Primary Site >> Pancreatic Cancer
Gene >> SERPINE1
| 1. | |||||||||||
| Journal: | Cancer. 1992 Jun 15;69(12):2884-7. | ||||||||||
| Title: | Peaks in plasma plasminogen activator inhibitor-1 concentration may explain thrombotic events in cases of pancreatic carcinoma. | ||||||||||
| Author: | Andren-Sandberg, A|Lecander, I|Martinsson, G|Astedt, B | ||||||||||
| PMID: | 1591681 | ||||||||||
| 2. | |||||||||||
| Journal: | Am J Gastroenterol. 1993 Nov;88(11):1928-33. | ||||||||||
| Title: | Expression of plasminogen activators and their inhibitors in human pancreatic carcinoma: immunohistochemical study. | ||||||||||
| Author: | Takeuchi, Y|Nakao, A|Harada, A|Nonami, T|Fukatsu, T|Takagi, H | ||||||||||
| PMID: | 8237943 | ||||||||||
| 3. | |||||||||||
| Journal: | Surgery. 1998 Aug;124(2):388-93. | ||||||||||
| Title: | Transforming growth factor-beta 1 inhibits generation of angiostatin by human pancreatic cancer cells. | ||||||||||
| Author: | O'Mahony, C A|Albo, D|Tuszynski, G P|Berger, D H | ||||||||||
| PMID: | 9706163 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 1998 Oct 1;58(19):4461-7. | ||||||||||
| Title: | Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer. | ||||||||||
| Author: | Taniguchi, T|Kakkar, A K|Tuddenham, E G|Williamson, R C|Lemoine, N R | ||||||||||
| PMID: | 9766679 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 1999 Apr 2;274(14):9431-41. | ||||||||||
| Title: | Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation. | ||||||||||
| Author: | Stroschein, S L|Wang, W|Luo, K | ||||||||||
| PMID: | 10092624 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 1999 May 20;18(20):3152-8. | ||||||||||
| Title: | DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression. | ||||||||||
| Author: | Schwarte-Waldhoff, I|Klein, S|Blass-Kampmann, S|Hintelmann, A|Eilert, C|Dreschers, S|Kalthoff, H|Hahn, S A|Schmiegel, W | ||||||||||
| PMID: | 10340387 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Cancer. 1999 Oct 8;83(2):247-54. | ||||||||||
| Title: | TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor. | ||||||||||
| Author: | Kornmann, M|Tangvoranuntakul, P|Korc, M | ||||||||||
| PMID: | 10471535 | ||||||||||
| 8. | |||||||||||
| Journal: | J Gastrointest Surg. 1999 Jul-Aug;3(4):411-7. | ||||||||||
| Title: | Thrombospondin-1 and transforming growth factor beta-1 upregulate plasminogen activator inhibitor type 1 in pancreatic cancer. | ||||||||||
| Author: | Albo, D|Berger, D H|Vogel, J|Tuszynski, G P | ||||||||||
| PMID: | 10482694 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 1999 Sep 23;18(39):5363-72. | ||||||||||
| Title: | The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. | ||||||||||
| Author: | Kleeff, J|Ishiwata, T|Maruyama, H|Friess, H|Truong, P|Buchler, M W|Falb, D|Korc, M | ||||||||||
| PMID: | 10498890 | ||||||||||
| 10. | |||||||||||
| Journal: | Pancreas. 1999 Nov;19(4):370-6. | ||||||||||
| Title: | Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. | ||||||||||
| Author: | Wagner, M|Kleeff, J|Friess, H|Buchler, M W|Korc, M | ||||||||||
| PMID: | 10547197 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Cancer. 2000 Feb 15;85(4):555-62. | ||||||||||
| Title: | FGF-2 isoforms of 18 and 22.5 kDa differentially modulate t-PA and PAI-1 expressions on the pancreatic carcinoma cells AR4-2J: consequences on cell spreading and invasion. | ||||||||||
| Author: | Escaffit, F|Estival, A|Bertrand, C|Vaysse, N|Hollande, E|Clemente, F | ||||||||||
| PMID: | 10699930 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Exp Metastasis. 2000;18(4):343-52. | ||||||||||
| Title: | Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs. | ||||||||||
| Author: | Zhang, H|Morisaki, T|Matsunaga, H|Sato, N|Uchiyama, A|Hashizume, K|Nagumo, F|Tadano, J|Katano, M | ||||||||||
| PMID: | 11448066 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncogene. 2002 Aug 22;21(37):5783-90. | ||||||||||
| Title: | TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses. | ||||||||||
| Author: | Johnsen, Steven A|Subramaniam, Malayannan|Janknecht, Ralf|Spelsberg, Thomas C | ||||||||||
| PMID: | 12173049 | ||||||||||
| 14. | |||||||||||
| Journal: | Biochim Biophys Acta. 2002 Oct 9;1588(1):1-6. | ||||||||||
| Title: | Induction and expression of betaig-h3 in pancreatic cancer cells. | ||||||||||
| Author: | Schneider, Dominik|Kleeff, Jorg|Berberat, Pascal O|Zhu, Zhaowen|Korc, Murray|Friess, Helmut|Buchler, Markus W | ||||||||||
| PMID: | 12379307 | ||||||||||
| 15. | |||||||||||
| Journal: | Mol Cancer Ther. 2002 Jan;1(3):161-7. | ||||||||||
| Title: | Soluble type II transforming growth factor-beta receptor attenuates expression of metastasis-associated genes and suppresses pancreatic cancer cell metastasis. | ||||||||||
| Author: | Rowland-Goldsmith, Melissa A|Maruyama, Haruhisa|Matsuda, Kei|Idezawa, Takenao|Ralli, Monica|Ralli, Sonia|Korc, Murray | ||||||||||
| PMID: | 12467210 | ||||||||||
| 16. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2004 Aug 6;320(4):1148-55. | ||||||||||
| Title: | Glypican-1 antisense transfection modulates TGF-beta-dependent signaling in Colo-357 pancreatic cancer cells. | ||||||||||
| Author: | Li, Junsheng|Kleeff, Jorg|Kayed, Hany|Felix, Klaus|Penzel, Roland|Buchler, Markus W|Korc, Murray|Friess, Helmut | ||||||||||
| PMID: | 15249209 | ||||||||||
| 17. | |||||||||||
| Journal: | Gut. 2004 Nov;53(11):1688-97. | ||||||||||
| Title: | Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms. | ||||||||||
| Author: | Galli, A|Ceni, E|Crabb, D W|Mello, T|Salzano, R|Grappone, C|Milani, S|Surrenti, E|Surrenti, C|Casini, A | ||||||||||
| PMID: | 15479693 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Rep. 2005 Dec;14(6):1445-51. | ||||||||||
| Title: | Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis. | ||||||||||
| Author: | Inoue, Masafumi|Sawada, Tetsuji|Uchima, Yasutake|Kimura, Kenjiro|Nishihara, Tamahiro|Tanaka, Hiroaki|Yashiro, Masakazu|Yamada, Nobuya|Ohira, Masaichi|Hirakawa, Kosei | ||||||||||
| PMID: | 16273237 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Cancer Res. 2006 Mar;4(3):159-67. | ||||||||||
| Title: | Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system. | ||||||||||
| Author: | Sawai, Hirozumi|Liu, Joey|Reber, Howard A|Hines, Oscar J|Eibl, Guido | ||||||||||
| PMID: | 16547153 | ||||||||||
| 20. | |||||||||||
| Journal: | World J Surg. 2007 Mar;31(3):493-502; discussion 503. | ||||||||||
| Title: | High expression of plasminogen activator inhibitor-2 (PAI-2) is a predictor of improved survival in patients with pancreatic adenocarcinoma. | ||||||||||
| Author: | Smith, Ross|Xue, AiQun|Gill, Anthony|Scarlett, Christopher|Saxby, Alexander|Clarkson, Adele|Hugh, Thomas | ||||||||||
| PMID: | 17219285 | ||||||||||
| 21. | |||||||||||
| Journal: | Br J Cancer. 2007 Nov 19;97(10):1432-40. Epub 2007 Oct 16. | ||||||||||
| Title: | Gene expression profiling of liver metastases and tumour invasion in pancreatic cancer using an orthotopic SCID mouse model. | ||||||||||
| Author: | Niedergethmann, M|Alves, F|Neff, J K|Heidrich, B|Aramin, N|Li, L|Pilarsky, C|Grutzmann, R|Allgayer, H|Post, S|Gretz, N | ||||||||||
| PMID: | 17940512 | ||||||||||
| 22. | |||||||||||
| Journal: | BMC Cancer. 2007 Nov 12;7:209. | ||||||||||
| Title: | High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix composition. | ||||||||||
| Author: | Klein-Scory, Susanne|Zapatka, Marc|Eilert-Micus, Christina|Hoppe, Sabine|Schwarz, Elisabeth|Schmiegel, Wolff|Hahn, Stephan A|Schwarte-Waldhoff, Irmgard | ||||||||||
| PMID: | 17997817 | ||||||||||
| 23. | |||||||||||
| Journal: | Anticancer Res. 2007 Nov-Dec;27(6B):4149-57. | ||||||||||
| Title: | Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment. | ||||||||||
| Author: | Medicherla, Satyanarayana|Li, Lingyun|Ma, Jing Ying|Kapoun, Ann M|Gaspar, Nicholas J|Liu, Yu-Wang|Mangadu, Ruban|O'Young, Gilbert|Protter, Andrew A|Schreiner, George F|Wong, Darren H|Higgins, Linda S | ||||||||||
| PMID: | 18229422 | ||||||||||
| 24. | |||||||||||
| Journal: | Pancreas. 2008 Mar;36(2):173-7. | ||||||||||
| Title: | Significant down-regulation of the plasminogen activator inhibitor 1 mRNA in pancreatic cancer. | ||||||||||
| Author: | Warnecke-Eberz, Ute|Prenzel, Klaus L|Baldus, Stephan E|Metzger, Ralf|Dienes, Hans P|Bollschweiler, Elfriede|Hoelscher, Arnulf H|Schneider, Paul M | ||||||||||
| PMID: | 18376309 | ||||||||||
| 25. | |||||||||||
| Journal: | J Biol Chem. 2009 Jan 2;284(1):245-53. | ||||||||||
| Title: | Role of Ras signaling in the induction of snail by transforming growth factor-beta. | ||||||||||
| Author: | Horiguchi, Kana|Shirakihara, Takuya|Nakano, Ayako|Imamura, Takeshi|Miyazono, Kohei|Saitoh, Masao | ||||||||||
| PMID: | 19010789 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2011 Apr;43(4):604-12. | ||||||||||
| Title: | Early phase TGFbeta receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses. | ||||||||||
| Author: | Cutts, Anthony J|Soond, Surinder M|Powell, Steve|Chantry, Andrew | ||||||||||
| PMID: | 21187158 | ||||||||||
| 27. | |||||||||||
| Journal: | Carcinogenesis. 2012 Mar;33(3):555-62. | ||||||||||
| Title: | DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA. | ||||||||||
| Author: | He, Xiangyi|Zheng, Zhong|Li, Jianfang|Ben, Qiwen|Liu, Jun|Zhang, Jianian|Ji, Jun|Yu, Beiqin|Chen, Xuehua|Su, Liping|Zhou, Lin|Liu, Bingya|Yuan, Yaozong | ||||||||||
| PMID: | 22223849 | ||||||||||
| 28. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Dec 15;19(24):6957-66. | ||||||||||
| Title: | Prognostic and predictive blood-based biomarkers in patients with advanced pancreatic cancer: results from CALGB80303 (Alliance). | ||||||||||
| Author: | Nixon, Andrew B|Pang, Herbert|Starr, Mark D|Friedman, Paula N|Bertagnolli, Monica M|Kindler, Hedy L|Goldberg, Richard M|Venook, Alan P|Hurwitz, Herbert I | ||||||||||
| PMID: | 24097873 | ||||||||||
| 29. | |||||||||||
| Journal: | Dig Dis Sci. 2014 May;59(5):968-75. | ||||||||||
| Title: | Reverse-phase protein array analysis to identify biomarker proteins in human pancreatic cancer. | ||||||||||
| Author: | Huang, Yu-Jing|Frazier, Marsha L|Zhang, Nianxiang|Liu, Qian|Wei, Chongjuan | ||||||||||
| PMID: | 24248418 | ||||||||||
| 30. | |||||||||||
| Journal: | Eur J Surg Oncol. 2014 Oct;40(10):1331-7. | ||||||||||
| Title: | VEGF and Id-1 in pancreatic adenocarcinoma: prognostic significance and impact on angiogenesis. | ||||||||||
| Author: | Georgiadou, D|Sergentanis, T N|Sakellariou, S|Filippakis, G M|Zagouri, F|Vlachodimitropoulos, D|Psaltopoulou, T|Lazaris, A C|Patsouris, E|Zografos, G C | ||||||||||
| PMID: | 24480377 | ||||||||||
| 31. | |||||||||||
| Journal: | Hepatobiliary Surg Nutr. 2015 Oct;4(5):325-35. | ||||||||||
| Title: | Pancreatic cancer and thromboembolic disease, 150 years after Trousseau. | ||||||||||
| Author: | Ansari, David|Ansari, Daniel|Andersson, Roland|Andren-Sandberg, Ake | ||||||||||
| PMID: | 26605280 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Res. 2016 Jul 15;76(14):4149-59. | ||||||||||
| Title: | Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression. | ||||||||||
| Author: | Botla, Sandeep K|Savant, Soniya|Jandaghi, Pouria|Bauer, Andrea S|Mucke, Oliver|Moskalev, Evgeny A|Neoptolemos, John P|Costello, Eithne|Greenhalf, William|Scarpa, Aldo|Gaida, Matthias M|Buchler, Markus W|Strobel, Oliver|Hackert, Thilo|Giese, Nathalia A|Aug | ||||||||||
| PMID: | 27216198 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Med. 2018 May;7(5):2180-2191. | ||||||||||
| Title: | A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women. | ||||||||||
| Author: | White, Donna L|Hoogeveen, Ron C|Chen, Liang|Richardson, Peter|Ravishankar, Milan|Shah, Preksha|Tinker, Lesley|Rohan, Thomas|Whitsel, Eric A|El-Serag, Hashem B|Jiao, Li | ||||||||||
| PMID: | 29573228 | ||||||||||
| 34. | |||||||||||
| Journal: | Cancers (Basel). 2018 Oct 25;10(11). pii: cancers10110399. | ||||||||||
| Title: | Downregulation of TRAIL-Receptor 1 Increases TGFbeta Type II Receptor Expression and TGFbeta Signalling Via MicroRNA-370-3p in Pancreatic Cancer Cells. | ||||||||||
| Author: | Radke, David I|Ling, Qi|Hasler, Robert|Alp, Gokhan|Ungefroren, Hendrik|Trauzold, Anna | ||||||||||
| PMID: | 30366420 | ||||||||||