Primary Site >> Colorectal Cancer

Gene >> SHC1

Journal: Oncogene. 2000 Apr 6;19(15):1901-14.
Title: Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells.
Author: Yang, H|Jiang, D|Li, W|Liang, J|Gentry, L E|Brattain, M G
PMID: 10773880
Journal: J Cancer Res Clin Oncol. 2003 May;129(5):272-8. Epub 2003 May 14.
Title: Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells.
Author: Ukegawa, J-I|Takeuchi, Y|Kusayanagi, S|Mitamura, K
PMID: 12748850
Journal: Biochem J. 2006 Mar 15;394(Pt 3):647-56.
Title: Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling.
Author: Kato, Kengo|Shiga, Kiyoto|Yamaguchi, Kazunori|Hata, Keiko|Kobayashi, Toshimitsu|Miyazaki, Kaoru|Saijo, Shigeru|Miyagi, Taeko
PMID: 16241905
Journal: Anticancer Res. 2006 Jan-Feb;26(1A):121-7.
Title: Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells.
Author: Ahn, Eun Hyun|Schroeder, Joseph J
PMID: 16475687
Journal: J Biol Chem. 2007 Jul 6;282(27):19399-409. Epub 2007 May 12.
Title: Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase.
Author: Maa, Ming-Chei|Lee, Jenq-Chang|Chen, Yen-Jen|Chen, Yun-Ju|Lee, Yuch-Ching|Wang, Shan-Tair|Huang, Ching-Chung|Chow, Nan-Haw|Leu, Tzeng-Horng
PMID: 17496330
Journal: Clin Cancer Res. 2007 Oct 1;13(19):5798-804.
Title: p66 Shc tumor levels show a strong prognostic correlation with disease outcome in stage IIA colon cancer.
Author: Grossman, Steven R|Lyle, Stephen|Resnick, Murray B|Sabo, Edmond|Lis, Rosina T|Rosinha, Elizabeth|Liu, Qin|Hsieh, Chung-Cheng|Bhat, Gajanan|Frackelton, A Raymond Jr|Hafer, Laurie J
PMID: 17908971
Journal: Carcinogenesis. 2008 Mar;29(3):647-55.
Title: Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells.
Author: Seiden-Long, Isolde|Navab, Roya|Shih, Warren|Li, Ming|Chow, Jane|Zhu, Chang Qi|Radulovich, Nikolina|Saucier, Caroline|Tsao, Ming-Sound
PMID: 18192688
Journal: Neurosignals. 2008;16(2-3):235-45.
Title: Tyrosine phosphorylation of netrin receptors in netrin-1 signaling.
Author: Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng
PMID: 18253061
Journal: BMC Cancer. 2009 Jan 12;9:12.
Title: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.
Author: Sachdev, Sanjay|Bu, Yahao|Gelman, Irwin H
PMID: 19138410
Journal: BMC Cancer. 2011 Oct 2;11:421.
Title: Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.
Author: Muller, Kristin M|Tveteraas, Ingun H|Aasrum, Monica|Odegard, John|Dawood, Mona|Dajani, Olav|Christoffersen, Thoralf|Sandnes, Dagny L
PMID: 21961726
Journal: Oncology. 2012;82(3):153-64.
Title: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author: Fernandez-Marcelo, Tamara|Moran, Alberto|de Juan, Carmen|Pascua, Irene|Head, Jacqueline|Gomez, Ana|Hernando, Florentino|Lopez-Asenjo, Jose A|Hernandez, Susana|Sanchez-Pernaute, Andres|Torres, Antonio J|Benito, Manuel|Iniesta, Pilar
PMID: 22433385
Journal: J Transl Med. 2012 Dec 24;10:254.
Title: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo.
Author: Fan, Chung-Wei|Chen, Chun-Yu|Chen, Kuei-Tien|Shen, Chia-Rui|Kuo, Yung-Bin|Chen, Ya-Shan|Chou, Yeh-Pin|Wei, Wei-Shan|Chan, Err-Cheng
PMID: 23259795
Journal: Mol Biol (Mosk). 2012 Jan-Feb;46(1):139-46.
Title: [P66shc action on resistance of colon carcinoma RKO cells to oxidative stress].
Author: Galimov, E R|Sidorenko, A S|Tereshkova, A V|Pletiushkina, O Iu|Cherniak, B V|Chumakov, P M
PMID: 22642111
Journal: PLoS One. 2014 Mar 11;9(3):e86521.
Title: Prooxidant properties of p66shc are mediated by mitochondria in human cells.
Author: Galimov, Evgeny R|Chernyak, Boris V|Sidorenko, Alena S|Tereshkova, Alesya V|Chumakov, Peter M
PMID: 24618848
Journal: PLoS One. 2014 Aug 4;9(8):e103551.
Title: Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
Author: Lee, Jeeyun|Jain, Anjali|Kim, Phillip|Lee, Tani|Kuller, Anne|Princen, Fred|In-GuDo|Kim, Suk Hyeong|Park, Joon Oh|Park, Young Suk|Singh, Sharat|Kim, Hee Cheol
PMID: 25090459
Journal: Am J Cancer Res. 2015 May 15;5(6):1972-87. eCollection 2015.
Title: YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells.
Author: Dubois, Fanny|Leroy, Cedric|Simon, Valerie|Benistant, Christine|Roche, Serge
PMID: 26269757
Journal: Int J Clin Exp Pathol. 2015 Aug 1;8(8):9097-104. eCollection 2015.
Title: The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway.
Author: Zhang, Ling|Zhu, Shengtao|Shi, Xuesen|Sha, Weihong
PMID: 26464652
Journal: Biochim Biophys Acta. 2016 Oct;1862(10):1926-37.
Title: Novel miR-5582-5p functions as a tumor suppressor by inducing apoptosis and cell cycle arrest in cancer cells through direct targeting of GAB1, SHC1, and CDK2.
Author: An, Hyun-Ju|Kwak, Seo-Young|Yoo, Je-Ok|Kim, Jae-Sung|Bae, In-Hwa|Park, Myung-Jin|Cho, Mee-Yon|Kim, Joon|Han, Young-Hoon
PMID: 27475256
Journal: Oncol Rep. 2018 Mar;39(3):1516-1522.
Title: Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Author: Kim, In-Hye|Nam, Taek-Jeong
PMID: 29328495
Journal: Int J Mol Med. 2018 Jul;42(1):368-380.
Title: Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Author: Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo
PMID: 29693170