Primary Site >> Liver Cancer
Gene >> SFRP1
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Ref: Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer. PMID: 15885355 |
Ref: Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma. PMID: 16795071 Ref: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. PMID: 17035233 |
Ref: SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway. PMID: 17443492 Ref: Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. PMID: 17626620 Ref: Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma. PMID: 17968429 |
Ref: Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. PMID: 18577996 Ref: Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. PMID: 18592156 |
Ref: Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma. PMID: 19690140 |
Ref: Reconstitution of secreted frizzled-related protein 1 suppresses tumor growth and lung metastasis in an orthotopic model of hepatocellular carcinoma. PMID: 20033841 Ref: DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection. PMID: 20079733 Ref: Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma. PMID: 21046672 |
Ref: Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma. PMID: 21600201 Ref: Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma. PMID: 21884695 |
Ref: Epigenetic inactivation of the canonical Wnt antagonist secreted frizzled-related protein 1 in hepatocellular carcinoma cells. PMID: 22296502 Ref: Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma. PMID: 22351518 |
Ref: WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients. PMID: 24386373 |
Ref: Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial-mesenchymal transition. PMID: 23770846 Ref: Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway. PMID: 24374650 |
Ref: Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma. PMID: 26034368 |
Ref: Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model. PMID: 26154024 Ref: Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways. PMID: 26386739 Ref: Loss of SFRP1 Expression Is Associated with Poor Prognosis in Hepatocellular Carcinoma. PMID: 26851021 Ref: Fibrous nests in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome. PMID: 27545991 Ref: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma. PMID: 27835605 Ref: [The Evaluation Value of Methylation Status of CpG Island of SFRP1 and LINE1 Gene Promoter Area in the Prognosis of Hepatocellular Carcinoma.] PMID: 28598118 |
Ref: Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma. PMID: 29507645 Ref: Application of multiplex methylated-specific PCR with capillary electrophoresis to explore prognostic value of TSGs hypermethylation for hepatocellular carcinoma. PMID: 29516551 Ref: Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines. PMID: 29735783 Ref: Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1. PMID: 29910623 |