Primary Site >> Colorectal Cancer

Gene >> SHMT1

Journal: Int J Cancer. 2004 Jul 1;110(4):617-20.
Title: Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study.
Author: Chen, Jia|Kyte, Charles|Valcin, Martin|Chan, Wendy|Wetmur, James G|Selhub, Jacob|Hunter, David J|Ma, Jing
PMID: 15122597
Journal: Magy Onkol. 2005;49(1):3-7. Epub 2005 May 18.
Title: [Activity of the National Oncology R&D Consortium in 2004].
Author: Timar, Jozsef
PMID: 15902326
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2999-3003.
Title: Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes.
Author: Lightfoot, Tracy J|Skibola, Christine F|Willett, Eleanor V|Skibola, Danica R|Allan, James M|Coppede, Fabio|Adamson, Peter J|Morgan, Gareth J|Roman, Eve|Smith, Martyn T
PMID: 16365025
Journal: Magy Onkol. 2006;50(4):349-59. Epub 2007 Jan 10.
Title: [Developments in cancer management by innovative genomics. 2006 report of the National Cancer Consortium].
Author: Timar, Jozsef|Kasler, Miklos|Katai, Jozsef|Soos, Miklos|Mathiasz, Dora|Romany, Anna|Patthy, Laszlo|Kovacs, Gabor|Jozsa, Adrienn|Szilak, Laszlo|Forrai, Tamas
PMID: 17216011
Journal: Am J Clin Nutr. 2008 Nov;88(5):1413-8.
Title: Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients.
Author: Guerreiro, Catarina Sousa|Carmona, Bruno|Goncalves, Susana|Carolino, Elisabete|Fidalgo, Paulo|Brito, Miguel|Leitao, Carlos Nobre|Cravo, Marilia
PMID: 18996879
Journal: J Nutrigenet Nutrigenomics. 2008;1(4):196-204.
Title: Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk.
Author: Steck, Susan E|Keku, Temitope|Butler, Lesley M|Galanko, Joseph|Massa, Beri|Millikan, Robert C|Sandler, Robert S
PMID: 19776626
Journal: BMC Cancer. 2010 Oct 4;10:525.
Title: SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.
Author: Komlosi, Viktor|Hitre, Erika|Pap, Eva|Adleff, Vilmos|Reti, Andrea|Szekely, Eva|Biro, Anna|Rudnai, Peter|Schoket, Bernadette|Muller, Judit|Toth, Bela|Otto, Szabolcs|Kasler, Miklos|Kralovanszky, Judit|Budai, Barna
PMID: 20920350
Journal: Cancer Res. 2011 Mar 15;71(6):2098-107.
Title: Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.
Author: Macfarlane, Amanda J|Perry, Cheryll A|McEntee, Michael F|Lin, David M|Stover, Patrick J
PMID: 21406397
Journal: Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5.
Title: Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.
Author: Curtin, Karen|Ulrich, Cornelia M|Samowitz, Wade S|Wolff, Roger K|Duggan, David J|Makar, Karen W|Caan, Bette J|Slattery, Martha L
PMID: 21537397
Journal: PLoS Genet. 2012;8(3):e1002573.
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Author: Nilsson, Lisa M|Forshell, Tacha Zi Plym|Rimpi, Sara|Kreutzer, Christiane|Pretsch, Walter|Bornkamm, Georg W|Nilsson, Jonas A
PMID: 22438825
Journal: Mol Nutr Food Res. 2013 Apr;57(4):721-34.
Title: Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.
Author: Liu, Amy Y|Scherer, Dominique|Poole, Elizabeth|Potter, John D|Curtin, Karen|Makar, Karen|Slattery, Martha L|Caan, Bette J|Ulrich, Cornelia M
PMID: 22961839
Journal: Mol Nutr Food Res. 2013 Apr;57(4):607-27.
Title: Folate-genetics and colorectal neoplasia: what we know and need to know next.
Author: Figueiredo, Jane C|Levine, A Joan|Crott, Jimmy W|Baurley, James|Haile, Robert W
PMID: 23401104
Journal: Int J Colorectal Dis. 2013 Jul;28(7):925-32.
Title: A meta-analysis of the C1420T polymorphism in cytosolic serine hydroxymethyltransferase (SHMT1) among Caucasian colorectal cancer populations.
Author: Pabalan, Noel|Jarjanazi, Hamdi|Ozcelik, Hilmi
PMID: 23322534
Journal: J Nutr. 2014 Apr;144(4):419-24.
Title: Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.
Author: MacFarlane, Amanda J|McEntee, Michael F|Stover, Patrick J
PMID: 24500934
Journal: Cancer. 2014 Nov 1;120(21):3329-3337.
Title: Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).
Author: Ulrich, Cornelia M|Rankin, Cathryn|Toriola, Adetunji T|Makar, Karen W|Altug-Teber, Ozge|Benedetti, Jacqueline K|Holmes, Rebecca S|Smalley, Stephen R|Blanke, Charles D|Lenz, Heinz-Josef
PMID: 25041994
Journal: Biomed Pharmacother. 2014 Jul;68(6):757-62.
Title: Association between cytosolic serine hydroxymethyltransferase (SHMT1) gene polymorphism and cancer risk: a meta-analysis.
Author: Wang, Qianqian|Lu, Kai|Du, Haina|Zhang, Qian|Chen, Tao|Shu, Yongqian|Hua, Yibing|Zhu, Lingjun
PMID: 25194438
Journal: Am J Clin Nutr. 2015 Jun;101(6):1295-304.
Title: Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population.
Author: Zinck, John Wr|de Groh, Margaret|MacFarlane, Amanda J
PMID: 25948668
Journal: BBA Clin. 2015 Jan 5;3:107-12.
Title: Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence.
Author: Lucock, Mark|Yates, Zoe|Martin, Charlotte|Choi, Jeong-Hwa|Beckett, Emma|Boyd, Lyndell|LeGras, Kathleen|Ng, Xiaowei|Skinner, Virginia|Wai, Ron|Kho, Jeremy|Roach, Paul|Veysey, Martin
PMID: 26673393
Journal: PLoS One. 2017 Oct 2;12(10):e0185792.
Title: One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.
Author: Moruzzi, Sara|Guarini, Patrizia|Udali, Silvia|Ruzzenente, Andrea|Guglielmi, Alfredo|Conci, Simone|Pattini, Patrizia|Martinelli, Nicola|Olivieri, Oliviero|Tammen, Stephanie A|Choi, Sang-Woon|Friso, Simonetta
PMID: 28968444
Journal: Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409.
Title: Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Author: Ducker, Gregory S|Ghergurovich, Jonathan M|Mainolfi, Nello|Suri, Vipin|Jeong, Stephanie K|Hsin-Jung Li, Sophia|Friedman, Adam|Manfredi, Mark G|Gitai, Zemer|Kim, Hahn|Rabinowitz, Joshua D
PMID: 29073064
Journal: Curr Dev Nutr. 2018 Mar 13;2(5):nzy013.
Title: Dietary Uridine Decreases Tumorigenesis in the Apc(Min/+) Model of Intestinal Cancer.
Author: Field, Martha S|Lan, Xu|Stover, Denise M|Stover, Patrick J
PMID: 29955725