Primary Site >> Liver Cancer

Gene >> SFRP1

Journal: J Hepatol. 2005 Jun;42(6):842-9.
Title: Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer.
Author: Calvisi, Diego F|Conner, Elizabeth A|Ladu, Sara|Lemmer, Eric R|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 15885355
Journal: Cancer. 2006 Aug 1;107(3):579-90.
Title: Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma.
Author: Shih, Yu-Lueng|Shyu, Rong-Yuan|Hsieh, Chung-Bao|Lai, Hung-Cheng|Liu, Kuo-Yu|Chu, Tang-Yuan|Lin, Ya-Wen
PMID: 16795071
Journal: J Biol Chem. 2006 Nov 24;281(47):35598-602.
Title: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1.
Author: He, Jing|Sheng, Tao|Stelter, Arwen A|Li, Chengxin|Zhang, Xiaoli|Sinha, Mala|Luxon, Bruce A|Xie, Jingwu
PMID: 17035233
Journal: Int J Cancer. 2007 Sep 1;121(5):1028-35.
Title: SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway.
Author: Shih, Yu-Lueng|Hsieh, Chung-Bao|Lai, Hung-Cheng|Yan, Ming-De|Hsieh, Tsai-Yuan|Chao, You-Chen|Lin, Ya-Wen
PMID: 17443492
Journal: BMC Cancer. 2007 Jul 12;7:126.
Title: Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma.
Author: Huang, Jian|Zhang, Yun-Li|Teng, Xiao-Mei|Lin, Yun|Zheng, Da-Li|Yang, Peng-Yuan|Han, Ze-Guang
PMID: 17626620
Journal: Br J Cancer. 2007 Nov 5;97(9):1260-5.
Title: Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma.
Author: Nomoto, S|Kinoshita, T|Kato, K|Otani, S|Kasuya, H|Takeda, S|Kanazumi, N|Sugimoto, H|Nakao, A
PMID: 17968429
Journal: Br J Cancer. 2008 Jul 8;99(1):143-50.
Title: Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma.
Author: Bengochea, A|de Souza, M M|Lefrancois, L|Le Roux, E|Galy, O|Chemin, I|Kim, M|Wands, J R|Trepo, C|Hainaut, P|Scoazec, J-Y|Vitvitski, L|Merle, P
PMID: 18577996
Journal: J Gastroenterol. 2008;43(5):378-89.
Title: Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
Author: Takagi, Hideyasu|Sasaki, Shigeru|Suzuki, Hiromu|Toyota, Minoru|Maruyama, Reo|Nojima, Masanori|Yamamoto, Hiroyuki|Omata, Masao|Tokino, Takashi|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 18592156
Journal: Cancer Res. 2009 Sep 1;69(17):6951-9.
Title: Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma.
Author: Hu, Jie|Dong, Aiwen|Fernandez-Ruiz, Veronica|Shan, Juanjuan|Kawa, Milosz|Martinez-Anso, Eduardo|Prieto, Jesus|Qian, Cheng
PMID: 19690140
Journal: Dig Dis Sci. 2010 Oct;55(10):2838-43.
Title: Reconstitution of secreted frizzled-related protein 1 suppresses tumor growth and lung metastasis in an orthotopic model of hepatocellular carcinoma.
Author: Jiang, Gui-Xing|Liu, Wei|Cui, Yun-Fu|Zhong, Xiang-Yu|Tai, Sheng|Wang, Zhi-Dong|Shi, Yu-Guang|Li, Chun-Long|Zhao, Shi-Yong
PMID: 20033841
Journal: Exp Mol Pathol. 2010 Apr;88(2):287-92.
Title: DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection.
Author: Feng, Qinghua|Stern, Joshua E|Hawes, Stephen E|Lu, Hiep|Jiang, Mingjun|Kiviat, Nancy B
PMID: 20079733
Journal: Anat Rec (Hoboken). 2010 Dec;293(12):2020-6.
Title: Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma.
Author: Qiu, Yunqing|Xu, Liqian|Zhou, Yang-Huai|Shi, Ming|Ma, Yingyu|Li, Meng|Li, Ji-Cheng
PMID: 21046672
Journal: Exp Mol Pathol. 2011 Aug;91(1):455-60.
Title: Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma.
Author: Hua, Dong|Hu, Yu|Wu, Yu-Yu|Cheng, Zhi-Hong|Yu, Jian|Du, Xiang|Huang, Zhao-Hui
PMID: 21600201
Journal: Exp Mol Pathol. 2011 Dec;91(3):702-7.
Title: Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma.
Author: Huang, Zhao-Hui|Hu, Yu|Hua, Dong|Wu, Yu-Yu|Song, Ming-Xu|Cheng, Zhi-Hong
PMID: 21884695
Journal: Tumour Biol. 2012 Apr;33(2):325-36.
Title: Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma.
Author: Kaur, Pushpinder|Mani, Samson|Cros, Marie-Pierre|Scoazec, Jean-Yves|Chemin, Isabelle|Hainaut, Pierre|Herceg, Zdenko
PMID: 22351518
Journal: Neoplasma. 2012;59(3):326-32.
Title: Epigenetic inactivation of the canonical Wnt antagonist secreted frizzled-related protein 1 in hepatocellular carcinoma cells.
Author: Wu, Y|Li, J|Sun, C Y|Zhou, Y|Zhao, Y F|Zhang, S J
PMID: 22296502
Journal: PLoS One. 2013 Dec 30;8(12):e84407.
Title: WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients.
Author: Liu, Yanhong|El-Serag, Hashem B|Jiao, Li|Lee, Juseog|Moore, David|Franco, Luis M|Tavakoli-Tabasi, Shahriar|Tsavachidis, Spiridon|Kuzniarek, Jill|Ramsey, David J|White, Donna L
PMID: 24386373
Journal: Oncogene. 2014 May 29;33(22):2826-35.
Title: Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial-mesenchymal transition.
Author: Quan, H|Zhou, F|Nie, D|Chen, Q|Cai, X|Shan, X|Zhou, Z|Chen, K|Huang, A|Li, S|Tang, N
PMID: 23770846
Journal: Int J Cancer. 2014 Aug 1;135(3):635-46.
Title: Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.
Author: Xie, Qing|Chen, Linlin|Shan, Xuefeng|Shan, Xiaoliang|Tang, Jia|Zhou, Fan|Chen, Qingmei|Quan, Huiqin|Nie, Dan|Zhang, Wenlu|Huang, Ai-Long|Tang, Ni
PMID: 24374650
Journal: World J Gastroenterol. 2015 May 28;21(20):6317-28.
Title: Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma.
Author: Ding, Shan-Long|Yang, Zi-Wei|Wang, Jie|Zhang, Xiao-Lei|Chen, Xiang-Mei|Lu, Feng-Min
PMID: 26034368
Journal: Mol Carcinog. 2016 Jul;55(7):1138-49.
Title: Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model.
Author: Sur, Subhayan|Pal, Debolina|Banerjee, Kaustav|Mandal, Suvra|Das, Ashes|Roy, Anup|Panda, Chinmay Kumar
PMID: 26154024
Journal: J Nutr Biochem. 2016 Jan;27:32-42.
Title: Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways.
Author: Sur, Subhayan|Pal, Debolina|Mandal, Syamsundar|Roy, Anup|Panda, Chinmay Kumar
PMID: 26386739
Journal: Anticancer Res. 2016 Feb;36(2):659-64.
Title: Loss of SFRP1 Expression Is Associated with Poor Prognosis in Hepatocellular Carcinoma.
Author: Davaadorj, Mandakhnaran|Imura, Satoru|Saito, Y U|Morine, Yuji|Ikemoto, Tetsuya|Yamada, Shinichiro|Takasu, Chie|Hiroki, Teraoku|Yoshikawa, Masato|Shimada, Mitsuo
PMID: 26851021
Journal: Int J Biochem Cell Biol. 2016 Dec;81(Pt A):195-207.
Title: Fibrous nests in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome.
Author: Desert, Romain|Mebarki, Sihem|Desille, Mireille|Sicard, Marie|Lavergne, Elise|Renaud, Stephanie|Bergeat, Damien|Sulpice, Laurent|Perret, Christine|Turlin, Bruno|Clement, Bruno|Musso, Orlando
PMID: 27545991
Journal: Oncotarget. 2016 Dec 6;7(49):81255-81267.
Title: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.
Author: Zhang, Cheng|Li, Jinyun|Huang, Tao|Duan, Shiwei|Dai, Dongjun|Jiang, Danjie|Sui, Xinbing|Li, Da|Chen, Yidan|Ding, Fei|Huang, Changxin|Chen, Gongying|Wang, Kaifeng
PMID: 27835605
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Nov;47(6):883-888.
Title: [The Evaluation Value of Methylation Status of CpG Island of SFRP1 and LINE1 Gene Promoter Area in the Prognosis of Hepatocellular Carcinoma.]
Author: Huang, Yuan|Wei, Ling|Sun, Ai-Min|Zhao, Rong-Ce|Zhang, Jing|Yang, Han-Teng|Li, Bo|Sun, Cheng-Jun|Ding, Xue-Qin|Gao, Bo|Zhong, Yan-Qin|Qin, Yang
PMID: 28598118
Journal: Clin Epigenetics. 2018 Mar 2;10:27.
Title: Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.
Author: Beck, Alexander|Trippel, Franziska|Wagner, Alexandra|Joppien, Saskia|Felle, Max|Vokuhl, Christian|Schwarzmayr, Thomas|Strom, Tim M|von Schweinitz, Dietrich|Langst, Gernot|Kappler, Roland
PMID: 29507645
Journal: J Clin Lab Anal. 2018 Mar 7.
Title: Application of multiplex methylated-specific PCR with capillary electrophoresis to explore prognostic value of TSGs hypermethylation for hepatocellular carcinoma.
Author: Huang, Yuan|Wei, Ling|Sun, Ai-Min|Li, Bo|Sun, Cheng-Jun|Liang, Wei-Bo|Liu, Qiu-Ying|Yu, Xiao-Qin|He, Jing-Yang|Qin, Yang
PMID: 29516551
Journal: Ann Hepatol. 2018 May-June;17(3):444-460.
Title: Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines.
Author: Uribe, Diego|Cardona, Andres|Esposti, Davide Degli|Cros, Marie-Pierre|Cuenin, Cyrille|Herceg, Zdenko|Camargo, Mauricio|Cortes-Mancera, Fabian M
PMID: 29735783
Journal: Onco Targets Ther. 2018 Jun 1;11:3281-3292.
Title: Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1.
Author: Chen, Yang|Zhang, Fan|Zhao, Yawei|He, Kan|Zheng, Xiao|Pan, Yue|Shao, Dan|Shang, Pei|Yang, Yongsheng|Zhang, Dan|Xie, Yingjun|Yao, Xiaoxiao|Chen, Li|Li, Jing|Zhang, Xuewen
PMID: 29910623