Primary Site >> Colorectal Cancer

Gene >> SMAD1

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Ref: Expression of Smad proteins in human colorectal cancer.
PMID: 10389752
Ref: Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome.
PMID: 10446110
Ref: Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon.
PMID: 14699493
Ref: Bone morphogenetic protein signaling and growth suppression in colon cancer.
PMID: 16769811
Ref: BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK.
PMID: 17317101
Ref: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer.
PMID: 18008360
Ref: Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.
PMID: 18381431
Ref: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.
PMID: 18414391
Ref: Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.
PMID: 20065295
Ref: Genetic variation in the TGF-beta signaling pathway and colon and rectal cancer risk.
PMID: 21068203
Ref: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer.
PMID: 21365634
Ref: Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-beta/endoglin signaling.
PMID: 23209720
Ref: Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGFbeta1-targeting peptides P17 and P144.
PMID: 23153552
Ref: Evaluation of the prognostic value of pSMAD immunohistochemistry in colorectal cancer.
PMID: 23426176
Ref: Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line.
PMID: 25165122
Ref: MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling.
PMID: 24882581
Ref: P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers.
PMID: 25757624
Ref: Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.
PMID: 26029998
Ref: BMP-2 induces motility and invasiveness by promoting colon cancer stemness through STAT3 activation.
PMID: 26124007
Ref: Oridonin inhibits the proliferation of human colon cancer cells by upregulating BMP7 to activate p38 MAPK.
PMID: 26986967
Ref: Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.
PMID: 27225772
Ref: Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.
PMID: 28009989
Ref: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
PMID: 28558704
Ref: BMP7 mediates the anticancer effect of honokiol by upregulating p53 in HCT116 cells.
PMID: 28731124
Ref: Smad1 promotes colorectal cancer cell migration through Ajuba transactivation.
PMID: 29299158
Ref: Multispectral imaging reveals hyper active TGF-beta signaling in colorectal cancer.
PMID: 29219668
Ref: Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.
PMID: 30132514
Ref: Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.
PMID: 30132516