Primary Site >> Colorectal Cancer
Gene >> SLC19A1
| 1. | |||||||||||
| Journal: | Ann Oncol. 1995 Nov;6(9):871-81. | ||||||||||
| Title: | Folate-based thymidylate synthase inhibitors as anticancer drugs. | ||||||||||
| Author: | Jackman, A L|Calvert, A H | ||||||||||
| PMID: | 8624289 | ||||||||||
| 2. | |||||||||||
| Journal: | Eur J Cancer. 1995 Jul-Aug;31A(7-8):1277-82. | ||||||||||
| Title: | ZD1694 (Tomudex): a new thymidylate synthase inhibitor with activity in colorectal cancer. | ||||||||||
| Author: | Jackman, A L|Farrugia, D C|Gibson, W|Kimbell, R|Harrap, K R|Stephens, T C|Azab, M|Boyle, F T | ||||||||||
| PMID: | 7577036 | ||||||||||
| 3. | |||||||||||
| Journal: | Clin Cancer Res. 1996 Feb;2(2):227-43. | ||||||||||
| Title: | Thymidylate synthase inhibitors. | ||||||||||
| Author: | Touroutoglou, N|Pazdur, R | ||||||||||
| PMID: | 9816165 | ||||||||||
| 4. | |||||||||||
| Journal: | Invest New Drugs. 1996;14(3):305-16. | ||||||||||
| Title: | Tomudex (ZD1694): from concept to care, a programme in rational drug discovery. | ||||||||||
| Author: | Jackman, A L|Boyle, F T|Harrap, K R | ||||||||||
| PMID: | 8958186 | ||||||||||
| 5. | |||||||||||
| Journal: | Anticancer Drugs. 1997 Jan;8(1):3-16. | ||||||||||
| Title: | Folate-based thymidylate synthase inhibitors in cancer chemotherapy. | ||||||||||
| Author: | Takemura, Y|Jackman, A L | ||||||||||
| PMID: | 9147608 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Cancer. 2000 Sep 15;87(6):771-8. | ||||||||||
| Title: | Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates. | ||||||||||
| Author: | Backus, H H|Pinedo, H M|Wouters, D|Padron, J M|Molders, N|van Der Wilt, C L|van Groeningen, C J|Jansen, G|Peters, G J | ||||||||||
| PMID: | 10956384 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cancer Ther. 2003 Jun;2(6):535-41. | ||||||||||
| Title: | mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma. | ||||||||||
| Author: | Sowers, Rebecca|Toguchida, Junya|Qin, Jing|Meyers, Paul A|Healey, John H|Huvos, Andrew|Banerjee, Debabrata|Bertino, Joseph R|Gorlick, Richard | ||||||||||
| PMID: | 12813132 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Pharmacol. 2003 Aug 1;66(3):431-8. | ||||||||||
| Title: | Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. | ||||||||||
| Author: | Sigmond, Jennifer|Backus, Harold H J|Wouters, Dorine|Temmink, Olaf H|Jansen, Gerrit|Peters, Godefridus J | ||||||||||
| PMID: | 12907242 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):6012-9. | ||||||||||
| Title: | Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. | ||||||||||
| Author: | Odin, Elisabeth|Wettergren, Yvonne|Nilsson, Staffan|Willen, Roger|Carlsson, Goran|Spears, C Paul|Larsson, Lars|Gustavsson, Bengt | ||||||||||
| PMID: | 14676127 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Detect Prev. 2005;29(4):348-55. | ||||||||||
| Title: | Low expression of reduced folate carrier-1 and folylpolyglutamate synthase correlates with lack of a deleted in colorectal carcinoma mRNA splice variant in normal-appearing mucosa of colorectal carcinoma patients. | ||||||||||
| Author: | Wettergren, Yvonne|Odin, Elisabeth|Nilsson, Staffan|Willen, Roger|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 16122883 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2999-3003. | ||||||||||
| Title: | Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes. | ||||||||||
| Author: | Lightfoot, Tracy J|Skibola, Christine F|Willett, Eleanor V|Skibola, Danica R|Allan, James M|Coppede, Fabio|Adamson, Peter J|Morgan, Gareth J|Roman, Eve|Smith, Martyn T | ||||||||||
| PMID: | 16365025 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2509-16. | ||||||||||
| Title: | Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. | ||||||||||
| Author: | Ulrich, Cornelia M|Curtin, Karen|Potter, John D|Bigler, Jeannette|Caan, Bette|Slattery, Martha L | ||||||||||
| PMID: | 16284371 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Res. 2005 Feb 1;65(3):887-97. | ||||||||||
| Title: | Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. | ||||||||||
| Author: | Ma, David W L|Finnell, Richard H|Davidson, Laurie A|Callaway, Evelyn S|Spiegelstein, Ofer|Piedrahita, Jorge A|Salbaum, J Michael|Kappen, Claudia|Weeks, Brad R|James, Jill|Bozinov, Daniel|Lupton, Joanne R|Chapkin, Robert S | ||||||||||
| PMID: | 15705887 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Cancer Ther. 2006 Feb;5(2):438-49. | ||||||||||
| Title: | The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line. | ||||||||||
| Author: | Chattopadhyay, Shrikanta|Zhao, Rongbao|Krupenko, Sergey A|Krupenko, Natalia|Goldman, I David | ||||||||||
| PMID: | 16505119 | ||||||||||
| 15. | |||||||||||
| Journal: | J Nutr Biochem. 2007 May;18(5):305-12. | ||||||||||
| Title: | Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. | ||||||||||
| Author: | Lawrance, Andrea K|Deng, Liyuan|Brody, Lawrence C|Finnell, Richard H|Shane, Barry|Rozen, Rima | ||||||||||
| PMID: | 16963246 | ||||||||||
| 16. | |||||||||||
| Journal: | Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21. | ||||||||||
| Title: | Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. | ||||||||||
| Author: | Curtin, Karen|Slattery, Martha L|Ulrich, Cornelia M|Bigler, Jeannette|Levin, Theodore R|Wolff, Roger K|Albertsen, Hans|Potter, John D|Samowitz, Wade S | ||||||||||
| PMID: | 17449906 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2007 Nov;6(10):720-7. | ||||||||||
| Title: | Colorectal carcinomas with microsatellite instability display increased thymidylate synthase gene expression levels. | ||||||||||
| Author: | Odin, Elisabeth|Wettergren, Yvonne|Nilsson, Staffan|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 18039426 | ||||||||||
| 18. | |||||||||||
| Journal: | Scand J Clin Lab Invest. 2008;68(5):393-401. | ||||||||||
| Title: | The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study. | ||||||||||
| Author: | Eklof, V|Van Guelpen, B|Hultdin, J|Johansson, I|Hallmans, G|Palmqvist, R | ||||||||||
| PMID: | 19172696 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Med. 2008 Jul-Aug;14(7-8):412-21. | ||||||||||
| Title: | p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer. | ||||||||||
| Author: | Wettergren, Yvonne|Odin, Elisabeth|Nilsson, Staffan|Carlsson, Goran|Gustavsson, Bengt | ||||||||||
| PMID: | 18418463 | ||||||||||
| 20. | |||||||||||
| Journal: | J Microbiol Methods. 2008 Feb;72(2):124-32. | ||||||||||
| Title: | Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces. | ||||||||||
| Author: | Nechvatal, Jordan M|Ram, Jeffrey L|Basson, Marc D|Namprachan, Phanramphoei|Niec, Stephanie R|Badsha, Kawsar Z|Matherly, Larry H|Majumdar, Adhip P N|Kato, Ikuko | ||||||||||
| PMID: | 18162191 | ||||||||||
| 21. | |||||||||||
| Journal: | Am J Clin Nutr. 2008 Oct;88(4):1149-58. | ||||||||||
| Title: | Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. | ||||||||||
| Author: | DeVos, Lauren|Chanson, Aurelie|Liu, Zhenhua|Ciappio, Eric D|Parnell, Laurence D|Mason, Joel B|Tucker, Katherine L|Crott, Jimmy W | ||||||||||
| PMID: | 18842806 | ||||||||||
| 22. | |||||||||||
| Journal: | J Nutr Biochem. 2009 Aug;20(8):649-55. | ||||||||||
| Title: | Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. | ||||||||||
| Author: | Chapkin, Robert S|Kamen, Barton A|Callaway, Evelyn S|Davidson, Laurie A|George, Nysia I|Wang, Naisyin|Lupton, Joanne R|Finnell, Richard H | ||||||||||
| PMID: | 18926688 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Causes Control. 2010 Apr;21(4):597-608. | ||||||||||
| Title: | Genes involved with folate uptake and distribution and their association with colorectal cancer risk. | ||||||||||
| Author: | Figueiredo, Jane C|Levine, A Joan|Lee, Won H|Conti, David V|Poynter, Jenny N|Campbell, Peter T|Duggan, David|Lewinger, Juan Pablo|Martinez, Maria Elena|Ulrich, Cornelia M|Newcomb, Polly|Potter, John|Limburg, Paul J|Hopper, John|Jenkins, Mark A|Le Marchand | ||||||||||
| PMID: | 20037791 | ||||||||||
| 24. | |||||||||||
| Journal: | DNA Cell Biol. 2011 Oct;30(10):771-6. | ||||||||||
| Title: | Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer. | ||||||||||
| Author: | Jokic, Mladen|Brcic-Kostic, Krunoslav|Stefulj, Jasminka|Catela Ivkovic, Tina|Bozo, Loncar|Gamulin, Marija|Kapitanovic, Sanja | ||||||||||
| PMID: | 21438757 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5. | ||||||||||
| Title: | Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. | ||||||||||
| Author: | Curtin, Karen|Ulrich, Cornelia M|Samowitz, Wade S|Wolff, Roger K|Duggan, David J|Makar, Karen W|Caan, Bette J|Slattery, Martha L | ||||||||||
| PMID: | 21537397 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Nutr Food Res. 2013 Apr;57(4):607-27. | ||||||||||
| Title: | Folate-genetics and colorectal neoplasia: what we know and need to know next. | ||||||||||
| Author: | Figueiredo, Jane C|Levine, A Joan|Crott, Jimmy W|Baurley, James|Haile, Robert W | ||||||||||
| PMID: | 23401104 | ||||||||||
| 27. | |||||||||||
| Journal: | Mol Clin Oncol. 2013 Jul;1(4):661-667. | ||||||||||
| Title: | Immunohistochemical analysis of organic anion transporter 2 and reduced folate carrier 1 in colorectal cancer: Significance as a predictor of response to oral uracil/ftorafur plus leucovorin chemotherapy. | ||||||||||
| Author: | Nishino, Satoshi|Itoh, Ayumi|Matsuoka, Hiroshi|Maeda, Kotaro|Kamoshida, Shingo | ||||||||||
| PMID: | 24649225 | ||||||||||
| 28. | |||||||||||
| Journal: | Epigenetics. 2014 Apr;9(4):621-33. | ||||||||||
| Title: | Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism. | ||||||||||
| Author: | Coppede, Fabio|Migheli, Francesca|Lopomo, Angela|Failli, Alessandra|Legitimo, Annalisa|Consolini, Rita|Fontanini, Gabriella|Sensi, Elisa|Servadio, Adele|Seccia, Massimo|Zocco, Giuseppe|Chiarugi, Massimo|Spisni, Roberto|Migliore, Lucia | ||||||||||
| PMID: | 24500500 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer. 2014 Nov 1;120(21):3329-3337. | ||||||||||
| Title: | Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304). | ||||||||||
| Author: | Ulrich, Cornelia M|Rankin, Cathryn|Toriola, Adetunji T|Makar, Karen W|Altug-Teber, Ozge|Benedetti, Jacqueline K|Holmes, Rebecca S|Smalley, Stephen R|Blanke, Charles D|Lenz, Heinz-Josef | ||||||||||
| PMID: | 25041994 | ||||||||||
| 30. | |||||||||||
| Journal: | Gene. 2014 Jan 10;533(2):558-64. | ||||||||||
| Title: | Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population. | ||||||||||
| Author: | Jang, Moon Ju|Kim, Jong Woo|Jeon, Young Joo|Chong, So Young|Hong, Sung Pyo|Hwang, Seong Gyu|Oh, Doyeun|Cho, Yun Kyung|Ji, Young Geon|Kim, Nam Keun | ||||||||||
| PMID: | 24100087 | ||||||||||
| 31. | |||||||||||
| Journal: | Tumour Biol. 2015 Jul;36(7):5581-90. | ||||||||||
| Title: | DNA methylation and expression of the folate transporter genes in colorectal cancer. | ||||||||||
| Author: | Farkas, Sanja A|Befekadu, Rahel|Hahn-Stromberg, Victoria|Nilsson, Torbjorn K | ||||||||||
| PMID: | 25697897 | ||||||||||
| 32. | |||||||||||
| Journal: | Mol Clin Oncol. 2015 May;3(3):639-648. | ||||||||||
| Title: | Association between folate metabolism-related polymorphisms and colorectal cancer risk. | ||||||||||
| Author: | Kim, Jong Woo|Jeon, Young Joo|Jang, Moon Ju|Kim, Jung O|Chong, So Young|Ko, Kwang Hyun|Hwang, Seong Gyu|Oh, Doyeun|Oh, Jisu|Kim, Nam Keun | ||||||||||
| PMID: | 26137281 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Med. 2015 Jul 17;21:597-604. | ||||||||||
| Title: | Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy. | ||||||||||
| Author: | Odin, Elisabeth|Sonden, Arvid|Gustavsson, Bengt|Carlsson, Goran|Wettergren, Yvonne | ||||||||||
| PMID: | 26193446 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncol Res. 2017 Aug 7;25(7):1129-1140. | ||||||||||
| Title: | Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo. | ||||||||||
| Author: | Di Paolo, Antonello|Orlandi, Paola|Di Desidero, Teresa|Danesi, Romano|Bocci, Guido | ||||||||||
| PMID: | 28109077 | ||||||||||
| 35. | |||||||||||
| Journal: | PLoS One. 2017 Oct 2;12(10):e0185792. | ||||||||||
| Title: | One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation. | ||||||||||
| Author: | Moruzzi, Sara|Guarini, Patrizia|Udali, Silvia|Ruzzenente, Andrea|Guglielmi, Alfredo|Conci, Simone|Pattini, Patrizia|Martinelli, Nicola|Olivieri, Oliviero|Tammen, Stephanie A|Choi, Sang-Woon|Friso, Simonetta | ||||||||||
| PMID: | 28968444 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Lett. 2018 Jun;15(6):8215-8222. | ||||||||||
| Title: | Hypermethylation of protocadherin gamma subfamily A12 and solute carrier family 19 A 1 promoters contributes to the occurrence and metastasis of colorectal cancer. | ||||||||||
| Author: | Zhang, Cheng|Li, Jinyun|Huang, Tao|Chen, Cheng|Hong, Qingxiao|Ji, Huihui|Ye, Meng|Duan, Shiwei | ||||||||||
| PMID: | 29805555 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2018 Sep 29. pii: 10.1007/s00280-018-3690-9. | ||||||||||
| Title: | Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal cancer. | ||||||||||
| Author: | Taflin, Helena|Odin, Elisabeth|Derwinger, Kristoffer|Carlsson, Goran|Gustavsson, Bengt|Wettergren, Yvonne | ||||||||||
| PMID: | 30269276 | ||||||||||