Primary Site >> Stomach Cancer

Gene >> SKP2

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Ref: Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis.
PMID: 12097295
Ref: Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells.
PMID: 12907657
Ref: Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma.
PMID: 14654553
Ref: [Correlation of Skp2 and P27kip1 protein expression and clinicopathological features of prostate cancer].
PMID: 14960249
Ref: COX-2 correlates with F-box protein, Skp2 expression and prognosis in human gastric carcinoma.
PMID: 15645119
Ref: Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma.
PMID: 16425372
Ref: Altered expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis.
PMID: 16118628
Ref: [Correlation of Skp2 expression in gastric carcinoma to expression of P27 and PTEN].
PMID: 16405750
Ref: Significance of skp2 expression in primary breast cancer.
PMID: 16489076
Ref: Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus verniciflua Stokes in AGS gastric cancer cells.
PMID: 16786174
Ref: Mechanisms of growth arrest by zinc ribbon domain-containing 1 in gastric cancer cells.
PMID: 17389617
Ref: Microsatellite instability in endometrioid type endometrial adenocarcinoma is associated with poor prognostic indicators.
PMID: 17527071
Ref: Inhibition of the PI3K-Akt/PKB survival pathway enhanced an ethanol extract of Rhus verniciflua Stokes-induced apoptosis via a mitochondrial pathway in AGS gastric cancer cell lines.
PMID: 18378393
Ref: FoxM1 is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent on p27 kip1.
PMID: 19235838
Ref: Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma.
PMID: 19701967
Ref: Investigation and identification of let-7a related functional proteins in gastric carcinoma by proteomics.
PMID: 22596182
Ref: Differentially expressed proteins identified in overexpressed let-7a gastric carcinoma cells by two-dimensional polyacrylamide gel electrophoresis.
PMID: 22968827
Ref: Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.
PMID: 23229098
Ref: STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
PMID: 23333463
Ref: Reversal of multidrug resistance in gastric cancer cells by E2F-1 downregulation in vitro and in vivo.
PMID: 24038122
Ref: [Reversion of multidrug resistance of human gastric cancer SGC7901/DDP cells by E2F-1 gene silencing].
PMID: 24785275
Ref: Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress.
PMID: 24971481
Ref: Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer.
PMID: 25344918
Ref: E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo.
PMID: 25593464
Ref: Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC-803 human gastric cancer cell line in vivo.
PMID: 25738600
Ref: CacyBP/SIP nuclear translocation regulates p27Kip1 stability in gastric cancer cells.
PMID: 27099442
Ref: Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1.
PMID: 27572672
Ref: Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer.
PMID: 28446188
Ref: Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.
PMID: 28498440
Ref: MicroRNA-508-5p suppresses metastasis in human gastric cancer by targeting S-phase kinaseassociated protein 2.
PMID: 28627698
Ref: FBXO2, a novel marker for metastasis in human gastric cancer.
PMID: 29269301