Primary Site >> Colorectal Cancer
Gene >> SLC5A8
| 1. | |||||||||||
| Journal: | Biotherapy. 1993;6(1):41-9. | ||||||||||
| Title: | The therapeutic effect of OK-432-combined adoptive immunotherapy against liver metastases from gastric or colorectal cancers. | ||||||||||
| Author: | Satoh, K|Kan, N|Okino, T|Mise, K|Yamasaki, S|Harada, T|Hori, T|Ohgaki, K|Tobe, T | ||||||||||
| PMID: | 8507544 | ||||||||||
| 2. | |||||||||||
| Journal: | Russ J Immunol. 1997 Dec;2(3-4):167-176. | ||||||||||
| Title: | IL-2-Activated Killer Cells and Native Cytokines in Treatment of Patients with Advanced Cancer. | ||||||||||
| Author: | Ostanin, Alexander A.|Chernykh, Helena R.|Leplina, Olga Y.|Shevela, Ekaterina Ya.|Niconov, Sergey D.|Kozlov, Vladimir A. | ||||||||||
| PMID: | 12687071 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 1998 Oct 29;78(3):301-5. | ||||||||||
| Title: | Expression of signal transducing T-cell receptor zeta molecules after adoptive immunotherapy in patients with gastric and colon cancer. | ||||||||||
| Author: | Kono, K|Ichihara, F|Iizuka, H|Sekikawa, T|Matsumoto, Y | ||||||||||
| PMID: | 9766562 | ||||||||||
| 4. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8412-7. Epub 2003 Jun 26. | ||||||||||
| Title: | SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. | ||||||||||
| Author: | Li, Hui|Myeroff, Lois|Smiraglia, Dominic|Romero, Michael F|Pretlow, Theresa P|Kasturi, Lakshmi|Lutterbaugh, James|Rerko, Ronald M|Casey, Graham|Issa, Jean-Pierre|Willis, Joseph|Willson, James K V|Plass, Christoph|Markowitz, Sanford D | ||||||||||
| PMID: | 12829793 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2004 Apr 2;279(14):13293-6. Epub 2004 Feb 13. | ||||||||||
| Title: | Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids. | ||||||||||
| Author: | Miyauchi, Seiji|Gopal, Elangovan|Fei, You-Jun|Ganapathy, Vadivel | ||||||||||
| PMID: | 14966140 | ||||||||||
| 6. | |||||||||||
| Journal: | J Physiol. 2004 Jun 15;557(Pt 3):719-31. Epub 2004 Apr 16. | ||||||||||
| Title: | The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter. | ||||||||||
| Author: | Coady, Michael J|Chang, Min-Hwang|Charron, Francois M|Plata, Consuelo|Wallendorff, Bernadette|Sah, Jerome Frank|Markowitz, Sanford D|Romero, Michael F|Lapointe, Jean-Yves | ||||||||||
| PMID: | 15090606 | ||||||||||
| 7. | |||||||||||
| Journal: | J Agric Food Chem. 2004 May 5;52(9):2512-7. | ||||||||||
| Title: | Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines. | ||||||||||
| Author: | Seeram, Navindra P|Adams, Lynn S|Hardy, Mary L|Heber, David | ||||||||||
| PMID: | 15113149 | ||||||||||
| 8. | |||||||||||
| Journal: | Tumour Biol. 2004 May-Jun;25(3):134-40. | ||||||||||
| Title: | Aberrant methylation and histone deacetylation associated with silencing of SLC5A8 in gastric cancer. | ||||||||||
| Author: | Ueno, Masako|Toyota, Minoru|Akino, Kimishige|Suzuki, Hiromu|Kusano, Masanobu|Satoh, Ayumi|Mita, Hiroaki|Sasaki, Yasushi|Nojima, Masanori|Yanagihara, Kazuyoshi|Hinoda, Yuji|Tokino, Takashi|Imai, Kohzoh | ||||||||||
| PMID: | 15361710 | ||||||||||
| 9. | |||||||||||
| Journal: | Mod Pathol. 2005 Feb;18(2):170-8. | ||||||||||
| Title: | Progressive methylation during the serrated neoplasia pathway of the colorectum. | ||||||||||
| Author: | Dong, Seung M|Lee, Eui J|Jeon, Eun S|Park, Cheol K|Kim, Kyoung-Mee | ||||||||||
| PMID: | 15389252 | ||||||||||
| 10. | |||||||||||
| Journal: | Biochem Soc Trans. 2005 Feb;33(Pt 1):237-40. | ||||||||||
| Title: | Biological functions of SLC5A8, a candidate tumour suppressor. | ||||||||||
| Author: | Ganapathy, V|Gopal, E|Miyauchi, S|Prasad, P D | ||||||||||
| PMID: | 15667316 | ||||||||||
| 11. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2006 May 9;103(19):7270-5. Epub 2006 May 2. | ||||||||||
| Title: | Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT. | ||||||||||
| Author: | Paroder, Viktoriya|Spencer, Shelly R|Paroder, Monika|Arango, Diego|Schwartz, Simo Jr|Mariadason, John M|Augenlicht, Leonard H|Eskandari, Sepehr|Carrasco, Nancy | ||||||||||
| PMID: | 16670197 | ||||||||||
| 12. | |||||||||||
| Journal: | Life Sci. 2006 Apr 18;78(21):2419-25. Epub 2005 Dec 20. | ||||||||||
| Title: | SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. | ||||||||||
| Author: | Gupta, Naren|Martin, Pamela M|Prasad, Puttur D|Ganapathy, Vadivel | ||||||||||
| PMID: | 16375929 | ||||||||||
| 13. | |||||||||||
| Journal: | AAPS J. 2008;10(1):193-9. | ||||||||||
| Title: | Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. | ||||||||||
| Author: | Ganapathy, Vadivel|Thangaraju, Muthusamy|Gopal, Elangovan|Martin, Pamela M|Itagaki, Shiro|Miyauchi, Seiji|Prasad, Puttur D | ||||||||||
| PMID: | 18446519 | ||||||||||
| 14. | |||||||||||
| Journal: | J Gastrointest Surg. 2008 Oct;12(10):1773-81; discussion 1781-2. | ||||||||||
| Title: | Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer. | ||||||||||
| Author: | Thangaraju, Muthusamy|Cresci, Gail|Itagaki, Shiro|Mellinger, John|Browning, Darren D|Berger, Franklin G|Prasad, Puttur D|Ganapathy, Vadivel | ||||||||||
| PMID: | 18661192 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncol Rep. 2008 Oct;20(4):793-801. | ||||||||||
| Title: | Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats. | ||||||||||
| Author: | Kanauchi, Osamu|Mitsuyama, Keiichi|Andoh, Akira|Iwanaga, Toshihiko | ||||||||||
| PMID: | 18813820 | ||||||||||
| 16. | |||||||||||
| Journal: | Biochem J. 2009 Jan 1;417(1):379-89. | ||||||||||
| Title: | Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. | ||||||||||
| Author: | Thangaraju, Muthusamy|Carswell, Kristina N|Prasad, Puttur D|Ganapathy, Vadivel | ||||||||||
| PMID: | 18789002 | ||||||||||
| 17. | |||||||||||
| Journal: | Virchows Arch. 2009 Jul;455(1):99-100. | ||||||||||
| Title: | Anti-MTOC-MT antibody is commonly detected by AIT test in colorectal cancer patients. | ||||||||||
| Author: | Sir, Jung-Uk|Kim, Think-You | ||||||||||
| PMID: | 19513746 | ||||||||||
| 18. | |||||||||||
| Journal: | BMC Res Notes. 2009 Aug 19;2:164. | ||||||||||
| Title: | Measuring the combinatorial expression of solute transporters and metalloproteinases transcripts in colorectal cancer. | ||||||||||
| Author: | Kerr, Caroline A|Dunne, Robert|Hines, Barney M|Zucker, Michelle|Cosgrove, Leah|Ruszkiewicz, Andrew|Lockett, Trevor|Head, Richard | ||||||||||
| PMID: | 19689820 | ||||||||||
| 19. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2010 Dec;42(12):1964-72. | ||||||||||
| Title: | Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells. | ||||||||||
| Author: | Zhang, Yu|Bao, Yong-Li|Yang, Mei-Ting|Wu, Yin|Yu, Chun-Lei|Huang, Yan-Xin|Sun, Ying|Zheng, Li-Hua|Li, Yu-Xin | ||||||||||
| PMID: | 20732443 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2010 Aug;201(1):32-8. | ||||||||||
| Title: | Deletion mapping of chromosome region 12q13-24 in colorectal cancer. | ||||||||||
| Author: | Aytekin, Turkan|Ozaslan, Mehmet|Cengiz, Beyhan | ||||||||||
| PMID: | 20633766 | ||||||||||
| 21. | |||||||||||
| Journal: | Gastroenterology. 2010 Feb;138(2):627-35. | ||||||||||
| Title: | CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium. | ||||||||||
| Author: | Kakizaki, Fumihiko|Aoki, Koji|Miyoshi, Hiroyuki|Carrasco, Nancy|Aoki, Masahiro|Taketo, Makoto M | ||||||||||
| PMID: | 19900445 | ||||||||||
| 22. | |||||||||||
| Journal: | Am J Gastroenterol. 2010 Jul;105(7):1610-9. | ||||||||||
| Title: | Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer. | ||||||||||
| Author: | Garrity-Park, Megan M|Loftus, Edward V Jr|Sandborn, William J|Bryant, Sandra C|Smyrk, Thomas C | ||||||||||
| PMID: | 20160714 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncogene. 2011 Sep 22;30(38):4026-37. | ||||||||||
| Title: | Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. | ||||||||||
| Author: | Babu, E|Ramachandran, S|CoothanKandaswamy, V|Elangovan, S|Prasad, P D|Ganapathy, V|Thangaraju, M | ||||||||||
| PMID: | 21499304 | ||||||||||
| 24. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2011 Apr;33(4):291-4. | ||||||||||
| Title: | [Safety and effectiveness of large dose compound Sophora flavescens Ait injection in the treatment of advanced malignant tumors]. | ||||||||||
| Author: | Li, Dao-rui|Lin, Hong-sheng | ||||||||||
| PMID: | 21575502 | ||||||||||
| 25. | |||||||||||
| Journal: | PLoS One. 2011;6(6):e20216. | ||||||||||
| Title: | SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas. | ||||||||||
| Author: | Brim, Hassan|Kumar, Krishan|Nazarian, Javad|Hathout, Yetrib|Jafarian, Amir|Lee, Edward|Green, William|Smoot, Duane|Park, Jong|Nouraie, Mehdi|Ashktorab, Hassan | ||||||||||
| PMID: | 21687703 | ||||||||||
| 26. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1405-15. | ||||||||||
| Title: | Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. | ||||||||||
| Author: | Zimmerman, Mary A|Singh, Nagendra|Martin, Pamela M|Thangaraju, Muthusamy|Ganapathy, Vadivel|Waller, Jennifer L|Shi, Huidong|Robertson, Keith D|Munn, David H|Liu, Kebin | ||||||||||
| PMID: | 22517765 | ||||||||||
| 27. | |||||||||||
| Journal: | J Cell Biochem. 2012 Sep;113(9):2937-47. | ||||||||||
| Title: | Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells. | ||||||||||
| Author: | Goncalves, Pedro|Catarino, Telmo|Gregorio, Ines|Martel, Fatima | ||||||||||
| PMID: | 22552910 | ||||||||||
| 28. | |||||||||||
| Journal: | Curr Drug Metab. 2013 Nov;14(9):994-1008. | ||||||||||
| Title: | Butyrate and colorectal cancer: the role of butyrate transport. | ||||||||||
| Author: | Goncalves, Pedro|Martel, Fatima | ||||||||||
| PMID: | 24160296 | ||||||||||
| 29. | |||||||||||
| Journal: | PLoS One. 2013 Oct 8;8(10):e76865. | ||||||||||
| Title: | Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice. | ||||||||||
| Author: | Pussila, Marjaana|Sarantaus, Laura|Dermadi Bebek, Denis|Valo, Satu|Reyhani, Nima|Ollila, Saara|Paivarinta, Essi|Peltomaki, Paivi|Mutanen, Marja|Nystrom, Minna | ||||||||||
| PMID: | 24204690 | ||||||||||
| 30. | |||||||||||
| Journal: | Biochem J. 2015 Jul 15;469(2):267-78. | ||||||||||
| Title: | Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. | ||||||||||
| Author: | Gurav, Ashish|Sivaprakasam, Sathish|Bhutia, Yangzom D|Boettger, Thomas|Singh, Nagendra|Ganapathy, Vadivel | ||||||||||
| PMID: | 25984582 | ||||||||||
| 31. | |||||||||||
| Journal: | Clin Epigenetics. 2015 Jul 22;7:71. | ||||||||||
| Title: | DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas. | ||||||||||
| Author: | Valo, Satu|Kaur, Sippy|Ristimaki, Ari|Renkonen-Sinisalo, Laura|Jarvinen, Heikki|Mecklin, Jukka-Pekka|Nystrom, Minna|Peltomaki, Paivi | ||||||||||
| PMID: | 26203307 | ||||||||||
| 32. | |||||||||||
| Journal: | Ann Thorac Surg. 2015 May;99(5):1755-9. | ||||||||||
| Title: | Prognostic Significance of Aberrant Methylation of Solute Carrier Gene Family 5A8 in Lung Adenocarcinoma. | ||||||||||
| Author: | Ikeda, Koei|Shiraishi, Kenji|Koga, Takafumi|Motooka, Yamato|Fujino, Kosuke|Shibata, Hidekatsu|Mori, Takeshi|Suzuki, Makoto | ||||||||||
| PMID: | 25827678 | ||||||||||
| 33. | |||||||||||
| Journal: | Neurochem Int. 2016 Oct;99:110-132. | ||||||||||
| Title: | The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis? | ||||||||||
| Author: | Stilling, Roman M|van de Wouw, Marcel|Clarke, Gerard|Stanton, Catherine|Dinan, Timothy G|Cryan, John F | ||||||||||
| PMID: | 27346602 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncol Rep. 2016 Sep;36(3):1333-8. | ||||||||||
| Title: | Oxymatrine inhibits epithelial-mesenchymal transition through regulation of NF-kappaB signaling in colorectal cancer cells. | ||||||||||
| Author: | Liang, Li|Huang, Jiean | ||||||||||
| PMID: | 27430890 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 21;7(43):70639-70653. | ||||||||||
| Title: | Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. | ||||||||||
| Author: | Ferro, Suellen|Azevedo-Silva, Joao|Casal, Margarida|Corte-Real, Manuela|Baltazar, Fatima|Preto, Ana | ||||||||||
| PMID: | 28874966 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Rep. 2017 Feb;37(2):747-753. | ||||||||||
| Title: | Oxymatrine inhibits the migration of human colorectal carcinoma RKO cells via inhibition of PAI-1 and the TGF-beta1/Smad signaling pathway. | ||||||||||
| Author: | Wang, Xiaoyu|Liu, Chun|Wang, Jiaqi|Fan, Yue|Wang, Zhenghua|Wang, Yuanyuan | ||||||||||
| PMID: | 27959430 | ||||||||||
| 37. | |||||||||||
| Journal: | FEMS Microbiol Lett. 2017 Mar 1;364(6). pii: 3045906. | ||||||||||
| Title: | Effect of butyrate and Lactobacillus GG on a butyrate receptor and transporter during Campylobacter jejuni exposure. | ||||||||||
| Author: | Cresci, Gail A M|Mayor, Paul C|Thompson, Stuart A | ||||||||||
| PMID: | 28333199 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncol Rep. 2017 Jun;37(6):3509-3519. | ||||||||||
| Title: | Effective cytotoxic activity of OSW-1 on colon cancer by inducing apoptosis in vitro and in vivo. | ||||||||||
| Author: | Zhang, Yanhong|Fang, Fengqi|Fan, Kai|Zhang, Yanli|Zhang, Jie|Guo, Huishu|Yu, Peiyao|Ma, Jianmei | ||||||||||
| PMID: | 28440433 | ||||||||||
| 39. | |||||||||||
| Journal: | Compr Physiol. 2017 Dec 12;8(1):299-314. | ||||||||||
| Title: | Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis. | ||||||||||
| Author: | Sivaprakasam, Sathish|Bhutia, Yangzom D|Yang, Shengping|Ganapathy, Vadivel | ||||||||||
| PMID: | 29357130 | ||||||||||
| 40. | |||||||||||
| Journal: | Curr Med Chem. 2018 May 29. pii: CMC-EPUB-90782. | ||||||||||
| Title: | The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. | ||||||||||
| Author: | Gomes, Sara Daniela|Oliveira, Claudia Suellen|Azevedo-Silva, Joao|Casanova, Marta|Barreto, Judite|Pereira, Helena|Chaves, Susana|Rodrigues, Ligia|Casal, Margarida|Corte-Real, Manuela|Baltazar, Fatima|Preto, Ana | ||||||||||
| PMID: | 29848266 | ||||||||||