Primary Site >> Stomach Cancer
Gene >> SMAD3
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Ref: No mutations of the Smad2 gene in human sporadic gastric carcinomas. PMID: 10073143 |
Ref: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. PMID: 10708952 |
Ref: Interferon-gamma suppresses transforming growth factor-beta-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model. PMID: 14586410 |
Ref: Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells. PMID: 14595120 Ref: Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. PMID: 14647420 |
Ref: The signaling network of transforming growth factor beta1, protein kinase Cdelta, and integrin underlies the spreading and invasiveness of gastric carcinoma cells. PMID: 16055706 Ref: The role of PRAJA and ELF in TGF-beta signaling and gastric cancer. PMID: 16096365 Ref: Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer. PMID: 16158060 |
Ref: TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF. PMID: 16650383 |
Ref: CEACAM5 and CEACAM6 are major target genes for Smad3-mediated TGF-beta signaling. PMID: 17653079 |
Ref: SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. PMID: 19049980 Ref: c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma. PMID: 19594546 |
Ref: Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene. PMID: 21593157 |
Ref: Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma. PMID: 21666718 Ref: Smad3 regulates E-cadherin via miRNA-200 pathway. PMID: 22020340 Ref: TGF-beta1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis. PMID: 22139024 Ref: Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature. PMID: 22411066 Ref: Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-beta. PMID: 22430847 Ref: Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer. PMID: 22539990 |
Ref: Smad3 and Smad3 phosphoisoforms are prognostic markers of gastric carcinoma. PMID: 23179147 Ref: Transcriptional and post-translational regulation of Bim is essential for TGF-beta and TNF-alpha-induced apoptosis of gastric cancer cell. PMID: 23500081 Ref: MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. PMID: 23687415 Ref: Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways. PMID: 24260584 |
Ref: Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis. PMID: 23934187 Ref: Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell. PMID: 24202649 |
Ref: Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-beta1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit. PMID: 25974964 Ref: TGF-beta induces fascin expression in gastric cancer via phosphorylation of smad3 linker area. PMID: 26269751 |
Ref: PDCD2 and NCoR1 as putative tumor suppressors in gastric gastrointestinal stromal tumors. PMID: 26589942 Ref: miR-148a downregulates the expression of transforming growth factor-beta2 and SMAD2 in gastric cancer. PMID: 26983401 Ref: RUNX3-mediated up-regulation of miR-29b suppresses the proliferation and migration of gastric cancer cells by targeting KDM2A. PMID: 27497248 Ref: miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-beta signaling pathway. PMID: 27655675 Ref: ADAM17 promotes epithelial-mesenchymal transition via TGF-beta/Smad pathway in gastric carcinoma cells. PMID: 27779657 Ref: Establishment of a gastric cancer subline with high metastatic potential using a novel microfluidic system. PMID: 27917905 Ref: Bleomycin Suppresses the Proliferation and the Mobility of Human Gastric Cancer Cells Through the Smad Signaling Pathway. PMID: 27997887 |
Ref: Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-beta1. PMID: 28042090 Ref: HOXA13 upregulation in gastric cancer is associated with enhanced cancer cell invasion and epithelial-to-mesenchymal transition. PMID: 28165563 Ref: Correction: miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-beta signaling pathway. PMID: 28521389 Ref: Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-beta/Smad Pathway. PMID: 28539961 |
Ref: Effect and mechanism of RNAi targeting WWTR1 on biological activity of gastric cancer cells SGC7901. PMID: 29207147 Ref: Melatonin Inhibits the Proliferation of Gastric Cancer Cells Through Regulating the miR-16-5p-Smad3 Pathway. PMID: 29359963 Ref: DSGOST regulates resistance via activation of autophagy in gastric cancer. PMID: 29844404 Ref: MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-beta/Smad3 signaling pathway. PMID: 30086463 Ref: Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient. PMID: 30118648 |