Primary Site >> Colorectal Cancer

Gene >> SLC15A1

Journal: Mol Cancer Ther. 2005 Apr;4(4):659-67.
Title: Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
Author: Landowski, Christopher P|Vig, Balvinder S|Song, Xueqin|Amidon, Gordon L
PMID: 15827340
Journal: Pflugers Arch. 2006 Apr;452(1):71-80. Epub 2005 Nov 19.
Title: Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
Author: Vavricka, Stephan R|Musch, Mark W|Fujiya, Mikihiro|Kles, Keri|Chang, Laura|Eloranta, Jyrki J|Kullak-Ublick, Gerd A|Drabik, Ken|Merlin, Didier|Chang, Eugene B
PMID: 16328452
Journal: J Pharmacol Exp Ther. 2010 Jan;332(1):220-8.
Title: Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine.
Author: Anderson, Catriona M H|Jevons, Mark|Thangaraju, Muthusamy|Edwards, Noel|Conlon, Nichola J|Woods, Steven|Ganapathy, Vadivel|Thwaites, David T
PMID: 19789362
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G136-43.
Title: The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase.
Author: Pieri, Myrtani|Christian, Helen C|Wilkins, Robert J|Boyd, C A R|Meredith, David
PMID: 20430871
Journal: Biochim Biophys Acta. 2014 Jun;1840(6):1747-54.
Title: Nrf2 regulates the expression of the peptide transporter PEPT1 in the human colon carcinoma cell line Caco-2.
Author: Geillinger, Kerstin E|Kipp, Anna P|Schink, Kristin|Roder, Pia V|Spanier, Britta|Daniel, Hannelore
PMID: 24380877
Journal: J Med Chem. 2015 Mar 12;58(5):2452-64.
Title: Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.
Author: Ai, Yong|Kang, Fenghua|Huang, Zhangjian|Xue, Xiaowen|Lai, Yisheng|Peng, Sixun|Tian, Jide|Zhang, Yihua
PMID: 25675144
Journal: Asian Pac J Cancer Prev. 2016;17(4):2271-5.
Title: 5-Aminolevulinic Acid Fluorescence in Detection of Peritoneal Metastases.
Author: Yonemura, Yutaka|Canbay, Emel|Ishibashi, Haruaki|Nishino, Eisei|Endou, Yoshio|Sako, Shouzou|Ogura, Shun-Ichirou
PMID: 27221929
Journal: Cell Mol Gastroenterol Hepatol. 2016 May;2(3):340-357.
Title: Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
Author: Viennois, Emilie|Ingersoll, Sarah A|Ayyadurai, Saravanan|Zhao, Yuan|Wang, Lixin|Zhang, Mingzhen|Han, Moon Kwon|Garg, Pallavi|Xiao, Bo|Merlin, Didier
PMID: 27458604