Primary Site >> Stomach Cancer

Gene >> SKP2

Journal: Cancer Res. 2002 Jul 1;62(13):3819-25.
Title: Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis.
Author: Masuda, Taka-aki|Inoue, Hiroshi|Sonoda, Hideto|Mine, Shinji|Yoshikawa, Yasuji|Nakayama, Keiko|Nakayama, Kei-Ichi|Mori, Masaki
PMID: 12097295
Journal: Cancer Res. 2003 Aug 1;63(15):4739-46.
Title: Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells.
Author: Eguchi, Hidetoshi|Herschenhous, Nicole|Kuzushita, Noriyoshi|Moss, Steven F
PMID: 12907657
Journal: Clin Cancer Res. 2003 Nov 15;9(15):5693-8.
Title: Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma.
Author: Masuda, Taka-Aki|Inoue, Hiroshi|Nishida, Koujiro|Sonoda, Hideto|Yoshikawa, Yasuji|Kakeji, Yoshihiro|Utsunomiya, Tohru|Mori, Masaki
PMID: 14654553
Journal: Ai Zheng. 2004 Feb;23(2):215-8.
Title: [Correlation of Skp2 and P27kip1 protein expression and clinicopathological features of prostate cancer].
Author: Zheng, Xiang-Yi|Ding, Wei|Xie, Li-Ping|Chen, Zhao-Dian
PMID: 14960249
Journal: Int J Oncol. 2005 Feb;26(2):353-60.
Title: COX-2 correlates with F-box protein, Skp2 expression and prognosis in human gastric carcinoma.
Author: Honjo, Soichiro|Kase, Satoru|Osaki, Mitsuhiko|Ardyanto, Tonang Dwi|Kaibara, Nobuaki|Ito, Hisao
PMID: 15645119
Journal: World J Gastroenterol. 2005 Nov 14;11(42):6716-21.
Title: Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma.
Author: Ma, Xiu-Mei|Liu, Ying|Guo, Jian-Wen|Liu, Jiang-Hui|Zuo, Lian-Fu
PMID: 16425372
Journal: Mod Pathol. 2006 Jan;19(1):49-58.
Title: Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis.
Author: Kim, Sung S|Meitner, Patricia|Konkin, Tamako A|Cho, Young S|Resnick, Murray B|Moss, Steven F
PMID: 16118628
Journal: Ai Zheng. 2006 Jan;25(1):56-61.
Title: [Correlation of Skp2 expression in gastric carcinoma to expression of P27 and PTEN].
Author: Ma, Xiu-Mei|Liu, Jiang-Hui|Guo, Jian-Wen|Liu, Ying|Zuo, Lian-Fu
PMID: 16405750
Journal: Clin Cancer Res. 2006 Feb 15;12(4):1215-20.
Title: Significance of skp2 expression in primary breast cancer.
Author: Sonoda, Hideto|Inoue, Hiroshi|Ogawa, Kazuhiko|Utsunomiya, Tohru|Masuda, Taka-aki|Mori, Masaki
PMID: 16489076
Journal: Int J Mol Med. 2006 Jul;18(1):201-8.
Title: Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus verniciflua Stokes in AGS gastric cancer cells.
Author: Kim, Ji Hye|Kim, Hwang-Phill|Jung, Chang-Hwa|Hong, Myung Hee|Hong, Mu-Chang|Bae, Hyun-Su|Lee, Sun-Dong|Park, Seon-Yeong|Park, Jong-Hyeong|Ko, Seong-Gyu
PMID: 16786174
Journal: Carcinogenesis. 2007 Aug;28(8):1622-8. Epub 2007 Mar 26.
Title: Mechanisms of growth arrest by zinc ribbon domain-containing 1 in gastric cancer cells.
Author: Hong, Liu|Zhao, Yunping|Han, Ying|Guo, Wei|Jin, Haifeng|Qiao, Taidong|Che, Zheng|Fan, Daiming
PMID: 17389617
Journal: Am J Surg Pathol. 2007 Jun;31(6):846-53.
Title: Microsatellite instability in endometrioid type endometrial adenocarcinoma is associated with poor prognostic indicators.
Author: An, Hee Jung|Kim, Kwang Il|Kim, Ji Young|Shim, Jeong Youn|Kang, Haeyoun|Kim, Tae Heon|Kim, Jin Kyung|Jeong, Jeongmi Kim|Lee, Sun Young|Kim, Seung Jo
PMID: 17527071
Journal: Cancer Lett. 2008 Jul 8;265(2):197-205.
Title: Inhibition of the PI3K-Akt/PKB survival pathway enhanced an ethanol extract of Rhus verniciflua Stokes-induced apoptosis via a mitochondrial pathway in AGS gastric cancer cell lines.
Author: Kim, Ji Hye|Go, Ho Yeon|Jin, Dong Hoon|Kim, Hwang-Phill|Hong, Myung Hee|Chung, Woo-Yeop|Park, Jong-Hyeong|Jang, Jun Bock|Jung, Hee|Shin, Yong Cheol|Kim, Sung-Hoon|Ko, Seong-Gyu
PMID: 18378393
Journal: J Pathol. 2009 Aug;218(4):419-27.
Title: FoxM1 is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent on p27 kip1.
Author: Zeng, Jiping|Wang, Lixiang|Li, Qiao|Li, Wenjuan|Bjorkholm, Magnus|Jia, Jihui|Xu, Dawei
PMID: 19235838
Journal: World J Gastroenterol. 2009 Aug 21;15(31):3874-83.
Title: Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma.
Author: Ma, Xiu-Mei|Yu, Hong|Huai, Na
PMID: 19701967
Journal: Anal Cell Pathol (Amst). 2012;35(4):285-95.
Title: Investigation and identification of let-7a related functional proteins in gastric carcinoma by proteomics.
Author: Zhu, Yimin|Xiao, Xingyuan|Dong, Lairong|Liu, Zhiming
PMID: 22596182
Journal: Tumour Biol. 2012 Oct;33(5):1281-90.
Title: Differentially expressed proteins identified in overexpressed let-7a gastric carcinoma cells by two-dimensional polyacrylamide gel electrophoresis.
Author: Zhu, Yimin|Xiao, Xingyuan|Dong, Lairong|Liu, Zhiming
PMID: 22968827
Journal: Tumour Biol. 2013 Feb;34(1):181-92.
Title: Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.
Author: Wei, Zheng|Jiang, Xian|Liu, Fengjun|Qiao, Haiquan|Zhou, Baoguo|Zhai, Bo|Zhang, Lianfeng|Zhang, Xuwen|Han, Likun|Jiang, Hongchi|Krissansen, Geoffrey W|Sun, Xueying
PMID: 23229098
Journal: Cell Signal. 2013 Apr;25(4):931-8.
Title: STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
Author: Wei, Zheng|Jiang, Xian|Qiao, Haiquan|Zhai, Bo|Zhang, Lianfeng|Zhang, Qiang|Wu, Yuanhong|Jiang, Hongchi|Sun, Xueying
PMID: 23333463
Journal: J Cell Biochem. 2014 Jan;115(1):34-41.
Title: Reversal of multidrug resistance in gastric cancer cells by E2F-1 downregulation in vitro and in vivo.
Author: Yan, Lin-Hai|Wang, Xiao-Tong|Yang, Jie|Kong, Fan-Biao|Lian, Chao|Wei, Wei-Yuan|Luo, Wen|Xie, Yu-Bo|Xiao, Qiang
PMID: 24038122
Journal: Zhonghua Zhong Liu Za Zhi. 2014 Mar;36(3):171-6.
Title: [Reversion of multidrug resistance of human gastric cancer SGC7901/DDP cells by E2F-1 gene silencing].
Author: Lian, Chao|Yang, Jie|Wang, Xiaotong|Xie, Yubo|Xiao, Qiang
PMID: 24785275
Journal: Cell Death Differ. 2014 Nov;21(11):1769-79.
Title: Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress.
Author: Kim, S-J|Lee, H-W|Gu Kang, H|La, S-H|Choi, Il Ju|Ro, J Y|Bresalier, R S|Song, J|Chun, K-H
PMID: 24971481
Journal: Oncotarget. 2014 Nov 30;5(22):11695-708.
Title: Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer.
Author: Yoon, Jung Hwan|Seo, Ho Seok|Choi, Won Seok|Kim, Olga|Nam, Suk Woo|Lee, Jung Young|Park, Won Sang
PMID: 25344918
Journal: World J Gastroenterol. 2015 Jan 14;21(2):491-501.
Title: E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo.
Author: Wei, Wei-Yuan|Yan, Lin-Hai|Wang, Xiao-Tong|Li, Lei|Cao, Wen-Long|Zhang, Xiao-Shi|Zhan, Ze-Xu|Yu, Han|Xie, Yu-Bo|Xiao, Qiang
PMID: 25593464
Journal: Mol Med Rep. 2015 Jul;12(1):905-12.
Title: Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC-803 human gastric cancer cell line in vivo.
Author: Wei, Weiyuan|Li, Lei|Wang, Xiaotong|Yan, Linhai|Cao, Wenlong|Zhan, Zexu|Zhang, Xiaoshi|Yu, Han|Xie, Yubo|Xiao, Qiang
PMID: 25738600
Journal: World J Gastroenterol. 2016 Apr 21;22(15):3992-4001.
Title: CacyBP/SIP nuclear translocation regulates p27Kip1 stability in gastric cancer cells.
Author: Niu, Ying-Lin|Li, Ya-Jun|Wang, Jing-Bo|Lu, Yuan-Yuan|Liu, Zhen-Xiong|Feng, Shan-Shan|Hu, Jian-Guo|Zhai, Hui-Hong
PMID: 27099442
Journal: Mol Med Rep. 2016 Oct;14(4):3917-24.
Title: Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1.
Author: Wen, Yanguang|Wang, Kuansong|Yang, Kaiyan
PMID: 27572672
Journal: Mol Cancer. 2017 Apr 26;16(1):83.
Title: Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer.
Author: Geng, Qirong|Liu, Jianjun|Gong, Zhaohui|Chen, Shangxiang|Chen, Shuai|Li, Xiaoxing|Lu, Yue|Zhu, Xiaofeng|Lin, Hui-Kuan|Xu, Dazhi
PMID: 28446188
Journal: Int J Oncol. 2017 Jun;50(6):2091-2100.
Title: Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.
Author: Zhuang, Kun|Zhang, Lingxia|Zhang, Xin|Tang, Hailing|Zhang, Jun|Yan, Yuan|Han, Kun|Guo, Hanqing
PMID: 28498440
Journal: Mol Med Rep. 2017 Aug;16(2):2163-2171.
Title: MicroRNA-508-5p suppresses metastasis in human gastric cancer by targeting S-phase kinaseassociated protein 2.
Author: Duan, Xiangguo|Bai, Jing|Wei, Jun|Li, Zhenhao|Liu, Xinlan|Xu, Guangxian
PMID: 28627698
Journal: Biochem Biophys Res Commun. 2018 Jan 15;495(3):2158-2164.
Title: FBXO2, a novel marker for metastasis in human gastric cancer.
Author: Sun, Xu|Wang, Teng|Guan, Zhang-Rui|Zhang, Chun|Chen, Yun|Jin, Jian|Hua, Dong
PMID: 29269301