Primary Site >> Colorectal Cancer
Gene >> SOCS1
| 1. | |||||||||||
| Journal: | J Gastroenterol. 2004;39(2):120-4. | ||||||||||
| Title: | Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients. | ||||||||||
| Author: | Fujitake, Shinichi|Hibi, Kenji|Okochi, Osamu|Kodera, Yasuhiro|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa | ||||||||||
| PMID: | 15074307 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncol Rep. 2004 Feb;11(2):341-8. | ||||||||||
| Title: | Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features. | ||||||||||
| Author: | Lin, Shyr-Yi|Yeh, Kun-Tu|Chen, Willian Tzu-Liang|Chen, Hung-Chang|Chen, Shou-Tung|Chiou, Hung-Yi|Chang, Jan-Gowth | ||||||||||
| PMID: | 14719065 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2004 Dec 10;112(5):846-53. | ||||||||||
| Title: | Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia. | ||||||||||
| Author: | Bai, Alfa H C|Tong, Joanna H M|To, Ka-Fai|Chan, Michael W Y|Man, Ellen P S|Lo, Kwok-Wai|Lee, Janet F Y|Sung, Joseph J Y|Leung, Wai K | ||||||||||
| PMID: | 15386372 | ||||||||||
| 4. | |||||||||||
| Journal: | J Invest Dermatol. 2006 Feb;126(2):422-31. | ||||||||||
| Title: | Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma. | ||||||||||
| Author: | Marini, Alessandra|Mirmohammadsadegh, Alireza|Nambiar, Sandeep|Gustrau, Annett|Ruzicka, Thomas|Hengge, Ulrich R | ||||||||||
| PMID: | 16374457 | ||||||||||
| 5. | |||||||||||
| Journal: | J Exp Med. 2006 Jun 12;203(6):1391-7. Epub 2006 May 22. | ||||||||||
| Title: | IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. | ||||||||||
| Author: | Hanada, Toshikatsu|Kobayashi, Takashi|Chinen, Takatoshi|Saeki, Kazuko|Takaki, Hiromi|Koga, Keiko|Minoda, Yasumasa|Sanada, Takahito|Yoshioka, Tomoko|Mimata, Hiromitsu|Kato, Seiya|Yoshimura, Akihiko | ||||||||||
| PMID: | 16717119 | ||||||||||
| 6. | |||||||||||
| Journal: | Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19. | ||||||||||
| Title: | Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S | ||||||||||
| PMID: | 17239930 | ||||||||||
| 7. | |||||||||||
| Journal: | Neoplasia. 2007 Dec;9(12):1091-8. | ||||||||||
| Title: | IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53. | ||||||||||
| Author: | Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 18084616 | ||||||||||
| 8. | |||||||||||
| Journal: | Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6. | ||||||||||
| Title: | Promoter methylation status of multiple genes in uveal melanoma. | ||||||||||
| Author: | Merhavi, Efrat|Cohen, Yoram|Avraham, Bat Chen R|Frenkel, Shahar|Chowers, Itay|Pe'er, Jacob|Goldenberg-Cohen, Nitza | ||||||||||
| PMID: | 17898258 | ||||||||||
| 9. | |||||||||||
| Journal: | Neoplasia. 2007 Jul;9(7):569-77. | ||||||||||
| Title: | Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer. | ||||||||||
| Author: | Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Dehari, Reiko|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 17710160 | ||||||||||
| 10. | |||||||||||
| Journal: | Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9. | ||||||||||
| Title: | MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer. | ||||||||||
| Author: | Ogino, Shuji|Hazra, Aditi|Tranah, Gregory J|Kirkner, Gregory J|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Meyerhardt, Jeffrey A|Hunter, David J|Fuchs, Charles S | ||||||||||
| PMID: | 17621591 | ||||||||||
| 11. | |||||||||||
| Journal: | J Mol Diagn. 2007 Jul;9(3):305-14. | ||||||||||
| Title: | Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Kraft, Peter|Loda, Massimo|Fuchs, Charles S | ||||||||||
| PMID: | 17591929 | ||||||||||
| 12. | |||||||||||
| Journal: | BMC Cancer. 2007 May 2;7:72. | ||||||||||
| Title: | 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Ohnishi, Mutsuko|Fuchs, Charles S | ||||||||||
| PMID: | 17474983 | ||||||||||
| 13. | |||||||||||
| Journal: | Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20. | ||||||||||
| Title: | CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma. | ||||||||||
| Author: | Ogino, Shuji|Meyerhardt, Jeffrey A|Kawasaki, Takako|Clark, Jeffrey W|Ryan, David P|Kulke, Matthew H|Enzinger, Peter C|Wolpin, Brian M|Loda, Massimo|Fuchs, Charles S | ||||||||||
| PMID: | 17372756 | ||||||||||
| 14. | |||||||||||
| Journal: | Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12. | ||||||||||
| Title: | Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S | ||||||||||
| PMID: | 17350669 | ||||||||||
| 15. | |||||||||||
| Journal: | Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5. | ||||||||||
| Title: | Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Suemoto, Yuko|Meyerhardt, Jeffrey A|Fuchs, Charles S | ||||||||||
| PMID: | 17339237 | ||||||||||
| 16. | |||||||||||
| Journal: | Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31. | ||||||||||
| Title: | TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S | ||||||||||
| PMID: | 17270239 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2008;3(11):e3698. | ||||||||||
| Title: | Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. | ||||||||||
| Author: | Nosho, Katsuhiko|Irahara, Natsumi|Shima, Kaori|Kure, Shoko|Kirkner, Gregory J|Schernhammer, Eva S|Hazra, Aditi|Hunter, David J|Quackenbush, John|Spiegelman, Donna|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19002263 | ||||||||||
| 18. | |||||||||||
| Journal: | Histopathology. 2008 Nov;53(5):588-98. | ||||||||||
| Title: | Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype. | ||||||||||
| Author: | Nosho, K|Kawasaki, T|Chan, A T|Ohnishi, M|Suemoto, Y|Kirkner, G J|Fuchs, C S|Ogino, S | ||||||||||
| PMID: | 18983468 | ||||||||||
| 19. | |||||||||||
| Journal: | Arch Pathol Lab Med. 2008 Oct;132(10):1657-65. | ||||||||||
| Title: | CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels. | ||||||||||
| Author: | Lee, Sun|Cho, Nam-Yun|Yoo, Eun Joo|Kim, Jung Ho|Kang, Gyeong Hoon | ||||||||||
| PMID: | 18834226 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Sci. 2008 Aug;99(8):1650-5. | ||||||||||
| Title: | Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells. | ||||||||||
| Author: | Takahashi, Yuki|Kaneda, Haruka|Takasuka, Nana|Hattori, Kayoko|Nishikawa, Makiya|Watanabe, Yoshihiko|Takakura, Yoshinobu | ||||||||||
| PMID: | 18754879 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1774-80. | ||||||||||
| Title: | Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype. | ||||||||||
| Author: | English, Dallas R|Young, Joanne P|Simpson, Julie A|Jenkins, Mark A|Southey, Melissa C|Walsh, Michael D|Buchanan, Daniel D|Barker, Melissa A|Haydon, Andrew M|Royce, Simon G|Roberts, Aedan|Parry, Susan|Hopper, John L|Jass, Jeremy J|Giles, Graham G | ||||||||||
| PMID: | 18628431 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Cancer. 2008 Jun 15;122(12):2767-73. | ||||||||||
| Title: | LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Ogino, Shuji|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S | ||||||||||
| PMID: | 18366060 | ||||||||||
| 23. | |||||||||||
| Journal: | Mod Pathol. 2008 Mar;21(3):245-55. | ||||||||||
| Title: | CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci. | ||||||||||
| Author: | Kawasaki, Takako|Ohnishi, Mutsuko|Nosho, Katsuhiko|Suemoto, Yuko|Kirkner, Gregory J|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 18204436 | ||||||||||
| 24. | |||||||||||
| Journal: | Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14. | ||||||||||
| Title: | WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Liu, Zhiqian|Yamamoto, Hiroyuki|Loda, Massimo|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 18084250 | ||||||||||
| 25. | |||||||||||
| Journal: | Neoplasia. 2008 Jun;10(6):534-41. | ||||||||||
| Title: | PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations. | ||||||||||
| Author: | Nosho, Katsuhiko|Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Zepf, Dimity|Yan, Liying|Longtine, Janina A|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 18516290 | ||||||||||
| 26. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Jun 1;15(11):3663-71. | ||||||||||
| Title: | DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Baba, Yoshifumi|Kirkner, Gregory J|Chen, Li|Gokhale, Sumita|Hazra, Aditi|Spiegelman, Donna|Giovannucci, Edward L|Jaenisch, Rudolf|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19470733 | ||||||||||
| 27. | |||||||||||
| Journal: | J Cell Mol Med. 2009 Sep;13(9B):3668-79. | ||||||||||
| Title: | Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. | ||||||||||
| Author: | Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan | ||||||||||
| PMID: | 20196786 | ||||||||||
| 28. | |||||||||||
| Journal: | J Interferon Cytokine Res. 2009 Dec;29(12):809-16. | ||||||||||
| Title: | Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. | ||||||||||
| Author: | Liu, Xiao Hong|Xu, Shuang Bing|Yuan, Jia|Li, Ben Hui|Zhang, Yan|Yuan, Qin|Li, Pin Dong|Li, Feng|Zhang, Wen Jie | ||||||||||
| PMID: | 19929568 | ||||||||||
| 29. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Oct 15;15(20):6412-20. | ||||||||||
| Title: | Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype. | ||||||||||
| Author: | Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Meyerhardt, Jeffrey A|Baba, Yoshifumi|Shima, Kaori|Glickman, Jonathan N|Ferrone, Cristina R|Mino-Kenudson, Mari|Tanaka, Noriko|Dranoff, Glenn|Giovannucci, Edward L|Fuchs, Charles S | ||||||||||
| PMID: | 19825961 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72. | ||||||||||
| Title: | Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer. | ||||||||||
| Author: | Kure, Shoko|Nosho, Katsuhiko|Baba, Yoshifumi|Irahara, Natsumi|Shima, Kaori|Ng, Kimmie|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19789368 | ||||||||||
| 31. | |||||||||||
| Journal: | Gastroenterology. 2009 Nov;137(5):1609-20.e1-3. | ||||||||||
| Title: | A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers. | ||||||||||
| Author: | Nosho, Katsuhiko|Kure, Shoko|Irahara, Natsumi|Shima, Kaori|Baba, Yoshifumi|Spiegelman, Donna|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19686742 | ||||||||||
| 32. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2009 Dec;135(12):1791-8. | ||||||||||
| Title: | DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. | ||||||||||
| Author: | Xu, Shuang Bing|Liu, Xiao Hong|Li, Ben Hui|Zhang, Yan|Yuan, Jia|Yuan, Qin|Li, Pin Dong|Yang, Xian Zi|Li, Feng|Zhang, Wen Jie | ||||||||||
| PMID: | 19551406 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Sci. 2009 Apr;100(4):730-6. | ||||||||||
| Title: | Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation. | ||||||||||
| Author: | Hashimoto, Masayuki|Ayada, Toranoshin|Kinjyo, Ichiko|Hiwatashi, Kiyokazu|Yoshida, Hideyuki|Okada, Yasunori|Kobayashi, Takashi|Yoshimura, Akihiko | ||||||||||
| PMID: | 19469017 | ||||||||||
| 34. | |||||||||||
| Journal: | Mod Pathol. 2009 Jul;22(7):922-32. | ||||||||||
| Title: | SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Firestein, Ron|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Hazra, Aditi|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19430421 | ||||||||||
| 35. | |||||||||||
| Journal: | Neoplasia. 2009 Jan;11(1):87-95. | ||||||||||
| Title: | JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Kure, Shoko|Irahara, Natsumi|Baba, Yoshifumi|Chen, Li|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19107235 | ||||||||||
| 36. | |||||||||||
| Journal: | Gut. 2009 Jan;58(1):90-6. | ||||||||||
| Title: | CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. | ||||||||||
| Author: | Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Kawasaki, Takako|Meyerhardt, Jeffrey A|Loda, Massimo|Giovannucci, Edward L|Fuchs, Charles S | ||||||||||
| PMID: | 18832519 | ||||||||||
| 37. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2009 Jan;135(1):131-40. | ||||||||||
| Title: | Differential IL-4/Stat6 activities correlate with differential expression of regulatory genes SOCS-1, SHP-1, and PP2A in colon cancer cells. | ||||||||||
| Author: | Yuan, Qin|Li, Pin Dong|Li, Ben Hui|Yang, Xian Zi|Xu, Shuang Bing|Liu, Xiao Hong|Zhou, Fu Xiang|Zhang, Wen Jie | ||||||||||
| PMID: | 18536936 | ||||||||||
| 38. | |||||||||||
| Journal: | Am J Pathol. 2010 Dec;177(6):2731-40. | ||||||||||
| Title: | Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer. | ||||||||||
| Author: | Tanaka, Noriko|Huttenhower, Curtis|Nosho, Katsuhiko|Baba, Yoshifumi|Shima, Kaori|Quackenbush, John|Haigis, Kevin M|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 21037082 | ||||||||||
| 39. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31. | ||||||||||
| Title: | PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. | ||||||||||
| Author: | Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Goessling, Wolfram|Chan, Andrew T|Ng, Kimmie|Chan, Jennifer A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 20200425 | ||||||||||
| 40. | |||||||||||
| Journal: | Gastroenterology. 2010 May;138(5):1854-62. | ||||||||||
| Title: | Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. | ||||||||||
| Author: | Goel, Ajay|Xicola, Rosa M|Nguyen, Thuy-Phuong|Doyle, Brian J|Sohn, Vanessa R|Bandipalliam, Prathap|Rozek, Laura S|Reyes, Josep|Cordero, Carmen|Balaguer, Francesc|Castells, Antoni|Jover, Rodrigo|Andreu, Montserrat|Syngal, Sapna|Boland, C Richard|Llor, Xavi | ||||||||||
| PMID: | 20102720 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Epidemiol. 2010 Jun;34(3):338-44. | ||||||||||
| Title: | Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype. | ||||||||||
| Author: | Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Misiak, Blazej|Gil, Justyna|Laczmanska, Izabela|Grzebieniak, Zygmunt|Sebzda, Tadeusz|Smigiel, Robert|Stembalska, Agnieszka|Sasiadek, Maria M | ||||||||||
| PMID: | 20381446 | ||||||||||
| 42. | |||||||||||
| Journal: | Int J Cancer. 2011 Mar 1;128(5):1080-94. | ||||||||||
| Title: | Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review. | ||||||||||
| Author: | Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 20473920 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Causes Control. 2011 Feb;22(2):301-9. | ||||||||||
| Title: | MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers. | ||||||||||
| Author: | Shima, Kaori|Morikawa, Teppei|Baba, Yoshifumi|Nosho, Katsuhiko|Suzuki, Maiko|Yamauchi, Mai|Hayashi, Marika|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 21140203 | ||||||||||
| 44. | |||||||||||
| Journal: | Gastroenterology. 2011 Apr;140(4):1174-81. | ||||||||||
| Title: | 5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer. | ||||||||||
| Author: | Jover, Rodrigo|Nguyen, Thuy-Phuong|Perez-Carbonell, Lucia|Zapater, Pedro|Paya, Artemio|Alenda, Cristina|Rojas, Estefania|Cubiella, Joaquin|Balaguer, Francesc|Morillas, Juan D|Clofent, Juan|Bujanda, Luis|Rene, Josep M|Bessa, Xavier|Xicola, Rosa M|Nicolas-P | ||||||||||
| PMID: | 21185836 | ||||||||||
| 45. | |||||||||||
| Journal: | Tumour Biol. 2011 Aug;32(4):653-9. | ||||||||||
| Title: | Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype. | ||||||||||
| Author: | Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Kielan, Wojciech|Sasiadek, Maria Malgorzata | ||||||||||
| PMID: | 21625944 | ||||||||||
| 46. | |||||||||||
| Journal: | PLoS One. 2011;6(6):e21102. | ||||||||||
| Title: | B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP). | ||||||||||
| Author: | Schernhammer, Eva S|Giovannucci, Edward|Baba, Yoshifumi|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 21738611 | ||||||||||
| 47. | |||||||||||
| Journal: | Gastroenterology. 2011 Nov;141(5):1749-61.e1. | ||||||||||
| Title: | Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors. | ||||||||||
| Author: | Bakirtzi, Kyriaki|Hatziapostolou, Maria|Karagiannides, Iordanes|Polytarchou, Christos|Jaeger, Savina|Iliopoulos, Dimitrios|Pothoulakis, Charalabos | ||||||||||
| PMID: | 21806946 | ||||||||||
| 48. | |||||||||||
| Journal: | Surgery. 2012 Apr;151(4):564-70. | ||||||||||
| Title: | CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer. | ||||||||||
| Author: | Jo, Peter|Jung, Klaus|Grade, Marian|Conradi, Lena-Christin|Wolff, Hendrik A|Kitz, Julia|Becker, Heinz|Ruschoff, Josef|Hartmann, Arndt|Beissbarth, Tim|Muller-Dornieden, Annegret|Ghadimi, Michael|Schneider-Stock, Regine|Gaedcke, Jochen | ||||||||||
| PMID: | 22001634 | ||||||||||
| 49. | |||||||||||
| Journal: | Scand J Clin Lab Invest. 2012 Dec;72(8):593-601. | ||||||||||
| Title: | Human monocyte responses to lipopolysaccharide and 9-cis retinoic acid after laparoscopic surgery for colon cancer. | ||||||||||
| Author: | Kolseth, Ingrid B M|Forland, Dag T|Risoe, Petter K|Flood-Kjeldsen, Signe|Agren, Joanna|Reseland, Janne E|Lyngstadaas, Staale P|Johnson, Egil|Dahle, Maria K | ||||||||||
| PMID: | 23094762 | ||||||||||
| 50. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15;303(10):G1087-95. | ||||||||||
| Title: | Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1. | ||||||||||
| Author: | McClellan, Jamie L|Davis, J Mark|Steiner, Jennifer L|Enos, Reilly T|Jung, Seung H|Carson, James A|Pena, Maria M|Carnevale, Kevin A|Berger, Franklin G|Murphy, E Angela | ||||||||||
| PMID: | 23019193 | ||||||||||
| 51. | |||||||||||
| Journal: | Dig Dis Sci. 2012 May;57(5):1261-70. | ||||||||||
| Title: | Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7. | ||||||||||
| Author: | Kaji, Eisuke|Uraoka, Toshio|Kato, Jun|Hiraoka, Sakiko|Suzuki, Hideyuki|Akita, Mitsuhiro|Saito, Shunsuke|Tanaka, Takehiro|Ohara, Nobuya|Yamamoto, Kazuhide | ||||||||||
| PMID: | 22173745 | ||||||||||
| 52. | |||||||||||
| Journal: | Int J Surg Pathol. 2012 Apr;20(2):185-90. | ||||||||||
| Title: | Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature. | ||||||||||
| Author: | Remo, Andrea|Zanella, Caterina|Molinari, Enrico|Talamini, Alberto|Tollini, Filippo|Piacentini, Paolo|Battaglia, Paolo|Baritono, Elisabetta|Bonetti, Andrea|Lanza, Franco|Fasolin, Antonio|Manfrin, Erminia|Vendraminelli, Roberto | ||||||||||
| PMID: | 21791485 | ||||||||||
| 53. | |||||||||||
| Journal: | Mol Carcinog. 2012 Feb;51(2):174-84. | ||||||||||
| Title: | Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells. | ||||||||||
| Author: | Xiong, Hua|Du, Wan|Zhang, Yan-Jie|Hong, Jie|Su, Wen-Yu|Tang, Jie-Ting|Wang, Ying-Chao|Lu, Rong|Fang, Jing-Yuan | ||||||||||
| PMID: | 21520296 | ||||||||||
| 54. | |||||||||||
| Journal: | Mol Carcinog. 2013 Feb;52(2):155-66. | ||||||||||
| Title: | JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K | ||||||||||
| PMID: | 22121102 | ||||||||||
| 55. | |||||||||||
| Journal: | Int J Cancer. 2013 May 1;132(9):2209-16. | ||||||||||
| Title: | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer. | ||||||||||
| Author: | Han, Sae-Won|Lee, Hyun-Jung|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Park, Jae-Gahb|Kang, Gyeong Hoon|Kim, Tae-You | ||||||||||
| PMID: | 23034738 | ||||||||||
| 56. | |||||||||||
| Journal: | Carcinogenesis. 2013 Jul;34(7):1567-74. | ||||||||||
| Title: | Inhibitory role of Gas6 in intestinal tumorigenesis. | ||||||||||
| Author: | Akitake-Kawano, Reiko|Seno, Hiroshi|Nakatsuji, Masato|Kimura, Yuto|Nakanishi, Yuki|Yoshioka, Takuto|Kanda, Keitaro|Kawada, Mayumi|Kawada, Kenji|Sakai, Yoshiharu|Chiba, Tsutomu | ||||||||||
| PMID: | 23430954 | ||||||||||
| 57. | |||||||||||
| Journal: | PLoS One. 2013 Oct 8;8(10):e76865. | ||||||||||
| Title: | Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice. | ||||||||||
| Author: | Pussila, Marjaana|Sarantaus, Laura|Dermadi Bebek, Denis|Valo, Satu|Reyhani, Nima|Ollila, Saara|Paivarinta, Essi|Peltomaki, Paivi|Mutanen, Marja|Nystrom, Minna | ||||||||||
| PMID: | 24204690 | ||||||||||
| 58. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2013;14(12):7583-6. | ||||||||||
| Title: | The SOCS-1 -1478CA/del polymorphism is not associated with colorectal cancer or age at onset in Turkish subjects. | ||||||||||
| Author: | Hartavi, Mustafa|Kurt, Ender|Oral, Barbaros|Olmez, Omer Fatih|Cubukcu, Erdem|Deligonul, Adem|Avci, Nilufer|Manavoglu, Osman | ||||||||||
| PMID: | 24460337 | ||||||||||
| 59. | |||||||||||
| Journal: | PLoS One. 2014 Jan 21;9(1):e86657. | ||||||||||
| Title: | Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels. | ||||||||||
| Author: | Berg, Marianne|Hagland, Hanne R|Soreide, Kjetil | ||||||||||
| PMID: | 24466191 | ||||||||||
| 60. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(19):8469-74. | ||||||||||
| Title: | Lack of prognostic significance of SOCS-1 expression in colorectal adenocarcinomas. | ||||||||||
| Author: | Ayyildiz, Talat|Dolar, Enver|Adim, Saduman Balaban|Eminler, Ahmet Tarik|Yerci, Omer | ||||||||||
| PMID: | 25339048 | ||||||||||
| 61. | |||||||||||
| Journal: | Mol Oncol. 2014 Jul;8(5):942-55. | ||||||||||
| Title: | Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells. | ||||||||||
| Author: | David, Muriel|Naudin, Cecile|Letourneur, Martine|Polrot, Melanie|Renoir, Jack-Michel|Lazar, Vladimir|Dessen, Philippe|Roche, Serge|Bertoglio, Jacques|Pierre, Josiane | ||||||||||
| PMID: | 24726456 | ||||||||||
| 62. | |||||||||||
| Journal: | Gastroenterology. 2014 Sep;147(3):637-45. | ||||||||||
| Title: | CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. | ||||||||||
| Author: | Shiovitz, Stacey|Bertagnolli, Monica M|Renfro, Lindsay A|Nam, Eunmi|Foster, Nathan R|Dzieciatkowski, Slavomir|Luo, Yanxin|Lao, Victoria Valinluck|Monnat, Raymond J Jr|Emond, Mary J|Maizels, Nancy|Niedzwiecki, Donna|Goldberg, Richard M|Saltz, Leonard B|Ven | ||||||||||
| PMID: | 24859205 | ||||||||||
| 63. | |||||||||||
| Journal: | Gut Liver. 2015 Mar;9(2):202-7. | ||||||||||
| Title: | The role of the CpG island methylator phenotype on survival outcome in colon cancer. | ||||||||||
| Author: | Kang, Ki Joo|Min, Byung Hoon|Ryu, Kyung Ju|Kim, Kyoung Mee|Chang, Dong Kyung|Kim, Jae J|Rhee, Jong Chul|Kim, Young Ho | ||||||||||
| PMID: | 25167802 | ||||||||||
| 64. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015. | ||||||||||
| Title: | Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer. | ||||||||||
| Author: | Kim, Jung Ho|Cho, Nam-Yun|Bae, Jeong Mo|Kim, Kyung-Ju|Rhee, Ye-Young|Lee, Hye Seung|Kang, Gyeong Hoon | ||||||||||
| PMID: | 25973084 | ||||||||||
| 65. | |||||||||||
| Journal: | Sci Rep. 2015 Sep 22;5:14301. | ||||||||||
| Title: | Tumour-promoting role of SOCS1 in colorectal cancer cells. | ||||||||||
| Author: | Tobelaim, William S|Beaurivage, Claudia|Champagne, Audrey|Pomerleau, Veronique|Simoneau, Aline|Chababi, Walid|Yeganeh, Mehdi|Thibault, Philippe|Klinck, Roscoe|Carrier, Julie C|Ferbeyre, Gerardo|Ilangumaran, Subburaj|Saucier, Caroline | ||||||||||
| PMID: | 26391193 | ||||||||||
| 66. | |||||||||||
| Journal: | Oncoimmunology. 2016 Aug 3;5(9):e1211219. | ||||||||||
| Title: | Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis. | ||||||||||
| Author: | Jiang, Xingwei|Zhou, Tingting|Xiao, Yan|Yu, Jiahui|Dou, Shuaijie|Chen, Guojiang|Wang, Renxi|Xiao, He|Hou, Chunmei|Wang, Wei|Shi, Qingzhu|Feng, Jiannan|Ma, Yuanfang|Shen, Beifen|Li, Yan|Han, Gencheng | ||||||||||
| PMID: | 27757304 | ||||||||||
| 67. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 20;7(38):62559-62571. | ||||||||||
| Title: | Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation. | ||||||||||
| Author: | Jung, Sung-Hoon|Kim, Su-Min|Lee, Choong-Eun | ||||||||||
| PMID: | 27613835 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 22;7(12):14095-111. | ||||||||||
| Title: | Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway. | ||||||||||
| Author: | Kim, Jung Ho|Bae, Jeong Mo|Cho, Nam-Yun|Kang, Gyeong Hoon | ||||||||||
| PMID: | 26883113 | ||||||||||
| 69. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2016 Jun;15(2):164-9. | ||||||||||
| Title: | Evaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin. | ||||||||||
| Author: | Cohen, Stacey A|Wu, Chen|Yu, Ming|Gourgioti, Georgia|Wirtz, Ralph|Raptou, Georgia|Gkakou, Chryssa|Kotoula, Vassiliki|Pentheroudakis, George|Papaxoinis, George|Karavasilis, Vasilios|Pectasides, Dimitrios|Kalogeras, Konstantine T|Fountzilas, George|Grady, W | ||||||||||
| PMID: | 26702772 | ||||||||||
| 70. | |||||||||||
| Journal: | Clin Epigenetics. 2017 May 2;9:46. | ||||||||||
| Title: | The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases. | ||||||||||
| Author: | Cohen, Stacey A|Yu, Ming|Baker, Kelsey|Redman, Mary|Wu, Chen|Heinzerling, Tai J|Wirtz, Ralph M|Charalambous, Elpida|Pentheroudakis, George|Kotoula, Vassiliki|Kalogeras, Konstantine T|Fountzilas, George|Grady, William M | ||||||||||
| PMID: | 28469732 | ||||||||||
| 71. | |||||||||||
| Journal: | Int J Cancer. 2017 Sep 1;141(5):967-976. | ||||||||||
| Title: | CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers. | ||||||||||
| Author: | Vedeld, Hege Marie|Merok, Marianne|Jeanmougin, Marine|Danielsen, Stine A|Honne, Hilde|Presthus, Gro Kummeneje|Svindland, Aud|Sjo, Ole H|Hektoen, Merete|Eknaes, Mette|Nesbakken, Arild|Lothe, Ragnhild A|Lind, Guro E | ||||||||||
| PMID: | 28542846 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 25;8(30):49807-49823. | ||||||||||
| Title: | Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway. | ||||||||||
| Author: | Ren, Dong|Lin, Bihua|Zhang, Xin|Peng, Yao|Ye, Ziyu|Ma, Yan|Liang, Yangfang|Cao, Longbin|Li, Xiangyong|Li, Ronggang|Sun, Lixia|Liu, Qiongru|Wu, Jinhua|Zhou, Keyuan|Zeng, Jincheng | ||||||||||
| PMID: | 28591704 | ||||||||||
| 73. | |||||||||||
| Journal: | JCI Insight. 2017 Sep 21;2(18). pii: 91828. | ||||||||||
| Title: | ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis. | ||||||||||
| Author: | Yin, Mingzhu|Zhou, Huanjiao Jenny|Zhang, Jiqin|Lin, Caixia|Li, Hongmei|Li, Xia|Li, Yonghao|Zhang, Haifeng|Breckenridge, David G|Ji, Weidong|Min, Wang | ||||||||||
| PMID: | 28931753 | ||||||||||
| 74. | |||||||||||
| Journal: | Hum Pathol. 2018 Apr;74:54-63. | ||||||||||
| Title: | Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain? | ||||||||||
| Author: | Huhns, Maja|Krohn, Saskia|Murua Escobar, Hugo|Prall, Friedrich | ||||||||||
| PMID: | 29307628 | ||||||||||
| 75. | |||||||||||
| Journal: | Int J Cancer. 2018 Aug 15;143(4):886-896. | ||||||||||
| Title: | Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors. | ||||||||||
| Author: | Pan, Pan|Oshima, Kiyoko|Huang, Yi-Wen|Agle, Kimberle A|Drobyski, William R|Chen, Xiao|Zhang, Jianying|Yearsley, Martha M|Yu, Jianhua|Wang, Li-Shu | ||||||||||
| PMID: | 29524208 | ||||||||||
| 76. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Oct 1;24(19):4745-4753. | ||||||||||
| Title: | Prognostic Value of Methylator Phenotype in Stage III Colon Cancer Treated with Oxaliplatin-based Adjuvant Chemotherapy. | ||||||||||
| Author: | Gallois, Claire|Taieb, Julien|Le Corre, Delphine|Le Malicot, Karine|Tabernero, Josep|Mulot, Claire|Seitz, Jean-Francois|Aparicio, Thomas|Folprecht, Gunnar|Lepage, Come|Mini, Enrico|Van Laethem, Jean-Luc|Emile, Jean-Francois|Laurent-Puig, Pierre | ||||||||||
| PMID: | 29921730 | ||||||||||
| 77. | |||||||||||
| Journal: | Sci Rep. 2018 Jun 21;8(1):9470. | ||||||||||
| Title: | Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans. | ||||||||||
| Author: | Busch, Evan L|Galanko, Joseph A|Sandler, Robert S|Goel, Ajay|Keku, Temitope O | ||||||||||
| PMID: | 29930328 | ||||||||||