Primary Site >> Colorectal Cancer

Gene >> SLC15A1

  • 2005
  • 2006
  • 2010
  • 2014
  • 2015
  • 2016
Ref: Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
PMID: 15827340
Ref: Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
PMID: 16328452
Ref: Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine.
PMID: 19789362
Ref: The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase.
PMID: 20430871
Ref: Nrf2 regulates the expression of the peptide transporter PEPT1 in the human colon carcinoma cell line Caco-2.
PMID: 24380877
Ref: Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.
PMID: 25675144
Ref: 5-Aminolevulinic Acid Fluorescence in Detection of Peritoneal Metastases.
PMID: 27221929
Ref: Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
PMID: 27458604