Primary Site >> Colorectal Cancer
Gene >> SOX9
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Ref: Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells. PMID: 15781631 |
Ref: KLF4 regulation in intestinal epithelial cell maturation. PMID: 18977346 Ref: Analysis of SOX9 expression in colorectal cancer. PMID: 19019766 |
Ref: Role of deleted in colon carcinoma in osteoarthritis and in chondrocyte migration. PMID: 19745029 |
Ref: Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain. PMID: 20479215 Ref: IGFBP-rP1, a potential molecule associated with colon cancer differentiation. PMID: 20977730 Ref: cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment. PMID: 21426046 |
Ref: Loss of a single Hic1 allele accelerates polyp formation in Apc(Delta716) mice. PMID: 21297660 Ref: MiniSOX9, a dominant-negative variant in colon cancer cells. PMID: 21297661 Ref: Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. PMID: 21999571 |
Ref: Oncogenicity of the developmental transcription factor Sox9. PMID: 22246670 Ref: Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa. PMID: 22556146 Ref: Comprehensive molecular characterization of human colon and rectal cancer. PMID: 22810696 Ref: Splice isoforms as therapeutic targets for colorectal cancer. PMID: 23118106 |
Ref: Interplay between SOX9, beta-catenin and PPARgamma activation in colorectal cancer. PMID: 23583560 Ref: SOX9 directly regulates IGFBP-4 in the intestinal epithelium. PMID: 23660500 Ref: Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients. PMID: 23900217 Ref: SOX9 Is Highly Expressed in Nonampullary Duodenal Adenoma and Adenocarcinoma in Humans. PMID: 24073307 Ref: Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation. PMID: 24086527 Ref: Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation. PMID: 24127567 Ref: Tumorigenesis and tumor progression related gene expression profiles in colorectal cancer. PMID: 24240588 |
Ref: Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells. PMID: 24336194 Ref: Inducible intestine-specific deletion of Kruppel-like factor 5 is characterized by a regenerative response in adult mouse colon. PMID: 24440658 Ref: Peroxisome proliferator-activated receptor gamma-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer. PMID: 24631504 Ref: Prognostic Significance of beta-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series. PMID: 24904831 Ref: KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis. PMID: 24909917 |
Ref: Clinical implications of intestinal stem cell markers in colorectal cancer. PMID: 25657049 Ref: Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer. PMID: 25908723 Ref: Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma. PMID: 26009899 Ref: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells. PMID: 26040697 Ref: Triptolide suppresses proliferation, hypoxia-inducible factor-1alpha and c-Myc expression in pancreatic cancer cells. PMID: 26094625 |
Ref: Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer. PMID: 25994220 Ref: Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers. PMID: 26764183 Ref: SOX9 expression predicts relapse of stage II colon cancer patients. PMID: 26980019 Ref: Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma. PMID: 27248473 Ref: SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ss-catenin signaling. PMID: 27429045 Ref: Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ss-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1. PMID: 27463018 Ref: SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin. PMID: 27571710 |
Ref: Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer. PMID: 28002797 Ref: Sox9 mediated transcriptional activation of FOXK2 is critical for colorectal cancer cells proliferation. PMID: 28007600 Ref: Expression and Clinical Significance of SOX9 in Renal Cell Carcinoma, Bladder Cancer and Penile Cancer. PMID: 28118628 Ref: HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche. PMID: 28452345 Ref: Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes. PMID: 28572005 Ref: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. PMID: 28675510 Ref: The dose-dependent effect of SOX9 and its incidence in colorectal cancer. PMID: 28988015 Ref: Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9. PMID: 29162839 |
Ref: Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy. PMID: 29452147 Ref: Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers. PMID: 29575536 Ref: Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression. PMID: 29618461 Ref: Differential Connectivity in Colorectal Cancer Gene Expression Network PMID: 29843204 Ref: SOX9 has distinct regulatory roles in alternative splicing and transcription. PMID: 29901772 Ref: Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer. PMID: 30032163 Ref: PR-LncRNA signature regulates glioma cell activity through expression of SOX factors. PMID: 30143669 Ref: Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans. PMID: 30239619 Ref: The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9. PMID: 30285605 |