Primary Site >> Colorectal Cancer
Gene >> SGK1
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Electrolyte transport in the mammalian colon: mechanisms and implications for disease. PMID: 11773614 |
Ref: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis. PMID: 17374985 |
Ref: Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells. PMID: 18430410 Ref: Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1. PMID: 18487207 |
Ref: APC sensitive gastric acid secretion. PMID: 19255508 Ref: Relative resistance of SGK1 knockout mice against chemical carcinogenesis. PMID: 19548318 |
Ref: SGK1-dependent intestinal tumor growth in APC-deficient mice. PMID: 20110688 Ref: Colorectal carcinoma cells--regulation of survival and growth by SGK1. PMID: 20541034 Ref: Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation. PMID: 21079778 |
Ref: Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor. PMID: 22309306 |
Ref: Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells. PMID: 23108393 Ref: Inhibition of colonic tumor growth by the selective SGK inhibitor EMD638683. PMID: 24081014 Ref: Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1. PMID: 24185040 |
Ref: Genistein inhibits human colorectal cancer growth and suppresses miR-95, Akt and SGK1. PMID: 25871428 Ref: SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation. PMID: 25871776 Ref: Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy. PMID: 26462020 |
Ref: RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells. PMID: 27520449 |
Ref: Development of a new analog of SGK1 inhibitor and its evaluation as a therapeutic molecule of colorectal cancer. PMID: 28819428 Ref: Identification of hub genes, key miRNAs and potential molecular mechanisms of colorectal cancer. PMID: 28902367 Ref: Therapeutic inhibition of SGK1 suppresses colorectal cancer. PMID: 29170478 |
Ref: Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1. PMID: 29274585 Ref: SERUM- AND GLUCOCORTICOID-INDUCED KINASE SGK1 DIRECTLY PROMOTES THE DIFFERENTIATION OF COLORECTAL CANCER CELLS AND RESTRAINS METASTASIS. PMID: 30322876 |