Journal: Eur J Cancer. 2017 Nov;86:150-157.
Title: The dose-dependent effect of SOX9 and its incidence in colorectal cancer.
Author: Prevostel, Corinne|Blache, Philippe
PMID: 28988015
Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K
PMID: 28675510
Journal: Nat Commun. 2017 Apr 28;8:15008.
Title: HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
Author: Xian, Lingling|Georgess, Dan|Huso, Tait|Cope, Leslie|Belton, Amy|Chang, Yu-Ting|Kuang, Wenyong|Gu, Qihua|Zhang, Xiaoyan|Senger, Stefania|Fasano, Alessio|Huso, David L|Ewald, Andrew J|Resar, Linda M S
PMID: 28452345
Journal: Oncol Res Treat. 2017;40(1-2):15-20.
Title: Expression and Clinical Significance of SOX9 in Renal Cell Carcinoma, Bladder Cancer and Penile Cancer.
Author: Wan, Yue-Ping|Xi, Ming|He, Hui-Chan|Wan, Song|Hua, Wei|Zen, Zhao-Chang|Liu, Yuan-Ling|Zhou, Yu-Lin|Mo, Ru-Jun|Zhuo, Yang-Jia|Luo, Hong-Wei|Jiang, Fu-Neng|Zhong, Wei-De
PMID: 28118628
Journal: Biochem Biophys Res Commun. 2017 Jan 29;483(1):475-481.
Title: Sox9 mediated transcriptional activation of FOXK2 is critical for colorectal cancer cells proliferation.
Author: Qian, Yu|Xia, Suhua|Feng, Zhenyu
PMID: 28007600
Journal: Oncotarget. 2017 Jan 31;8(5):7852-7866.
Title: Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Author: Ashktorab, Hassan|Mokarram, Pooneh|Azimi, Hamed|Olumi, Hasti|Varma, Sudhir|Nickerson, Michael L|Brim, Hassan
PMID: 28002797
Journal: Cancer Lett. 2018 May 1;421:161-169.
Title: Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author: Lin, Yun-Kai|Fang, Zheng|Jiang, Tian-Yi|Wan, Zheng-Hua|Pan, Yu-Fei|Ma, Yun-Han|Shi, Yuan-Yuan|Tan, Ye-Xiong|Dong, Li-Wei|Zhang, Yong-Jie|Wang, Hong-Yang
PMID: 29452147
Journal: Genes Chromosomes Cancer. 2018 Jul;57(7):366-376.
Title: Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.
Author: Wolff, Roger K|Hoffman, Michael D|Wolff, Erica C|Herrick, Jennifer S|Sakoda, Lori C|Samowitz, Wade S|Slattery, Martha L
PMID: 29575536
Journal: Cancer Res. 2018 Apr 15;78(8):1890-1897.
Title: Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.
Author: Resar, Linda|Chia, Lionel|Xian, Lingling
PMID: 29618461
Journal: Iran Biomed J. 2018 May 30.
Title: Differential Connectivity in Colorectal Cancer Gene Expression Network
Author: Izadi, Fereshteh
PMID: 29843204
Journal: Nucleic Acids Res. 2018 Sep 28;46(17):9106-9118.
Title: SOX9 has distinct regulatory roles in alternative splicing and transcription.
Author: Girardot, Michael|Bayet, Elsa|Maurin, Justine|Fort, Philippe|Roux, Pierre|Raynaud, Peggy
PMID: 29901772
Journal: Oncogenesis. 2018 Jul 22;7(7):55.
Title: Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer.
Author: De Nicola, Francesca|Goeman, Frauke|Pallocca, Matteo|Sperati, Francesca|Pizzuti, Laura|Melucci, Elisa|Casini, Beatrice|Amoreo, Carla Azzurra|Gallo, Enzo|Diodoro, Maria Grazia|Buglioni, Simonetta|Mazzotta, Marco|Vici, Patrizia|Sergi, Domenico|Di Lauro, Lui
PMID: 30032163
Journal: Sci Rep. 2018 Aug 24;8(1):12746.
Title: PR-LncRNA signature regulates glioma cell activity through expression of SOX factors.
Author: Torres-Bayona, Sergio|Aldaz, Paula|Auzmendi-Iriarte, Jaione|Saenz-Antonanzas, Ander|Garcia, Idoia|Arrazola, Mariano|Gerovska, Daniela|Undabeitia, Jose|Querejeta, Arrate|Egana, Larraitz|Villanua, Jorge|Ruiz, Irune|Sarasqueta, Cristina|Urculo, Enrique|Arauz
PMID: 30143669
Journal: Carcinogenesis. 2018 Sep 15. pii: 5098274.
Title: Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans.
Author: Xicola, Rosa M|Manojlovic, Zarko|Augustus, Gaius J|Kupfer, Sonia S|Emmadi, Rajyasree|Alagiozian-Angelova, Victoria|Triche, Tim Jr|Salhia, Bodour|Carpten, John|Llor, Xavier|Ellis, Nathan A
PMID: 30239619
Journal: Mol Med. 2018 Oct 3;24(1):52.
Title: The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9.
Author: Xu, Yuanlin|Zhang, Xihong|Hu, Xiufeng|Zhou, Wenping|Zhang, Peipei|Zhang, Jiuyang|Yang, Shujun|Liu, Yanyan
PMID: 30285605