Primary Site >> Colorectal Cancer

Gene >> SMAD1

Journal: Gut. 1999 Sep;45(3):406-8.
Title: Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome.
Author: Bevan, S|Woodford-Richens, K|Rozen, P|Eng, C|Young, J|Dunlop, M|Neale, K|Phillips, R|Markie, D|Rodriguez-Bigas, M|Leggett, B|Sheridan, E|Hodgson, S|Iwama, T|Eccles, D|Bodmer, W|Houlston, R|Tomlinson, I
PMID: 10446110
Journal: Int J Cancer. 1999 Jul 19;82(2):197-202.
Title: Expression of Smad proteins in human colorectal cancer.
Author: Korchynskyi, O|Landstrom, M|Stoika, R|Funa, K|Heldin, C H|ten Dijke, P|Souchelnytskyi, S
PMID: 10389752
Journal: Gastroenterology. 2004 Jan;126(1):111-21.
Title: Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon.
Author: Hardwick, James C H|Van Den Brink, Gijs R|Bleuming, Sylvia A|Ballester, Isabel|Van Den Brande, Jan M H|Keller, Josbert J|Offerhaus, G Johan A|Van Deventer, Sander J H|Peppelenbosch, Maikel P
PMID: 14699493
Journal: Am J Physiol Gastrointest Liver Physiol. 2006 Jul;291(1):G135-45.
Title: Bone morphogenetic protein signaling and growth suppression in colon cancer.
Author: Beck, Stayce E|Jung, Barbara H|Fiorino, Antonio|Gomez, Jessica|Rosario, Eunice Del|Cabrera, Betty L|Huang, Sherry C|Chow, Jimmy Y C|Carethers, John M
PMID: 16769811
Journal: Cell Signal. 2007 Jul;19(7):1465-72. Epub 2007 Jan 24.
Title: BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK.
Author: Beck, Stayce E|Jung, Barbara H|Del Rosario, Eunice|Gomez, Jessica|Carethers, John M
PMID: 17317101
Journal: Cancer. 2008 Jan 15;112(2):300-6.
Title: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer.
Author: Kodach, Liudmila L|Bleuming, Sylvia A|Musler, Alex R|Peppelenbosch, Maikel P|Hommes, Daniel W|van den Brink, Gijs R|van Noesel, Carel J M|Offerhaus, G Johan A|Hardwick, James C H
PMID: 18008360
Journal: Cancer Res. 2008 Apr 1;68(7):2250-8.
Title: Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.
Author: Gautschi, Oliver|Tepper, Clifford G|Purnell, Phillip R|Izumiya, Yoshihiro|Evans, Christopher P|Green, Tim P|Desprez, Pierre Y|Lara, Primo N|Gandara, David R|Mack, Philip C|Kung, Hsing-Jien
PMID: 18381431
Journal: Br J Pharmacol. 2008 Jun;154(3):632-8.
Title: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.
Author: Wu, W K K|Sung, J J Y|Wu, Y C|Li, Z J|Yu, L|Cho, C H
PMID: 18414391
Journal: Blood. 2010 Apr 15;115(15):3136-45.
Title: Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.
Author: Lee, Dae-Hoon|Zhou, Li-Juan|Zhou, Zheng|Xie, Jian-Xin|Jung, Ji-Ung|Liu, Yu|Xi, Cai-Xia|Mei, Lin|Xiong, Wen-Cheng
PMID: 20065295
Journal: Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):57-69.
Title: Genetic variation in the TGF-beta signaling pathway and colon and rectal cancer risk.
Author: Slattery, Martha L|Herrick, Jennifer S|Lundgreen, Abbie|Wolff, Roger K
PMID: 21068203
Journal: Cancer. 2011 Sep 15;117(18):4175-83.
Title: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K|Caan, Bette J
PMID: 21365634
Journal: PLoS One. 2012;7(11):e50351.
Title: Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-beta/endoglin signaling.
Author: Huang, Feng-Ying|Mei, Wen-Li|Li, Yue-Nan|Tan, Guang-Hong|Dai, Hao-Fu|Guo, Jun-Li|Wang, Hua|Huang, Yong-Hao|Zhao, Huan-Ge|Zhou, Song-Lin|Lin, Ying-Ying
PMID: 23209720
Journal: Exp Cell Res. 2013 Feb 1;319(3):12-22.
Title: Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGFbeta1-targeting peptides P17 and P144.
Author: Zubeldia, Idoia G|Bleau, Anne-Marie|Redrado, Miriam|Serrano, Diego|Agliano, Alice|Gil-Puig, Carmen|Vidal-Vanaclocha, Fernando|Lecanda, Jon|Calvo, Alfonso
PMID: 23153552
Journal: Eur J Cancer Prev. 2013 Sep;22(5):420-4.
Title: Evaluation of the prognostic value of pSMAD immunohistochemistry in colorectal cancer.
Author: Voorneveld, Philip W|Jacobs, Rutger J|De Miranda, Noel F C C|Morreau, Hans|van Noesel, Carel J M|Offerhaus, G Johan A|Kodach, Liudmila L|Hardwick, James C H
PMID: 23426176
Journal: Biol Reprod. 2014 Oct;91(4):100.
Title: Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line.
Author: Mansouri-Attia, Nadera|James, Rebecca|Ligon, Alysse|Li, Xiaohui|Pangas, Stephanie A
PMID: 25165122
Journal: Oncogene. 2015 Apr 9;34(15):1968-78.
Title: MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling.
Author: Xiao, F|Qiu, H|Cui, H|Ni, X|Li, J|Liao, W|Lu, L|Ding, K
PMID: 24882581
Journal: J Mol Cell Biol. 2015 Apr;7(2):105-18.
Title: P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers.
Author: Ruan, Xinsen|Zuo, Qiao|Jia, Hao|Chau, Jenny|Lin, Jinlin|Ao, Junping|Xia, Xuechun|Liu, Huijuan|Habib, Samy L|Fu, Chuangang|Li, Baojie
PMID: 25757624
Journal: Oncotarget. 2015 Aug 21;6(24):20540-54.
Title: Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.
Author: Shi, Ying|Chen, Guo-Bin|Huang, Xiao-Xiao|Xiao, Chuan-Xing|Wang, Huan-Huan|Li, Ye-Sen|Zhang, Jin-Fang|Li, Shao|Xia, Yin|Ren, Jian-Lin|Guleng, Bayasi
PMID: 26029998
Journal: Tumour Biol. 2015 Dec;36(12):9475-86.
Title: BMP-2 induces motility and invasiveness by promoting colon cancer stemness through STAT3 activation.
Author: Kim, Bo Ram|Oh, Sang Cheul|Lee, Dae-Hee|Kim, Jung Lim|Lee, Suk Young|Kang, Myoung Hee|Lee, Sun Il|Kang, Sanghee|Joung, Sung Yup|Min, Byung Wook
PMID: 26124007
Journal: Oncol Rep. 2016 May;35(5):2691-8.
Title: Oridonin inhibits the proliferation of human colon cancer cells by upregulating BMP7 to activate p38 MAPK.
Author: Ren, Chun-Mei|Li, Yang|Chen, Qian-Zhao|Zeng, Yu-Hua|Shao, Ying|Wu, Qiu-Xiang|Yuan, Shuang-Xue|Yang, Jun-Qin|Yu, Yu|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 26986967
Journal: J Neurosci. 2016 May 25;36(21):5833-49.
Title: Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.
Author: Huang, Zhihui|Sun, Dong|Hu, Jin-Xia|Tang, Fu-Lei|Lee, Dae-Hoon|Wang, Ying|Hu, Guoqing|Zhu, Xiao-Juan|Zhou, Jiliang|Mei, Lin|Xiong, Wen-Cheng
PMID: 27225772
Journal: Oncotarget. 2017 Feb 14;8(7):11489-11506.
Title: Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.
Author: Sun, Jian|Liu, Xuan|Gao, Hong|Zhang, Long|Ji, Qing|Wang, Ziyuan|Zhou, Lihong|Wang, Yan|Sui, Hua|Fan, Zhongze|Li, Qi
PMID: 28009989
Journal: BMC Genomics. 2017 May 30;18(1):421.
Title: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author: Cong, Wang|Meng, Xianglian|Li, Jin|Zhang, Qiushi|Chen, Feng|Liu, Wenjie|Wang, Ying|Cheng, Sipu|Yao, Xiaohui|Yan, Jingwen|Kim, Sungeun|Saykin, Andrew J|Liang, Hong|Shen, Li
PMID: 28558704
Journal: Int J Oncol. 2017 Sep;51(3):907-917.
Title: BMP7 mediates the anticancer effect of honokiol by upregulating p53 in HCT116 cells.
Author: Liu, Rong-Xing|Ren, Wen-Yan|Ma, Yan|Liao, Yun-Peng|Wang, Han|Zhu, Jia-Hui|Jiang, Hai-Tao|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 28731124
Journal: Oncotarget. 2017 Nov 30;8(66):110415-110425.
Title: Smad1 promotes colorectal cancer cell migration through Ajuba transactivation.
Author: Yang, Daming|Hou, Tieying|Li, Lei|Chu, Yimin|Zhou, Fengli|Xu, Ying|Hou, Xinyu|Song, Huan|Zhu, Kai|Hou, Zhaoyuan|Peng, Haixia|Jia, Hao
PMID: 29299158
Journal: Cancer Biol Ther. 2018 Feb 1;19(2):105-112.
Title: Multispectral imaging reveals hyper active TGF-beta signaling in colorectal cancer.
Author: Yang, Lei|Liu, Zheng|Tan, Jinjing|Dong, Hongwei|Zhang, Xiaojing
PMID: 29219668
Journal: Int J Oncol. 2018 Nov;53(5):2091-2101.
Title: Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.
Author: Liu, Rong-Xing|Ma, Yan|Hu, Xue-Lian|Ren, Wen-Yan|Liao, Yun-Peng|Wang, Han|Zhu, Jia-Hui|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 30132514
Journal: Int J Oncol. 2018 Nov;53(5):2091-2101.
Title: Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.
Author: Liu, Rong-Xing|Ma, Yan|Hu, Xue-Lian|Ren, Wen-Yan|Liao, Yun-Peng|Wang, Han|Zhu, Jia-Hui|Wu, Ke|He, Bai-Cheng|Sun, Wen-Juan
PMID: 30132516