Primary Site >> Colorectal Cancer

Gene >> SNAI2

Journal: J Cell Biol. 2003 Nov 24;163(4):847-57.
Title: Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK.
Author: Conacci-Sorrell, Maralice|Simcha, Inbal|Ben-Yedidia, Tamar|Blechman, Janna|Savagner, Pierre|Ben-Ze'ev, Avri
PMID: 14623871
Journal: Br J Cancer. 2006 Jun 19;94(12):1816-22.
Title: Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.
Author: Shioiri, M|Shida, T|Koda, K|Oda, K|Seike, K|Nishimura, M|Takano, S|Miyazaki, M
PMID: 16773075
Journal: Oncogene. 2007 Apr 5;26(16):2340-52. Epub 2006 Oct 2.
Title: Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids.
Author: Vincan, E|Darcy, P K|Farrelly, C A|Faux, M C|Brabletz, T|Ramsay, R G
PMID: 17016432
Journal: Cancer Res. 2007 Mar 15;67(6):2469-79.
Title: Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells.
Author: Esufali, Susmita|Charames, George S|Pethe, Vaijayanti V|Buongiorno, Pinella|Bapat, Bharati
PMID: 17363564
Journal: Oncogene. 2008 Jan 3;27(1):107-15. Epub 2007 Jun 25.
Title: The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.
Author: Gross, I|Duluc, I|Benameur, T|Calon, A|Martin, E|Brabletz, T|Kedinger, M|Domon-Dell, C|Freund, J-N
PMID: 17599044
Journal: Clin Exp Metastasis. 2009;26(6):569-87.
Title: A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.
Author: Joyce, Tobias|Cantarella, Daniela|Isella, Claudio|Medico, Enzo|Pintzas, Alexander
PMID: 19340593
Journal: J Biol Chem. 2009 Jul 17;284(29):19613-22.
Title: MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation.
Author: Hong, Chun-Fu|Chou, Yu-Ting|Lin, Young-Sun|Wu, Cheng-Wen
PMID: 19443654
Journal: Carcinogenesis. 2009 Aug;30(8):1459-68.
Title: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.
Author: Larriba, Maria Jesus|Martin-Villar, Ester|Garcia, Jose Miguel|Pereira, Fabio|Pena, Cristina|de Herreros, Antonio Garcia|Bonilla, Felix|Munoz, Alberto
PMID: 19502595
Journal: J Clin Invest. 2009 Aug;119(8):2343-58.
Title: Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.
Author: Alvarez-Diaz, Silvia|Valle, Noelia|Garcia, Jose Miguel|Pena, Cristina|Freije, Jose M P|Quesada, Victor|Astudillo, Aurora|Bonilla, Felix|Lopez-Otin, Carlos|Munoz, Alberto
PMID: 19662683
Journal: Pancreas. 2010 Apr;39(3):332-9.
Title: Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors.
Author: Pham, Hung|Chen, Monica|Li, Aihua|King, Jonathan|Angst, Eliane|Dawson, David W|Park, Jenny|Reber, Howard A|Hines, O Joe|Eibl, Guido
PMID: 19820419
Journal: Cancer Biol Ther. 2010 Feb;9(4):295-302.
Title: Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer.
Author: Meng, Hui-Min|Zheng, Ping|Wang, Xiao-Yan|Liu, Chao|Sui, Hong-Mei|Wu, Shao-Jie|Zhou, Jun|Ding, Yan-Qing|Li, Jianming
PMID: 20026903
Journal: J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):106-9.
Title: The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression.
Author: Larriba, Maria Jesus|Bonilla, Felix|Munoz, Alberto
PMID: 20138990
Journal: J Cell Sci. 2010 Apr 15;123(Pt 8):1295-305.
Title: Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells.
Author: Roger, Laureline|Jullien, Laurent|Gire, Veronique|Roux, Pierre
PMID: 20332115
Journal: Mol Cancer Ther. 2010 May;9(5):1308-17.
Title: Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Author: Serova, Maria|Astorgues-Xerri, Lucile|Bieche, Ivan|Albert, Sebastien|Vidaud, Michel|Benhadji, Karim A|Emami, Shahin|Vidaud, Dominique|Hammel, Pascal|Theou-Anton, Nathalie|Gespach, Christian|Faivre, Sandrine|Raymond, Eric
PMID: 20406951
Journal: Oncogene. 2010 Aug 19;29(33):4658-70.
Title: Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells.
Author: Wang, Y|Ngo, V N|Marani, M|Yang, Y|Wright, G|Staudt, L M|Downward, J
PMID: 20562906
Journal: J Biol Chem. 2010 Sep 17;285(38):29434-45.
Title: Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin.
Author: Tanno, Barbara|Sesti, Fabiola|Cesi, Vincenzo|Bossi, Gianluca|Ferrari-Amorotti, Giovanna|Bussolari, Rita|Tirindelli, Donatella|Calabretta, Bruno|Raschella, Giuseppe
PMID: 20622260
Journal: Mol Cancer Res. 2011 Jan;9(1):14-24.
Title: L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers.
Author: Gavert, Nancy|Vivanti, Alessia|Hazin, John|Brabletz, Thomas|Ben-Ze'ev, Avri
PMID: 21123622
Journal: Cancer Res. 2011 Feb 15;71(4):1334-43.
Title: Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta.
Author: Al-Mulla, Fahd|Bitar, Milad S|Al-Maghrebi, May|Behbehani, Abdulla I|Al-Ali, Waleed|Rath, Oliver|Doyle, Brendan|Tan, Kit Yee|Pitt, Andrew|Kolch, Walter
PMID: 21303975
Journal: J Surg Res. 2011 Sep;170(1):56-63.
Title: Slug expression enhances tumor formation in a noninvasive rectal cancer model.
Author: Camp, E Ramsay|Findlay, Victoria J|Vaena, Silvia G|Walsh, Jarret|Lewin, David N|Turner, David P|Watson, Dennis K
PMID: 21470622
Journal: J Nanobiotechnology. 2011 Sep 19;9:40.
Title: Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
Author: Sureban, Sripathi M|May, Randal|Mondalek, Fadee G|Qu, Dongfeng|Ponnurangam, Sivapriya|Pantazis, Panayotis|Anant, Shrikant|Ramanujam, Rama P|Houchen, Courtney W
PMID: 21929751
Journal: World J Gastroenterol. 2012 Feb 21;18(7):601-8.
Title: Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.
Author: Sipos, Ferenc|Galamb, Orsolya
PMID: 22363130
Journal: Int J Colorectal Dis. 2012 Aug;27(8):1021-7.
Title: mRNA expression of adipocytokines and glucocorticoid-related genes are associated with downregulation of E-cadherin mRNA in colorectal adenocarcinomas.
Author: Storkson, Ragnhild H|Aamodt, Rolf|Vetvik, Katja Kannisto|Pietilainen, Kirsi|Bukholm, Geir|Jonsdottir, Kristin|Vollan, Hilde S|Sonerud, Tonje|Luders, Torben|Jacobsen, Morten B|Bukholm, Ida R K
PMID: 22411584
Journal: Respirology. 2012 Oct;17(7):1048-59.
Title: Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis.
Author: Sato, Mitsuo|Shames, David S|Hasegawa, Yoshinori
PMID: 22452538
Journal: Oncogene. 2013 Jan 10;32(2):180-9.
Title: TGF-beta1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells.
Author: Schafer, H|Struck, B|Feldmann, E-M|Bergmann, F|Grage-Griebenow, E|Geismann, C|Ehlers, S|Altevogt, P|Sebens, S
PMID: 22349829
Journal: Int J Cancer. 2013 Apr 1;132(7):1487-95.
Title: Insights into cancer metastasis from a clinicopathologic perspective: Epithelial-Mesenchymal Transition is not a necessary step.
Author: Chui, Michael Herman
PMID: 22833228
Journal: Surg Today. 2013 Jan;43(1):73-80.
Title: Differences in the expression of epithelial-mesenchymal transition related molecules between primary tumors and pulmonary metastatic tumors in colorectal cancer.
Author: Kouso, Hidenori|Yano, Tokujiro|Maruyama, Riichiroh|Shikada, Yasunori|Okamoto, Tatsuro|Haro, Akira|Kakeji, Yoshihiro|Maehara, Yoshihiko
PMID: 23052737
Journal: Int J Cancer. 2013 May 1;132(9):1996-2005.
Title: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer.
Author: Singh, Navneet|Liu, Guangming|Chakrabarty, Subhas
PMID: 23055106
Journal: Cancer Lett. 2013 Jan 28;328(2):278-84.
Title: A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression.
Author: Li, Zongmeng|Mou, Haiwei|Wang, Ting|Xue, Jing|Deng, Bo|Qian, Lihua|Zhou, Ye|Gong, Wanghua|Wang, Ji Ming|Wu, Guohao|Zhou, Cheng-Fu|Fang, Jing|Le, Yingying
PMID: 23059759
Journal: Biochim Biophys Acta. 2013 Mar;1830(3):2509-16.
Title: Beta-catenin signaling induces CYP1A1 expression by disrupting adherens junctions in Caco-2 human colon carcinoma cells.
Author: Kasai, Shuya|Ishigaki, Takanori|Takumi, Ryo|Kamimura, Toru|Kikuchi, Hideaki
PMID: 23174221
Journal: Int J Oncol. 2013 Feb;42(2):556-64.
Title: Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition.
Author: Tanahashi, Toshiyuki|Osada, Shinji|Yamada, Atsuko|Kato, Junko|Yawata, Kazunori|Mori, Ryutaro|Imai, Hisashi|Sasaki, Yoshiyuki|Saito, Shiro|Tanaka, Yoshihiro|Nonaka, Kenichi|Yoshida, Kazuhiro
PMID: 23229794
Journal: Tumour Biol. 2013 Apr;34(2):1189-204.
Title: MTA-1 expression is associated with metastasis and epithelial to mesenchymal transition in colorectal cancer cells.
Author: Tuncay Cagatay, Seda|Cimen, Ismail|Savas, Berna|Banerjee, Sreeparna
PMID: 23371285
Journal: PLoS One. 2013;8(2):e56664.
Title: Epithelial-mesenchymal transition (EMT) induced by TNF-alpha requires AKT/GSK-3beta-mediated stabilization of snail in colorectal cancer.
Author: Wang, Hao|Wang, Hong-Sheng|Zhou, Bin-Hua|Li, Cui-Lin|Zhang, Fan|Wang, Xian-Feng|Zhang, Ge|Bu, Xian-Zhang|Cai, Shao-Hui|Du, Jun
PMID: 23431386
Journal: Cancer Prev Res (Phila). 2013 Jun;6(6):585-93.
Title: Vitamin D receptor and retinoid X receptor alpha status and vitamin D insufficiency in models of murine colitis.
Author: Knackstedt, Rebecca W|Moseley, Vondina R|Sun, Shaoli|Wargovich, Michael J
PMID: 23585425
Journal: Cell Oncol (Dordr). 2013 Jul;36(4):289-301.
Title: In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.
Author: Peran, Macarena|Marchal, Juan Antonio|Garcia, Maria A|Kenyon, Julian|Tosh, David
PMID: 23677639
Journal: Asian Pac J Cancer Prev. 2013;14(5):2689-98.
Title: Epithelial-mesenchymal transition and its role in the pathogenesis of colorectal cancer.
Author: Zhu, Qing-Chao|Gao, Ren-Yuan|Wu, Wen|Qin, Huan-Long
PMID: 23803016
Journal: Mol Med Rep. 2013 Oct;8(4):1055-9.
Title: Knockdown of Slug by RNAi inhibits the proliferation and invasion of HCT116 colorectal cancer cells.
Author: Qian, Jiang|Liu, Hong|Chen, Wangsheng|Wen, Kunming|Lu, Weidong|Huang, Chun|Fu, Zhongxue
PMID: 23900394
Journal: Carcinogenesis. 2013 Nov;34(11):2548-57.
Title: Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer.
Author: Toiyama, Yuji|Yasuda, Hiromi|Saigusa, Susumu|Tanaka, Koji|Inoue, Yasuhiro|Goel, Ajay|Kusunoki, Masato
PMID: 24001454
Journal: Cancer Res. 2013 Sep 15;73(18):5754-63.
Title: c-Kit is suppressed in human colon cancer tissue and contributes to L1-mediated metastasis.
Author: Gavert, Nancy|Shvab, Anna|Sheffer, Michal|Ben-Shmuel, Amir|Haase, Gal|Bakos, Eszter|Domany, Eytan|Ben-Ze'ev, Avri
PMID: 24008320
Journal: PLoS One. 2013 Sep 9;8(9):e73341.
Title: Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells.
Author: Han, Xiao-Yan|Wei, Bo|Fang, Jia-Feng|Zhang, Shi|Zhang, Fu-Cheng|Zhang, Hai-Bo|Lan, Tian-Yun|Lu, Hui-Qiong|Wei, Hong-Bo
PMID: 24039918
Journal: J Clin Endocrinol Metab. 2013 Dec;98(12):E1909-17.
Title: Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Author: Yang, Qi|Ji, Meiju|Guan, Haixia|Shi, Bingyin|Hou, Peng
PMID: 24106286
Journal: Oncogene. 2014 May 22;33(21):2758-67.
Title: Involvement of small ArfGAP1 (SMAP1), a novel Arf6-specific GTPase-activating protein, in microsatellite instability oncogenesis.
Author: Sangar, F|Schreurs, A-S|Umana-Diaz, C|Claperon, A|Desbois-Mouthon, C|Calmel, C|Mauger, O|Zaanan, A|Miquel, C|Flejou, J-F|Praz, F
PMID: 23752192
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E130-9.
Title: Slug expression inhibits calcitriol-mediated sensitivity to radiation in colorectal cancer.
Author: Findlay, Victoria J|Moretz, R Eric|Wang, Cindy|Vaena, Silvia G|Bandurraga, Savannah G|Ashenafi, Michael|Marshall, David T|Watson, Dennis K|Camp, E Ramsay
PMID: 23996472
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E151-60.
Title: Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.
Author: Suman, Suman|Kurisetty, Vittal|Das, Trinath P|Vadodkar, Aditi|Ramos, Gabriel|Lakshmanaswamy, Rajkumar|Damodaran, Chendil
PMID: 24000138
Journal: Acta Histochem. 2014 Apr;116(3):527-33.
Title: Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling.
Author: Yan, Zhaopeng|Yin, Hongzhuan|Wang, Rui|Wu, Di|Sun, Wei|Liu, Baolin|Su, Qi
PMID: 24360977
Journal: Mol Cell Biochem. 2014 May;390(1-2):19-30.
Title: MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma.
Author: Sun, Yingnan|Shen, Shourong|Liu, Xiaoping|Tang, Hailin|Wang, Zeyou|Yu, Zhibin|Li, Xiayu|Wu, Minghua
PMID: 24402783
Journal: J Cell Sci. 2014 May 1;127(Pt 9):2017-28.
Title: Angiogenic sprouting is regulated by endothelial cell expression of Slug.
Author: Welch-Reardon, Katrina M|Ehsan, Seema M|Wang, Kehui|Wu, Nan|Newman, Andrew C|Romero-Lopez, Monica|Fong, Ashley H|George, Steven C|Edwards, Robert A|Hughes, Christopher C W
PMID: 24554431
Journal: Int J Cancer. 2014 Dec 1;135(11):2537-46.
Title: Multiple effects of the special AT-rich binding protein 1 (SATB1) in colon carcinoma.
Author: Fromberg, Anja|Rabe, Michael|Aigner, Achim
PMID: 24729451
Journal: PLoS One. 2014 Apr 23;9(4):e94621.
Title: Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
Author: Sahlberg, Sara Haggblad|Spiegelberg, Diana|Glimelius, Bengt|Stenerlow, Bo|Nestor, Marika
PMID: 24760019
Journal: Mol Cancer Ther. 2014 Jul;13(7):1837-47.
Title: PIK3R3 induces epithelial-to-mesenchymal transition and promotes metastasis in colorectal cancer.
Author: Wang, Guihua|Yang, Xi|Li, Chuan|Cao, Xiaonian|Luo, Xuelai|Hu, Junbo
PMID: 24837077
Journal: Nutr Cancer. 2014;66(6):999-1008.
Title: The ethanolic extract of bark from Salix aegyptiaca L. inhibits the metastatic potential and epithelial to mesenchymal transition of colon cancer cell lines.
Author: Enayat, Shabnam|Banerjee, Sreeparna
PMID: 25175673
Journal: Oncotarget. 2014 Aug 30;5(16):6573-5.
Title: Enteric pathogens and cellular transformation: bridging the gaps.
Author: Umar, Shahid
PMID: 25216513
Journal: PLoS One. 2014 Sep 19;9(9):e107514.
Title: Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.
Author: Buhrmann, Constanze|Kraehe, Patricia|Lueders, Cora|Shayan, Parviz|Goel, Ajay|Shakibaei, Mehdi
PMID: 25238234
Journal: Mol Cancer Ther. 2014 Nov;13(11):2713-26.
Title: SNAI2 modulates colorectal cancer 5-fluorouracil sensitivity through miR145 repression.
Author: Findlay, Victoria J|Wang, Cindy|Nogueira, Lourdes M|Hurst, Katie|Quirk, Daniel|Ethier, Stephen P|Staveley O'Carroll, Kevin F|Watson, Dennis K|Camp, E Ramsay
PMID: 25249558
Journal: Biochimie. 2014 Dec;107 Pt B:310-8.
Title: Synergistic association of Notch and NFkappaB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.
Author: Gopalakrishnan, Natarajan|Sivasithamparam, Niranjali Devaraj|Devaraj, Halagowder
PMID: 25257945
Journal: Mol Oncol. 2015 Feb;9(2):335-54.
Title: SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
Author: Ronsch, Kerstin|Jagle, Sabine|Rose, Katja|Seidl, Maximilian|Baumgartner, Francis|Freihen, Vivien|Yousaf, Afsheen|Metzger, Eric|Lassmann, Silke|Schule, Roland|Zeiser, Robert|Michoel, Tom|Hecht, Andreas
PMID: 25277775
Journal: Biochem Biophys Res Commun. 2015 Jan 2;456(1):320-6.
Title: Trichostatin A, a histone deacetylase inhibitor, reverses epithelial-mesenchymal transition in colorectal cancer SW480 and prostate cancer PC3 cells.
Author: Wang, Xiaoxiong|Xu, Jun|Wang, Hao|Wu, Long|Yuan, Weiqi|Du, Jun|Cai, Shaohui
PMID: 25434997
Journal: Int J Cancer. 2015 Jul 15;137(2):491-6.
Title: Cell-surface Vimentin: A mislocalized protein for isolating csVimentin(+) CD133(-) novel stem-like hepatocellular carcinoma cells expressing EMT markers.
Author: Mitra, Abhisek|Satelli, Arun|Xia, Xueqing|Cutrera, Jeffrey|Mishra, Lopa|Li, Shulin
PMID: 25487874
Journal: Carcinogenesis. 2015 Apr;36(4):459-68.
Title: Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition.
Author: Liu, Hong|Ren, Guoping|Wang, Tingyang|Chen, Yuexia|Gong, Chaoju|Bai, Yanfeng|Wang, Bo|Qi, Hongyan|Shen, Jing|Zhu, Lijun|Qian, Cheng|Lai, Maode|Shao, Jimin
PMID: 25750173
Journal: Hum Mol Genet. 2015 Jul 1;24(13):3689-98.
Title: Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro.
Author: Senfter, Daniel|Holzner, Silvio|Kalipciyan, Maria|Staribacher, Anna|Walzl, Angelika|Huttary, Nicole|Krieger, Sigurd|Brenner, Stefan|Jager, Walter|Krupitza, Georg|Dolznig, Helmut|Mader, Robert M
PMID: 25832648
Journal: Cancer Lett. 2015 Jul 1;362(2):199-207.
Title: Restoration of the anti-proliferative and anti-migratory effects of 1,25-dihydroxyvitamin D by silibinin in vitamin D-resistant colon cancer cells.
Author: Bhatia, Vandanajay|Falzon, Miriam
PMID: 25846868
Journal: Cancer Prev Res (Phila). 2015 May;8(5):387-99.
Title: Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas.
Author: Giardina, Charles|Nakanishi, Masako|Khan, Awaad|Kuratnik, Anton|Xu, Wanli|Brenner, Bruce|Rosenberg, Daniel W
PMID: 25873367
Journal: J Cell Biochem. 2015 Nov;116(11):2517-27.
Title: Notch-1 promotes stemness and epithelial to mesenchymal transition in colorectal cancer.
Author: Fender, Alexander W|Nutter, Jennifer M|Fitzgerald, Timothy L|Bertrand, Fred E|Sigounas, George
PMID: 25914224
Journal: PLoS One. 2015 May 13;10(5):e0124612.
Title: Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial.
Author: Pentheroudakis, George|Raptou, Georgia|Kotoula, Vassiliki|Wirtz, Ralph M|Vrettou, Eleni|Karavasilis, Vasilios|Gourgioti, Georgia|Gakou, Chryssa|Syrigos, Konstantinos N|Bournakis, Evangelos|Rallis, Grigorios|Varthalitis, Ioannis|Galani, Eleni|Lazaridis, Ge
PMID: 25970543
Journal: Am J Cancer Res. 2015 Feb 15;5(3):1047-61. eCollection 2015.
Title: Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.
Author: Xie, Jing|Gao, Hui|Peng, Jianjun|Han, Yantao|Chen, Xuehong|Jiang, Qixiao|Wang, Chunbo
PMID: 26045985
Journal: Int J Clin Exp Pathol. 2015 May 1;8(5):4481-91. eCollection 2015.
Title: Up-regulation of microRNA-302a inhibited the proliferation and invasion of colorectal cancer cells by regulation of the MAPK and PI3K/Akt signaling pathways.
Author: Wei, Zhi-Jiang|Tao, Ming-Ling|Zhang, Wei|Han, Guo-Da|Zhu, Zhong-Cheng|Miao, Zhi-Gang|Li, Jian-Ye|Qiao, Zhan-Bing
PMID: 26191138
Journal: World J Gastroenterol. 2015 Sep 14;21(34):9887-99.
Title: Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancer.
Author: Kim, Jung Ho|Hwang, You-Jin|Han, Sang Hoon|Lee, Young Eun|Kim, Saerom|Kim, Yoon Jae|Cho, Jae Hee|Kwon, Kwang An|Kim, Ju Hyun|Kim, Se-Hee
PMID: 26379394
Journal: Cancers (Basel). 2015 Sep 17;7(3):1885-99.
Title: The Hedgehog Inhibitor Cyclopamine Reduces beta-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells.
Author: Qualtrough, David|Rees, Phil|Speight, Beverley|Williams, Ann C|Paraskeva, Christos
PMID: 26393651
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: Clin Colorectal Cancer. 2016 Jun;15(2):170-178.e3.
Title: Therapy-Induced Cellular Senescence Induces Epithelial-to-Mesenchymal Transition and Increases Invasiveness in Rectal Cancer.
Author: Tato-Costa, Joana|Casimiro, Sandra|Pacheco, Teresa|Pires, Ricardo|Fernandes, Afonso|Alho, Irina|Pereira, Pedro|Costa, Paulo|Castelo, Henrique Bicha|Ferreira, Joao|Costa, Luis
PMID: 26603055
Journal: Gastroenterology. 2016 Mar;150(3):659-671.e16.
Title: OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.
Author: Ye, Guo-Dong|Sun, Guang-Bin|Jiao, Peng|Chen, Chen|Liu, Qing-Feng|Huang, Xiao-Li|Zhang, Rui|Cai, Wang-Yu|Li, Sheng-Nan|Wu, Jia-Fa|Liu, Yun-Jia|Wu, Rong-Si|Xie, Yuan-Yuan|Chan, Err-Cheng|Liou, Yih-Cherng|Li, Bo-An
PMID: 26619963
Journal: Mol Biol Cell. 2016 Feb 1;27(3):535-48.
Title: By moonlighting in the nucleus, villin regulates epithelial plasticity.
Author: Patnaik, Srinivas|George, Sudeep P|Pham, Eric|Roy, Swati|Singh, Kanchan|Mariadason, John M|Khurana, Seema
PMID: 26658611
Journal: Acta Pharmacol Sin. 2016 Feb;37(2):264-75.
Title: Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2.
Author: Han, Yan-tao|Chen, Xue-hong|Gao, Hui|Ye, Jun-li|Wang, Chun-bo
PMID: 26707141
Journal: Sci Rep. 2016 Jan 11;6:18772.
Title: Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells.
Author: Morata-Tarifa, Cynthia|Jimenez, Gema|Garcia, Maria A|Entrena, Jose M|Grinan-Lison, Carmen|Aguilera, Margarita|Picon-Ruiz, Manuel|Marchal, Juan A
PMID: 26752044
Journal: Stem Cells. 2016 Apr;34(4):820-31.
Title: IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer.
Author: Yao, Chao|Su, Li|Shan, Juanjuan|Zhu, Chuanlin|Liu, Limei|Liu, Chungang|Xu, Yanmin|Yang, Zhi|Bian, Xiuwu|Shao, Jimin|Li, Jianming|Lai, Maode|Shen, Junjie|Qian, Cheng
PMID: 26840943
Journal: Nat Commun. 2016 Feb 15;7:10711.
Title: The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition.
Author: Weyemi, Urbain|Redon, Christophe E|Choudhuri, Rohini|Aziz, Towqir|Maeda, Daisuke|Boufraqech, Myriem|Parekh, Palak R|Sethi, Taresh K|Kasoji, Manjula|Abrams, Natalie|Merchant, Anand|Rajapakse, Vinodh N|Bonner, William M
PMID: 26876487
Journal: Oncotarget. 2016 Mar 22;7(12):13854-64.
Title: Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.
Author: Suman, Suman|Das, Trinath P|Sirimulla, Suman|Alatassi, Houda|Ankem, Murali K|Damodaran, Chendil
PMID: 26883103
Journal: Neoplasma. 2016;63(3):351-61.
Title: Physcion 8-O-beta-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN.
Author: Ding, Z|Xu, F|Tang, J|Li, G|Jiang, P|Tang, Z|Wu, H
PMID: 26925795
Journal: Cancer Med. 2016 Jun;5(6):1268-78.
Title: Role of cancer stem cells in racial disparity in colorectal cancer.
Author: Farhana, Lulu|Antaki, Fadi|Anees, Mohammad R|Nangia-Makker, Pratima|Judd, Stephanie|Hadden, Timothy|Levi, Edi|Murshed, Farhan|Yu, Yingjie|Van Buren, Eric|Ahmed, Kulsoom|Dyson, Gregory|Majumdar, Adhip P N
PMID: 26990997
Journal: Onco Targets Ther. 2016 Feb 29;9:1011-21.
Title: Overexpression of Livin promotes migration and invasion of colorectal cancer cells by induction of epithelial-mesenchymal transition via NF-kappaB activation.
Author: Ge, Yang|Cao, Xiankui|Wang, Dalu|Sun, Wei|Sun, Hongli|Han, Bing|Cui, Junpeng|Liu, Baolin
PMID: 27013894
Journal: Clin Cancer Res. 2016 Sep 1;22(17):4491-504.
Title: Lysyl Oxidase (LOX) Transcriptionally Regulates SNAI2 Expression and TIMP4 Secretion in Human Cancers.
Author: Boufraqech, Myriem|Zhang, Lisa|Nilubol, Naris|Sadowski, Samira M|Kotian, Shweta|Quezado, Martha|Kebebew, Electron
PMID: 27029493
Journal: Mol Ther. 2016 Aug;24(7):1199-215.
Title: CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis.
Author: Zheng, Jian|Liu, Xiaobai|Wang, Ping|Xue, Yixue|Ma, Jun|Qu, Chengbin|Liu, Yunhui
PMID: 27058823
Journal: Oncotarget. 2016 May 24;7(21):31336-49.
Title: Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer.
Author: Kan, Jung-Yu|Yen, Meng-Chi|Wang, Jaw-Yuan|Wu, Deng-Chyang|Chiu, Yen-Jung|Ho, Ya-Wen|Kuo, Po-Lin
PMID: 27150059
Journal: Oncotarget. 2016 Jul 5;7(27):41306-41319.
Title: microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway.
Author: Chen, Yiyu|Jiang, Jingwen|Zhao, Mengyang|Luo, Xiaojun|Liang, Zixi|Zhen, Yan|Fu, Qiaofen|Deng, Xiaojie|Lin, Xian|Li, Libo|Luo, Rongcheng|Liu, Zhen|Fang, Weiyi
PMID: 27191497
Journal: Oncotarget. 2016 Jul 5;7(27):42183-42194.
Title: Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO.
Author: Yang, Peng|Chen, Tao|Xu, Zipeng|Zhu, Hua|Wang, Jie|He, Zhenyu
PMID: 27259250
Journal: Cell Cycle. 2016 Sep 16;15(18):2398-404.
Title: Twist1 and Slug mediate H2AX-regulated epithelial-mesenchymal transition in breast cells.
Author: Weyemi, Urbain|Redon, Christophe E|Sethi, Taresh K|Burrell, Allison S|Jailwala, Parthav|Kasoji, Manjula|Abrams, Natalie|Merchant, Anand|Bonner, William M
PMID: 27315462
Journal: Biochem Biophys Res Commun. 2016 Sep 2;477(4):801-806.
Title: Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation.
Author: Tashiro, Etsu|Henmi, Shizuka|Odake, Hiroyuki|Ino, Seitaro|Imoto, Masaya
PMID: 27369075
Journal: Adv Exp Med Biol. 2016;937:71-92.
Title: Interplay Between Transcription Factors and MicroRNAs Regulating Epithelial-Mesenchymal Transitions in Colorectal Cancer.
Author: Kaller, Markus|Hermeking, Heiko
PMID: 27573895
Journal: Oncogenesis. 2016 Sep 12;5(9):e258.
Title: The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition.
Author: Komiya, Y|Onodera, Y|Kuroiwa, M|Nomimura, S|Kubo, Y|Nam, J-M|Kajiwara, K|Nada, S|Oneyama, C|Sabe, H|Okada, M
PMID: 27617642
Journal: Oncogene. 2017 Mar 30;36(13):1779-1792.
Title: FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of beta-catenin transcriptional activity.
Author: Liu, C-C|Cai, D-L|Sun, F|Wu, Z-H|Yue, B|Zhao, S-L|Wu, X-S|Zhang, M|Zhu, X-W|Peng, Z-H|Yan, D-W
PMID: 27641329
Journal: Hum Pathol. 2017 Feb;60:151-159.
Title: Tumor budding at the invasive front of colorectal cancer may not be associated with the epithelial-mesenchymal transition.
Author: Yamada, Noriyuki|Sugai, Tamotsu|Eizuka, Makoto|Tsuchida, Koudai|Sugimoto, Ryo|Mue, Yoshiharu|Suzuki, Masamichi|Osakabe, Mitsumasa|Uesugi, Noriyuki|Ishida, Kazuyuki|Otsuka, Kouki|Matsumoto, Takayuki
PMID: 27836787
Journal: Biomed Pharmacother. 2017 Mar;87:366-374.
Title: Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma.
Author: Li, Xiang|Zhang, Guohui|Wang, Yan|Elgehama, Ahmed|Sun, Yang|Li, Lele|Gu, Yanhong|Guo, Wenjie|Xu, Qiang
PMID: 28068625
Journal: Onco Targets Ther. 2017 Feb 24;10:1191-1198.
Title: Long non-coding RNA CCAT2 is associated with poor prognosis in hepatocellular carcinoma and promotes tumor metastasis by regulating Snail2-mediated epithelial-mesenchymal transition.
Author: Xu, Yongfu|Wang, Binfeng|Zhang, Fabiao|Wang, Aidong|Du, Xuefeng|Hu, Peng|Zhu, Yu|Fang, Zheping
PMID: 28280353
Journal: Exp Oncol. 2017 Mar;39(1):17-24.
Title: Effect of antitumor drugs in low concentrationson the biological, immunophenotypic and cytogenetic characteristics of human colon cancer cells in vitro.
Author: Bezdenezhnykh, N|Kovalova, O|Lykhova, O|Kocherga, R|Vorontsova, A|Zhylchuk, V|Maksimyak, G I|Kudryavets, Yu
PMID: 28361849
Journal: Int J Mol Med. 2017 May;39(5):1277-1284.
Title: SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
Author: Xu, Chun-Yan|Liu, Shi-Quan|Qin, Meng-Bin|Zhuge, Chun-Feng|Qin, Lin|Qin, Nan|Lai, Ming-Yu|Huang, Jie-An
PMID: 28405684
Journal: Biochem Biophys Res Commun. 2017 Jun 3;487(3):580-586.
Title: Peroxiredoxin 5 promotes the epithelial-mesenchymal transition in colon cancer.
Author: Ahn, Hye-Mi|Yoo, Jin-Woo|Lee, Seunghoon|Lee, Hong Jun|Lee, Hyun-Shik|Lee, Dong-Seok
PMID: 28431931
Journal: Cell Death Dis. 2017 May 25;8(5):e2819.
Title: Human MSCs promotes colorectal cancer epithelial-mesenchymal transition and progression via CCL5/beta-catenin/Slug pathway.
Author: Chen, Ke|Liu, Qianqian|Tsang, Lai Ling|Ye, Qiao|Chan, Hsiao Chang|Sun, Yunwei|Jiang, Xiaohua
PMID: 28542126
Journal: Sci Rep. 2017 Jul 5;7(1):4687.
Title: Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression.
Author: Rokavec, Matjaz|Kaller, Markus|Horst, David|Hermeking, Heiko
PMID: 28680090
Journal: Sci Rep. 2017 Sep 8;7(1):10939.
Title: SATB2/beta-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer.
Author: Yu, Wei|Ma, Yiming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 28887549
Journal: Exp Cell Res. 2017 Dec 15;361(2):257-264.
Title: Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators.
Author: Afaloniati, Hara|Karagiannis, George S|Hardas, Alexandros|Poutahidis, Theofilos|Angelopoulou, Katerina
PMID: 29107070
Journal: BMC Cancer. 2017 Dec 4;17(1):813.
Title: Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-kappaB/slug/E-cadherin pathway.
Author: Zhou, Panpan|Wang, Chunling|Hu, Zebin|Chen, Wenruo|Qi, Wentao|Li, Aike
PMID: 29202800
Journal: Cell Death Dis. 2018 Jan 16;9(2):18.
Title: Ecotropic viral integration site 1 promotes metastasis independent of epithelial mesenchymal transition in colon cancer cells.
Author: Nayak, Kasturi Bala|Sajitha, I S|Kumar, T R Santhosh|Chakraborty, Soumen
PMID: 29339729
Journal: PLoS One. 2018 Feb 20;13(2):e0192958.
Title: Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence.
Author: Marcuello, Maria|Mayol, Xavier|Felipe-Fumero, Eloisa|Costa, Jaume|Lopez-Hierro, Laia|Salvans, Silvia|Alonso, Sandra|Pascual, Marta|Grande, Luis|Pera, Miguel
PMID: 29462209
Journal: J Mol Histol. 2018 Jun;49(3):235-244.
Title: Smad4 and epithelial-mesenchymal transition proteins in colorectal carcinoma: an immunohistochemical study.
Author: Ioannou, M|Kouvaras, E|Papamichali, R|Samara, M|Chiotoglou, I|Koukoulis, G
PMID: 29468299
Journal: BMC Genomics. 2018 Feb 9;19(Suppl 3):113.
Title: HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer.
Author: Pudova, Elena A|Kudryavtseva, Anna V|Fedorova, Maria S|Zaretsky, Andrew R|Shcherbo, Dmitry S|Lukyanova, Elena N|Popov, Anatoly Y|Sadritdinova, Asiya F|Abramov, Ivan S|Kharitonov, Sergey L|Krasnov, George S|Klimina, Kseniya M|Koroban, Nadezhda V|Volchenko,
PMID: 29504907
Journal: Int J Cancer. 2018 Aug 15;143(4):921-930.
Title: Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells.
Author: Zhou, Min|Liu, Xinjian|Li, Zonghai|Huang, Qian|Li, Fang|Li, Chuan-Yuan
PMID: 29524226
Journal: Cancer Lett. 2018 Jul 1;425:78-87.
Title: Long non-coding RNA SNHG15 interacts with and stabilizes transcription factor Slug and promotes colon cancer progression.
Author: Jiang, Hao|Li, Tingting|Qu, Yi|Wang, Xiang|Li, Bing|Song, Jiagui|Sun, Xiaoran|Tang, Yan|Wan, Junhu|Yu, Yu|Zhan, Jun|Zhang, Hongquan
PMID: 29604394
Journal: Cell Physiol Biochem. 2018;46(2):860-872.
Title: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
Author: Leng, Zhengwei|Xia, Qinghua|Chen, Jinhuang|Li, Yong|Xu, Jiqian|Zhao, Ende|Zheng, Hai|Ai, Walden|Dong, Jiangchuan
PMID: 29627827
Journal: Redox Biol. 2018 Jul;17:224-235.
Title: DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells.
Author: Kang, Kyoung Ah|Ryu, Yea Seong|Piao, Mei Jing|Shilnikova, Kristina|Kang, Hee Kyoung|Yi, Joo Mi|Boulanger, Mathias|Paolillo, Rosa|Bossis, Guillaume|Yoon, Sung Young|Kim, Seong Bong|Hyun, Jin Won
PMID: 29715584
Journal: Cell Physiol Biochem. 2018;46(5):1895-1906.
Title: MEGF6 Promotes the Epithelial-to-Mesenchymal Transition via the TGFbeta/SMAD Signaling Pathway in Colorectal Cancer Metastasis.
Author: Hu, Hanqing|Wang, Meng|Wang, Hongwei|Liu, Zheng|Guan, Xu|Yang, Runkun|Huang, Rui|Tang, Qingchao|Zou, Chaoxia|Wang, Guiyu|Gao, Xu|Wang, Xishan
PMID: 29719292
Journal: J Transl Med. 2018 Jun 19;16(1):169.
Title: CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E-cadherin.
Author: Xu, Jingjing|Zhou, Jun|Dai, Hanjue|Liu, Fei|Li, Wenjing|Wang, Wenjuan|Guo, Feng
PMID: 29921293
Journal: J Ginseng Res. 2018 Jul;42(3):288-297.
Title: Korean Red Ginseng extract reduces hypoxia-induced epithelial-mesenchymal transition by repressing NF-kappaB and ERK1/2 pathways in colon cancer.
Author: Kim, Eui Joo|Kwon, Kwang An|Lee, Young Eun|Kim, Ju Hyun|Kim, Se-Hee|Kim, Jung Ho
PMID: 29983610
Journal: Mar Drugs. 2018 Jul 29;16(8). pii: md16080252.
Title: Manzamine A Exerts Anticancer Activity against Human Colorectal Cancer Cells.
Author: Lin, Li-Chun|Kuo, Tzu-Ting|Chang, Hsin-Yi|Liu, Wen-Shan|Hsia, Shih-Min|Huang, Tsui-Chin
PMID: 30060617
Journal: J Cancer. 2018 Jun 23;9(15):2702-2712.
Title: Analysis of the expression of cancer-associated fibroblast- and EMT-related proteins in submucosal invasive colorectal cancer.
Author: Sugai, Tamotsu|Uesugi, Noriyuki|Kitada, Yuriko|Yamada, Noriyuki|Osakabe, Mitsumasa|Eizuka, Makoto|Sugimoto, Ryo|Fujita, Yasuko|Kawasaki, Keisuke|Yamamoto, Eiichiro|Yamano, Hiroo|Suzuki, Hiromu|Matsumoto, Takayuki
PMID: 30087711
Journal: Front Physiol. 2018 Jul 31;9:941.
Title: Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.
Author: Yabasin, Iddrisu B|Sanches, Jaceline G P|Ibrahim, Mohammed M|Huidan, Jin|Williams, Walana|Lu, Zhi-Li|Wen, Qingping
PMID: 30108509
Journal: J Exp Clin Cancer Res. 2018 Sep 19;37(1):231.
Title: HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways.
Author: Li, Qing|Wang, Cong|Wang, Yufeng|Sun, Liankang|Liu, Zhikui|Wang, Liang|Song, Tao|Yao, Yingmin|Liu, Qingguang|Tu, Kangsheng
PMID: 30231922
Journal: Evid Based Complement Alternat Med. 2018 Sep 25;2018:1495768.
Title: Jiedu Sangen Decoction Inhibits Migration and Invasion of Colon Cancer SW480 Cells via Suppressing Epithelial Mesenchymal Transition.
Author: Zhang, Kai|Peng, Tao|Yan, Qingying|Sun, Leitao|Miao, Haojun|Yuan, Li|Hong, Yuxin|Zhou, Mengmeng|Guo, Kaibo|Zhang, Leyin|Fang, Jing|Shen, Minhe|Ruan, Shanming
PMID: 30356400