Literatures

Primary Site >> Colorectal Cancer

Gene >> SMAD2

1.
Journal:	Cell. 1996 Aug 23;86(4):543-52.
Title:	MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.
Author:	Eppert, K\|Scherer, S W\|Ozcelik, H\|Pirone, R\|Hoodless, P\|Kim, H\|Tsui, L C\|Bapat, B\|Gallinger, S\|Andrulis, I L\|Thomsen, G H\|Wrana, J L\|Attisano, L
PMID:	8752209

2.
Journal:	Leukemia. 1997 Aug;11(8):1187-92.
Title:	Smad5, a tumor suppressor candidate at 5q31.1, is hemizygously lost and not mutated in the retained allele in human leukemia cell line HL60.
Author:	Zavadil, J\|Brezinova, J\|Svoboda, P\|Zemanova, Z\|Michalova, K
PMID:	9264367

3.
Journal:	Cancer Res. 1997 Sep 1;57(17):3772-8.
Title:	Expression and mutational analysis of the DCC, DPC4, and MADR2/JV18-1 genes in neuroblastoma.
Author:	Kong, X T\|Choi, S H\|Inoue, A\|Xu, F\|Chen, T\|Takita, J\|Yokota, J\|Bessho, F\|Yanagisawa, M\|Hanada, R\|Yamamoto, K\|Hayashi, Y
PMID:	9288786

4.
Journal:	Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300.
Title:	Molecular biology of colorectal cancer.
Author:	Gryfe, R\|Swallow, C\|Bapat, B\|Redston, M\|Gallinger, S\|Couture, J
PMID:	9438104

5.
Journal:	Cancer Lett. 1998 Jan 9;122(1-2):157-63.
Title:	Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers.
Author:	Arai, T\|Akiyama, Y\|Okabe, S\|Ando, M\|Endo, M\|Yuasa, Y
PMID:	9464505

6.
Journal:	Carcinogenesis. 1998 May;19(5):803-7.
Title:	Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers.
Author:	Takenoshita, S\|Tani, M\|Mogi, A\|Nagashima, M\|Nagamachi, Y\|Bennett, W P\|Hagiwara, K\|Harris, C C\|Yokota, J
PMID:	9635866

7.
Journal:	Leukemia. 1998 Jul;12(7):1114-8.
Title:	Mutational analysis of the tumor suppressor Smad2 in acute lymphoid and myeloid leukemia.
Author:	Wieser, R\|Gruber, B\|Rieder, H\|Fonatsch, C
PMID:	9665198

8.
Journal:	Cell. 1998 Sep 18;94(6):703-14.
Title:	Smad3 mutant mice develop metastatic colorectal cancer.
Author:	Zhu, Y\|Richardson, J A\|Parada, L F\|Graff, J M
PMID:	9753318

9.
Journal:	Br J Cancer. 1998 Dec;78(12):1615-9.
Title:	Smad4 (DPC4)--a potent tumour suppressor?
Author:	Duff, E K\|Clarke, A R
PMID:	9862572

10.
Journal:	Oncogene. 1999 May 20;18(20):3098-103.
Title:	Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis.
Author:	Miyaki, M\|Iijima, T\|Konishi, M\|Sakai, K\|Ishii, A\|Yasuno, M\|Hishima, T\|Koike, M\|Shitara, N\|Iwama, T\|Utsunomiya, J\|Kuroki, T\|Mori, T
PMID:	10340381

11.
Journal:	Int J Cancer. 1999 Jul 19;82(2):197-202.
Title:	Expression of Smad proteins in human colorectal cancer.
Author:	Korchynskyi, O\|Landstrom, M\|Stoika, R\|Funa, K\|Heldin, C H\|ten Dijke, P\|Souchelnytskyi, S
PMID:	10389752

12.
Journal:	J Biol Chem. 1999 Aug 13;274(33):22919-22.
Title:	Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion.
Author:	Prunier, C\|Mazars, A\|Noe, V\|Bruyneel, E\|Mareel, M\|Gespach, C\|Atfi, A
PMID:	10438456

13.
Journal:	Gut. 1999 Sep;45(3):406-8.
Title:	Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome.
Author:	Bevan, S\|Woodford-Richens, K\|Rozen, P\|Eng, C\|Young, J\|Dunlop, M\|Neale, K\|Phillips, R\|Markie, D\|Rodriguez-Bigas, M\|Leggett, B\|Sheridan, E\|Hodgson, S\|Iwama, T\|Eccles, D\|Bodmer, W\|Houlston, R\|Tomlinson, I
PMID:	10446110

14.
Journal:	Jpn J Cancer Res. 1999 Aug;90(8):837-40.
Title:	Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.
Author:	Imai, Y\|Shiratori, Y\|Kato, N\|Inoue, T\|Omata, M
PMID:	10543255

15.
Journal:	J Biol Chem. 1999 Nov 19;274(47):33637-43.
Title:	Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells.
Author:	Calonge, M J\|Massague, J
PMID:	10559252

16.
Journal:	Jpn J Cancer Res. 1999 Dec;90(12):1329-37.
Title:	Frequent allelic imbalance on chromosome 18q21 in early superficial colorectal cancers.
Author:	Akiyama, Y\|Arai, T\|Nagasaki, H\|Yagi, O K\|Nakahata, A\|Nakajima, T\|Ohkura, Y\|Iwai, T\|Saitoh, K\|Yuasa, Y
PMID:	10665650

17.
Journal:	Eur J Cancer Prev. 1999 Dec;8 Suppl 1:S39-47.
Title:	Sequence of molecular genetic events in colorectal tumorigenesis.
Author:	Laurent-Puig, P\|Blons, H\|Cugnenc, P H
PMID:	10772417

18.
Journal:	Oncogene. 2000 Jan 27;19(4):546-55.
Title:	DCC and SMAD4 alterations in human colorectal and pancreatic tumor dissemination.
Author:	Tarafa, G\|Villanueva, A\|Farre, L\|Rodriguez, J\|Musulen, E\|Reyes, G\|Seminago, R\|Olmedo, E\|Paules, A B\|Peinado, M A\|Bachs, O\|Capella, G
PMID:	10698524

19.
Journal:	Br J Cancer. 2000 May;82(9):1557-60.
Title:	A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma.
Author:	Tanaka, S\|Mori, M\|Mafune, K\|Ohno, S\|Sugimachi, K
PMID:	10789724

20.
Journal:	Br J Cancer. 2000 Oct;83(8):1015-9.
Title:	No SMAD4 hypermethylation in colorectal cancer.
Author:	Roth, S\|Laiho, P\|Salovaara, R\|Launonen, V\|Aaltonen, L A
PMID:	10993648

21.
Journal:	Biochim Biophys Acta. 2000 Oct 18;1502(2):283-96.
Title:	The 18q21 region in colorectal and pancreatic cancer: independent loss of DCC and DPC4 expression.
Author:	Barbera, V M\|Martin, M\|Marinoso, L\|Munne, A\|Carrato, A\|Real, F X\|Fabre, M
PMID:	11040453

22.
Journal:	J Clin Pathol. 2001 Feb;54(2):126-31.
Title:	Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.
Author:	Entius, M M\|Keller, J J\|Westerman, A M\|van Rees, B P\|van Velthuysen, M L\|de Goeij, A F\|Wilson, J H\|Giardiello, F M\|Offerhaus, G J
PMID:	11215281

23.
Journal:	Genes Chromosomes Cancer. 2001 Jul;31(3):240-7.
Title:	Combined copy status of 18q21 genes in colorectal cancer shows frequent retention of SMAD7.
Author:	Boulay, J L\|Mild, G\|Reuter, J\|Lagrange, M\|Terracciano, L\|Lowy, A\|Laffer, U\|Orth, B\|Metzger, U\|Stamm, B\|Martinoli, S\|Herrmann, R\|Rochlitz, C
PMID:	11391794

24.
Journal:	Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. Epub 2001 Jul 31.
Title:	SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.
Author:	Woodford-Richens, K L\|Rowan, A J\|Gorman, P\|Halford, S\|Bicknell, D C\|Wasan, H S\|Roylance, R R\|Bodmer, W F\|Tomlinson, I P
PMID:	11481457

25.
Journal:	J Biol Chem. 2001 Nov 16;276(46):43175-81. Epub 2001 Sep 11.
Title:	Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability.
Author:	Maurice, D\|Pierreux, C E\|Howell, M\|Wilentz, R E\|Owen, M J\|Hill, C S
PMID:	11553622

26.
Journal:	Cancer Res. 2002 Aug 15;62(16):4558-61.
Title:	No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice.
Author:	Takaku, Kazuaki\|Wrana, Jeffrey L\|Robertson, Elizabeth J\|Taketo, Makoto M
PMID:	12183405

27.
Journal:	Genes Dev. 2002 Sep 1;16(17):2264-73.
Title:	Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer.
Author:	Sterner-Kock, Anja\|Thorey, Irmgard S\|Koli, Katri\|Wempe, Frank\|Otte, Jurgen\|Bangsow, Thorsten\|Kuhlmeier, Katharina\|Kirchner, Thomas\|Jin, Shenchu\|Keski-Oja, Jorma\|von Melchner, Harald
PMID:	12208849

28.
Journal:	Cancer Genet Cytogenet. 2002 Jul 15;136(2):129-37.
Title:	High resolution analysis of chromosome 18 alterations in ulcerative colitis-related colorectal cancer.
Author:	Terdiman, Jonathan P\|Aust, Daniela E\|Chang, Cornell G\|Willenbucher, Robert F\|Baretton, Gustavo B\|Waldman, Frederic M
PMID:	12237237

29.
Journal:	Ann Pathol. 2002 Sep;22(4):277-88.
Title:	[Genetic pathways in colorectal cancer: interest for the pathologist].
Author:	Piard, Francoise\|Martin, Laurent\|Chapusot, Caroline\|Ponnelle, Tibor\|Faivre, Jean
PMID:	12410150

30.
Journal:	Genes Chromosomes Cancer. 2003 Mar;36(3):273-82.
Title:	Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene.
Author:	Hohenstein, Peter\|Molenaar, Lia\|Elsinga, Joyce\|Morreau, Hans\|van der Klift, Heleen\|Struijk, Ada\|Jagmohan-Changur, Shantie\|Smits, Ron\|van Kranen, Henk\|van Ommen, Gert-Jan B\|Cornelisse, Cees\|Devilee, Peter\|Fodde, Riccardo
PMID:	12557227

31.
Journal:	Mamm Genome. 2003 Feb;14(2):119-29.
Title:	Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.
Author:	Silverman, Karen A\|Koratkar, Revati A\|Siracusa, Linda D\|Buchberg, Arthur M
PMID:	12584607

32.
Journal:	Int J Cancer. 2003 Apr 20;104(4):446-9.
Title:	SMAD7 is a prognostic marker in patients with colorectal cancer.
Author:	Boulay, Jean-Louis\|Mild, Gabriele\|Lowy, Adam\|Reuter, Juergen\|Lagrange, Magali\|Terracciano, Luigi\|Laffer, Urban\|Herrmann, Richard\|Rochlitz, Christoph
PMID:	12584741

33.
Journal:	Oncogene. 2003 Mar 6;22(9):1317-23.
Title:	TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines.
Author:	Fink, Stephen P\|Mikkola, Debra\|Willson, James K V\|Markowitz, Sanford
PMID:	12618756

34.
Journal:	Biochem Biophys Res Commun. 2003 Jul 11;306(4):799-804.
Title:	Role of Smad4 (DPC4) inactivation in human cancer.
Author:	Miyaki, Michiko\|Kuroki, Toshio
PMID:	12821112

35.
Journal:	J Exp Clin Cancer Res. 2003 Jun;22(2):315-20.
Title:	Mutational analysis of TGF-beta type II receptor, Smad2, Smad3, Smad4, Smad6 and Smad7 genes in colorectal cancer.
Author:	Fukushima, T\|Mashiko, M\|Takita, K\|Otake, T\|Endo, Y\|Sekikawa, K\|Takenoshita, S
PMID:	12866583

36.
Journal:	Cancer J. 2003 Jul-Aug;9(4):302-12.
Title:	Loss of Smad signaling in human colorectal cancer is associated with advanced disease and poor prognosis.
Author:	Xie, Wen\|Rimm, David L\|Lin, Yong\|Shih, Weichung J\|Reiss, Michael
PMID:	12967141

37.
Journal:	Biosci Biotechnol Biochem. 2003 Sep;67(9):2042-4.
Title:	Activin A induces phosphorylation of Smad2 but not complex formation of Smad2 with Smad4 in human colon cancer cell line HT-29.
Author:	Pholnukulkit, Pimara\|Sonoyama, Kei\|Kawabata, Jun
PMID:	14520001

38.
Journal:	Oncogene. 2004 Feb 5;23(5):1021-9.
Title:	Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction.
Author:	Kuang, Chenzhong\|Chen, Yan
PMID:	14647410

39.
Journal:	Biochem J. 2004 Apr 1;379(Pt 1):209-16.
Title:	Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells.
Author:	De Bosscher, Karolien\|Hill, Caroline S\|Nicolas, Francisco J
PMID:	14715079

40.
Journal:	Cancer Sci. 2004 Jan;95(1):12-7.
Title:	Transforming growth factor-beta signaling is differentially inhibited by Smad2D450E and Smad3D407E.
Author:	Kondo, Miki\|Suzuki, Hiroyuki\|Takehara, Kazuhiko\|Miyazono, Kohei\|Kato, Mitsuyasu
PMID:	14720321

41.
Journal:	Cancer Res. 2004 Sep 15;64(18):6402-9.
Title:	alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression.
Author:	Swallow, Carol J\|Partridge, Emily A\|Macmillan, Jennifer C\|Tajirian, Tania\|DiGuglielmo, Gianni M\|Hay, Kazy\|Szweras, Melanie\|Jahnen-Dechent, Willi\|Wrana, Jeff L\|Redston, Mark\|Gallinger, Steven\|Dennis, James W
PMID:	15374947

42.
Journal:	Cancer Res. 2004 Nov 1;64(21):7690-6.
Title:	Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.
Author:	Deacu, Elena\|Mori, Yuriko\|Sato, Fumiaki\|Yin, Jing\|Olaru, Andreea\|Sterian, Anca\|Xu, Yan\|Wang, Suna\|Schulmann, Karsten\|Berki, Agnes\|Kan, Takatsugu\|Abraham, John M\|Meltzer, Stephen J
PMID:	15520171

43.
Journal:	Cancer Res. 2005 Jan 1;65(1):157-65.
Title:	Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.
Author:	Yamagata, Hideo\|Matsuzaki, Koichi\|Mori, Shigeo\|Yoshida, Katsunori\|Tahashi, Yoshiya\|Furukawa, Fukiko\|Sekimoto, Go\|Watanabe, Toshihiko\|Uemura, Yoshiko\|Sakaida, Noriko\|Yoshioka, Kazuhiko\|Kamiyama, Yasuo\|Seki, Toshihito\|Okazaki, Kazuichi
PMID:	15665291

44.
Journal:	World J Surg. 2005 Mar;29(3):306-11.
Title:	TGF-beta signaling in colon cancer cells.
Author:	Li, Fazhi\|Cao, Yanna\|Townsend, Courtney M Jr\|Ko, Tien C
PMID:	15711891

45.
Journal:	Biochem Biophys Res Commun. 2005 Aug 5;333(3):827-32.
Title:	Inhibitory effect of genistein on mouse colon cancer MC-26 cells involved TGF-beta1/Smad pathway.
Author:	Yu, Zengli\|Tang, Yunan\|Hu, Dongsheng\|Li, Juan
PMID:	15963949

46.
Journal:	Oncology. 2005;68(2-3):246-55. Epub 2005 Jul 7.
Title:	Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer.
Author:	Storojeva, Iana\|Boulay, Jean-Louis\|Ballabeni, Pierluigi\|Buess, Martin\|Terracciano, Luigi\|Laffer, Urban\|Mild, Gabriele\|Herrmann, Richard\|Rochlitz, Christoph
PMID:	16015041

47.
Journal:	Mol Cell Biol. 2005 Sep;25(18):8108-25.
Title:	Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
Author:	Levy, Laurence\|Hill, Caroline S
PMID:	16135802

48.
Journal:	Cell Signal. 2006 Jul;18(7):1041-50. Epub 2005 Nov 8.
Title:	Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells.
Author:	Grau, Ana M\|Datta, Pran K\|Zi, Jinghuan\|Halder, Sunil K\|Beauchamp, R Daniel
PMID:	16288847

49.
Journal:	Cancer Lett. 2007 Mar 18;247(2):283-92. Epub 2006 Jul 7.
Title:	Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation.
Author:	Ku, Ja-Lok\|Park, Seok-Hee\|Yoon, Kyong-Ah\|Shin, Young-Kyoung\|Kim, Kyung-Hee\|Choi, Jin-Sung\|Kang, Hio-Chung\|Kim, Il-Jin\|Han, Inn-Oc\|Park, Jae-Gahb
PMID:	16828225

50.
Journal:	J Pathol. 2007 Nov;213(3):257-65.
Title:	Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta.
Author:	Baker, K\|Raut, P\|Jass, J R
PMID:	17893910

51.
Journal:	Cell Oncol. 2008;30(1):1-11.
Title:	Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases.
Author:	Veenendaal, Liesbeth M\|Kranenburg, Onno\|Smakman, Niels\|Klomp, Annemarie\|Borel Rinkes, Inne H M\|van Diest, Paul J
PMID:	18219106

52.
Journal:	Mod Pathol. 2008 Jul;21(7):866-75.
Title:	Expression of Smad2 and Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival.
Author:	Kloth, Judith N\|Kenter, Gemma G\|Spijker, H Siebe\|Uljee, Sandra\|Corver, Willem E\|Jordanova, Ekaterina S\|Fleuren, Gert Jan\|Gorter, Arko
PMID:	18425078

53.
Journal:	Int J Cancer. 2008 Jul 1;123(1):14-21.
Title:	The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.
Author:	Rojas, Andres\|Meherem, Shereen\|Kim, Young-Ho\|Washington, Mary Kay\|Willis, Joseph E\|Markowitz, Sanford D\|Grady, William M
PMID:	18425817

54.
Journal:	Cancer Biol Ther. 2008 Oct;7(10):1694-9. Epub 2008 Oct 22.
Title:	TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells.
Author:	Chow, Jimmy Y C\|Cabral, Jennifer A\|Chang, Jessica\|Carethers, John M
PMID:	18769113

55.
Journal:	Br J Cancer. 2008 Sep 16;99(6):957-65.
Title:	Smad7 induces hepatic metastasis in colorectal cancer.
Author:	Halder, S K\|Rachakonda, G\|Deane, N G\|Datta, P K
PMID:	18781153

56.
Journal:	Int J Biol Markers. 2008 Jul-Sep;23(3):169-75.
Title:	SMAD2 and the relationship of colorectal cancer to inflammatory bowel disease.
Author:	Mahid, S S\|Minor, K S\|Brangers, B C\|Cobbs, G A\|Galandiuk, S
PMID:	18949743

57.
Journal:	BMC Cancer. 2008 Oct 29;8:314.
Title:	Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis.
Author:	Lips, Esther H\|van Eijk, Ronald\|de Graaf, Eelco J R\|Oosting, Jan\|de Miranda, Noel F C C\|Karsten, Tom\|van de Velde, Cornelis J\|Eilers, Paul H C\|Tollenaar, Rob A E M\|van Wezel, Tom\|Morreau, Hans
PMID:	18959792

58.
Journal:	Cancer Res. 2009 Jan 15;69(2):678-86.
Title:	Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.
Author:	Zeng, Qinghua\|Phukan, Sharbani\|Xu, Yanfei\|Sadim, Maureen\|Rosman, Diana S\|Pennison, Michael\|Liao, Jie\|Yang, Guang-Yu\|Huang, Chiang-Ching\|Valle, Laura\|Di Cristofano, Antonio\|de la Chapelle, Albert\|Pasche, Boris
PMID:	19147584

59.
Journal:	Cancer Res. 2009 Jul 1;69(13):5321-30.
Title:	Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
Author:	Matsuzaki, Koichi\|Kitano, Chiaki\|Murata, Miki\|Sekimoto, Go\|Yoshida, Katsunori\|Uemura, Yoshiko\|Seki, Toshihito\|Taketani, Shigeru\|Fujisawa, Jun-ichi\|Okazaki, Kazuichi
PMID:	19531654

60.
Journal:	Pathobiology. 2009;76(4):163-9.
Title:	RUNX3 inhibits cell proliferation and induces apoptosis by TGF-beta-dependent and -independent mechanisms in human colon carcinoma cells.
Author:	Tong, Dan-Dan\|Jiang, Ying\|Li, Ming\|Kong, Dan\|Meng, Xiang-Nin\|Zhao, Yu-Zhen\|Jin, Yan\|Bai, Jing\|Fu, Song-Bin\|Geng, Jing-Shu
PMID:	19571605

61.
Journal:	Cancer Sci. 2009 Nov;100(11):2133-42.
Title:	Promoter-wide analysis of Smad4 binding sites in human epithelial cells.
Author:	Koinuma, Daizo\|Tsutsumi, Shuichi\|Kamimura, Naoko\|Imamura, Takeshi\|Aburatani, Hiroyuki\|Miyazono, Kohei
PMID:	19686287

62.
Journal:	Anat Rec (Hoboken). 2010 Jan;293(1):42-7.
Title:	Transforming growth factor-beta suppressed Id-1 Expression in a smad3-dependent manner in LoVo cells.
Author:	Song, Hongjiang\|Guo, Baoliang\|Zhang, Jianguo\|Song, Chunfang
PMID:	19798702

63.
Journal:	PLoS One. 2010 Jan 26;5(1):e8879.
Title:	Distinct genetic alterations in colorectal cancer.
Author:	Ashktorab, Hassan\|Schaffer, Alejandro A\|Daremipouran, Mohammad\|Smoot, Duane T\|Lee, Edward\|Brim, Hassan
PMID:	20126641

64.
Journal:	J Cell Physiol. 2010 Aug;224(2):398-404.
Title:	Vectorial TGFbeta signaling in polarized intestinal epithelial cells.
Author:	Yakovich, Adam J\|Huang, Qin\|Du, Jianguo\|Jiang, Bo\|Barnard, John A
PMID:	20432436

65.
Journal:	Carcinogenesis. 2010 Sep;31(9):1541-51.
Title:	Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells.
Author:	Ang, Chin Wee\|Nedjadi, Taoufik\|Sheikh, Adnan A\|Tweedle, Elizabeth M\|Tonack, Sarah\|Honap, Sailish\|Jenkins, Rosalind E\|Park, B Kevin\|Schwarte-Waldhoff, Irmgard\|Khattak, Ilyas\|Azadeh, Bahram\|Dodson, Andrew\|Kalirai, Helen\|Neoptolemos, John P\|Rooney, Paul S\|Co
PMID:	20622003

66.
Journal:	Int J Biochem Cell Biol. 2010 Dec;42(12):1964-72.
Title:	Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells.
Author:	Zhang, Yu\|Bao, Yong-Li\|Yang, Mei-Ting\|Wu, Yin\|Yu, Chun-Lei\|Huang, Yan-Xin\|Sun, Ying\|Zheng, Li-Hua\|Li, Yu-Xin
PMID:	20732443

67.
Journal:	Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):57-69.
Title:	Genetic variation in the TGF-beta signaling pathway and colon and rectal cancer risk.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Lundgreen, Abbie\|Wolff, Roger K
PMID:	21068203

68.
Journal:	Cancer. 2011 Sep 15;117(18):4175-83.
Title:	Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Wolff, Roger K\|Caan, Bette J
PMID:	21365634

69.
Journal:	Exp Cell Res. 2011 Jun 10;317(10):1368-81.
Title:	The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.
Author:	Bordonaro, Michael\|Tewari, Shruti\|Atamna, Wafa\|Lazarova, Darina L
PMID:	21473864

70.
Journal:	Mol Carcinog. 2011 May;50(5):359-69.
Title:	Chemopreventive effect of ERbeta-Selective agonist on intestinal tumorigenesis in Apc(Min/+) mice.
Author:	Giroux, Veronique\|Bernatchez, Gerald\|Carrier, Julie C
PMID:	21480389

71.
Journal:	J Transl Med. 2011 Jun 25;9:97.
Title:	Protein kinase CK2alpha is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genes.
Author:	Zou, Jinjin\|Luo, Hesan\|Zeng, Qin\|Dong, Zhongyi\|Wu, Dehua\|Liu, Li
PMID:	21702981

72.
Journal:	Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):781-7.
Title:	Analysis of expression profile of gene encoding proteins of signal cascades activated by insulin-like growth factors in colorectal cancer.
Author:	Nowakowska-Zajdel, E\|Mazurek, U\|Ziolko, E\|Niedworok, E\|Fatyga, E\|Kokot, T\|Muc-Wierzgon, Malgorzata
PMID:	21978709

73.
Journal:	Cancer Res. 2011 Oct 15;71(20):6438-49.
Title:	Enhancement of TGF-beta signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.
Author:	Sharma, Vikas\|Antonacopoulou, Anna G\|Tanaka, Shinya\|Panoutsopoulos, Alexios A\|Bravou, Vasiliki\|Kalofonos, Haralabos P\|Episkopou, Vasso
PMID:	21998011

74.
Journal:	Cancer Sci. 2012 Feb;103(2):317-24.
Title:	Direct inhibition of the transforming growth factor-beta pathway by protein-bound polysaccharide through inactivation of Smad2 signaling.
Author:	Ono, Yoshihiro\|Hayashida, Tetsu\|Konagai, Ayano\|Okazaki, Hiroshi\|Miyao, Kazuhiro\|Kawachi, Shigeyuki\|Tanabe, Minoru\|Shinoda, Masahiro\|Jinno, Hiromitsu\|Hasegawa, Hirotoshi\|Kitajima, Masaki\|Kitagawa, Yuko
PMID:	22034928

75.
Journal:	Int J Mol Med. 2012 May;29(5):906-12.
Title:	Transforming growth factor-beta1 induces glutathione peroxidase-1 and protects from H2O2-induced cell death in colon cancer cells via the Smad2/ERK1/2/HIF-1alpha pathway.
Author:	Huang, Ying\|Fang, Wenfeng\|Wang, Yulei\|Yang, Wancai\|Xiong, Bin
PMID:	22307228

76.
Journal:	Clin Cancer Res. 2012 Jun 1;18(11):3054-70.
Title:	Microarray analysis of colorectal cancer stromal tissue reveals upregulation of two oncogenic miRNA clusters.
Author:	Nishida, Naohiro\|Nagahara, Makoto\|Sato, Tetsuya\|Mimori, Koshi\|Sudo, Tomoya\|Tanaka, Fumiaki\|Shibata, Kohei\|Ishii, Hideshi\|Sugihara, Kenichi\|Doki, Yuichiro\|Mori, Masaki
PMID:	22452939

77.
Journal:	PLoS One. 2012;7(11):e50351.
Title:	Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-beta/endoglin signaling.
Author:	Huang, Feng-Ying\|Mei, Wen-Li\|Li, Yue-Nan\|Tan, Guang-Hong\|Dai, Hao-Fu\|Guo, Jun-Li\|Wang, Hua\|Huang, Yong-Hao\|Zhao, Huan-Ge\|Zhou, Song-Lin\|Lin, Ying-Ying
PMID:	23209720

78.
Journal:	Oncogene. 2013 Sep 19;32(38):4490-9.
Title:	BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor beta (TGF-beta1) in colorectal tumour cells.
Author:	Skeen, V R\|Collard, T J\|Southern, S L\|Greenhough, A\|Hague, A\|Townsend, P A\|Paraskeva, C\|Williams, A C
PMID:	23108401

79.
Journal:	Cancer Res. 2013 Jan 15;73(2):725-35.
Title:	SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.
Author:	Fleming, Nicholas I\|Jorissen, Robert N\|Mouradov, Dmitri\|Christie, Michael\|Sakthianandeswaren, Anuratha\|Palmieri, Michelle\|Day, Fiona\|Li, Shan\|Tsui, Cary\|Lipton, Lara\|Desai, Jayesh\|Jones, Ian T\|McLaughlin, Stephen\|Ward, Robyn L\|Hawkins, Nicholas J\|Ruszkiew
PMID:	23139211

80.
Journal:	Exp Cell Res. 2013 Feb 1;319(3):12-22.
Title:	Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGFbeta1-targeting peptides P17 and P144.
Author:	Zubeldia, Idoia G\|Bleau, Anne-Marie\|Redrado, Miriam\|Serrano, Diego\|Agliano, Alice\|Gil-Puig, Carmen\|Vidal-Vanaclocha, Fernando\|Lecanda, Jon\|Calvo, Alfonso
PMID:	23153552

81.
Journal:	Eur J Cancer Prev. 2013 Sep;22(5):420-4.
Title:	Evaluation of the prognostic value of pSMAD immunohistochemistry in colorectal cancer.
Author:	Voorneveld, Philip W\|Jacobs, Rutger J\|De Miranda, Noel F C C\|Morreau, Hans\|van Noesel, Carel J M\|Offerhaus, G Johan A\|Kodach, Liudmila L\|Hardwick, James C H
PMID:	23426176

82.
Journal:	PLoS One. 2013;8(3):e59918.
Title:	TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis.
Author:	Geng, Liying\|Chaudhuri, Anathbandhu\|Talmon, Geoffrey\|Wisecarver, James L\|Wang, Jing
PMID:	23536895

83.
Journal:	Genet Mol Res. 2013 Apr 10;12(2):1106-18.
Title:	S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Author:	Hussain, Z\|Khan, M I\|Shahid, M\|Almajhdi, F N
PMID:	23661436

84.
Journal:	Mol Cell Biochem. 2013 Nov;383(1-2):179-89.
Title:	APRIL depletion induces cell cycle arrest and apoptosis through blocking TGF-beta1/ERK signaling pathway in human colorectal cancer cells.
Author:	Wang, Feng\|Chen, Lin\|Ni, Hongbin\|Wang, Guihua\|Ding, Weifeng\|Cong, Hui\|Ju, Shaoqing\|Yang, Shumei\|Wang, Huimin
PMID:	23867993

85.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G564-72.
Title:	Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion.
Author:	Swietlicki, Elzbieta A\|Bala, Shashi\|Lu, Jianyun\|Shaker, Anisa\|Kularatna, Gowri\|Levin, Marc S\|Rubin, Deborah C
PMID:	23886856

86.
Journal:	PLoS One. 2014 Jan 10;9(1):e85340.
Title:	High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner.
Author:	Rao, Cui\|Lin, Shan-Li\|Ruan, Wen-Jing\|Wen, Huan\|Wu, Dan-Ju\|Deng, Hong
PMID:	24427302

87.
Journal:	J Natl Cancer Inst. 2014 Apr;106(4):dju043.
Title:	Masking epistasis between MYC and TGF-beta pathways in antiangiogenesis-mediated colon cancer suppression.
Author:	Dews, Michael\|Tan, Grace S\|Hultine, Stacy\|Raman, Pichai\|Choi, Jaewoo\|Duperret, Elizabeth K\|Lawler, Jack\|Bass, Adam\|Thomas-Tikhonenko, Andrei
PMID:	24627270

88.
Journal:	Cancer. 2014 Jul 1;120(13):1948-59.
Title:	Identification of a characteristic copy number alteration profile by high-resolution single nucleotide polymorphism arrays associated with metastatic sporadic colorectal cancer.
Author:	Gonzalez-Gonzalez, Maria\|Fontanillo, Celia\|Abad, Maria M\|Gutierrez, Maria L\|Mota, Ines\|Bengoechea, Oscar\|Santos-Briz, Angel\|Blanco, Oscar\|Fonseca, Emilio\|Ciudad, Juana\|Fuentes, Manuel\|De Las Rivas, Javier\|Alcazar, Jose A\|Garcia, Jacinto\|Munoz-Bellvis, Lui
PMID:	24668684

89.
Journal:	Biomed Res Int. 2014;2014:364134.
Title:	Nodal promotes the self-renewal of human colon cancer stem cells via an autocrine manner through Smad2/3 signaling pathway.
Author:	Gong, Yuehua\|Guo, Ying\|Hai, Yanan\|Yang, Hao\|Liu, Yang\|Yang, Shi\|Zhang, Zhenzhen\|Ma, Meng\|Liu, Linhong\|Li, Zheng\|He, Zuping
PMID:	24696849

90.
Journal:	Chem Biol Interact. 2014 Jun 25;217:1-8.
Title:	N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells.
Author:	Liu, Ling-Yu\|Huang, Wei-Jan\|Ho, Feng-Ming\|Lin, Ren-Jye\|Lin, Shyr-Yi\|Suk, Fat-Moon\|Liang, Yu-Chih
PMID:	24727557

91.
Journal:	Epigenomics. 2014 Apr;6(2):179-91.
Title:	DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes.
Author:	Farkas, Sanja A\|Vymetalkova, Veronika\|Vodickova, Ludmila\|Vodicka, Pavel\|Nilsson, Torbjorn K
PMID:	24811787

92.
Journal:	Oncol Rep. 2014 Sep;32(3):1124-32.
Title:	S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-beta signaling pathway in cancer cells.
Author:	Tong, Dandan\|Qu, Hui\|Meng, Xiangning\|Jiang, Yang\|Liu, Duanyang\|Ye, Shengqian\|Chen, He\|Jin, Yan\|Fu, Songbin\|Geng, Jingshu
PMID:	24970681

93.
Journal:	PLoS One. 2014 Aug 28;9(8):e105991.
Title:	Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2.
Author:	Bao, Yonghua\|Chen, Zhiguo\|Guo, Yongchen\|Feng, Yansheng\|Li, Zexin\|Han, Wenliang\|Wang, Jianguo\|Zhao, Weixing\|Jiao, Yunjuan\|Li, Kai\|Wang, Qian\|Wang, Jiaqi\|Zhang, Huijuan\|Wang, Liang\|Yang, Wancai
PMID:	25166914

94.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G749-59.
Title:	PDGF receptor-alpha promotes TGF-beta signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-beta receptors.
Author:	Liu, Chunsheng\|Li, Jiachu\|Xiang, Xiaoyu\|Guo, Luyang\|Tu, Kangsheng\|Liu, Qinghua\|Shah, Vijay H\|Kang, Ningling
PMID:	25169976

95.
Journal:	PLoS One. 2014 Sep 19;9(9):e107514.
Title:	Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.
Author:	Buhrmann, Constanze\|Kraehe, Patricia\|Lueders, Cora\|Shayan, Parviz\|Goel, Ajay\|Shakibaei, Mehdi
PMID:	25238234

96.
Journal:	Int J Oncol. 2015 Feb;46(2):685-90.
Title:	Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-beta1/ZEB/miR-200 signaling network.
Author:	Shen, Aling\|Lin, Wei\|Chen, Youqin\|Liu, Liya\|Chen, Hongwei\|Zhuang, Qunchuan\|Lin, Jiumao\|Sferra, Thomas J\|Peng, Jun
PMID:	25422078

97.
Journal:	Oncol Rep. 2015 Apr;33(4):1922-8.
Title:	Pien Tze Huang inhibits liver metastasis by targeting TGF-beta signaling in an orthotopic model of colorectal cancer.
Author:	Lin, Wei\|Zhuang, Qunchuan\|Zheng, Liangpu\|Cao, Zhiyun\|Shen, Aling\|Li, Qiongyu\|Fu, Caixuan\|Feng, Jianyu\|Peng, Jun
PMID:	25653118

98.
Journal:	Gastroenterology. 2015 Jun;148(7):1427-37.e8.
Title:	Transforming Growth Factor beta Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.
Author:	de Miranda, Noel F C C\|van Dinther, Maarten\|van den Akker, Brendy E W M\|van Wezel, Tom\|ten Dijke, Peter\|Morreau, Hans
PMID:	25736321

99.
Journal:	Stem Cell Res Ther. 2015 Apr 13;6:71.
Title:	Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer.
Author:	Tang, Rui-jing\|Shen, Su-nan\|Zhao, Xiao-yin\|Nie, Yun-zhong\|Xu, Yu-jun\|Ren, Jing\|Lv, Ming-ming\|Hou, Ya-yi\|Wang, Ting-ting
PMID:	25889203

100.
Journal:	J Crohns Colitis. 2015 Jul;9(7):565-74.
Title:	Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
Author:	Suzuki, Ryo\|Fukui, Toshiro\|Kishimoto, Masanobu\|Miyamoto, Sachi\|Takahashi, Yu\|Takeo, Masahiro\|Mitsuyama, Toshiyuki\|Sakaguchi, Yutaku\|Uchida, Kazushige\|Nishio, Akiyoshi\|Okazaki, Kazuichi
PMID:	25908723

101.
Journal:	Int J Biochem Cell Biol. 2015 Jul;64:202-11.
Title:	Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-beta/Smad2/3 signaling.
Author:	Zhang, Lichao\|Li, Zongwei\|Fan, Yongsheng\|Li, Hanqing\|Li, Zhouyu\|Li, Yaoping
PMID:	25934251

102.
Journal:	J Mol Biol. 2015 Oct 23;427(21):3407-15.
Title:	Crosstalk between Hippo and TGFbeta: Subcellular Localization of YAP/TAZ/Smad Complexes.
Author:	Grannas, Karin\|Arngarden, Linda\|Lonn, Peter\|Mazurkiewicz, Magdalena\|Blokzijl, Andries\|Zieba, Agata\|Soderberg, Ola
PMID:	25937570

103.
Journal:	PLoS One. 2015 May 14;10(5):e0126670.
Title:	Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.
Author:	Kim, Richard\|Schell, Michael J\|Teer, Jamie K\|Greenawalt, Danielle M\|Yang, Mingli\|Yeatman, Timothy J
PMID:	25974029

104.
Journal:	Oncotarget. 2015 Aug 14;6(23):19735-46.
Title:	Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy.
Author:	Zhai, Haiyan\|Fesler, Andrew\|Ba, Yufeng\|Wu, Song\|Ju, Jingfang
PMID:	25980495

105.
Journal:	Gastroenterol Hepatol Bed Bench. 2015 Summer;8(3):215-24.
Title:	Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer.
Author:	Zamanian-Azodi, Mona\|Rezaei-Tavirani, Mostafa\|Rahmati-Rad, Sara\|Hasanzadeh, Hadi\|Rezaei Tavirani, Majid\|Seyyedi, Samaneh Sadat
PMID:	26328044

106.
Journal:	Int J Mol Sci. 2015 Sep 7;16(9):21342-62.
Title:	New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding.
Author:	Foca, Annalia\|Sanguigno, Luca\|Foca, Giuseppina\|Strizzi, Luigi\|Iannitti, Roberta\|Palumbo, Rosanna\|Hendrix, Mary J C\|Leonardi, Antonio\|Ruvo, Menotti\|Sandomenico, Annamaria
PMID:	26370966

107.
Journal:	Oncotarget. 2016 Jan 5;7(1):860-72.
Title:	GDF15 promotes EMT and metastasis in colorectal cancer.
Author:	Li, Chen\|Wang, Jingyu\|Kong, Jianlu\|Tang, Jinlong\|Wu, Yihua\|Xu, Enping\|Zhang, Honghe\|Lai, Maode
PMID:	26497212

108.
Journal:	Mol Med Rep. 2016 Jan;13(1):909-14.
Title:	Modulation of transforming growth factorbeta signaling transducers in colon adenocarcinoma cells induced by staphylococcal enterotoxin B.
Author:	Akbari, Abolfazl\|Mobini, Gholam Reza\|Maghsoudi, Reza\|Akhtari, Javad\|Faghihloo, Ebrahim\|Farahnejad, Zohreh
PMID:	26647993

109.
Journal:	Int Immunopharmacol. 2016 Jun;35:287-293.
Title:	Tolfenamic acid downregulates beta-catenin in colon cancer.
Author:	Ha, Taekyu\|Lou, Zhiyuan\|Baek, Seung Joon\|Lee, Seong-Ho
PMID:	27089389

110.
Journal:	J Biol Chem. 2016 Aug 12;291(33):17405-16.
Title:	Transforming Growth Factor beta Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer.
Author:	Zhang, Yang\|Zhang, Yi\|Geng, Liying\|Yi, Haowei\|Huo, Wei\|Talmon, Geoffrey\|Kim, Yeong C\|Wang, San Ming\|Wang, Jing
PMID:	27330076

111.
Journal:	Oncotarget. 2016 Sep 20;7(38):61562-61574.
Title:	Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4.
Author:	Yang, Lei\|Hu, Shusheng\|Tan, Jinjing\|Zhang, Xiaojing\|Yuan, Wen\|Wang, Qian\|Xu, Lingling\|Liu, Jian\|Liu, Zheng\|Jia, Yanjun\|Huang, Xiaoxi
PMID:	27528036

112.
Journal:	Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title:	Genomic characterization of liver metastases from colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Corchete, Luis Antonio\|Gutierrez, Maria Laura\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria\|Bengoechea, Oscar\|Ferminan, Encarna\|Anduaga, Maria Fernanda\|Del Carmen, Sofia\|Iglesias, Manuel\|Esteban, Carmen\|Angoso, Maria\|Alcazar, Jose Ant
PMID:	27662660

113.
Journal:	Neuroendocrinology. 2017;104(3):302-312.
Title:	Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains.
Author:	Nieser, Maike\|Henopp, Tobias\|Brix, Joachim\|Stoss, Laura\|Sitek, Barbara\|Naboulsi, Wael\|Anlauf, Martin\|Schlitter, Anna M\|Kloppel, Gunter\|Gress, Thomas\|Moll, Roland\|Bartsch, Detlef K\|Heverhagen, Anna E\|Knoefel, Wolfram T\|Kaemmerer, Daniel\|Haybaeck, Johannes\|
PMID:	27222126

114.
Journal:	J Recept Signal Transduct Res. 2017 Apr;37(2):189-199.
Title:	Cholest-4-en-3-one attenuates TGF-beta responsiveness by inducing TGF-beta receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells.
Author:	Chen, Chun-Lin\|Wu, Deng-Chyang\|Liu, Min-Yun\|Lin, Ming-Wei\|Huang, Hung-Tu\|Huang, Yaw-Bin\|Chen, Li-Chai\|Chen, Yu-Yu\|Chen, Jih-Jung\|Yang, Pei-Hua\|Kao, Yu-Chen\|Chen, Pei-Yu
PMID:	27401208

115.
Journal:	Oncol Rep. 2017 Jan;37(1):115-122.
Title:	TGF-beta1 induces PGP9.5 expression in CAFs to promote the growth of colorectal cancer cells.
Author:	Wen, Wei\|Liu, Ge\|Jin, Ke\|Hu, Xiang
PMID:	27840994

116.
Journal:	Toxicol Lett. 2017 Jan 4;265:53-60.
Title:	Microcystin-LR promotes epithelial-mesenchymal transition in colorectal cancer cells through PI3-K/AKT and SMAD2.
Author:	Ren, Yan\|Yang, Mengli\|Chen, Meng\|Zhu, Qiangqiang\|Zhou, Lihua\|Qin, Wei\|Wang, Ting
PMID:	27856280

117.
Journal:	BMC Cancer. 2017 Jan 3;17(1):4.
Title:	Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration.
Author:	Al-Khayal, Khayal\|Alafeefy, Ahmed\|Vaali-Mohammed, Mansoor-Ali\|Mahmood, Amer\|Zubaidi, Ahmed\|Al-Obeed, Omar\|Khan, Zahid\|Abdulla, Maha\|Ahmad, Rehan
PMID:	28049506

118.
Journal:	Int J Mol Sci. 2017 Jan 19;18(1). pii: ijms18010197.
Title:	Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Author:	Marmol, Ines\|Sanchez-de-Diego, Cristina\|Pradilla Dieste, Alberto\|Cerrada, Elena\|Rodriguez Yoldi, Maria Jesus
PMID:	28106826

119.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

120.
Journal:	Biomed Res Int. 2017;2017:2613198.
Title:	JianPi JieDu Recipe Inhibits Epithelial-to-Mesenchymal Transition in Colorectal Cancer through TGF-beta/Smad Mediated Snail/E-Cadherin Expression.
Author:	Liu, Xuan\|Ji, Qing\|Deng, Wanli\|Chai, Ni\|Feng, Yuanyuan\|Zhou, Lihong\|Sui, Hua\|Li, Chunpu\|Sun, Xiaoting\|Li, Qi
PMID:	28299321

121.
Journal:	Anat Rec (Hoboken). 2017 Sep;300(9):1560-1569.
Title:	Smad4 Inhibits VEGF-A and VEGF-C Expressions via Enhancing Smad3 Phosphorylation in Colon Cancer.
Author:	Li, Xuemei\|Li, Xinlei\|Lv, Xiaohong\|Xiao, Jianbing\|Liu, Baoquan\|Zhang, Yafang
PMID:	28445620

122.
Journal:	EBioMedicine. 2017 Jun;20:39-49.
Title:	A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.
Author:	Viel, Alessandra\|Bruselles, Alessandro\|Meccia, Ettore\|Fornasarig, Mara\|Quaia, Michele\|Canzonieri, Vincenzo\|Policicchio, Eleonora\|Urso, Emanuele Damiano\|Agostini, Marco\|Genuardi, Maurizio\|Lucci-Cordisco, Emanuela\|Venesio, Tiziana\|Martayan, Aline\|Diodoro, M
PMID:	28551381

123.
Journal:	BMC Gastroenterol. 2017 Jun 7;17(1):73.
Title:	Anti-fibrogenic effect of PPAR-gamma agonists in human intestinal myofibroblasts.
Author:	Koo, Jun Bon\|Nam, Myeong-Ok\|Jung, Younshin\|Yoo, Jongman\|Kim, Duk Hwan\|Kim, Gwangil\|Shin, Sung Jae\|Lee, Kee Myung\|Hahm, Ki Baik\|Kim, Jong Woo\|Hong, Sung Pyo\|Lee, Kwang Jae\|Yoo, Jun Hwan
PMID:	28592228

124.
Journal:	Hum Pathol. 2017 Aug;66:34-39.
Title:	Significance of positive and inhibitory regulators in the TGF-beta signaling pathway in colorectal cancers.
Author:	Coates, Ryan F\|Gardner, Juli-Anne\|Gao, Yuan\|Cortright, Valerie M\|Mitchell, Jeannette M\|Ashikaga, Takamaru\|Skelly, Joan\|Yang, Michelle X
PMID:	28601657

125.
Journal:	Tumour Biol. 2017 Jul;39(7):1010428317714899.
Title:	Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing.
Author:	Liu, Jixi\|Liu, Fang\|Li, Xiaoou\|Song, Xin\|Zhou, Lei\|Jie, Jianzheng
PMID:	28714374

126.
Journal:	J Cancer. 2017 Jul 21;8(12):2336-2345.
Title:	Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance.
Author:	Pi, Leiming\|Zhu, Gangcai\|She, Li\|Wei, Ming\|Liu, Guancheng\|Chen, Changhan\|Hu, Di\|Peng, Fusen\|Tan, Haolei\|Liu, Yong\|Huang, Donghai\|Tian, Yongquan\|Zhang, Xin
PMID:	28819438

127.
Journal:	Mol Carcinog. 2017 Dec;56(12):2692-2705.
Title:	Down-regulation of aquaporin 5-mediated epithelial-mesenchymal transition and anti-metastatic effect by natural product Cairicoside E in colorectal cancer.
Author:	Chen, Chen\|Ma, Ting\|Zhang, Chao\|Zhang, Hao\|Bai, Lijuan\|Kong, Lingyi\|Luo, Jianguang
PMID:	28833571

128.
Journal:	Oncotarget. 2017 Sep 2;8(41):69386-69397.
Title:	Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition.
Author:	Kim, Joong Sun\|Han, Na-Kyung\|Kim, Sung-Ho\|Lee, Hae-June
PMID:	29050211

129.
Journal:	Am J Pathol. 2018 Jan;188(1):204-215.
Title:	Chorionic Gonadotropin-beta Modulates Epithelial-Mesenchymal Transition in Colorectal Carcinoma Metastasis.
Author:	Kawamata, Futoshi\|Nishihara, Hiroshi\|Homma, Shigenori\|Kato, Yasutaka\|Tsuda, Masumi\|Konishi, Yuji\|Wang, Lei\|Kohsaka, Shinji\|Liu, Cheng\|Yoshida, Tadashi\|Tanino, Mishie\|Tanaka, Shinya\|Kawamura, Hideki\|Kamiyama, Toshiya\|Taketomi, Akinobu
PMID:	29037859

130.
Journal:	Cancer Biol Ther. 2018 Feb 1;19(2):105-112.
Title:	Multispectral imaging reveals hyper active TGF-beta signaling in colorectal cancer.
Author:	Yang, Lei\|Liu, Zheng\|Tan, Jinjing\|Dong, Hongwei\|Zhang, Xiaojing
PMID:	29219668

131.
Journal:	Medicine (Baltimore). 2018 Feb;97(7):e9738.
Title:	Identification of gene expression models for laryngeal squamous cell carcinoma using co-expression network analysis.
Author:	Yang, Chun-Wei\|Wang, Shu-Fang\|Yang, Xiang-Li\|Wang, Lin\|Niu, Lin\|Liu, Ji-Xiang
PMID:	29443735

132.
Journal:	Cell Death Dis. 2018 Feb 15;9(3):263.
Title:	NIT1 suppresses tumour proliferation by activating the TGFbeta1-Smad2/3 signalling pathway in colorectal cancer.
Author:	Lin, Chun\|Zhang, Jianming\|Lu, Yanxia\|Li, Xiaomin\|Zhang, Wenjuan\|Zhang, Wei\|Lin, Weihao\|Zheng, Lin\|Li, Xuenong
PMID:	29449642

133.
Journal:	Sci Rep. 2018 Feb 16;8(1):3161.
Title:	Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations.
Author:	Druliner, Brooke R\|Wang, Panwen\|Bae, Taejeong\|Baheti, Saurabh\|Slettedahl, Seth\|Mahoney, Douglas\|Vasmatzis, Nikolaos\|Xu, Hang\|Kim, Minsoo\|Bockol, Matthew\|O'Brien, Daniel\|Grill, Diane\|Warner, Nathaniel\|Munoz-Gomez, Miguel\|Kossick, Kimberlee\|Johnson, Ruth\|Mo
PMID:	29453410

134.
Journal:	Exp Ther Med. 2018 Apr;15(4):3495-3500.
Title:	GDF11/BMP11 as a novel tumor marker for liver cancer.
Author:	Zhang, Yong-Hui\|Pan, Lian-Hong\|Pang, Yi\|Yang, Jin-Xin\|Lv, Meng-Jia\|Liu, Feng\|Qu, Xue-Feng\|Chen, Xin-Xin\|Gong, Hua-Jun\|Liu, Dan\|Wei, Yong
PMID:	29545874

135.
Journal:	J Biol Chem. 2018 May 25;293(21):8242-8254.
Title:	TGFbeta and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells.
Author:	Leiphrakpam, Premila D\|Brattain, Michael G\|Black, Jennifer D\|Wang, Jing
PMID:	29599290

136.
Journal:	Cancer Res Treat. 2018 Apr 25. pii: crt.2017.613.
Title:	Tumor-Associated Macrophages Derived TGF-betaInduced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells through Smad2,3-4/Snail Signaling Pathway.
Author:	Cai, Jianhui\|Xia, Limin\|Li, Jinlei\|Ni, Shichang\|Song, Huayu\|Wu, Xiangbin
PMID:	29690747

137.
Journal:	Cell Death Dis. 2018 May 29;9(6):654.
Title:	FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway.
Author:	Gu, Chuansha\|Wang, Xiaoyan\|Long, Ting\|Wang, Xia\|Zhong, Yan\|Ma, Yidan\|Hu, Zhiyan\|Li, Zuguo
PMID:	29844309

138.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

139.
Journal:	Clin Cancer Res. 2018 Jul 2. pii: 1078-0432.CCR-18-0630.
Title:	Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.
Author:	Hirsch, Daniela\|Wangsa, Darawalee\|Zhu, Yuelin J\|Hu, Yue\|Edelman, Daniel C\|Meltzer, Paul S\|Heselmeyer-Haddad, Kerstin\|Ott, Claudia\|Kienle, Peter\|Galata, Christian\|Horisberger, Karoline\|Ried, Thomas\|Gaiser, Timo
PMID:	29967250

140.
Journal:	Front Immunol. 2018 Jun 20;9:1407.
Title:	Transforming Growth Factor-beta1/Smad7 in Intestinal Immunity, Inflammation, and Cancer.
Author:	Troncone, Edoardo\|Marafini, Irene\|Stolfi, Carmine\|Monteleone, Giovanni
PMID:	29973939

141.
Journal:	Epigenomics. 2018 Sep;10(9):1215-1228.
Title:	Screening key long non-coding RNAs in early-stage colon adenocarcinoma by RNA-sequencing.
Author:	Liu, Ji-Xi\|Li, Wen\|Li, Jing-Tao\|Liu, Fang\|Zhou, Lei
PMID:	30182733