Primary Site >> Colorectal Cancer

Gene >> SOCS1

Journal: J Gastroenterol. 2004;39(2):120-4.
Title: Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients.
Author: Fujitake, Shinichi|Hibi, Kenji|Okochi, Osamu|Kodera, Yasuhiro|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 15074307
Journal: Oncol Rep. 2004 Feb;11(2):341-8.
Title: Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features.
Author: Lin, Shyr-Yi|Yeh, Kun-Tu|Chen, Willian Tzu-Liang|Chen, Hung-Chang|Chen, Shou-Tung|Chiou, Hung-Yi|Chang, Jan-Gowth
PMID: 14719065
Journal: Int J Cancer. 2004 Dec 10;112(5):846-53.
Title: Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.
Author: Bai, Alfa H C|Tong, Joanna H M|To, Ka-Fai|Chan, Michael W Y|Man, Ellen P S|Lo, Kwok-Wai|Lee, Janet F Y|Sung, Joseph J Y|Leung, Wai K
PMID: 15386372
Journal: J Invest Dermatol. 2006 Feb;126(2):422-31.
Title: Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma.
Author: Marini, Alessandra|Mirmohammadsadegh, Alireza|Nambiar, Sandeep|Gustrau, Annett|Ruzicka, Thomas|Hengge, Ulrich R
PMID: 16374457
Journal: J Exp Med. 2006 Jun 12;203(6):1391-7. Epub 2006 May 22.
Title: IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice.
Author: Hanada, Toshikatsu|Kobayashi, Takashi|Chinen, Takatoshi|Saeki, Kazuko|Takaki, Hiromi|Koga, Keiko|Minoda, Yasumasa|Sanada, Takahito|Yoshioka, Tomoko|Mimata, Hiromitsu|Kato, Seiya|Yoshimura, Akihiko
PMID: 16717119
Journal: Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17239930
Journal: Neoplasia. 2007 Dec;9(12):1091-8.
Title: IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 18084616
Journal: Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6.
Title: Promoter methylation status of multiple genes in uveal melanoma.
Author: Merhavi, Efrat|Cohen, Yoram|Avraham, Bat Chen R|Frenkel, Shahar|Chowers, Itay|Pe'er, Jacob|Goldenberg-Cohen, Nitza
PMID: 17898258
Journal: Neoplasia. 2007 Jul;9(7):569-77.
Title: Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Dehari, Reiko|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 17710160
Journal: Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title: MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author: Ogino, Shuji|Hazra, Aditi|Tranah, Gregory J|Kirkner, Gregory J|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Meyerhardt, Jeffrey A|Hunter, David J|Fuchs, Charles S
PMID: 17621591
Journal: J Mol Diagn. 2007 Jul;9(3):305-14.
Title: Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Kraft, Peter|Loda, Massimo|Fuchs, Charles S
PMID: 17591929
Journal: BMC Cancer. 2007 May 2;7:72.
Title: 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Ohnishi, Mutsuko|Fuchs, Charles S
PMID: 17474983
Journal: Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.
Title: CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Author: Ogino, Shuji|Meyerhardt, Jeffrey A|Kawasaki, Takako|Clark, Jeffrey W|Ryan, David P|Kulke, Matthew H|Enzinger, Peter C|Wolpin, Brian M|Loda, Massimo|Fuchs, Charles S
PMID: 17372756
Journal: Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title: Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17350669
Journal: Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title: Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Suemoto, Yuko|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 17339237
Journal: Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title: TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17270239
Journal: PLoS One. 2008;3(11):e3698.
Title: Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author: Nosho, Katsuhiko|Irahara, Natsumi|Shima, Kaori|Kure, Shoko|Kirkner, Gregory J|Schernhammer, Eva S|Hazra, Aditi|Hunter, David J|Quackenbush, John|Spiegelman, Donna|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19002263
Journal: Histopathology. 2008 Nov;53(5):588-98.
Title: Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Author: Nosho, K|Kawasaki, T|Chan, A T|Ohnishi, M|Suemoto, Y|Kirkner, G J|Fuchs, C S|Ogino, S
PMID: 18983468
Journal: Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title: CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author: Lee, Sun|Cho, Nam-Yun|Yoo, Eun Joo|Kim, Jung Ho|Kang, Gyeong Hoon
PMID: 18834226
Journal: Cancer Sci. 2008 Aug;99(8):1650-5.
Title: Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells.
Author: Takahashi, Yuki|Kaneda, Haruka|Takasuka, Nana|Hattori, Kayoko|Nishikawa, Makiya|Watanabe, Yoshihiko|Takakura, Yoshinobu
PMID: 18754879
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1774-80.
Title: Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype.
Author: English, Dallas R|Young, Joanne P|Simpson, Julie A|Jenkins, Mark A|Southey, Melissa C|Walsh, Michael D|Buchanan, Daniel D|Barker, Melissa A|Haydon, Andrew M|Royce, Simon G|Roberts, Aedan|Parry, Susan|Hopper, John L|Jass, Jeremy J|Giles, Graham G
PMID: 18628431
Journal: Int J Cancer. 2008 Jun 15;122(12):2767-73.
Title: LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S
PMID: 18366060
Journal: Mod Pathol. 2008 Mar;21(3):245-55.
Title: CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Nosho, Katsuhiko|Suemoto, Yuko|Kirkner, Gregory J|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 18204436
Journal: Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title: WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Liu, Zhiqian|Yamamoto, Hiroyuki|Loda, Massimo|Fuchs, Charles S|Ogino, Shuji
PMID: 18084250
Journal: Neoplasia. 2008 Jun;10(6):534-41.
Title: PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author: Nosho, Katsuhiko|Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Zepf, Dimity|Yan, Liying|Longtine, Janina A|Fuchs, Charles S|Ogino, Shuji
PMID: 18516290
Journal: Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title: DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Baba, Yoshifumi|Kirkner, Gregory J|Chen, Li|Gokhale, Sumita|Hazra, Aditi|Spiegelman, Donna|Giovannucci, Edward L|Jaenisch, Rudolf|Fuchs, Charles S|Ogino, Shuji
PMID: 19470733
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: J Interferon Cytokine Res. 2009 Dec;29(12):809-16.
Title: Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells.
Author: Liu, Xiao Hong|Xu, Shuang Bing|Yuan, Jia|Li, Ben Hui|Zhang, Yan|Yuan, Qin|Li, Pin Dong|Li, Feng|Zhang, Wen Jie
PMID: 19929568
Journal: Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title: Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Meyerhardt, Jeffrey A|Baba, Yoshifumi|Shima, Kaori|Glickman, Jonathan N|Ferrone, Cristina R|Mino-Kenudson, Mari|Tanaka, Noriko|Dranoff, Glenn|Giovannucci, Edward L|Fuchs, Charles S
PMID: 19825961
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title: Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author: Kure, Shoko|Nosho, Katsuhiko|Baba, Yoshifumi|Irahara, Natsumi|Shima, Kaori|Ng, Kimmie|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19789368
Journal: Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title: A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author: Nosho, Katsuhiko|Kure, Shoko|Irahara, Natsumi|Shima, Kaori|Baba, Yoshifumi|Spiegelman, Donna|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19686742
Journal: J Cancer Res Clin Oncol. 2009 Dec;135(12):1791-8.
Title: DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells.
Author: Xu, Shuang Bing|Liu, Xiao Hong|Li, Ben Hui|Zhang, Yan|Yuan, Jia|Yuan, Qin|Li, Pin Dong|Yang, Xian Zi|Li, Feng|Zhang, Wen Jie
PMID: 19551406
Journal: Cancer Sci. 2009 Apr;100(4):730-6.
Title: Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation.
Author: Hashimoto, Masayuki|Ayada, Toranoshin|Kinjyo, Ichiko|Hiwatashi, Kiyokazu|Yoshida, Hideyuki|Okada, Yasunori|Kobayashi, Takashi|Yoshimura, Akihiko
PMID: 19469017
Journal: Mod Pathol. 2009 Jul;22(7):922-32.
Title: SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Firestein, Ron|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Hazra, Aditi|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19430421
Journal: Neoplasia. 2009 Jan;11(1):87-95.
Title: JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author: Nosho, Katsuhiko|Shima, Kaori|Kure, Shoko|Irahara, Natsumi|Baba, Yoshifumi|Chen, Li|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 19107235
Journal: Gut. 2009 Jan;58(1):90-6.
Title: CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author: Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Kawasaki, Takako|Meyerhardt, Jeffrey A|Loda, Massimo|Giovannucci, Edward L|Fuchs, Charles S
PMID: 18832519
Journal: J Cancer Res Clin Oncol. 2009 Jan;135(1):131-40.
Title: Differential IL-4/Stat6 activities correlate with differential expression of regulatory genes SOCS-1, SHP-1, and PP2A in colon cancer cells.
Author: Yuan, Qin|Li, Pin Dong|Li, Ben Hui|Yang, Xian Zi|Xu, Shuang Bing|Liu, Xiao Hong|Zhou, Fu Xiang|Zhang, Wen Jie
PMID: 18536936
Journal: Am J Pathol. 2010 Dec;177(6):2731-40.
Title: Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author: Tanaka, Noriko|Huttenhower, Curtis|Nosho, Katsuhiko|Baba, Yoshifumi|Shima, Kaori|Quackenbush, John|Haigis, Kevin M|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21037082
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title: PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Goessling, Wolfram|Chan, Andrew T|Ng, Kimmie|Chan, Jennifer A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20200425
Journal: Gastroenterology. 2010 May;138(5):1854-62.
Title: Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency.
Author: Goel, Ajay|Xicola, Rosa M|Nguyen, Thuy-Phuong|Doyle, Brian J|Sohn, Vanessa R|Bandipalliam, Prathap|Rozek, Laura S|Reyes, Josep|Cordero, Carmen|Balaguer, Francesc|Castells, Antoni|Jover, Rodrigo|Andreu, Montserrat|Syngal, Sapna|Boland, C Richard|Llor, Xavi
PMID: 20102720
Journal: Cancer Epidemiol. 2010 Jun;34(3):338-44.
Title: Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype.
Author: Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Misiak, Blazej|Gil, Justyna|Laczmanska, Izabela|Grzebieniak, Zygmunt|Sebzda, Tadeusz|Smigiel, Robert|Stembalska, Agnieszka|Sasiadek, Maria M
PMID: 20381446
Journal: Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author: Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20473920
Journal: Cancer Causes Control. 2011 Feb;22(2):301-9.
Title: MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author: Shima, Kaori|Morikawa, Teppei|Baba, Yoshifumi|Nosho, Katsuhiko|Suzuki, Maiko|Yamauchi, Mai|Hayashi, Marika|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21140203
Journal: Gastroenterology. 2011 Apr;140(4):1174-81.
Title: 5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer.
Author: Jover, Rodrigo|Nguyen, Thuy-Phuong|Perez-Carbonell, Lucia|Zapater, Pedro|Paya, Artemio|Alenda, Cristina|Rojas, Estefania|Cubiella, Joaquin|Balaguer, Francesc|Morillas, Juan D|Clofent, Juan|Bujanda, Luis|Rene, Josep M|Bessa, Xavier|Xicola, Rosa M|Nicolas-P
PMID: 21185836
Journal: Tumour Biol. 2011 Aug;32(4):653-9.
Title: Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.
Author: Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Kielan, Wojciech|Sasiadek, Maria Malgorzata
PMID: 21625944
Journal: PLoS One. 2011;6(6):e21102.
Title: B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author: Schernhammer, Eva S|Giovannucci, Edward|Baba, Yoshifumi|Fuchs, Charles S|Ogino, Shuji
PMID: 21738611
Journal: Gastroenterology. 2011 Nov;141(5):1749-61.e1.
Title: Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors.
Author: Bakirtzi, Kyriaki|Hatziapostolou, Maria|Karagiannides, Iordanes|Polytarchou, Christos|Jaeger, Savina|Iliopoulos, Dimitrios|Pothoulakis, Charalabos
PMID: 21806946
Journal: Surgery. 2012 Apr;151(4):564-70.
Title: CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer.
Author: Jo, Peter|Jung, Klaus|Grade, Marian|Conradi, Lena-Christin|Wolff, Hendrik A|Kitz, Julia|Becker, Heinz|Ruschoff, Josef|Hartmann, Arndt|Beissbarth, Tim|Muller-Dornieden, Annegret|Ghadimi, Michael|Schneider-Stock, Regine|Gaedcke, Jochen
PMID: 22001634
Journal: Scand J Clin Lab Invest. 2012 Dec;72(8):593-601.
Title: Human monocyte responses to lipopolysaccharide and 9-cis retinoic acid after laparoscopic surgery for colon cancer.
Author: Kolseth, Ingrid B M|Forland, Dag T|Risoe, Petter K|Flood-Kjeldsen, Signe|Agren, Joanna|Reseland, Janne E|Lyngstadaas, Staale P|Johnson, Egil|Dahle, Maria K
PMID: 23094762
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15;303(10):G1087-95.
Title: Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1.
Author: McClellan, Jamie L|Davis, J Mark|Steiner, Jennifer L|Enos, Reilly T|Jung, Seung H|Carson, James A|Pena, Maria M|Carnevale, Kevin A|Berger, Franklin G|Murphy, E Angela
PMID: 23019193
Journal: Dig Dis Sci. 2012 May;57(5):1261-70.
Title: Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7.
Author: Kaji, Eisuke|Uraoka, Toshio|Kato, Jun|Hiraoka, Sakiko|Suzuki, Hideyuki|Akita, Mitsuhiro|Saito, Shunsuke|Tanaka, Takehiro|Ohara, Nobuya|Yamamoto, Kazuhide
PMID: 22173745
Journal: Int J Surg Pathol. 2012 Apr;20(2):185-90.
Title: Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Author: Remo, Andrea|Zanella, Caterina|Molinari, Enrico|Talamini, Alberto|Tollini, Filippo|Piacentini, Paolo|Battaglia, Paolo|Baritono, Elisabetta|Bonetti, Andrea|Lanza, Franco|Fasolin, Antonio|Manfrin, Erminia|Vendraminelli, Roberto
PMID: 21791485
Journal: Mol Carcinog. 2012 Feb;51(2):174-84.
Title: Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells.
Author: Xiong, Hua|Du, Wan|Zhang, Yan-Jie|Hong, Jie|Su, Wen-Yu|Tang, Jie-Ting|Wang, Ying-Chao|Lu, Rong|Fang, Jing-Yuan
PMID: 21520296
Journal: Mol Carcinog. 2013 Feb;52(2):155-66.
Title: JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K
PMID: 22121102
Journal: Int J Cancer. 2013 May 1;132(9):2209-16.
Title: Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Author: Han, Sae-Won|Lee, Hyun-Jung|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Park, Jae-Gahb|Kang, Gyeong Hoon|Kim, Tae-You
PMID: 23034738
Journal: Carcinogenesis. 2013 Jul;34(7):1567-74.
Title: Inhibitory role of Gas6 in intestinal tumorigenesis.
Author: Akitake-Kawano, Reiko|Seno, Hiroshi|Nakatsuji, Masato|Kimura, Yuto|Nakanishi, Yuki|Yoshioka, Takuto|Kanda, Keitaro|Kawada, Mayumi|Kawada, Kenji|Sakai, Yoshiharu|Chiba, Tsutomu
PMID: 23430954
Journal: PLoS One. 2013 Oct 8;8(10):e76865.
Title: Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice.
Author: Pussila, Marjaana|Sarantaus, Laura|Dermadi Bebek, Denis|Valo, Satu|Reyhani, Nima|Ollila, Saara|Paivarinta, Essi|Peltomaki, Paivi|Mutanen, Marja|Nystrom, Minna
PMID: 24204690
Journal: Asian Pac J Cancer Prev. 2013;14(12):7583-6.
Title: The SOCS-1 -1478CA/del polymorphism is not associated with colorectal cancer or age at onset in Turkish subjects.
Author: Hartavi, Mustafa|Kurt, Ender|Oral, Barbaros|Olmez, Omer Fatih|Cubukcu, Erdem|Deligonul, Adem|Avci, Nilufer|Manavoglu, Osman
PMID: 24460337
Journal: PLoS One. 2014 Jan 21;9(1):e86657.
Title: Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels.
Author: Berg, Marianne|Hagland, Hanne R|Soreide, Kjetil
PMID: 24466191
Journal: Asian Pac J Cancer Prev. 2014;15(19):8469-74.
Title: Lack of prognostic significance of SOCS-1 expression in colorectal adenocarcinomas.
Author: Ayyildiz, Talat|Dolar, Enver|Adim, Saduman Balaban|Eminler, Ahmet Tarik|Yerci, Omer
PMID: 25339048
Journal: Mol Oncol. 2014 Jul;8(5):942-55.
Title: Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells.
Author: David, Muriel|Naudin, Cecile|Letourneur, Martine|Polrot, Melanie|Renoir, Jack-Michel|Lazar, Vladimir|Dessen, Philippe|Roche, Serge|Bertoglio, Jacques|Pierre, Josiane
PMID: 24726456
Journal: Gastroenterology. 2014 Sep;147(3):637-45.
Title: CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.
Author: Shiovitz, Stacey|Bertagnolli, Monica M|Renfro, Lindsay A|Nam, Eunmi|Foster, Nathan R|Dzieciatkowski, Slavomir|Luo, Yanxin|Lao, Victoria Valinluck|Monnat, Raymond J Jr|Emond, Mary J|Maizels, Nancy|Niedzwiecki, Donna|Goldberg, Richard M|Saltz, Leonard B|Ven
PMID: 24859205
Journal: Gut Liver. 2015 Mar;9(2):202-7.
Title: The role of the CpG island methylator phenotype on survival outcome in colon cancer.
Author: Kang, Ki Joo|Min, Byung Hoon|Ryu, Kyung Ju|Kim, Kyoung Mee|Chang, Dong Kyung|Kim, Jae J|Rhee, Jong Chul|Kim, Young Ho
PMID: 25167802
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015.
Title: Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Author: Kim, Jung Ho|Cho, Nam-Yun|Bae, Jeong Mo|Kim, Kyung-Ju|Rhee, Ye-Young|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 25973084
Journal: Sci Rep. 2015 Sep 22;5:14301.
Title: Tumour-promoting role of SOCS1 in colorectal cancer cells.
Author: Tobelaim, William S|Beaurivage, Claudia|Champagne, Audrey|Pomerleau, Veronique|Simoneau, Aline|Chababi, Walid|Yeganeh, Mehdi|Thibault, Philippe|Klinck, Roscoe|Carrier, Julie C|Ferbeyre, Gerardo|Ilangumaran, Subburaj|Saucier, Caroline
PMID: 26391193
Journal: Oncoimmunology. 2016 Aug 3;5(9):e1211219.
Title: Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis.
Author: Jiang, Xingwei|Zhou, Tingting|Xiao, Yan|Yu, Jiahui|Dou, Shuaijie|Chen, Guojiang|Wang, Renxi|Xiao, He|Hou, Chunmei|Wang, Wei|Shi, Qingzhu|Feng, Jiannan|Ma, Yuanfang|Shen, Beifen|Li, Yan|Han, Gencheng
PMID: 27757304
Journal: Oncotarget. 2016 Sep 20;7(38):62559-62571.
Title: Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation.
Author: Jung, Sung-Hoon|Kim, Su-Min|Lee, Choong-Eun
PMID: 27613835
Journal: Oncotarget. 2016 Mar 22;7(12):14095-111.
Title: Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway.
Author: Kim, Jung Ho|Bae, Jeong Mo|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 26883113
Journal: Clin Colorectal Cancer. 2016 Jun;15(2):164-9.
Title: Evaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin.
Author: Cohen, Stacey A|Wu, Chen|Yu, Ming|Gourgioti, Georgia|Wirtz, Ralph|Raptou, Georgia|Gkakou, Chryssa|Kotoula, Vassiliki|Pentheroudakis, George|Papaxoinis, George|Karavasilis, Vasilios|Pectasides, Dimitrios|Kalogeras, Konstantine T|Fountzilas, George|Grady, W
PMID: 26702772
Journal: Clin Epigenetics. 2017 May 2;9:46.
Title: The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases.
Author: Cohen, Stacey A|Yu, Ming|Baker, Kelsey|Redman, Mary|Wu, Chen|Heinzerling, Tai J|Wirtz, Ralph M|Charalambous, Elpida|Pentheroudakis, George|Kotoula, Vassiliki|Kalogeras, Konstantine T|Fountzilas, George|Grady, William M
PMID: 28469732
Journal: Int J Cancer. 2017 Sep 1;141(5):967-976.
Title: CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers.
Author: Vedeld, Hege Marie|Merok, Marianne|Jeanmougin, Marine|Danielsen, Stine A|Honne, Hilde|Presthus, Gro Kummeneje|Svindland, Aud|Sjo, Ole H|Hektoen, Merete|Eknaes, Mette|Nesbakken, Arild|Lothe, Ragnhild A|Lind, Guro E
PMID: 28542846
Journal: Oncotarget. 2017 Jul 25;8(30):49807-49823.
Title: Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway.
Author: Ren, Dong|Lin, Bihua|Zhang, Xin|Peng, Yao|Ye, Ziyu|Ma, Yan|Liang, Yangfang|Cao, Longbin|Li, Xiangyong|Li, Ronggang|Sun, Lixia|Liu, Qiongru|Wu, Jinhua|Zhou, Keyuan|Zeng, Jincheng
PMID: 28591704
Journal: JCI Insight. 2017 Sep 21;2(18). pii: 91828.
Title: ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis.
Author: Yin, Mingzhu|Zhou, Huanjiao Jenny|Zhang, Jiqin|Lin, Caixia|Li, Hongmei|Li, Xia|Li, Yonghao|Zhang, Haifeng|Breckenridge, David G|Ji, Weidong|Min, Wang
PMID: 28931753
Journal: Hum Pathol. 2018 Apr;74:54-63.
Title: Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain?
Author: Huhns, Maja|Krohn, Saskia|Murua Escobar, Hugo|Prall, Friedrich
PMID: 29307628
Journal: Int J Cancer. 2018 Aug 15;143(4):886-896.
Title: Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.
Author: Pan, Pan|Oshima, Kiyoko|Huang, Yi-Wen|Agle, Kimberle A|Drobyski, William R|Chen, Xiao|Zhang, Jianying|Yearsley, Martha M|Yu, Jianhua|Wang, Li-Shu
PMID: 29524208
Journal: Clin Cancer Res. 2018 Oct 1;24(19):4745-4753.
Title: Prognostic Value of Methylator Phenotype in Stage III Colon Cancer Treated with Oxaliplatin-based Adjuvant Chemotherapy.
Author: Gallois, Claire|Taieb, Julien|Le Corre, Delphine|Le Malicot, Karine|Tabernero, Josep|Mulot, Claire|Seitz, Jean-Francois|Aparicio, Thomas|Folprecht, Gunnar|Lepage, Come|Mini, Enrico|Van Laethem, Jean-Luc|Emile, Jean-Francois|Laurent-Puig, Pierre
PMID: 29921730
Journal: Sci Rep. 2018 Jun 21;8(1):9470.
Title: Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans.
Author: Busch, Evan L|Galanko, Joseph A|Sandler, Robert S|Goel, Ajay|Keku, Temitope O
PMID: 29930328