Primary Site >> Liver Cancer
Gene >> RUNX3
| 1. | |||||||||||
| Journal: | Lab Invest. 2004 Apr;84(4):479-84. | ||||||||||
| Title: | Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma. | ||||||||||
| Author: | Kim, Tai Young|Lee, Hyeon Joo|Hwang, Kyu Sang|Lee, Minjin|Kim, Jae Won|Bang, Yung-Jue|Kang, Gyeong Hoon | ||||||||||
| PMID: | 14968123 | ||||||||||
| 2. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2004 Apr;12(4):227-30. | ||||||||||
| Title: | [Analysis of methylation and loss of heterozygosity of RUNX3 gene in hepatocellular carcinoma and its clinical significance]. | ||||||||||
| Author: | Xiao, Wen-hua|Liu, Wei-wen | ||||||||||
| PMID: | 15099475 | ||||||||||
| 3. | |||||||||||
| Journal: | Ai Zheng. 2004 Nov;23(11):1354-6. | ||||||||||
| Title: | [Improvement and application of methylation-specific polymerase chain reaction]. | ||||||||||
| Author: | Xiao, Wen-Hua|Liu, Wei-Wen | ||||||||||
| PMID: | 15522190 | ||||||||||
| 4. | |||||||||||
| Journal: | World J Gastroenterol. 2004 Feb 1;10(3):376-80. | ||||||||||
| Title: | Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma. | ||||||||||
| Author: | Xiao, Wen-Hua|Liu, Wei-Wen | ||||||||||
| PMID: | 14760761 | ||||||||||
| 5. | |||||||||||
| Journal: | Liver Int. 2005 Apr;25(2):380-8. | ||||||||||
| Title: | Decreased expression and frequent allelic inactivation of the RUNX3 gene at 1p36 in human hepatocellular carcinoma. | ||||||||||
| Author: | Mori, Toshiaki|Nomoto, Shuji|Koshikawa, Katsumi|Fujii, Tsutomu|Sakai, Mitsuru|Nishikawa, Yoko|Inoue, Soichiro|Takeda, Shin|Kaneko, Tetsuya|Nakao, Akimasa | ||||||||||
| PMID: | 15780064 | ||||||||||
| 6. | |||||||||||
| Journal: | Exp Mol Med. 2005 Aug 31;37(4):276-81. | ||||||||||
| Title: | Hypermethylation of the RUNX3 gene in hepatocellular carcinoma. | ||||||||||
| Author: | Park, Won Sang|Cho, Yong Gu|Kim, Chang Jae|Song, Jae Hwi|Lee, Youn Soo|Kim, Su Young|Nam, Suk Woo|Lee, Sug Hyung|Yoo, Nam Jin|Lee, Jung Young | ||||||||||
| PMID: | 16155404 | ||||||||||
| 7. | |||||||||||
| Journal: | Anticancer Res. 2006 Sep-Oct;26(5B):3633-43. | ||||||||||
| Title: | Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis. | ||||||||||
| Author: | Miyagawa, Kouji|Sakakura, Chouhei|Nakashima, Susumu|Yoshikawa, Tetsuji|Kin, Shuichi|Nakase, Yuenn|Ito, Kosei|Yamagishi, Hisakazu|Ida, Hiroshi|Yazumi, Shujiro|Chiba, Tsutomu|Ito, Yoshiaki|Hagiwara, Akeo | ||||||||||
| PMID: | 17094378 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncol Rep. 2007 Nov;18(5):1225-30. | ||||||||||
| Title: | Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3. | ||||||||||
| Author: | Tan, Sing-Huang|Ida, Hiroshi|Lau, Quek-Choon|Goh, Boon-Cher|Chieng, Wei-Shieng|Loh, Marie|Ito, Yoshiaki | ||||||||||
| PMID: | 17914577 | ||||||||||
| 9. | |||||||||||
| Journal: | Br J Cancer. 2007 Nov 5;97(9):1260-5. | ||||||||||
| Title: | Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma. | ||||||||||
| Author: | Nomoto, S|Kinoshita, T|Kato, K|Otani, S|Kasuya, H|Takeda, S|Kanazumi, N|Sugimoto, H|Nakao, A | ||||||||||
| PMID: | 17968429 | ||||||||||
| 10. | |||||||||||
| Journal: | Hepatology. 2008 Mar;47(3):908-18. | ||||||||||
| Title: | Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. | ||||||||||
| Author: | Nishida, Naoshi|Nagasaka, Takeshi|Nishimura, Takafumi|Ikai, Iwao|Boland, C Richard|Goel, Ajay | ||||||||||
| PMID: | 18161048 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Biol Ther. 2008 May;7(5):669-76. Epub 2008 May 1. | ||||||||||
| Title: | RUNX3 inhibits growth of HCC cells and HCC xenografts in mice in combination with adriamycin. | ||||||||||
| Author: | Li, Xiaohua|Zhang, Ying|Zhang, Yafei|Qiao, Taidong|Wu, Kaichun|Ding, Jie|Liu, Jie|Fan, Daiming | ||||||||||
| PMID: | 18259121 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Cancer. 2009 Jul 15;125(2):388-97. | ||||||||||
| Title: | Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma. | ||||||||||
| Author: | Moribe, Toyoki|Iizuka, Norio|Miura, Toshiaki|Kimura, Naoki|Tamatsukuri, Shigeru|Ishitsuka, Hideo|Hamamoto, Yoshihiko|Sakamoto, Kazuhiko|Tamesa, Takao|Oka, Masaaki | ||||||||||
| PMID: | 19384946 | ||||||||||
| 13. | |||||||||||
| Journal: | Exp Cell Res. 2010 Jan 15;316(2):149-57. | ||||||||||
| Title: | RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells. | ||||||||||
| Author: | Gao, Juan|Chen, Yu|Wu, Kai-Chun|Liu, Jie|Zhao, Yan-Qiu|Pan, Yang-Lin|Du, Rui|Zheng, Guo-Rong|Xiong, Yi-Min|Xu, Hua-Lin|Fan, Dai-Ming | ||||||||||
| PMID: | 19800882 | ||||||||||
| 14. | |||||||||||
| Journal: | BMC Cancer. 2011 Jan 4;11:3. | ||||||||||
| Title: | Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis. | ||||||||||
| Author: | Nakanishi, Yutaka|Shiraha, Hidenori|Nishina, Shin-ichi|Tanaka, Shigetomi|Matsubara, Minoru|Horiguchi, Shigeru|Iwamuro, Masaya|Takaoka, Nobuyuki|Uemura, Masayuki|Kuwaki, Kenji|Hagihara, Hiroaki|Toshimori, Junichi|Ohnishi, Hideki|Takaki, Akinobu|Nakamura, S | ||||||||||
| PMID: | 21205319 | ||||||||||
| 15. | |||||||||||
| Journal: | J Cell Biochem. 2011 Mar;112(3):745-9. | ||||||||||
| Title: | Loss of runt-related transcription factor 3 causes development and progression of hepatocellular carcinoma. | ||||||||||
| Author: | Shiraha, Hidenori|Nishina, Shin-ichi|Yamamoto, Kazuhide | ||||||||||
| PMID: | 21328447 | ||||||||||
| 16. | |||||||||||
| Journal: | Hepatology. 2011 Mar;53(3):895-904. | ||||||||||
| Title: | Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice. | ||||||||||
| Author: | Aleksic, Kristina|Lackner, Carolin|Geigl, Jochen B|Schwarz, Martina|Auer, Martina|Ulz, Peter|Fischer, Maria|Trajanoski, Zlatko|Otte, Marcus|Speicher, Michael R | ||||||||||
| PMID: | 21374661 | ||||||||||
| 17. | |||||||||||
| Journal: | Exp Mol Pathol. 2011 Aug;91(1):455-60. | ||||||||||
| Title: | Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma. | ||||||||||
| Author: | Hua, Dong|Hu, Yu|Wu, Yu-Yu|Cheng, Zhi-Hong|Yu, Jian|Du, Xiang|Huang, Zhao-Hui | ||||||||||
| PMID: | 21600201 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncol Rep. 2011 Sep;26(3):523-31. | ||||||||||
| Title: | Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling. | ||||||||||
| Author: | Nishina, Shin-Ichi|Shiraha, Hidenori|Nakanishi, Yutaka|Tanaka, Shigetomi|Matsubara, Minoru|Takaoka, Nobuyuki|Uemura, Masayuki|Horiguchi, Shigeru|Kataoka, Junro|Iwamuro, Masaya|Yagi, Takahito|Yamamoto, Kazuhide | ||||||||||
| PMID: | 21637926 | ||||||||||
| 19. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2011;12(9):2285-90. | ||||||||||
| Title: | Loss of runt-related transcription factor 3 expression associated with human hepatocellular carcinoma progression and prognosis. | ||||||||||
| Author: | Li, Jianguo|Jiang, Xiaojie | ||||||||||
| PMID: | 22296371 | ||||||||||
| 20. | |||||||||||
| Journal: | Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Dec;25(6):441-4. | ||||||||||
| Title: | [The associated research on the expression of RUNX3 mRNA and protein in hepatic cell carcinoma as well as the relationship with clinical pathological parameters]. | ||||||||||
| Author: | Lu, Yan-Hui|Zheng, Rui-Dan|Xu, Cheng-Run|Chen, Jie|Wu, Wei-Ping|Chen, Bi-Fen|Li, Jian-Guo|Lin, Zhi-Chuan | ||||||||||
| PMID: | 22734230 | ||||||||||
| 21. | |||||||||||
| Journal: | J Cell Physiol. 2012 Mar;227(3):899-908. | ||||||||||
| Title: | Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth. | ||||||||||
| Author: | Park, Soo Young|Lee, Kyoung Bun|Lee, Min-Jae|Bae, Suk-Chul|Jang, Ja-June | ||||||||||
| PMID: | 21503886 | ||||||||||
| 22. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2012 Aug 24;425(2):468-72. | ||||||||||
| Title: | Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell. | ||||||||||
| Author: | Xu, Ning|Shen, Conghuan|Luo, Yi|Xia, Lei|Xue, Feng|Xia, Qiang|Zhang, Jianjun | ||||||||||
| PMID: | 22846564 | ||||||||||
| 23. | |||||||||||
| Journal: | Hepatology. 2012 Sep;56(3):994-1003. | ||||||||||
| Title: | Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma. | ||||||||||
| Author: | Nishida, Naoshi|Kudo, Masatoshi|Nagasaka, Takeshi|Ikai, Iwao|Goel, Ajay | ||||||||||
| PMID: | 22407776 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2012 Dec 1;131(11):2537-46. | ||||||||||
| Title: | Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma. | ||||||||||
| Author: | Tanaka, Shigetomi|Shiraha, Hidenori|Nakanishi, Yutaka|Nishina, Shin-Ichi|Matsubara, Minoru|Horiguchi, Shigeru|Takaoka, Nobuyuki|Iwamuro, Masaya|Kataoka, Junro|Kuwaki, Kenji|Hagihara, Hiroaki|Toshimori, Junichi|Ohnishi, Hideki|Takaki, Akinobu|Nakamura, Shi | ||||||||||
| PMID: | 22488108 | ||||||||||
| 25. | |||||||||||
| Journal: | Tumour Biol. 2014 Oct;35(10):10333-40. | ||||||||||
| Title: | Clinicopathological significance of RUNX3 gene hypermethylation in hepatocellular carcinoma. | ||||||||||
| Author: | Yang, Yuewu|Ye, Zhiqiang|Zou, Zengcheng|Xiao, Gemin|Luo, Gangjian|Yang, Hongzhi | ||||||||||
| PMID: | 25037468 | ||||||||||
| 26. | |||||||||||
| Journal: | Genet Mol Res. 2014 Jul 7;13(3):5182-9. | ||||||||||
| Title: | Relationship between RUNX3 methylation and hepatocellular carcinoma in Asian populations: a systematic review. | ||||||||||
| Author: | Lu, X X|Zhu, L Q|Pang, F|Sun, W|Ou, C|Li, Y|Cao, J|Hu, Y L | ||||||||||
| PMID: | 25061743 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer Invest. 2015 Apr;33(4):121-5. | ||||||||||
| Title: | RUNX3 Promoter Methylation Is Associated with Hepatocellular Carcinoma Risk: A Meta-Analysis. | ||||||||||
| Author: | Zhang, Xueyan|He, Hairong|Zhang, Xu|Guo, Wenjie|Wang, Yueqi | ||||||||||
| PMID: | 25664646 | ||||||||||
| 28. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2015;16(13):5343-8. | ||||||||||
| Title: | Increased Oxidative Stress and RUNX3 Hypermethylation in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma (HCC) and Induction of RUNX3 Hypermethylation by Reactive Oxygen Species in HCC Cells. | ||||||||||
| Author: | Poungpairoj, Poonsin|Whongsiri, Patcharawalai|Suwannasin, Surasit|Khlaiphuengsin, Apichaya|Tangkijvanich, Pisit|Boonla, Chanchai | ||||||||||
| PMID: | 26225676 | ||||||||||
| 29. | |||||||||||
| Journal: | Epigenetics. 2016 Aug 11:1-12. | ||||||||||
| Title: | Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. | ||||||||||
| Author: | Jueliger, Simone|Lyons, John|Cannito, Sara|Pata, Illar|Pata, Pille|Shkolnaya, Marianna|Lo Re, Oriana|Peyrou, Marion|Villarroya, Francesc|Pazienza, Valerio|Rappa, Francesca|Cappello, Francesco|Azab, Mohammad|Taverna, Pietro|Vinciguerra, Manlio | ||||||||||
| PMID: | 27646854 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 6;7(49):81255-81267. | ||||||||||
| Title: | Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Cheng|Li, Jinyun|Huang, Tao|Duan, Shiwei|Dai, Dongjun|Jiang, Danjie|Sui, Xinbing|Li, Da|Chen, Yidan|Ding, Fei|Huang, Changxin|Chen, Gongying|Wang, Kaifeng | ||||||||||
| PMID: | 27835605 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncol Rep. 2016 Dec;36(6):3379-3386. | ||||||||||
| Title: | MicroRNA-20a-5p targets RUNX3 to regulate proliferation and migration of human hepatocellular cancer cells. | ||||||||||
| Author: | Chen, Yanke|Wang, Xiaofei|Cheng, Jiwen|Wang, Zhen|Jiang, Ting|Hou, Ni|Liu, Na|Song, Tusheng|Huang, Chen | ||||||||||
| PMID: | 27748919 | ||||||||||
| 32. | |||||||||||
| Journal: | Genet Mol Res. 2016 Jun 20;15(2). pii: gmr7444. | ||||||||||
| Title: | RUNX3 promoter methylation correlation with pathogenesis of hepatocellular carcinoma in Asians. | ||||||||||
| Author: | Lu, W|Liu, Y|Liu, L-L|Zhuang, P-H | ||||||||||
| PMID: | 27420934 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 26;7(17):23825-36. | ||||||||||
| Title: | Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations. | ||||||||||
| Author: | Kim, Young-Ho|Hong, Eun-Kyung|Kong, Sun-Young|Han, Sung-Sik|Kim, Seoung-Hoon|Rhee, Je-Keun|Hwang, Soo-Kyung|Park, Sang-Jae|Kim, Tae-Min | ||||||||||
| PMID: | 27009864 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncol Rep. 2016 May;35(5):2576-82. | ||||||||||
| Title: | Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma. | ||||||||||
| Author: | Kataoka, Junro|Shiraha, Hidenori|Horiguchi, Shigeru|Sawahara, Hiroaki|Uchida, Daisuke|Nagahara, Teruya|Iwamuro, Masaya|Morimoto, Hiroki|Takeuchi, Yasuto|Kuwaki, Kenji|Onishi, Hideki|Nakamura, Shinichiro|Takaki, Akinobu|Nouso, Kazuhiro|Yagi, Takahito|Yamam | ||||||||||
| PMID: | 26985715 | ||||||||||
| 35. | |||||||||||
| Journal: | Hepatol Int. 2017 Jan;11(1):45-53. | ||||||||||
| Title: | Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics. | ||||||||||
| Author: | Khan, Faisal Saeed|Ali, Ijaz|Afridi, Ume Kalsoom|Ishtiaq, Muhammad|Mehmood, Rashid | ||||||||||
| PMID: | 27271356 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Rep. 2017 Mar;37(3):1921. | ||||||||||
| Title: | [Corrigendum] Loss of Runtrelated transcription factor 3 induces resistance to 5fluorouracil and cisplatin in hepatocellular carcinoma. | ||||||||||
| Author: | Kataoka, Junro|Shiraha, Hidenori|Horiguchi, Shigeru|Sawahara, Hiroaki|Uchida, Daisuke|Nagahara, Teruya|Iwamuro, Masaya|Morimoto, Hiroki|Takeuchi, Yasuto|Kuwaki, Kenji|Onishi, Hideki|Nakamura, Shinichiro|Takaki, Akinobu|Nouso, Kazuhiro|Yagi, Takahito|Yamam | ||||||||||
| PMID: | 28184917 | ||||||||||
| 37. | |||||||||||
| Journal: | Toxicology. 2017 Jun 15;385:1-9. | ||||||||||
| Title: | Aberrant methylation of RUNX3 is present in Aflatoxin B1-induced transformation of the L02R cell line. | ||||||||||
| Author: | Wang, Shan|He, Zhini|Li, Daochuan|Zhang, Bo|Li, Miao|Li, Wenxue|Zhu, Wei|Xing, Xiumei|Zeng, Xiaowen|Wang, Qing|Dong, Guanghui|Xiao, Yongmei|Chen, Wen|Chen, Liping | ||||||||||
| PMID: | 28458013 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 9;8(37):61475-61486. | ||||||||||
| Title: | RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR-186/E-cadherin/EMT pathway. | ||||||||||
| Author: | Gou, Yuli|Zhai, Fangbing|Zhang, Liang|Cui, Lan | ||||||||||
| PMID: | 28977878 | ||||||||||
| 39. | |||||||||||
| Journal: | Medicine (Baltimore). 2017 Oct;96(41):e8279. | ||||||||||
| Title: | Methylation analysis of p16, SLIT2, SCARA5, and Runx3 genes in hepatocellular carcinoma. | ||||||||||
| Author: | Sun, Gaofeng|Zhang, Chen|Feng, Min|Liu, Wensheng|Xie, Huifang|Qin, Qin|Zhao, E|Wan, Li | ||||||||||
| PMID: | 29019900 | ||||||||||
| 40. | |||||||||||
| Journal: | Cancer Cell Int. 2018 Apr 3;18:52. | ||||||||||
| Title: | MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer. | ||||||||||
| Author: | Pan, Chenwei|Xiang, Luxia|Pan, Zhenzhen|Wang, Xiaodong|Li, Jie|Zhuge, Lu|Fang, Peipei|Xie, Qipeng|Hu, Xuezhen | ||||||||||
| PMID: | 29636640 | ||||||||||