Primary Site >> Stomach Cancer
Gene >> SMAD3
| 1. | |||||||||||
| Journal: | Jpn J Clin Oncol. 1999 Jan;29(1):3-7. | ||||||||||
| Title: | No mutations of the Smad2 gene in human sporadic gastric carcinomas. | ||||||||||
| Author: | Shitara, Y|Yokozaki, H|Yasui, W|Takenoshita, S|Kuwano, H|Nagamachi, Y|Tahara, E | ||||||||||
| PMID: | 10073143 | ||||||||||
| 2. | |||||||||||
| Journal: | Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):49-58. | ||||||||||
| Title: | Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. | ||||||||||
| Author: | Weinstein, M|Yang, X|Deng, C | ||||||||||
| PMID: | 10708952 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2003 Oct 30;22(49):7838-47. | ||||||||||
| Title: | Interferon-gamma suppresses transforming growth factor-beta-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model. | ||||||||||
| Author: | Kuga, Hirotaka|Morisaki, Takashi|Nakamura, Katsuya|Onishi, Hideya|Noshiro, Hirokazu|Uchiyama, Akihiko|Tanaka, Masao|Katano, Mitsuo | ||||||||||
| PMID: | 14586410 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Biol Cell. 2004 Feb;15(2):420-34. | ||||||||||
| Title: | Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells. | ||||||||||
| Author: | Kim, Sang Gyun|Jong, Hyun-Soon|Kim, Tae-You|Lee, Jung Weon|Kim, Noe Kyeong|Hong, Seung Hwan|Bang, Yung-Jue | ||||||||||
| PMID: | 14595120 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncogene. 2004 Feb 19;23(7):1333-41. | ||||||||||
| Title: | Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. | ||||||||||
| Author: | Han, Sang-Uk|Kim, Heung-Tae|Seong, Do Hwan|Kim, Yong-Suk|Park, Yoon-Soo|Bang, Yung-Jue|Yang, Han-Kwang|Kim, Seong-Jin | ||||||||||
| PMID: | 14647420 | ||||||||||
| 6. | |||||||||||
| Journal: | Mol Cell Biol. 2005 Aug;25(16):6921-36. | ||||||||||
| Title: | The signaling network of transforming growth factor beta1, protein kinase Cdelta, and integrin underlies the spreading and invasiveness of gastric carcinoma cells. | ||||||||||
| Author: | Lee, Mi-Sook|Kim, Tae Young|Kim, Yong-Bae|Lee, Sung-Yul|Ko, Seong-Gyu|Jong, Hyun-Soon|Kim, Tae-You|Bang, Yung-Jue|Lee, Jung Weon | ||||||||||
| PMID: | 16055706 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Biol Ther. 2005 Jul;4(7):694-9. Epub 2005 Jul 13. | ||||||||||
| Title: | The role of PRAJA and ELF in TGF-beta signaling and gastric cancer. | ||||||||||
| Author: | Mishra, Lopa|Katuri, Varalakshmi|Evans, Stephen | ||||||||||
| PMID: | 16096365 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncogene. 2005 Dec 1;24(54):8012-24. | ||||||||||
| Title: | Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer. | ||||||||||
| Author: | Katuri, Varalakshmi|Tang, Yi|Marshall, Blair|Rashid, Asif|Jogunoori, Wilma|Volpe, Eugene A|Sidawy, Anton N|Evans, Stephen|Blay, Jonathan|Gallicano, G Ian|Premkumar Reddy, E|Mishra, Lopa|Mishra, Bibhuti | ||||||||||
| PMID: | 16158060 | ||||||||||
| 9. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2006 Jun 16;344(4):1216-23. Epub 2006 Apr 19. | ||||||||||
| Title: | TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF. | ||||||||||
| Author: | Kim, Sang Soo|Shetty, Kirti|Katuri, Varalakshmi|Kitisin, Krit|Baek, Hye Jung|Tang, Yi|Marshall, Blair|Johnson, Lynt|Mishra, Bibhuti|Mishra, Lopa | ||||||||||
| PMID: | 16650383 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncogene. 2008 Jan 24;27(5):675-83. Epub 2007 Jul 23. | ||||||||||
| Title: | CEACAM5 and CEACAM6 are major target genes for Smad3-mediated TGF-beta signaling. | ||||||||||
| Author: | Han, S-U|Kwak, T-H|Her, K H|Cho, Y-H|Choi, C|Lee, H-J|Hong, S|Park, Y S|Kim, Y-S|Kim, T-A|Kim, S-J | ||||||||||
| PMID: | 17653079 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Sci. 2009 Oct;100(10):1809-16. | ||||||||||
| Title: | c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma. | ||||||||||
| Author: | Kiyono, Kunihiko|Suzuki, Hiroshi I|Morishita, Yasuyuki|Komuro, Akiyoshi|Iwata, Caname|Yashiro, Masakazu|Hirakawa, Kosei|Kano, Mitsunobu R|Miyazono, Kohei | ||||||||||
| PMID: | 19594546 | ||||||||||
| 12. | |||||||||||
| Journal: | J Biol Chem. 2009 Jan 30;284(5):3334-44. | ||||||||||
| Title: | SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. | ||||||||||
| Author: | Takahata, Mami|Inoue, Yasumichi|Tsuda, Hitoshi|Imoto, Issei|Koinuma, Daizo|Hayashi, Makoto|Ichikura, Takashi|Yamori, Takao|Nagasaki, Koichi|Yoshida, Mika|Matsuoka, Masao|Morishita, Kazuhiro|Yuki, Keiko|Hanyu, Aki|Miyazawa, Keiji|Inazawa, Johji|Miyazono, K | ||||||||||
| PMID: | 19049980 | ||||||||||
| 13. | |||||||||||
| Journal: | J Virol. 2011 Aug;85(15):7836-48. | ||||||||||
| Title: | Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene. | ||||||||||
| Author: | Iempridee, Tawin|Das, Shreyasi|Xu, Iris|Mertz, Janet E | ||||||||||
| PMID: | 21593157 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncogene. 2012 Jan 12;31(2):226-37. | ||||||||||
| Title: | Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma. | ||||||||||
| Author: | Lo, S-S|Hung, P-S|Chen, J-H|Tu, H-F|Fang, W-L|Chen, C-Y|Chen, W-T|Gong, N-R|Wu, C-W | ||||||||||
| PMID: | 21666718 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncogene. 2012 Jun 21;31(25):3051-9. | ||||||||||
| Title: | Smad3 regulates E-cadherin via miRNA-200 pathway. | ||||||||||
| Author: | Ahn, S-M|Cha, J-Y|Kim, J|Kim, D|Trang, H T H|Kim, Y-M|Cho, Y-H|Park, D|Hong, S | ||||||||||
| PMID: | 22020340 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Mol Med. 2012 Mar;29(3):373-9. | ||||||||||
| Title: | TGF-beta1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis. | ||||||||||
| Author: | Lv, Zhi-Dong|Wang, Hai-Bo|Li, Fu-Nian|Wu, Li|Liu, Chen|Nie, Gang|Kong, Bin|Qu, Hui-Li|Li, Jian-Guo | ||||||||||
| PMID: | 22139024 | ||||||||||
| 17. | |||||||||||
| Journal: | Lab Invest. 2012 Jun;92(6):883-95. | ||||||||||
| Title: | Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature. | ||||||||||
| Author: | Nam, Ki Taek|O'Neal, Ryan|Lee, Yeo Song|Lee, Yong Chan|Coffey, Robert J|Goldenring, James R | ||||||||||
| PMID: | 22411066 | ||||||||||
| 18. | |||||||||||
| Journal: | J Pathol. 2012 Nov;228(3):391-404. | ||||||||||
| Title: | Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-beta. | ||||||||||
| Author: | Katsuno, Yoko|Ehata, Shogo|Yashiro, Masakazu|Yanagihara, Kazuyoshi|Hirakawa, Kosei|Miyazono, Kohei | ||||||||||
| PMID: | 22430847 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2012;7(4):e35684. | ||||||||||
| Title: | Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer. | ||||||||||
| Author: | Wu, Yijun|Li, Qi|Zhou, Xinhui|Yu, Jiren|Mu, Yunchuan|Munker, Stefan|Xu, Chengfu|Shen, Zhe|Mullenbach, Roman|Liu, Yan|Li, Li|Gretz, Norbert|Zieker, Derek|Li, Jun|Matsuzaki, Kouichi|Li, Youming|Dooley, Steven|Weng, Honglei | ||||||||||
| PMID: | 22539990 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2013 Nov 15;8(11):e81702. | ||||||||||
| Title: | Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways. | ||||||||||
| Author: | Dun, Boying|Sharma, Ashok|Teng, Yong|Liu, Haitao|Purohit, Sharad|Xu, Heng|Zeng, Lingwen|She, Jin-Xiong | ||||||||||
| PMID: | 24260584 | ||||||||||
| 21. | |||||||||||
| Journal: | World J Gastroenterol. 2013 May 14;19(18):2781-92. | ||||||||||
| Title: | MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. | ||||||||||
| Author: | Li, Dong-Mei|Zhang, Jun|Li, Wen-Mei|Cui, Jian-Tao|Pan, Yuan-Ming|Liu, Si-Qi|Xing, Rui|Lu, You-Yong | ||||||||||
| PMID: | 23687415 | ||||||||||
| 22. | |||||||||||
| Journal: | Dig Dis Sci. 2013 Apr;58(4):989-97. | ||||||||||
| Title: | Smad3 and Smad3 phosphoisoforms are prognostic markers of gastric carcinoma. | ||||||||||
| Author: | Kim, Seok-Hyung|Kim, Kyung-Hee|Ahn, Soomin|Hyeon, Jiyeon|Park, Cheol-Keun | ||||||||||
| PMID: | 23179147 | ||||||||||
| 23. | |||||||||||
| Journal: | Biochim Biophys Acta. 2013 Jun;1830(6):3584-92. | ||||||||||
| Title: | Transcriptional and post-translational regulation of Bim is essential for TGF-beta and TNF-alpha-induced apoptosis of gastric cancer cell. | ||||||||||
| Author: | Ha Thi, Huyen Trang|Lim, Hee-Sun|Kim, Jooyoung|Kim, Young-Mi|Kim, Hye-Youn|Hong, Suntaek | ||||||||||
| PMID: | 23500081 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncogene. 2014 Jun 26;33(26):3473-84. | ||||||||||
| Title: | Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis. | ||||||||||
| Author: | Wang, C|Li, Y|Zhang, H|Liu, F|Cheng, Z|Wang, D|Wang, G|Xu, H|Zhao, Y|Cao, L|Li, F | ||||||||||
| PMID: | 23934187 | ||||||||||
| 25. | |||||||||||
| Journal: | Dig Dis Sci. 2014 Mar;59(3):569-82. | ||||||||||
| Title: | Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell. | ||||||||||
| Author: | Donnelly, Jessica M|Engevik, Amy C|Engevik, Melinda|Schumacher, Michael A|Xiao, Chang|Yang, Li|Worrell, Roger T|Zavros, Yana | ||||||||||
| PMID: | 24202649 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2015 Jul 10;6(19):17661-74. | ||||||||||
| Title: | Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-beta1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit. | ||||||||||
| Author: | Liang, Xiuming|Zeng, Jiping|Wang, Lixiang|Shen, Li|Ma, Xueping|Li, Shuyan|Wu, Yujiao|Ma, Lin|Ci, Xinyu|Guo, Qing|Jia, Mutian|Shen, Haiyu|Sun, Yundong|Liu, Zhifang|Liu, Shili|Li, Wenjuan|Yu, Han|Chen, Chunyan|Jia, Jihui | ||||||||||
| PMID: | 25974964 | ||||||||||
| 27. | |||||||||||
| Journal: | Am J Cancer Res. 2015 May 15;5(6):1890-6. eCollection 2015. | ||||||||||
| Title: | TGF-beta induces fascin expression in gastric cancer via phosphorylation of smad3 linker area. | ||||||||||
| Author: | Li, Liling|Cao, Fang|Liu, Baoan|Luo, Xiaojuan|Ma, Xin|Hu, Zhongliang | ||||||||||
| PMID: | 26269751 | ||||||||||
| 28. | |||||||||||
| Journal: | Sci Rep. 2016 Dec 5;6:38376. | ||||||||||
| Title: | Establishment of a gastric cancer subline with high metastatic potential using a novel microfluidic system. | ||||||||||
| Author: | Chen, Zhe-Zhou|Li, Wan-Ming|Zhang, Yu|Yu, Min|Shan, Lian-Feng|Yuan, De-Zheng|Liu, Fu-Rong|Fang, Jin | ||||||||||
| PMID: | 27917905 | ||||||||||
| 29. | |||||||||||
| Journal: | Cell Physiol Biochem. 2016;40(6):1401-1409. | ||||||||||
| Title: | Bleomycin Suppresses the Proliferation and the Mobility of Human Gastric Cancer Cells Through the Smad Signaling Pathway. | ||||||||||
| Author: | Liu, Jin-Fang|Nie, Xiao-Cui|Shao, You-Cheng|Su, Wen-Hui|Ma, Hai-Ying|Xu, Xiao-Yan | ||||||||||
| PMID: | 27997887 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Oncol. 2016 Dec;49(6):2520-2528. | ||||||||||
| Title: | ADAM17 promotes epithelial-mesenchymal transition via TGF-beta/Smad pathway in gastric carcinoma cells. | ||||||||||
| Author: | Xu, Min|Zhou, Hailang|Zhang, Chunli|He, Junbo|Wei, Hong|Zhou, Meng|Lu, Ying|Sun, Yaocheng|Ding, Jerry Wanming|Zeng, Jian|Peng, Wanxin|Du, Fengyi|Gong, Aihua | ||||||||||
| PMID: | 27779657 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 15;7(46):75185-75196. | ||||||||||
| Title: | miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-beta signaling pathway. | ||||||||||
| Author: | Wei, Song|Li, Qing|Li, Zheng|Wang, Linjun|Zhang, Lei|Xu, Zekuan | ||||||||||
| PMID: | 27655675 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Lett. 2016 Oct 10;381(1):138-48. | ||||||||||
| Title: | RUNX3-mediated up-regulation of miR-29b suppresses the proliferation and migration of gastric cancer cells by targeting KDM2A. | ||||||||||
| Author: | Kong, Ye|Zou, Shuiyan|Yang, Fenghua|Xu, Xia|Bu, Wenhong|Jia, Jihui|Liu, Zhifang | ||||||||||
| PMID: | 27497248 | ||||||||||
| 33. | |||||||||||
| Journal: | Int J Oncol. 2016 May;48(5):1877-85. | ||||||||||
| Title: | miR-148a downregulates the expression of transforming growth factor-beta2 and SMAD2 in gastric cancer. | ||||||||||
| Author: | Zhang, Wei|Li, Yan | ||||||||||
| PMID: | 26983401 | ||||||||||
| 34. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2016 Apr;39(2):129-37. | ||||||||||
| Title: | PDCD2 and NCoR1 as putative tumor suppressors in gastric gastrointestinal stromal tumors. | ||||||||||
| Author: | Wang, Wei|Song, Xiao-Wen|Bu, Xian-Min|Zhang, Ning|Zhao, Cheng-Hai | ||||||||||
| PMID: | 26589942 | ||||||||||
| 35. | |||||||||||
| Journal: | Gene. 2017 Mar 20;605:63-69. | ||||||||||
| Title: | Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-beta1. | ||||||||||
| Author: | Zhang, Renwen|Wang, Mingqi|Sui, Pengcheng|Ding, Lei|Yang, Qing | ||||||||||
| PMID: | 28042090 | ||||||||||
| 36. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2017 Jan;21(2):258-265. | ||||||||||
| Title: | HOXA13 upregulation in gastric cancer is associated with enhanced cancer cell invasion and epithelial-to-mesenchymal transition. | ||||||||||
| Author: | He, Y-X|Song, X-H|Zhao, Z-Y|Zhao, H | ||||||||||
| PMID: | 28165563 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncotarget. 2017 May 16;8(20):34018. | ||||||||||
| Title: | Correction: miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-beta signaling pathway. | ||||||||||
| Author: | Wei, Song|Li, Qing|Li, Zheng|Wang, Linjun|Zhang, Lei|Xu, Zekuan | ||||||||||
| PMID: | 28521389 | ||||||||||
| 38. | |||||||||||
| Journal: | Evid Based Complement Alternat Med. 2017;2017:1871298. | ||||||||||
| Title: | Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-beta/Smad Pathway. | ||||||||||
| Author: | Wu, Ting-Ting|Lu, Jun|Zheng, Pei-Qiu|Liu, Shen-Lin|Wu, Jian|Sun, Wei|Sun, Qing-Min|Ma, Nai-Xia|Ding, Xue-Lian|Chen, Min|Zou, Xi | ||||||||||
| PMID: | 28539961 | ||||||||||
| 39. | |||||||||||
| Journal: | Mol Med Rep. 2018 Feb;17(2):2853-2860. | ||||||||||
| Title: | Effect and mechanism of RNAi targeting WWTR1 on biological activity of gastric cancer cells SGC7901. | ||||||||||
| Author: | Li, Yuan|Yang, Fang-Liang|Zhu, Chun-Fu|Tang, Li-Ming | ||||||||||
| PMID: | 29207147 | ||||||||||
| 40. | |||||||||||
| Journal: | DNA Cell Biol. 2018 Mar;37(3):244-252. | ||||||||||
| Title: | Melatonin Inhibits the Proliferation of Gastric Cancer Cells Through Regulating the miR-16-5p-Smad3 Pathway. | ||||||||||
| Author: | Zhu, Chenyu|Huang, Qun|Zhu, Hongyu | ||||||||||
| PMID: | 29359963 | ||||||||||
| 41. | |||||||||||
| Journal: | Cell Death Dis. 2018 May 29;9(6):649. | ||||||||||
| Title: | DSGOST regulates resistance via activation of autophagy in gastric cancer. | ||||||||||
| Author: | Kim, Tae Woo|Lee, Seon Young|Kim, Mia|Cheon, Chunhoo|Jang, Bo-Hyoung|Shin, Yong Cheol|Ko, Seong-Gyu | ||||||||||
| PMID: | 29844404 | ||||||||||
| 42. | |||||||||||
| Journal: | Biomed Pharmacother. 2018 Nov;107:168-176. | ||||||||||
| Title: | MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-beta/Smad3 signaling pathway. | ||||||||||
| Author: | Sun, Lu|Guo, Zhixian|Sun, Jihong|Li, Jingjing|Dong, Zihui|Zhang, Yize|Chen, Jianan|Kan, Quancheng|Yu, Zujiang | ||||||||||
| PMID: | 30086463 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Biol Ther. 2018 Aug 17:1-6. | ||||||||||
| Title: | Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient. | ||||||||||
| Author: | Zhou, Shujuan|Xu, Bo|Qi, Liang|Zhu, Dongqin|Liu, Baorui|Wei, Jia | ||||||||||
| PMID: | 30118648 | ||||||||||