Primary Site >> Colorectal Cancer

Gene >> SGK1

Journal: Physiol Rev. 2002 Jan;82(1):245-89.
Title: Electrolyte transport in the mammalian colon: mechanisms and implications for disease.
Author: Kunzelmann, Karl|Mall, Marcus
PMID: 11773614
Journal: Cancer Biol Ther. 2007 Apr;6(4):494-503.
Title: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis.
Author: Goulet, Anne-Christine|Watts, George|Lord, Jean L|Nelson, Mark A
PMID: 17374985
Journal: Biochem Pharmacol. 2008 Jun 1;75(11):2122-34.
Title: Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells.
Author: Cornez, Isabelle|Creppe, Catherine|Gillard, Magali|Hennuy, Benoit|Chapelle, Jean-Paul|Dejardin, Emmanuel|Merville, Marie-Paule|Close, Pierre|Chariot, Alain
PMID: 18430410
Journal: J Biol Chem. 2008 Jul 11;283(28):19201-10.
Title: Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1.
Author: Dehner, Manuel|Hadjihannas, Michel|Weiske, Jorg|Huber, Otmar|Behrens, Jurgen
PMID: 18487207
Journal: Cell Physiol Biochem. 2009;23(1-3):133-42.
Title: APC sensitive gastric acid secretion.
Author: Rotte, Anand|Bhandaru, Madhuri|Foller, Michael|Biswas, Raja|Mack, Andreas F|Friedrich, Bjorn|Rexhepaj, Rexhep|Nasir, Omaima|Ackermann, Teresa F|Boini, Krishna M|Kunzelmann, Karl|Behrens, Jurgen|Lang, Florian
PMID: 19255508
Journal: IUBMB Life. 2009 Jul;61(7):768-76.
Title: Relative resistance of SGK1 knockout mice against chemical carcinogenesis.
Author: Nasir, Omaima|Wang, Kan|Foller, Michael|Gu, Shuchen|Bhandaru, Madhuri|Ackermann, Teresa F|Boini, Krishna M|Mack, Andreas|Klingel, Karin|Amato, Rosario|Perrotti, Nicola|Kuhl, Dietmar|Behrens, Jurgen|Stournaras, Christos|Lang, Florian
PMID: 19548318
Journal: Cell Physiol Biochem. 2010;25(2-3):271-8.
Title: SGK1-dependent intestinal tumor growth in APC-deficient mice.
Author: Wang, Kan|Gu, Shuchen|Nasir, Omaima|Foller, Michael|Ackermann, Teresa F|Klingel, Karin|Kandolf, Reinhard|Kuhl, Dietmar|Stournaras, Christos|Lang, Florian
PMID: 20110688
Journal: Int J Biochem Cell Biol. 2010 Oct;42(10):1571-5.
Title: Colorectal carcinoma cells--regulation of survival and growth by SGK1.
Author: Lang, Florian|Perrotti, Nicola|Stournaras, Christos
PMID: 20541034
Journal: PLoS One. 2010 Nov 5;5(11):e13840.
Title: Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.
Author: Lessi, Francesca|Beggs, Andrew|de Palo, Mariagrazia|Anti, Marcello|Macarone Palmieri, Raffaele|Francesconi, Simona|Gomes, Vito|Bevilacqua, Generoso|Tomlinson, Ian|Segditsas, Stefania
PMID: 21079778
Journal: FEBS J. 2012 Apr;279(7):1231-42.
Title: Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor.
Author: Schmidt, Eva-Maria|Gu, Shuchen|Anagnostopoulou, Vasileia|Alevizopoulos, Konstantinos|Foller, Michael|Lang, Florian|Stournaras, Christos
PMID: 22309306
Journal: Cell Physiol Biochem. 2013;32(4):838-48.
Title: Inhibition of colonic tumor growth by the selective SGK inhibitor EMD638683.
Author: Towhid, Syeda T|Liu, Gui-Lai|Ackermann, Teresa F|Beier, Norbert|Scholz, Wolfgang|Fuchss, Thomas|Toulany, Mahmoud|Rodemann, Hans-Peter|Lang, Florian
PMID: 24081014
Journal: Oncotarget. 2013 Nov;4(11):1948-62.
Title: Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1.
Author: Francipane, Maria Giovanna|Lagasse, Eric
PMID: 24185040
Journal: Oncogene. 2013 Sep 19;32(38):4572-8.
Title: Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells.
Author: Amato, R|Scumaci, D|D'Antona, L|Iuliano, R|Menniti, M|Di Sanzo, M|Faniello, M C|Colao, E|Malatesta, P|Zingone, A|Agosti, V|Costanzo, F S|Mileo, A M|Paggi, M G|Lang, F|Cuda, G|Lavia, P|Perrotti, N
PMID: 23108393
Journal: Cell Physiol Biochem. 2015;35(5):2069-77.
Title: Genistein inhibits human colorectal cancer growth and suppresses miR-95, Akt and SGK1.
Author: Qin, Jian|Chen, Jia Xin|Zhu, Zhou|Teng, Jia An
PMID: 25871428
Journal: Cell Physiol Biochem. 2015;35(5):2006-18.
Title: SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.
Author: D'Antona, Lucia|Amato, Rosario|Talarico, Cristina|Ortuso, Francesco|Menniti, Miranda|Dattilo, Vincenzo|Iuliano, Rodolfo|Gigliotti, Francesco|Artese, Anna|Costa, Giosue|Schenone, Silvia|Musumeci, Francesca|Abbruzzese, Claudia|Botta, Lorenzo|Trapasso, Franc
PMID: 25871776
Journal: Oncotarget. 2015 Nov 10;6(35):37511-25.
Title: Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
Author: Talarico, Cristina|D'Antona, Lucia|Scumaci, Domenica|Barone, Agnese|Gigliotti, Francesco|Fiumara, Claudia Vincenza|Dattilo, Vincenzo|Gallo, Enzo|Visca, Paolo|Ortuso, Francesco|Abbruzzese, Claudia|Botta, Lorenzo|Schenone, Silvia|Cuda, Giovanni|Alcaro, Stef
PMID: 26462020
Journal: Cancer Res. 2016 Oct 1;76(19):5615-5627.
Title: RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells.
Author: Di Cecilia, Serena|Zhang, Fan|Sancho, Ana|Li, SiDe|Aguilo, Francesca|Sun, Yifei|Rengasamy, Madhumitha|Zhang, Weijia|Del Vecchio, Luigi|Salvatore, Francesco|Walsh, Martin J
PMID: 27520449
Journal: J Cancer. 2017 Jul 20;8(12):2256-2262.
Title: Development of a new analog of SGK1 inhibitor and its evaluation as a therapeutic molecule of colorectal cancer.
Author: Liang, Xuchun|Lan, Chunling|Zhou, Jinzhe|Fu, Wencheng|Long, Xuesha|An, Yu|Jiao, Guanming|Wang, Kejin|Li, Yongqin|Xu, Jiahong|Huang, Qi|Xu, Bin|Xiao, Junjie
PMID: 28819428
Journal: Oncol Rep. 2017 Oct;38(4):2043-2050.
Title: Identification of hub genes, key miRNAs and potential molecular mechanisms of colorectal cancer.
Author: Wu, Shasha|Wu, Feixiang|Jiang, Zheng
PMID: 28902367
Journal: Exp Mol Med. 2017 Nov 24;49(11):e399.
Title: Therapeutic inhibition of SGK1 suppresses colorectal cancer.
Author: Liang, Xuchun|Lan, Chunling|Jiao, Guanming|Fu, Wencheng|Long, Xuesha|An, Yu|Wang, Kejin|Zhou, Jinzhe|Chen, Ting|Li, Yongqin|Xu, Jiahong|Huang, Qi|Xu, Bin|Xiao, Junjie
PMID: 29170478
Journal: Biomed Pharmacother. 2018 Feb;98:286-296.
Title: Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1.
Author: Liu, Tianyou|Yu, Tao|Hu, Haiying|He, Keping
PMID: 29274585
Journal: Clin Cancer Res. 2018 Oct 15. pii: 1078-0432.CCR-18-1033.
Title: SERUM- AND GLUCOCORTICOID-INDUCED KINASE SGK1 DIRECTLY PROMOTES THE DIFFERENTIATION OF COLORECTAL CANCER CELLS AND RESTRAINS METASTASIS.
Author: Lee, Lennard Yw|Woolley, Connor E|Starkey, Thomas|Biswas, Sujata|Mirshahi, Tia S|Bardella, Chiara|Segditsas, Stefania|Irshad, Shazia|Tomlinson, Ian
PMID: 30322876