Primary Site >> Stomach Cancer

Gene >> SMAD4

Journal:
Title: Juvenile Polyposis Syndrome
Author: Larsen Haidle, Joy|Howe, James R
PMID: 20301642
Journal: Oncogene. 1996 Dec 5;13(11):2459-62.
Title: Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms.
Author: Lei, J|Zou, T T|Shi, Y Q|Zhou, X|Smolinski, K N|Yin, J|Souza, R F|Appel, R|Wang, S|Cymes, K|Chan, O|Abraham, J M|Harpaz, N|Meltzer, S J
PMID: 8957088
Journal: Jpn J Cancer Res. 1997 Apr;88(4):335-9.
Title: Analysis of the DPC4 gene in gastric carcinoma.
Author: Nishizuka, S|Tamura, G|Maesawa, C|Sakata, K|Suzuki, Y|Iwaya, T|Terashima, M|Saito, K|Satodate, R
PMID: 9197522
Journal: Cancer Res. 1997 Oct 1;57(19):4221-4.
Title: Inactivation of Smad4 in gastric carcinomas.
Author: Powell, S M|Harper, J C|Hamilton, S R|Robinson, C R|Cummings, O W
PMID: 9331080
Journal: Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):49-58.
Title: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice.
Author: Weinstein, M|Yang, X|Deng, C
PMID: 10708952
Journal: Clin Cancer Res. 2001 Feb;7(2):277-82.
Title: Preserved Smad4 expression in the transforming growth factor beta signaling pathway is a favorable prognostic factor in patients with advanced gastric cancer.
Author: Xiangming, C|Natsugoe, S|Takao, S|Hokita, S|Ishigami, S|Tanabe, G|Baba, M|Kuroshima, K|Aikou, T
PMID: 11234879
Journal: Biochem Biophys Res Commun. 2001 Nov 30;289(2):350-7.
Title: Systematic analysis of the TGF-beta-Smad signaling pathway in gastrointestinal cancer cells.
Author: Ijichi, H|Ikenoue, T|Kato, N|Mitsuno, Y|Togo, G|Kato, J|Kanai, F|Shiratori, Y|Omata, M
PMID: 11716479
Journal: Lab Invest. 2002 Sep;82(9):1201-8.
Title: Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer.
Author: Chang, Yu-Ting|Wu, Ming-Shiang|Chang, Chee-Jen|Huang, Pei-Hsin|Hsu, Su-Ming|Lin, Jaw-Town
PMID: 12218081
Journal: Am J Pathol. 2002 Oct;161(4):1207-13.
Title: Different pattern of allelic loss in Epstein-Barr virus-positive gastric cancer with emphasis on the p53 tumor suppressor pathway.
Author: van Rees, Bastiaan P|Caspers, Eric|zur Hausen, Axel|van den Brule, Adriaan|Drillenburg, Paul|Weterman, Marian A J|Offerhaus, G Johan A
PMID: 12368194
Journal: Oncogene. 2003 Oct 30;22(49):7838-47.
Title: Interferon-gamma suppresses transforming growth factor-beta-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model.
Author: Kuga, Hirotaka|Morisaki, Takashi|Nakamura, Katsuya|Onishi, Hideya|Noshiro, Hirokazu|Uchiyama, Akihiko|Tanaka, Masao|Katano, Mitsuo
PMID: 14586410
Journal: APMIS. 2003 Dec;111(12):1105-13.
Title: Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis.
Author: Nam, Seon Young|Lee, Hye Seung|Jung, Gyung-Ah|Choi, Jimi|Cho, Sung Jin|Kim, Min Kyu|Kim, Woo Ho|Lee, Byung Lan
PMID: 14678019
Journal: Cancer Lett. 2003 Jul 10;196(2):197-206.
Title: Aberrant signaling of TGF-beta1 by the mutant Smad4 in gastric cancer cells.
Author: Ju, Hyang Ran|Jung, Uhee|Sonn, Chung Hee|Yoon, Suk Ran|Jeon, Jun Ho|Yang, Young|Lee, Kee Nyung|Choi, Inpyo
PMID: 12860278
Journal: J Pathol. 2003 May;200(1):39-46.
Title: Tumour suppressor gene expression correlates with gastric cancer prognosis.
Author: Lee, Hye Seung|Lee, Hyeon Kook|Kim, Hee Sung|Yang, Han-Kwang|Kim, Woo Ho
PMID: 12692839
Journal: Clin Cancer Res. 2004 Mar 1;10(5):1698-705.
Title: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma.
Author: Lee, Hye Seung|Chang, Mee Soo|Yang, Han-Kwang|Lee, Byung Lan|Kim, Woo Ho
PMID: 15014022
Journal: Ann Oncol. 2004 Apr;15(4):574-80.
Title: Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomas.
Author: Kim, Y H|Lee, H S|Lee, H-J|Hur, K|Kim, W H|Bang, Y-J|Kim, S-J|Lee, K U|Choe, K J|Yang, H-K
PMID: 15033661
Journal: J Med Genet. 2004 Jul;41(7):484-91.
Title: The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations.
Author: Howe, J R|Sayed, M G|Ahmed, A F|Ringold, J|Larsen-Haidle, J|Merg, A|Mitros, F A|Vaccaro, C A|Petersen, G M|Giardiello, F M|Tinley, S T|Aaltonen, L A|Lynch, H T
PMID: 15235019
Journal: Eur J Cancer. 2004 Aug;40(12):1897-903.
Title: E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients.
Author: Oliveira, Carla|Ferreira, Paulo|Nabais, Sergio|Campos, Luisa|Ferreira, Ana|Cirnes, Luis|Alves, Catarina Castro|Veiga, Isabel|Fragoso, Maria|Regateiro, Fernando|Dias, Luis Moreira|Moreira, Herculano|Suriano, Gianpaolo|Machado, Jose Carlos|Lopes, Carlos|Cas
PMID: 15288293
Journal: Clin Cancer Res. 2004 Oct 15;10(20):6938-45.
Title: Concomitant overexpression of cyclooxygenase-2 in HER-2-positive on Smad4-reduced human gastric carcinomas is associated with a poor patient outcome.
Author: Okano, Hirokazu|Shinohara, Hisashi|Miyamoto, Akiko|Takaori, Kyoichi|Tanigawa, Nobuhiko
PMID: 15501972
Journal: Histol Histopathol. 2005 Apr;20(2):543-9.
Title: Smad4 expression in gastric adenoma and adenocarcinoma: frequent loss of expression in diffuse type of gastric adenocarcinoma.
Author: Kim, J Y|Park, D Y|Kim, G H|Choi, K U|Lee, C H|Huh, G Y|Sol, M Y|Song, G A|Jeon, T Y|Kim, D H|Sim, M S
PMID: 15736060
Journal: J Med Invest. 2005 Aug;52(3-4):191-202.
Title: Histological and immunohistochemical study of composite neuroendocrine-exocrine carcinomas of the stomach.
Author: Rayhan, Nasim|Sano, Toshiaki|Qian, Zhi Rong|Obari, Abdul Kader|Hirokawa, Mitsuyoshi
PMID: 16167538
Journal: Oncogene. 2005 Dec 1;24(54):8012-24.
Title: Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer.
Author: Katuri, Varalakshmi|Tang, Yi|Marshall, Blair|Rashid, Asif|Jogunoori, Wilma|Volpe, Eugene A|Sidawy, Anton N|Evans, Stephen|Blay, Jonathan|Gallicano, G Ian|Premkumar Reddy, E|Mishra, Lopa|Mishra, Bibhuti
PMID: 16158060
Journal: Cancer Biol Ther. 2005 Jul;4(7):694-9. Epub 2005 Jul 13.
Title: The role of PRAJA and ELF in TGF-beta signaling and gastric cancer.
Author: Mishra, Lopa|Katuri, Varalakshmi|Evans, Stephen
PMID: 16096365
Journal: Am J Med Genet A. 2005 Apr 30;134(3):326-9.
Title: Gastric juvenile polyposis associated with germline SMAD4 mutation.
Author: Shikata, Kentaro|Kukita, Yoji|Matsumoto, Takayuki|Esaki, Motohiro|Yao, Takashi|Mochizuki, Yuichi|Hayashi, Kenshi|Iida, Mitsuo
PMID: 15754356
Journal: J Oral Pathol Med. 2005 Jan;34(1):23-9.
Title: Orofacial and gastrointestinal hyperplasia and neoplasia in smad4+/- and elf+/-/smad4+/- mutant mice.
Author: Redman, Robert S|Katuri, Varalakshmi|Tang, Yi|Dillner, Allan|Mishra, Bibhuti|Mishra, Lopa
PMID: 15610403
Journal: Cancer. 2005 Apr 1;103(7):1439-46.
Title: Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach.
Author: Kim, Min A|Lee, Hye Seung|Yang, Han-Kwang|Kim, Woo Ho
PMID: 15726543
Journal: Clin Cancer Res. 2005 Apr 1;11(7):2518-25.
Title: Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer.
Author: Lee, Byung Lan|Lee, Hye Seung|Jung, Jieun|Cho, Sung Jin|Chung, Hee-Yong|Kim, Woo Ho|Jin, Young-Woo|Kim, Chong Soon|Nam, Seon Young
PMID: 15814628
Journal: Biochem Biophys Res Commun. 2006 Jun 16;344(4):1216-23. Epub 2006 Apr 19.
Title: TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF.
Author: Kim, Sang Soo|Shetty, Kirti|Katuri, Varalakshmi|Kitisin, Krit|Baek, Hye Jung|Tang, Yi|Marshall, Blair|Johnson, Lynt|Mishra, Bibhuti|Mishra, Lopa
PMID: 16650383
Journal: World J Gastroenterol. 2006 May 21;12(19):3000-5.
Title: Selective inhibition of cell growth by activin in SNU-16 cells.
Author: Kim, Young-Il|Lee, Hee-Joo|Khang, Inkoo|Cho, Byung-Nam|Lee, Ha Kyu
PMID: 16718778
Journal: Hum Pathol. 2007 Jun;38(6):903-13. Epub 2007 Mar 21.
Title: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Author: Milne, Anya N A|Sitarz, Robert|Carvalho, Ralph|Polak, Mirjam M|Ligtenberg, Marjolijn|Pauwels, Patrick|Offerhaus, G Johan A|Weterman, Marian A J
PMID: 17376510
Journal: J Med Genet. 2007 Nov;44(11):702-9. Epub 2007 Sep 14.
Title: High proportion of large genomic deletions and a genotype phenotype update in 80 unrelated families with juvenile polyposis syndrome.
Author: Aretz, S|Stienen, D|Uhlhaas, S|Stolte, M|Entius, M M|Loff, S|Back, W|Kaufmann, A|Keller, K-M|Blaas, S H|Siebert, R|Vogt, S|Spranger, S|Holinski-Feder, E|Sunde, L|Propping, P|Friedl, W
PMID: 17873119
Journal: Mod Pathol. 2007 Aug;20(8):835-42. Epub 2007 May 11.
Title: Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer.
Author: Kim, Ji Hun|Kim, Min Kyu|Lee, Hee Eun|Cho, Sung Jin|Cho, Yu Jin|Lee, Byung Lan|Lee, Hye Seung|Nam, Seon Young|Lee, Jae-Seon|Kim, Woo Ho
PMID: 17491598
Journal: Clin Cancer Res. 2007 Jan 1;13(1):102-10.
Title: Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
Author: Wang, Li-Hui|Kim, Seok-Hyung|Lee, Jung Hyun|Choi, Yoon-La|Kim, Young Chul|Park, Tae Sung|Hong, Yun-Chul|Wu, Chun-Fu|Shin, Young Kee
PMID: 17200344
Journal: Dig Dis Sci. 2007 Jan;52(1):240-7. Epub 2006 Dec 14.
Title: Rebamipide inhibits gastric cancer cell growth.
Author: Tanigawa, Tetsuya|Pai, Rama|Arakawa, Tetsuo|Tarnawski, Andrzej S
PMID: 17171453
Journal: Am J Physiol Cell Physiol. 2007 Feb;292(2):C857-66. Epub 2006 Sep 20.
Title: Epigenetic regulation of integrin-linked kinase expression depending on adhesion of gastric carcinoma cells.
Author: Kim, Yong-Bae|Lee, Sung-Yul|Ye, Sang-Kyu|Lee, Jung Weon
PMID: 16987993
Journal: Arch Surg. 2008 Mar;143(3):311-2.
Title: Image of the month. Gastric juvenile polyposis (GJP) in germline SMAD4 mutation accompanied by gastric cancer.
Author: Gockel, Ines|Hansen, Torsten|Junginger, Theodor
PMID: 18347281
Journal: J Pathol. 2008 Aug;215(4):411-20.
Title: Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines.
Author: Barros, R|Pereira, B|Duluc, I|Azevedo, M|Mendes, N|Camilo, V|Jacobs, R J|Paulo, P|Santos-Silva, F|van Seuningen, I|van den Brink, G R|David, L|Freund, J-N|Almeida, R
PMID: 18498120
Journal: Anticancer Res. 2008 Mar-Apr;28(2A):1079-83.
Title: Immunohistochemical expression of P15 (INK4B) and SMAD4 in advanced gastric cancer.
Author: Sakellariou, Stratigoula|Liakakos, Theodore|Ghiconti, Ioanna|Hadjikokolis, Stamatis|Nakopoulou, Lydia|Pavlakis, Kitty
PMID: 18507057
Journal: J Pathol. 2008 Dec;216(4):471-82.
Title: Genome-wide analysis of DNA copy number alterations and gene expression in gastric cancer.
Author: Tsukamoto, Y|Uchida, T|Karnan, S|Noguchi, T|Nguyen, L T|Tanigawa, M|Takeuchi, I|Matsuura, K|Hijiya, N|Nakada, C|Kishida, T|Kawahara, K|Ito, H|Murakami, K|Fujioka, T|Seto, M|Moriyama, M
PMID: 18798223
Journal: Histol Histopathol. 2008 Dec;23(12):1439-52.
Title: Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence.
Author: Kim, Seok-Hyung|Lee, Seung-Hyun|Choi, Yoon-La|Wang, Li-Hui|Park, Cheol Keun|Shin, Young Kee
PMID: 18830930
Journal: Acta Biochim Biophys Sin (Shanghai). 2009 Aug;41(8):648-56.
Title: TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways.
Author: Fu, Hua|Hu, Zhongliang|Wen, Jifang|Wang, Kuansong|Liu, Ying
PMID: 19657566
Journal: Ai Zheng. 2009 May;28(5):538-42.
Title: [Correlations of TGF-betaRII, Smad4 and Smad7 expression to clinicopathologic characteristics and prognosis of gastric cancer].
Author: Lu, Bin|Zhou, Yong-Ning|Li, Qiang|Wu, Zheng-Qi|Zhang, Zhi-Yi|Ji, Rui|Guo, Qing-Hong|Liu, Wei
PMID: 19624886
Journal: J Cell Biochem. 2009 Jun 1;107(3):557-65.
Title: Jab1/CSN5 induces the cytoplasmic localization and degradation of RUNX3.
Author: Kim, Jang-Hyun|Choi, Joong-Kook|Cinghu, Senthilkumar|Jang, Ju-Won|Lee, You-Soub|Li, Ying-Hui|Goh, Yun-Mi|Chi, Xin-Zi|Lee, Kyeong-Sook|Wee, Heejun|Bae, Suk-Chul
PMID: 19350572
Journal: Exp Mol Pathol. 2009 Aug;87(1):48-53.
Title: Smad4/Smad7 balance: a role of tumorigenesis in gastric cancer.
Author: Leng, Aimin|Liu, Ting|He, Yongzheng|Li, Qian|Zhang, Guiying
PMID: 19341727
Journal: Cancer Sci. 2009 Oct;100(10):1809-16.
Title: c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma.
Author: Kiyono, Kunihiko|Suzuki, Hiroshi I|Morishita, Yasuyuki|Komuro, Akiyoshi|Iwata, Caname|Yashiro, Masakazu|Hirakawa, Kosei|Kano, Mitsunobu R|Miyazono, Kohei
PMID: 19594546
Journal: BMC Gastroenterol. 2010 Aug 12;10:91.
Title: Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer.
Author: Cho, Yu Jin|Kim, Ji Hun|Yoon, Jiyeon|Cho, Sung Jin|Ko, Young San|Park, Jong-Wan|Lee, Hye Seung|Lee, Hee Eun|Kim, Woo Ho|Lee, Byung Lan
PMID: 20704706
Journal: World J Gastroenterol. 2010 Nov 28;16(44):5635-41.
Title: Genetic variations in the SMAD4 gene and gastric cancer susceptibility.
Author: Wu, Dong-Mei|Zhu, Hai-Xia|Zhao, Qing-Hong|Zhang, Zhi-Zhong|Wang, Shi-Zhi|Wang, Mei-Lin|Gong, Wei-Da|Tan, Ming|Zhang, Zheng-Dong
PMID: 21105199
Journal: J Virol. 2011 Aug;85(15):7836-48.
Title: Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene.
Author: Iempridee, Tawin|Das, Shreyasi|Xu, Iris|Mertz, Janet E
PMID: 21593157
Journal: Helicobacter. 2011 Sep;16 Suppl 1:38-44.
Title: Gastric cancer: basic aspects.
Author: Resende, Carlos|Thiel, Alexandra|Machado, Jose C|Ristimaki, Ari
PMID: 21896084
Journal: Oncol Rep. 2012 Feb;27(2):559-66.
Title: Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis.
Author: Xiao, Bin|Zhu, En-Dong|Li, Na|Lu, Dong-Shui|Li, Wei|Li, Bo-Sheng|Zhao, Yong-Liang|Mao, Xu-Hu|Guo, Gang|Yu, Pei-Wu|Zou, Quan-Ming
PMID: 22020746
Journal: Int J Oncol. 2012 Sep;41(3):839-48.
Title: Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting betacatenin signaling.
Author: Kundu, Juthika|Wahab, S M Riajul|Kundu, Joydeb Kumar|Choi, Yoon-La|Erkin, Ozgur Cem|Lee, Hun Seok|Park, Sang Gyu|Shin, Young Kee
PMID: 22710759
Journal: Carcinogenesis. 2012 Oct;33(10):1985-92.
Title: Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells.
Author: Camilo, Vania|Barros, Rita|Sousa, Sofia|Magalhaes, Ana Maria|Lopes, Teresa|Mario Santos, Antonio|Pereira, Teresa|Figueiredo, Ceu|David, Leonor|Almeida, Raquel
PMID: 22791809
Journal: Nucleic Acids Res. 2012 Oct;40(18):9286-97.
Title: Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-beta signalling pathway.
Author: Zhang, Yan|Fan, Kai-Ji|Sun, Qiang|Chen, Ai-Zhong|Shen, Wen-Long|Zhao, Zhi-Hu|Zheng, Xiao-Fei|Yang, Xiao
PMID: 22821565
Journal: Cancer J. 2012 Jul-Aug;18(4):355-63.
Title: Genetic testing by cancer site: stomach.
Author: Chun, Nicki|Ford, James M
PMID: 22846738
Journal: Mol Imaging. 2012 Nov-Dec;11(6):507-15.
Title: Molecular imaging of gastric neoplasia with near-infrared fluorescent activatable probes.
Author: Ding, Shengli|Eric Blue, Randall|Chen, Yijing|Scull, Brooks|Kay Lund, Pauline|Morgan, Douglas
PMID: 23084251
Journal: J BUON. 2014 Jan-Mar;19(1):221-7.
Title: A study of Smad4 and Smad7 expression in surgically resected samples of gastric adenocarcinoma and their correlation with clinicopathological parameters and patient survival.
Author: Zizi-Sermpetzoglou, Adamantia|Myoteri, Despoina|Arkoumani, Elissavet|Voultsos, Mavroudis|Marinis, Athanasios
PMID: 24659668
Journal: PLoS One. 2014 Nov 5;9(11):e111693.
Title: High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.
Author: Kim, Seokhwi|Lee, Jeeyun|Hong, Min Eui|Do, In-Gu|Kang, So Young|Ha, Sang Yun|Kim, Seung Tae|Park, Se Hoon|Kang, Won Ki|Choi, Min-Gew|Lee, Jun Ho|Sohn, Tae Sung|Bae, Jae Moon|Kim, Sung|Kim, Duk-Hwan|Kim, Kyoung-Mee
PMID: 25372287
Journal: PLoS One. 2014 Oct 15;9(10):e110182.
Title: Meta-analysis of the prognostic value of smad4 immunohistochemistry in various cancers.
Author: Du, Yiping|Zhou, Xin|Huang, Zebo|Qiu, Tianzhu|Wang, Jian|Zhu, Wei|Wang, Tongshan|Liu, Ping
PMID: 25333693
Journal: Mol Med Rep. 2014 Oct;10(4):1999-2003.
Title: Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-beta signaling pathway.
Author: Chen, Fenglin|Zhuang, Mingkai|Peng, Jun|Wang, Xiaozhong|Huang, Tingxuan|Li, Sanmei|Lin, Manqiang|Lin, Hongming|Xu, Yating|Li, Jianying|Chen, Zhixin|Huang, Yuehong
PMID: 25109410
Journal: Mol Cancer Res. 2014 Aug;12(8):1088-99.
Title: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.
Author: Park, Jun Won|Jang, Seok Hoon|Park, Dong Min|Lim, Na Jung|Deng, Chuxia|Kim, Dae Yong|Green, Jeffrey E|Kim, Hark Kyun
PMID: 24784840
Journal: World J Surg Oncol. 2014 Jan 27;12:20.
Title: Functional outcomes by reconstruction technique following laparoscopic proximal gastrectomy for gastric cancer: double tract versus jejunal interposition.
Author: Nomura, Eiji|Lee, Sang-Woong|Kawai, Masaru|Yamazaki, Masashi|Nabeshima, Kazuhito|Nakamura, Kenji|Uchiyama, Kazuhisa
PMID: 24468278
Journal: Mol Carcinog. 2015 Nov;54(11):1521-7.
Title: Establishment and characterization of metastatic gastric cancer cell lines from murine gastric adenocarcinoma lacking Smad4, p53, and E-cadherin.
Author: Park, Jun Won|Park, Dong Min|Choi, Beom K|Kwon, Byoung S|Seong, Je Kyung|Green, Jeffrey E|Kim, Dae-Yong|Kim, Hark Kyun
PMID: 25307412
Journal: Cancer Biol Ther. 2015;16(5):764-9.
Title: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options.
Author: Miura, John T|Xiu, Joanne|Thomas, James|George, Ben|Carron, Benjamin R|Tsai, Susan|Johnston, Fabian M|Turaga, Kiran K|Gamblin, T Clark
PMID: 25778705
Journal: Cesk Patol. 2015;51(3):137-43.
Title: Pyloric gland adenoma: a histologic, immunohistochemical and molecular genetic study of 23 cases.
Author: Chlumska, Alena|Waloschek, Tomas|Mukensnabl, Petr|Martinek, Petr|Kaspirkova, Jana|Zamecnik, Michal
PMID: 26421956
Journal: Cancer Gene Ther. 2015 Dec;22(12):564-72.
Title: Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Smad4 and SGPP2.
Author: Ruoming, W|Zhen, Y|Tengteng, Z|Jisheng, H
PMID: 26494556
Journal: BMC Cancer. 2016 Feb 4;16:60.
Title: Differences in TGF-beta1 signaling and clinicopathologic characteristics of histologic subtypes of gastric cancer.
Author: Pak, Kyung Ho|Kim, Dong Hoon|Kim, Hyunki|Lee, Do Hyung|Cheong, Jae-Ho
PMID: 26846663
Journal: Biomed Res Int. 2016;2016:9604257.
Title: hsa-miR-376c-3p Regulates Gastric Tumor Growth Both In Vitro and In Vivo.
Author: Tu, Lin|Zhao, Enhao|Zhao, Wenyi|Zhang, Zizhen|Tang, Defeng|Zhang, Yeqian|Wang, Chaojie|Zhuang, Chun|Cao, Hui
PMID: 27965982
Journal: Cell Death Dis. 2016 Sep 29;7(9):e2382.
Title: miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression.
Author: Zheng, Liduan|Jiao, Wanju|Song, Huajie|Qu, Hongxia|Li, Dan|Mei, Hong|Chen, Yajun|Yang, Feng|Li, Huanhuan|Huang, Kai|Tong, Qiangsong
PMID: 27685626
Journal: Int J Colorectal Dis. 2016 Dec;31(12):1825-1833.
Title: Prophylactic total gastrectomy in the management of hereditary tumor syndromes.
Author: Pantelis, Dimitrios|Huneburg, Robert|Adam, Ronja|Holzapfel, Stefanie|Gevensleben, Heidrun|Nattermann, Jacob|Strassburg, Christian P|Aretz, Stefan|Kalff, Jorg C
PMID: 27682646
Journal: Oncotarget. 2016 Dec 13;7(50):82213-82227.
Title: Epstein-Barr virus BARF1-induced NFkappaB/miR-146a/SMAD4 alterations in stomach cancer cells.
Author: Kim, Dong Ha|Chang, Mee Soo|Yoon, Chan Jin|Middeldorp, Jaap M|Martinez, Olivia M|Byeon, Sun-Ju|Rha, Sun Young|Kim, Sung Han|Kim, Yang Soo|Woo, Jun Hee
PMID: 27438138
Journal: Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2057-65.
Title: Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development.
Author: Takeda, Haruna|Rust, Alistair G|Ward, Jerrold M|Yew, Christopher Chin Kuan|Jenkins, Nancy A|Copeland, Neal G
PMID: 27006499
Journal: Int J Oncol. 2016 May;48(5):1877-85.
Title: miR-148a downregulates the expression of transforming growth factor-beta2 and SMAD2 in gastric cancer.
Author: Zhang, Wei|Li, Yan
PMID: 26983401
Journal: Sci Rep. 2016 Mar 10;6:22982.
Title: Comprehensive molecular portrait using next generation sequencing of resected intestinal-type gastric cancer patients dichotomized according to prognosis.
Author: Bria, E|Pilotto, S|Simbolo, M|Fassan, M|de Manzoni, G|Carbognin, L|Sperduti, I|Brunelli, M|Cataldo, I|Tomezzoli, A|Mafficini, A|Turri, G|Karachaliou, N|Rosell, R|Tortora, G|Scarpa, A
PMID: 26961069
Journal: Stem Cells. 2016 May;34(5):1177-87.
Title: Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer.
Author: Park, Jun Won|Park, Jung Min|Park, Dong Min|Kim, Dae-Yong|Kim, Hark Kyun
PMID: 26869189
Journal: Cell Physiol Biochem. 2016;39(2):453-66.
Title: Smad2/3/4 Pathway Contributes to TGF-beta-Induced MiRNA-181b Expression to Promote Gastric Cancer Metastasis by Targeting Timp3.
Author: Zhou, Qi|Zheng, Xiao|Chen, Lujun|Xu, Bin|Yang, Xin|Jiang, Jingting|Wu, Changping
PMID: 27383203
Journal: Front Med (Lausanne). 2017 May 2;4:47.
Title: Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection.
Author: Rivas-Ortiz, Claudia I|Lopez-Vidal, Yolanda|Arredondo-Hernandez, Luis Jose Rene|Castillo-Rojas, Gonzalo
PMID: 28512631
Journal: JAMA Oncol. 2017 Nov 1;3(11):1546-1553.
Title: Genomic Profiling of Small-Bowel Adenocarcinoma.
Author: Schrock, Alexa B|Devoe, Craig E|McWilliams, Robert|Sun, James|Aparicio, Thomas|Stephens, Philip J|Ross, Jeffrey S|Wilson, Richard|Miller, Vincent A|Ali, Siraj M|Overman, Michael J
PMID: 28617917
Journal: Int J Oncol. 2017 Jun;50(6):1965-1976.
Title: miR196a5p modulates gastric cancer stem cell characteristics by targeting Smad4.
Author: Pan, Yunzhi|Shu, Xiong|Sun, Lichao|Yu, Long|Sun, Lixin|Yang, Zhihua|Ran, Yuliang
PMID: 28440445
Journal: Biochem Biophys Res Commun. 2017 Mar 11;484(3):631-635.
Title: Proteogenomic analysis of NCC-S1M, a gastric cancer stem cell-like cell line that responds to anti-PD-1.
Author: Park, Jun Won|Um, Hyejin|Yang, Hanna|Ko, Woori|Kim, Dae-Yong|Kim, Hark Kyun
PMID: 28153736
Journal: Gene. 2017 Mar 20;605:63-69.
Title: Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-beta1.
Author: Zhang, Renwen|Wang, Mingqi|Sui, Pengcheng|Ding, Lei|Yang, Qing
PMID: 28042090
Journal: Int J Oncol. 2017 Jan;50(1):272-282.
Title: Upregulation of SMAD4 by MZF1 inhibits migration of human gastric cancer cells.
Author: Lee, Jin-Hee|Kim, Sung-Su|Lee, Hun Seok|Hong, Sungyoul|Rajasekaran, Nirmal|Wang, Li-Hui|Choi, Joon-Seok|Shin, Young Kee
PMID: 27922669
Journal: Histopathology. 2018 Mar;72(4):556-568.
Title: Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.
Author: Kwon, Chae H|Kim, Young K|Lee, Sojeong|Kim, Ahrong|Park, Hye J|Choi, Yuri|Won, Yeo J|Park, Do Y|Lauwers, Gregory Y
PMID: 28873240
Journal: J Gastroenterol. 2018 Jun;53(6):725-739.
Title: miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway.
Author: Sun, Guang-Li|Li, Zheng|Wang, Wei-Zhi|Chen, Zheng|Zhang, Lei|Li, Qing|Wei, Song|Li, Bo-Wen|Xu, Jiang-Hao|Chen, Liang|He, Zhong-Yuan|Ying, Kai|Zhang, Xuan|Xu, Hao|Zhang, Dian-Cai|Xu, Ze-Kuan
PMID: 29103082
Journal: Mol Carcinog. 2018 Jul;57(7):947-954.
Title: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice.
Author: Park, Jun Won|Kim, Min-Sik|Voon, Dominic C|Kim, Su-Jin|Bae, Jingi|Mun, Dong-Gi|Ko, Seung-Ik|Kim, Hark K|Lee, Sang-Won|Kim, Dae-Yong
PMID: 29528141
Journal: Pathol Res Pract. 2018 Apr;214(4):475-481.
Title: Smad4/Fascin index is highly prognostic in patients with diffuse type EBV-associated gastric cancer.
Author: Son, Byoung Kwan|Kim, Dong-Hoon|Min, Kyueng-Whan|Kim, Eun-Kyung|Kwon, Mi Jung
PMID: 29572117
Journal: Cancer Res. 2018 Apr 15;78(8):1972-1985.
Title: ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis.
Author: Lu, Yun-Xin|Ju, Huai-Qiang|Liu, Ze-Xian|Chen, Dong-Liang|Wang, Yun|Zhao, Qi|Wu, Qi-Nian|Zeng, Zhao-Lei|Qiu, Hai-Bo|Hu, Pei-Shan|Wang, Zhi-Qiang|Zhang, Dong-Sheng|Wang, Feng|Xu, Rui-Hua
PMID: 29654155
Journal: Surg Case Rep. 2018 Jul 24;4(1):79.
Title: Non-familial juvenile polyposis of the stomach with gastric cancers: a case report.
Author: Jogo, Tomoko|Oki, Eiji|Fujiwara, Minako|Kurashige, Junji|Nakanishi, Ryota|Sugiyama, Masahiko|Nakashima, Yuichiro|Saeki, Hiroshi|Tsuruta, Shinichi|Nishimura, Masataka|Oda, Yoshinao|Maehara, Yoshihiko
PMID: 30043121
Journal: Surg Today. 2018 Aug 29. pii: 10.1007/s00595-018-1699-7.
Title: Functional evaluations comparing the double-tract method and the jejunal interposition method following laparoscopic proximal gastrectomy for gastric cancer: an investigation including laparoscopic total gastrectomy.
Author: Nomura, Eiji|Kayano, Hajime|Lee, Sang-Woong|Kawai, Masaru|Machida, Takashi|Yamamoto, Soichiro|Nabeshima, Kazuhito|Nakamura, Kenji|Mukai, Masaya|Uchiyama, Kazuhisa
PMID: 30159780