Primary Site >> Colorectal Cancer
Gene >> SKP2
| 1. | |||||||||||
| Journal: | Cancer. 2001 May 1;91(9):1745-51. | ||||||||||
| Title: | Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. | ||||||||||
| Author: | Hershko, D|Bornstein, G|Ben-Izhak, O|Carrano, A|Pagano, M|Krausz, M M|Hershko, A | ||||||||||
| PMID: | 11335900 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer. 2004 Apr 15;100(8):1615-21. | ||||||||||
| Title: | Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma. | ||||||||||
| Author: | Shapira, Ma'anit|Ben-Izhak, Ofer|Bishara, Bishara|Futerman, Boris|Minkov, Ira|Krausz, Michael M|Pagano, Michele|Hershko, Dan D | ||||||||||
| PMID: | 15073847 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Oncol. 2004 Jul;25(1):87-95. | ||||||||||
| Title: | Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors. | ||||||||||
| Author: | Li, Jia-Qing|Wu, Fei|Masaki, Tsutomu|Kubo, Akihito|Fujita, Jiro|Dixon, Dan A|Beauchamp, R Daniel|Ishida, Toshihiko|Kuriyama, Shigeki|Imaida, Katsumi | ||||||||||
| PMID: | 15201993 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer. 2005 Apr 1;103(7):1336-46. | ||||||||||
| Title: | The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma. | ||||||||||
| Author: | Shapira, Ma'anit|Ben-Izhak, Ofer|Linn, Shai|Futerman, Boris|Minkov, Ira|Hershko, Dan D | ||||||||||
| PMID: | 15717322 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer. 2006 Aug 15;107(4):668-75. | ||||||||||
| Title: | Prognostic role of p27Kip1 deregulation in colorectal cancer. | ||||||||||
| Author: | Hershko, Dan D|Shapira, Ma'anit | ||||||||||
| PMID: | 16826582 | ||||||||||
| 6. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14009-14. | ||||||||||
| Title: | Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer. | ||||||||||
| Author: | Timmerbeul, Inke|Garrett-Engele, Carrie M|Kossatz, Uta|Chen, Xueyan|Firpo, Eduardo|Grunwald, Viktor|Kamino, Kenji|Wilkens, Ludwig|Lehmann, Ulrich|Buer, Jan|Geffers, Robert|Kubicka, Stefan|Manns, Michael P|Porter, Peggy L|Roberts, James M|Malek, Nisar P | ||||||||||
| PMID: | 16966613 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cancer. 2007 Jan 3;6:2. | ||||||||||
| Title: | Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses. | ||||||||||
| Author: | Kleivi, Kristine|Lind, Guro E|Diep, Chieu B|Meling, Gunn I|Brandal, Lin T|Nesland, Jahn M|Myklebost, Ola|Rognum, Torleiv O|Giercksky, Karl-Erik|Skotheim, Rolf I|Lothe, Ragnhild A | ||||||||||
| PMID: | 17201907 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Apr;6(4):525-33. | ||||||||||
| Title: | High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers. | ||||||||||
| Author: | Nishida, Naoshi|Nagasaka, Takeshi|Kashiwagi, Kazuhiro|Boland, C Richard|Goel, Ajay | ||||||||||
| PMID: | 17457043 | ||||||||||
| 9. | |||||||||||
| Journal: | Cell Death Differ. 2008 May;15(5):908-19. | ||||||||||
| Title: | p27 Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells. | ||||||||||
| Author: | Wang, Q|Zhou, Y|Wang, X|Evers, B M | ||||||||||
| PMID: | 18408738 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2008 May 1;68(9):3379-88. | ||||||||||
| Title: | Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer. | ||||||||||
| Author: | Uddin, Shahab|Ahmed, Maqbool|Bavi, Prashant|El-Sayed, Raafat|Al-Sanea, Nasser|AbdulJabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Al-Kuraya, Khawla S | ||||||||||
| PMID: | 18451165 | ||||||||||
| 11. | |||||||||||
| Journal: | Am J Pathol. 2008 Jul;173(1):217-28. | ||||||||||
| Title: | Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. | ||||||||||
| Author: | Fujita, Takeo|Liu, Weijun|Doihara, Hiroyoshi|Wan, Yong | ||||||||||
| PMID: | 18535175 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2009 Aug 1;69(15):6100-6. | ||||||||||
| Title: | Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells. | ||||||||||
| Author: | Hartman, Johan|Edvardsson, Karin|Lindberg, Karolina|Zhao, Chunyan|Williams, Cecilia|Strom, Anders|Gustafsson, Jan-Ake | ||||||||||
| PMID: | 19602591 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biol Chem. 2010 Mar 12;285(11):7995-8002. | ||||||||||
| Title: | Foxp3 expression in p53-dependent DNA damage responses. | ||||||||||
| Author: | Jung, Da-Jung|Jin, Dong-Hoon|Hong, Seung-Woo|Kim, Jee-Eun|Shin, Jae-Sik|Kim, Daejin|Cho, Byung-Joo|Hwang, Young-Il|Kang, Jae-Seung|Lee, Wang-Jae | ||||||||||
| PMID: | 20075077 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Cancer Res. 2010 May;8(5):798-805. | ||||||||||
| Title: | STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells. | ||||||||||
| Author: | Wang, Shuo|Raven, Jennifer F|Koromilas, Antonis E | ||||||||||
| PMID: | 20407011 | ||||||||||
| 15. | |||||||||||
| Journal: | Med Hypotheses. 2011 May;76(5):697-9. | ||||||||||
| Title: | Modulation of liver X receptor signaling as a prevention and therapy for colon cancer. | ||||||||||
| Author: | Chuu, Chih-Pin | ||||||||||
| PMID: | 21333456 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2012 Sep 13;31(37):4128-38. | ||||||||||
| Title: | Involvement of the SKP2-p27(KIP1) pathway in suppression of cancer cell proliferation by RECK. | ||||||||||
| Author: | Yoshida, Y|Ninomiya, K|Hamada, H|Noda, M | ||||||||||
| PMID: | 22158033 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Gene Ther. 2013 Dec;20(12):690-4. | ||||||||||
| Title: | S-phase kinase-associated protein 2 knockdown blocks colorectal cancer growth via regulation of both p27 and p16 expression. | ||||||||||
| Author: | Xu, S-Y|Wang, F|Wei, G|Wang, B|Yang, J-Y|Huang, Y-Z|Zhang, L|Zheng, F|Guo, L-Y|Wang, J-N|Tang, J-M | ||||||||||
| PMID: | 24336114 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Oncol. 2013 Dec;43(6):1967-75. | ||||||||||
| Title: | Notch1-dependent regulation of p27 determines cell fate in colorectal cancer. | ||||||||||
| Author: | Hristova, Nevyana R|Tagscherer, Katrin E|Fassl, Anne|Kopitz, Juergen|Roth, Wilfried | ||||||||||
| PMID: | 24141420 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Carcinog. 2013 Nov;52(11):835-44. | ||||||||||
| Title: | The oxysterol receptors LXRalpha and LXRbeta suppress proliferation in the colon. | ||||||||||
| Author: | Vedin, Lise-Lotte|Gustafsson, Jan-Ake|Steffensen, Knut R | ||||||||||
| PMID: | 22610535 | ||||||||||
| 20. | |||||||||||
| Journal: | Tumour Biol. 2013 Apr;34(2):1107-17. | ||||||||||
| Title: | SKP2 overexpression is associated with a poor prognosis of rectal cancer treated with chemoradiotherapy and represents a therapeutic target with high potential. | ||||||||||
| Author: | Tian, Yu-Feng|Chen, Tzu-Ju|Lin, Ching-Yih|Chen, Li-Tzong|Lin, Li-Ching|Hsing, Chung-Hsi|Lee, Sung-Wei|Sheu, Ming-Jen|Lee, Hao-Hsien|Shiue, Yow-Ling|Huang, Hsuan-Ying|Pan, Hsin-Yi|Li, Chien-Feng|Chen, Shang-Hung | ||||||||||
| PMID: | 23328995 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Med Rep. 2014 Aug;10(2):1129-35. | ||||||||||
| Title: | Interference of Skp2 effectively inhibits the development and metastasis of colon carcinoma. | ||||||||||
| Author: | Chen, Haijin|Mo, Xiaodong|Yu, Jinlong|Huang, Shuxin|Huang, Zonghai|Gao, Liping | ||||||||||
| PMID: | 24913024 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Cancer Ther. 2014 Oct;13(10):2303-14. | ||||||||||
| Title: | The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. | ||||||||||
| Author: | Arensman, Michael D|Telesca, Donatello|Lay, Anna R|Kershaw, Kathleen M|Wu, Nanping|Donahue, Timothy R|Dawson, David W | ||||||||||
| PMID: | 25082960 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Oncol. 2015 Jan;46(1):113-22. | ||||||||||
| Title: | Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma. | ||||||||||
| Author: | Lam, Sze-Kwan|Li, Yuan-Yuan|Zheng, Chun-Yan|Ho, James Chung-Man | ||||||||||
| PMID: | 25335113 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2015 Feb;75(2):411-20. | ||||||||||
| Title: | Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells. | ||||||||||
| Author: | Khattar, Vinayak|Fried, Joshua|Xu, Bo|Thottassery, Jaideep V | ||||||||||
| PMID: | 25544127 | ||||||||||
| 25. | |||||||||||
| Journal: | RNA Biol. 2015;12(3):276-89. | ||||||||||
| Title: | microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. | ||||||||||
| Author: | Pan, Yi|Liang, Hongwei|Chen, Weixu|Zhang, Hongjie|Wang, Nan|Wang, Feng|Zhang, Suyang|Liu, Yanqing|Zhao, Chihao|Yan, Xin|Zhang, Junfeng|Zhang, Chen-Yu|Gu, Hongwei|Zen, Ke|Chen, Xi | ||||||||||
| PMID: | 25826661 | ||||||||||
| 26. | |||||||||||
| Journal: | J Gastrointestin Liver Dis. 2015 Jun;24(2):225-34. | ||||||||||
| Title: | The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer. | ||||||||||
| Author: | Bochis, Ovidiu V|Irimie, Alexandru|Pichler, Martin|Berindan-Neagoe, Ioana | ||||||||||
| PMID: | 26114183 | ||||||||||
| 27. | |||||||||||
| Journal: | J Nat Prod. 2015 Dec 24;78(12):2983-93. | ||||||||||
| Title: | Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells. | ||||||||||
| Author: | Jung, Cholomi|Hong, Ji-Young|Bae, Song Yi|Kang, Sam Sik|Park, Hyen Joo|Lee, Sang Kook | ||||||||||
| PMID: | 26595875 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 13;7(37):58931-58938. | ||||||||||
| Title: | Downregulated long non-coding RNA CLMAT3 promotes the proliferation of colorectal cancer cells by targeting regulators of the cell cycle pathway. | ||||||||||
| Author: | Ye, Le-Chi|Chen, Tao|Zhu, De-Xiang|Lv, Shi-Xu|Qiu, Jun-Jun|Xu, Jianmin|Yuan, Feng-Lai|Wei, Ye | ||||||||||
| PMID: | 27391344 | ||||||||||
| 29. | |||||||||||
| Journal: | Sci Rep. 2016 Jul 15;6:29869. | ||||||||||
| Title: | Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer. | ||||||||||
| Author: | Bi, Haoran|Tian, Tian|Zhu, Lin|Zhou, Haibo|Hu, Hanqing|Liu, Yanhong|Li, Xia|Hu, Fulan|Zhao, Yashuang|Wang, Guiyu | ||||||||||
| PMID: | 27417709 | ||||||||||
| 30. | |||||||||||
| Journal: | Sci Rep. 2017 Apr 4;7(1):641. | ||||||||||
| Title: | Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. | ||||||||||
| Author: | Ohshima, Keiichi|Hatakeyama, Keiichi|Nagashima, Takeshi|Watanabe, Yuko|Kanto, Kaori|Doi, Yuki|Ide, Tomomi|Shimoda, Yuji|Tanabe, Tomoe|Ohnami, Sumiko|Ohnami, Shumpei|Serizawa, Masakuni|Maruyama, Koji|Akiyama, Yasuto|Urakami, Kenichi|Kusuhara, Masatoshi|Moc | ||||||||||
| PMID: | 28377632 | ||||||||||
| 31. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. | ||||||||||
| Title: | The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K | ||||||||||
| PMID: | 28675510 | ||||||||||
| 32. | |||||||||||
| Journal: | J Ethnopharmacol. 2017 Sep 14;209:305-316. | ||||||||||
| Title: | Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway. | ||||||||||
| Author: | Lin, Yin-Yin|Lee, I-Yun|Huang, Wen-Shih|Lin, Yu-Shin|Kuan, Feng-Che|Shu, Li-Hsin|Cheng, Yu-Ching|Yang, Yao-Hsu|Wu, Ching-Yuan | ||||||||||
| PMID: | 28807849 | ||||||||||
| 33. | |||||||||||
| Journal: | J BUON. 2017 Sep-Oct;22(5):1122-1130. | ||||||||||
| Title: | The prognostic role of Skp2 and the tumor suppressor protein p27 in colorectal cancer. | ||||||||||
| Author: | Vasile Bochis, Ovidiu|Achimas-Cadariu, Patriciu|Vlad, Catalin|Fetica, Bogdan|Corneliu Leucuta, Daniel|Ioan Busuioc, Constantin|Irimie, Alexandru | ||||||||||
| PMID: | 29135092 | ||||||||||
| 34. | |||||||||||
| Journal: | J Ethnopharmacol. 2018 Mar 1;213:446. | ||||||||||
| Title: | Corrigendum to "Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway" [J. Ethnopharmacol. 209 (2017) 305-316]. | ||||||||||
| Author: | Lin, Yin-Yin|Lee, I-Yun|Huang, Wen-Shih|Lin, Yu-Shin|Kuan, Feng-Che|Shu, Li-Hsin|Cheng, Yu-Ching|Yang, Yao-Hsu|Wu, Ching-Yuan | ||||||||||
| PMID: | 29150229 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncogene. 2018 Mar;37(13):1759-1774. | ||||||||||
| Title: | NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. | ||||||||||
| Author: | Shen, Liangliang|Qu, Xuan|Li, Huichen|Xu, Chunsheng|Wei, Mengying|Wang, Qinhao|Ru, Yi|Liu, Bei|Xu, Yuqiao|Li, Kai|Hu, Junbi|Wang, Lifeng|Ma, Yongzheng|Li, Mengyang|Lai, Xiaofeng|Gao, Lei|Wu, Kaichun|Yao, Libo|Zheng, Jianyong|Zhang, Jian | ||||||||||
| PMID: | 29343851 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Med Rep. 2018 Aug;18(2):1692-1703. | ||||||||||
| Title: | Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkinmediated mitophagy by suppressing AMPK/Skp2 pathways. | ||||||||||
| Author: | He, Lili|Gu, Kebo | ||||||||||
| PMID: | 29845197 | ||||||||||
| 37. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2018 Aug 7;37(1):187. | ||||||||||
| Title: | PCBP1 depletion promotes tumorigenesis through attenuation of p27(Kip1) mRNA stability and translation. | ||||||||||
| Author: | Shi, Hongshun|Li, Hui|Yuan, Ronghua|Guan, Wen|Zhang, Xiaomei|Zhang, Shaoyang|Zhang, Wenliang|Tong, Fang|Li, Li|Song, Zhihong|Wang, Changwei|Yang, Shulan|Wang, Haihe | ||||||||||
| PMID: | 30086790 | ||||||||||