Primary Site >> Colorectal Cancer

Gene >> SIRT6

Journal: J Cell Biochem. 2007 Apr 15;100(6):1376-86.
Title: GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis.
Author: Ma, Wenbin|Stafford, Lewis J|Li, Dali|Luo, Jian|Li, Xiaoying|Ning, Guang|Liu, Mingyao
PMID: 17131381
Journal: J Biol Chem. 2013 Jun 7;288(23):16274-81.
Title: FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
Author: Qi, Wentao|Fitchev, Philip S|Cornwell, Mona L|Greenberg, Jordan|Cabe, Maleen|Weber, Christopher R|Roy, Hemant K|Crawford, Susan E|Savkovic, Suzana D
PMID: 23603907
Journal: Epigenetics. 2013 Jun;8(6):612-23.
Title: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
Author: Rajendran, Praveen|Kidane, Ariam I|Yu, Tian-Wei|Dashwood, Wan-Mohaiza|Bisson, William H|Lohr, Christiane V|Ho, Emily|Williams, David E|Dashwood, Roderick H
PMID: 23770684
Journal: Cell Rep. 2013 Dec 26;5(6):1639-49.
Title: USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation.
Author: Lin, Zhenghong|Yang, Heeyoung|Tan, Can|Li, Jinping|Liu, Zhaojian|Quan, Qiu|Kong, Sinyi|Ye, Junsheng|Gao, Beixue|Fang, Deyu
PMID: 24332849
Journal: Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6.
Title: Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.
Author: Penrose, Harrison|Heller, Sandra|Cable, Chloe|Makboul, Rania|Chadalawada, Gita|Chen, Ying|Crawford, Susan E|Savkovic, Suzana D
PMID: 26657850
Journal: Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834.
Title: SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Author: Rizzo, Angela|Iachettini, Sara|Salvati, Erica|Zizza, Pasquale|Maresca, Carmen|D'Angelo, Carmen|Benarroch-Popivker, Delphine|Capolupo, Angela|Del Gaudio, Federica|Cosconati, Sandro|Di Maro, Salvatore|Merlino, Francesco|Novellino, Ettore|Amoreo, Carla Azzur
PMID: 27923994
Journal: J Cell Biochem. 2018 May;119(5):3957-3967.
Title: Overexpression of Sirt6 is a novel biomarker of malignant human colon carcinoma.
Author: Geng, Chang-Hui|Zhang, Chun-Ling|Zhang, Jing-Yan|Gao, Ping|He, Miao|Li, Yan-Lin
PMID: 29227545
Journal: Int J Oncol. 2018 Mar 5.
Title: Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway.
Author: Li, Ning|Mao, Dong|Cao, Yansha|Li, Hua|Ren, Fu|Li, Keyan
PMID: 29512698
Journal: Oncol Lett. 2018 Apr;15(4):5368-5374.
Title: SIRT6 inhibits colorectal cancer stem cell proliferation by targeting CDC25A.
Author: Liu, Wenguang|Wu, Manwu|Du, Hechun|Shi, Xiaoliang|Zhang, Tao|Li, Jie
PMID: 29552180
Journal: Biomed Pharmacother. 2018 Oct;106:109-116.
Title: Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling.
Author: Tian, Junhong|Yuan, Leilei
PMID: 29957460
Journal: Oncol Lett. 2018 Nov;16(5):5829-5837.
Title: Downregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer.
Author: Qi, Jia|Cui, Chunhui|Deng, Quanwen|Wang, Lifeng|Chen, Rihong|Zhai, Duanyang|Xie, Lang|Yu, Jinlong
PMID: 30333863