Primary Site >> Stomach Cancer
Gene >> RUNX3
| 1. | |||||||||||
| Journal: | Cell. 2002 Apr 5;109(1):113-24. | ||||||||||
| Title: | Causal relationship between the loss of RUNX3 expression and gastric cancer. | ||||||||||
| Author: | Li, Qing Lin|Ito, Kosei|Sakakura, Chohei|Fukamachi, Hiroshi|Inoue, Ken ichi|Chi, Xin Zi|Lee, Kwang Youl|Nomura, Shintaro|Lee, Chang Woo|Han, Sang Bae|Kim, Hwan Mook|Kim, Wun Jae|Yamamoto, Hiromitsu|Yamashita, Namiko|Yano, Takashi|Ikeda, Toshio|Itohara, Sh | ||||||||||
| PMID: | 11955451 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Cell. 2002 Apr;1(3):213-5. | ||||||||||
| Title: | RUNX: a trilogy of cancer genes. | ||||||||||
| Author: | Lund, Anders H|van Lohuizen, Maarten | ||||||||||
| PMID: | 12086855 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2002 Nov 28;21(54):8351-5. | ||||||||||
| Title: | Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. | ||||||||||
| Author: | Guo, Wei-Hui|Weng, Li-Qin|Ito, Kosei|Chen, Lin-Feng|Nakanishi, Hayao|Tatematsu, Masae|Ito, Yoshiaki | ||||||||||
| PMID: | 12447699 | ||||||||||
| 4. | |||||||||||
| Journal: | Curr Opin Genet Dev. 2003 Feb;13(1):43-7. | ||||||||||
| Title: | RUNX transcription factors as key targets of TGF-beta superfamily signaling. | ||||||||||
| Author: | Ito, Yoshiaki|Miyazono, Kohei | ||||||||||
| PMID: | 12573434 | ||||||||||
| 5. | |||||||||||
| Journal: | EMBO Rep. 2003 Jun;4(6):538-9. | ||||||||||
| Title: | Comment on Levanon et al., "Runx3 knockouts and stomach cancer", in EMBO reports (June 2003). | ||||||||||
| Author: | Bae, Suk Chul|Ito, Yoshiaki | ||||||||||
| PMID: | 12776167 | ||||||||||
| 6. | |||||||||||
| Journal: | EMBO Rep. 2003 Jun;4(6):560-4. | ||||||||||
| Title: | Runx3 knockouts and stomach cancer. | ||||||||||
| Author: | Levanon, Ditsa|Brenner, Ori|Otto, Florian|Groner, Yoram | ||||||||||
| PMID: | 12776174 | ||||||||||
| 7. | |||||||||||
| Journal: | Cell Biol Int. 2003;27(4):315-24. | ||||||||||
| Title: | Runx transcription factors and the developmental balance between cell proliferation and differentiation. | ||||||||||
| Author: | Coffman, James A | ||||||||||
| PMID: | 12788047 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Sci. 2003 Apr;94(4):360-4. | ||||||||||
| Title: | Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia. | ||||||||||
| Author: | Waki, Takayoshi|Tamura, Gen|Sato, Makoto|Terashima, Masanori|Nishizuka, Satoshi|Motoyama, Teiichi | ||||||||||
| PMID: | 12824905 | ||||||||||
| 9. | |||||||||||
| Journal: | Am J Med Genet A. 2003 Nov 1;122A(4):303-14. | ||||||||||
| Title: | Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. | ||||||||||
| Author: | Cohen, M Michael Jr | ||||||||||
| PMID: | 14518068 | ||||||||||
| 10. | |||||||||||
| Journal: | J Clin Oncol. 2003 Dec 1;21(23 Suppl):267s-269s. | ||||||||||
| Title: | Therapeutic strategies in gastric cancer. | ||||||||||
| Author: | Wong, J E L|Ito, Y|Correa, P|Peeters, K C M J|van de Velde, C J H|Sasako, M|Macdonald, J | ||||||||||
| PMID: | 14645406 | ||||||||||
| 11. | |||||||||||
| Journal: | Histol Histopathol. 2004 Jan;19(1):221-8. | ||||||||||
| Title: | Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. | ||||||||||
| Author: | Tamura, G | ||||||||||
| PMID: | 14702190 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncogene. 2004 Mar 25;23(13):2401-7. | ||||||||||
| Title: | Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines. | ||||||||||
| Author: | Wada, Manabu|Yazumi, Shujiro|Takaishi, Shigeo|Hasegawa, Kazunori|Sawada, Mitsutaka|Tanaka, Hidenori|Ida, Hiroshi|Sakakura, Chouhei|Ito, Kosei|Ito, Yoshiaki|Chiba, Tsutomu | ||||||||||
| PMID: | 14743205 | ||||||||||
| 13. | |||||||||||
| Journal: | Lab Invest. 2004 Apr;84(4):479-84. | ||||||||||
| Title: | Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma. | ||||||||||
| Author: | Kim, Tai Young|Lee, Hyeon Joo|Hwang, Kyu Sang|Lee, Minjin|Kim, Jae Won|Bang, Yung-Jue|Kang, Gyeong Hoon | ||||||||||
| PMID: | 14968123 | ||||||||||
| 14. | |||||||||||
| Journal: | J Clin Pathol. 2004 Mar;57(3):294-9. | ||||||||||
| Title: | RUNX3 expression in primary and metastatic pancreatic cancer. | ||||||||||
| Author: | Li, J|Kleeff, J|Guweidhi, A|Esposito, I|Berberat, P O|Giese, T|Buchler, M W|Friess, H | ||||||||||
| PMID: | 14990603 | ||||||||||
| 15. | |||||||||||
| Journal: | Pathobiology. 2004;71(3):137-43. | ||||||||||
| Title: | Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma. | ||||||||||
| Author: | Oshimo, Yasuhiro|Oue, Naohide|Mitani, Yoshitsugu|Nakayama, Hirofumi|Kitadai, Yasuhiko|Yoshida, Kazuhiro|Ito, Yoshiaki|Chayama, Kazuaki|Yasui, Wataru | ||||||||||
| PMID: | 15051926 | ||||||||||
| 16. | |||||||||||
| Journal: | J Biol Chem. 2004 Jul 9;279(28):29409-17. Epub 2004 May 10. | ||||||||||
| Title: | Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation. | ||||||||||
| Author: | Jin, Yun-Hye|Jeon, Eun-Joo|Li, Qing-Lin|Lee, Yong Hee|Choi, Joong-Kook|Kim, Wun-Jae|Lee, Kwang-Youl|Bae, Suk-Chul | ||||||||||
| PMID: | 15138260 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncogene. 2004 May 24;23(24):4198-208. | ||||||||||
| Title: | Oncogenic potential of the RUNX gene family: 'overview'. | ||||||||||
| Author: | Ito, Yoshiaki | ||||||||||
| PMID: | 15156173 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncogene. 2004 May 24;23(24):4232-7. | ||||||||||
| Title: | Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins. | ||||||||||
| Author: | Miyazono, Kohei|Maeda, Shingo|Imamura, Takeshi | ||||||||||
| PMID: | 15156178 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2004 May 24;23(24):4330-5. | ||||||||||
| Title: | Growth regulation of gastric epithelial cells by Runx3. | ||||||||||
| Author: | Fukamachi, Hiroshi|Ito, Kosei | ||||||||||
| PMID: | 15156189 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncogene. 2004 May 24;23(24):4336-40. | ||||||||||
| Title: | Tumor suppressor activity of RUNX3. | ||||||||||
| Author: | Bae, Suk-Chul|Choi, Joong-Kook | ||||||||||
| PMID: | 15156190 | ||||||||||
| 21. | |||||||||||
| Journal: | J Med Genet. 2004 Jun;41(6):e89. | ||||||||||
| Title: | Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients. | ||||||||||
| Author: | Keller, G|Vogelsang, H|Becker, I|Plaschke, S|Ott, K|Suriano, G|Mateus, A R|Seruca, R|Biedermann, K|Huntsman, D|Doring, C|Holinski-Feder, E|Neutzling, A|Siewert, J R|Hofler, H | ||||||||||
| PMID: | 15173255 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncogene. 2004 Sep 2;23(40):6736-42. | ||||||||||
| Title: | Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. | ||||||||||
| Author: | Ku, Ja-Lok|Kang, Sung-Bum|Shin, Young-Kyoung|Kang, Hio Chung|Hong, Sung-Hye|Kim, Il-Jin|Shin, Joo-Ho|Han, Inn-Oc|Park, Jae-Gahb | ||||||||||
| PMID: | 15273736 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pathol. 2004 Sep;204(1):75-83. | ||||||||||
| Title: | Early-onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age. | ||||||||||
| Author: | Carvalho, Ralph|Milne, Anya N A|van Rees, Bastiaan P|Caspers, Eric|Cirnes, Luis|Figueiredo, Ceu|Offerhaus, G Johan A|Weterman, Marian A J | ||||||||||
| PMID: | 15307140 | ||||||||||
| 24. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2004 Aug 13;321(1):58-64. | ||||||||||
| Title: | Runx3-/- gastric epithelial cells differentiate into intestinal type cells. | ||||||||||
| Author: | Fukamachi, Hiroshi|Ito, Kosei|Ito, Yoshiaki | ||||||||||
| PMID: | 15358215 | ||||||||||
| 25. | |||||||||||
| Journal: | Eur J Clin Invest. 2004 Sep;34(9):605-12. | ||||||||||
| Title: | Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinoma. | ||||||||||
| Author: | Osaki, M|Moriyama, M|Adachi, K|Nakada, C|Takeda, A|Inoue, Y|Adachi, H|Sato, K|Oshimura, M|Ito, H | ||||||||||
| PMID: | 15379759 | ||||||||||
| 26. | |||||||||||
| Journal: | Ai Zheng. 2004 Nov;23(11):1354-6. | ||||||||||
| Title: | [Improvement and application of methylation-specific polymerase chain reaction]. | ||||||||||
| Author: | Xiao, Wen-Hua|Liu, Wei-Wen | ||||||||||
| PMID: | 15522190 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2005 Jan 10;113(2):221-8. | ||||||||||
| Title: | Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer. | ||||||||||
| Author: | Sakakura, Chouhei|Hagiwara, Akeo|Miyagawa, Koji|Nakashima, Susumu|Yoshikawa, Tetsuji|Kin, Shuichi|Nakase, Yuenn|Ito, Kosei|Yamagishi, Hisakazu|Yazumi, Shujiro|Chiba, Tsutomu|Ito, Yoshiaki | ||||||||||
| PMID: | 15386419 | ||||||||||
| 28. | |||||||||||
| Journal: | Br J Cancer. 2005 Feb 14;92(3):562-9. | ||||||||||
| Title: | Frequent loss of RUNX3 gene expression in remnant stomach cancer and adjacent mucosa with special reference to topography. | ||||||||||
| Author: | Nakase, Y|Sakakura, C|Miyagawa, K|Kin, S|Fukuda, K|Yanagisawa, A|Koide, K|Morofuji, N|Hosokawa, Y|Shimomura, K|Katsura, K|Hagiwara, A|Yamagishi, H|Ito, K|Ito, Y | ||||||||||
| PMID: | 15685235 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncogene. 2005 Mar 31;24(14):2354-66. | ||||||||||
| Title: | Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma. | ||||||||||
| Author: | Zavros, Yana|Eaton, Kathryn A|Kang, Weiqun|Rathinavelu, Sivaprakash|Katukuri, Vinay|Kao, John Y|Samuelson, Linda C|Merchant, Juanita L | ||||||||||
| PMID: | 15735748 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Cancer. 2005 Aug 10;116(1):155-60. | ||||||||||
| Title: | Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1. | ||||||||||
| Author: | Guo, Changcun|Ding, Jie|Yao, Liping|Sun, Li|Lin, Tao|Song, Ying|Sun, Lijun|Fan, Daiming | ||||||||||
| PMID: | 15756676 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Res. 2005 Jun 1;65(11):4809-16. | ||||||||||
| Title: | Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis. | ||||||||||
| Author: | Wei, Daoyan|Gong, Weida|Oh, Sang C|Li, Qiang|Kim, Won Dong|Wang, Liwei|Le, Xiangdong|Yao, James|Wu, Tsung T|Huang, Suyun|Xie, Keping | ||||||||||
| PMID: | 15930301 | ||||||||||
| 32. | |||||||||||
| Journal: | Anticancer Res. 2005 Jul-Aug;25(4):2627-30. | ||||||||||
| Title: | RUNX3 promoter region is specifically methylated in poorly-differentiated colorectal cancer. | ||||||||||
| Author: | Imamura, Yasuhiro|Hibi, Kenji|Koike, Masahiko|Fujiwara, Michitaka|Kodera, Yasuhiro|Ito, Katsuki|Nakao, Akimasa | ||||||||||
| PMID: | 16080503 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncogene. 2005 Dec 15;24(56):8252-8. | ||||||||||
| Title: | Exclusion of RUNX3 as a tumour-suppressor gene in early-onset gastric carcinomas. | ||||||||||
| Author: | Carvalho, Ralph|Milne, Anya N A|Polak, Mirjam|Corver, Willem E|Offerhaus, G Johan A|Weterman, Marian A J | ||||||||||
| PMID: | 16091737 | ||||||||||
| 34. | |||||||||||
| Journal: | Mol Cell Biol. 2005 Sep;25(18):8097-107. | ||||||||||
| Title: | RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD. | ||||||||||
| Author: | Chi, Xin-Zi|Yang, Jeung-Ook|Lee, Kwang-Youl|Ito, Kosei|Sakakura, Chohei|Li, Qing-Lin|Kim, Hye-Ryun|Cha, Eun-Jeung|Lee, Yong-Hee|Kaneda, Atsushi|Ushijima, Toshikazu|Kim, Wun-Jae|Ito, Yoshiaki|Bae, Suk-Chul | ||||||||||
| PMID: | 16135801 | ||||||||||
| 35. | |||||||||||
| Journal: | Cancer Res. 2005 Sep 1;65(17):7743-50. | ||||||||||
| Title: | RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. | ||||||||||
| Author: | Ito, Kosei|Liu, Qiang|Salto-Tellez, Manuel|Yano, Takashi|Tada, Kotaro|Ida, Hiroshi|Huang, Canhua|Shah, Nilesh|Inoue, Masafumi|Rajnakova, Andrea|Hiong, Kum Chew|Peh, Bee Keow|Han, Hwan Chour|Ito, Tomoko|Teh, Ming|Yeoh, Khay Guan|Ito, Yoshiaki | ||||||||||
| PMID: | 16140942 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Rep. 2005 Oct;14(4):817-22. | ||||||||||
| Title: | Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines. | ||||||||||
| Author: | Yanada, Masashi|Yaoi, Takeshi|Shimada, Junichi|Sakakura, Chouhei|Nishimura, Motohiro|Ito, Kazuhiro|Terauchi, Kunihiko|Nishiyama, Katsuhiko|Itoh, Kyoko|Fushiki, Shinji | ||||||||||
| PMID: | 16142337 | ||||||||||
| 37. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Sep 15;11(18):6479-88. | ||||||||||
| Title: | Possible involvement of RUNX3 silencing in the peritoneal metastases of gastric cancers. | ||||||||||
| Author: | Sakakura, Chouhei|Hasegawa, Kazunori|Miyagawa, Koji|Nakashima, Susumu|Yoshikawa, Tetsuji|Kin, Shuichi|Nakase, Yuenn|Yazumi, Shujiro|Yamagishi, Hisakazu|Okanoue, Takeshi|Chiba, Tsutomu|Hagiwara, Akeo | ||||||||||
| PMID: | 16166423 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Res. 2005 Oct 15;65(20):9347-54. | ||||||||||
| Title: | RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. | ||||||||||
| Author: | Kim, Wun-Jae|Kim, Eun-Jung|Jeong, Pildu|Quan, Changyi|Kim, Jiyeon|Li, Qing-Lin|Yang, Jeong-Ook|Ito, Yoshiaki|Bae, Suk-Chul | ||||||||||
| PMID: | 16230397 | ||||||||||
| 39. | |||||||||||
| Journal: | J Cell Physiol. 2006 Feb;206(2):354-62. | ||||||||||
| Title: | Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2. | ||||||||||
| Author: | Pockwinse, Shirwin M|Rajgopal, Arun|Young, Daniel W|Mujeeb, Khwaja A|Nickerson, Jeffrey|Javed, Amjad|Redick, Sambra|Lian, Jane B|van Wijnen, Andre J|Stein, Janet L|Stein, Gary S|Doxsey, Stephen J | ||||||||||
| PMID: | 16110492 | ||||||||||
| 40. | |||||||||||
| Journal: | Cancer Sci. 2006 Jan;97(1):51-6. | ||||||||||
| Title: | Spreading of methylation within RUNX3 CpG island in gastric cancer. | ||||||||||
| Author: | Homma, Naoyuki|Tamura, Gen|Honda, Teiichiro|Matsumoto, Yutaka|Nishizuka, Satoshi|Kawata, Sumio|Motoyama, Teiichi | ||||||||||
| PMID: | 16367921 | ||||||||||
| 41. | |||||||||||
| Journal: | J Biol Chem. 2006 Feb 24;281(8):5267-76. Epub 2005 Dec 22. | ||||||||||
| Title: | RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells. | ||||||||||
| Author: | Yamamura, Yasuko|Lee, Wei Lin|Inoue, Ken-ichi|Ida, Hiroshi|Ito, Yoshiaki | ||||||||||
| PMID: | 16373335 | ||||||||||
| 42. | |||||||||||
| Journal: | World J Gastroenterol. 2006 Jan 14;12(2):192-8. | ||||||||||
| Title: | Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. | ||||||||||
| Author: | Tamura, Gen | ||||||||||
| PMID: | 16482617 | ||||||||||
| 43. | |||||||||||
| Journal: | World J Gastroenterol. 2006 Mar 21;12(11):1671-80. | ||||||||||
| Title: | Helicobacter pylori eradication to prevent gastric cancer: underlying molecular and cellular mechanisms. | ||||||||||
| Author: | Tsuji, Shingo|Tsujii, Masahiko|Murata, Hiroaki|Nishida, Tsutomu|Komori, Masato|Yasumaru, Masakazu|Ishii, Shuji|Sasayama, Yoshiaki|Kawano, Sunao|Hayashi, Norio | ||||||||||
| PMID: | 16586533 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Biol Ther. 2006 Apr;5(4):371-4. Epub 2006 Apr 30. | ||||||||||
| Title: | How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions. | ||||||||||
| Author: | Vogiatzi, Paraskevi|De Falco, Giulia|Claudio, Pier Paolo|Giordano, Antonio | ||||||||||
| PMID: | 16627973 | ||||||||||
| 45. | |||||||||||
| Journal: | Mol Cell Biol. 2006 Jun;26(12):4474-88. | ||||||||||
| Title: | The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis. | ||||||||||
| Author: | Yano, Takashi|Ito, Kosei|Fukamachi, Hiroshi|Chi, Xin-Zi|Wee, Hee-Jun|Inoue, Ken-ichi|Ida, Hiroshi|Bouillet, Philippe|Strasser, Andreas|Bae, Suk-Chul|Ito, Yoshiaki | ||||||||||
| PMID: | 16738314 | ||||||||||
| 46. | |||||||||||
| Journal: | Anat Rec A Discov Mol Cell Evol Biol. 2006 Jul;288(7):695-9. | ||||||||||
| Title: | Runx3 expression during mouse tongue and palate development. | ||||||||||
| Author: | Yamamoto, Hiromitsu|Ito, Kosei|Kawai, Mariko|Murakami, Yota|Bessho, Kazuhisa|Ito, Yoshiaki | ||||||||||
| PMID: | 16761282 | ||||||||||
| 47. | |||||||||||
| Journal: | J Pathol. 2006 Oct;210(2):141-6. | ||||||||||
| Title: | Lack of RUNX3 regulation in human gastric cancer. | ||||||||||
| Author: | Friedrich, M J|Rad, R|Langer, R|Voland, P|Hoefler, H|Schmid, R M|Prinz, C|Gerhard, M | ||||||||||
| PMID: | 16917803 | ||||||||||
| 48. | |||||||||||
| Journal: | Gastric Cancer. 2006;9(3):156-66. | ||||||||||
| Title: | Gastric-and-intestinal mixed-type intestinal metaplasia: aberrant expression of transcription factors and stem cell intestinalization. | ||||||||||
| Author: | Tsukamoto, Tetsuya|Mizoshita, Tsutomu|Tatematsu, Masae | ||||||||||
| PMID: | 16952033 | ||||||||||
| 49. | |||||||||||
| Journal: | Cancer Sci. 2006 Nov;97(11):1155-8. Epub 2006 Sep 5. | ||||||||||
| Title: | Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. | ||||||||||
| Author: | So, Kanji|Tamura, Gen|Honda, Teiichiro|Homma, Naoyuki|Waki, Takayoshi|Togawa, Naoyuki|Nishizuka, Satoshi|Motoyama, Teiichi | ||||||||||
| PMID: | 16952303 | ||||||||||
| 50. | |||||||||||
| Journal: | Int J Oncol. 2006 Oct;29(4):779-84. | ||||||||||
| Title: | Expression status of RUNX1/AML1 in normal gastric epithelium and its mutational analysis in microdissected gastric cancer cells. | ||||||||||
| Author: | Usui, Takebumi|Aoyagi, Kazuhiko|Saeki, Norihisa|Nakanishi, Yukihiro|Kanai, Yae|Ohki, Misao|Ogawa, Kenji|Yoshida, Teruhiko|Sasaki, Hiroki | ||||||||||
| PMID: | 16964375 | ||||||||||
| 51. | |||||||||||
| Journal: | Pathol Int. 2006 Oct;56(10):571-5. | ||||||||||
| Title: | Quantitative assessment of RUNX3 methylation in neoplastic and non-neoplastic gastric epithelia using a DNA microarray. | ||||||||||
| Author: | So, Kanji|Tamura, Gen|Honda, Teiichiro|Homma, Naoyuki|Endoh, Makoto|Togawa, Naoyuki|Nishizuka, Satoshi|Motoyama, Teiichi | ||||||||||
| PMID: | 16984612 | ||||||||||
| 52. | |||||||||||
| Journal: | Clin Cancer Res. 2006 Nov 1;12(21):6386-94. | ||||||||||
| Title: | RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer. | ||||||||||
| Author: | Peng, Zhihai|Wei, Daoyan|Wang, Liwei|Tang, Huamei|Zhang, Jun|Le, Xiangdong|Jia, Zhiliang|Li, Qiang|Xie, Keping | ||||||||||
| PMID: | 17085650 | ||||||||||
| 53. | |||||||||||
| Journal: | Int J Mol Med. 2006 Dec;18(6):1019-23. | ||||||||||
| Title: | Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review). | ||||||||||
| Author: | Katoh, Yuriko|Katoh, Masaru | ||||||||||
| PMID: | 17089004 | ||||||||||
| 54. | |||||||||||
| Journal: | Anticancer Res. 2006 Sep-Oct;26(5B):3633-43. | ||||||||||
| Title: | Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis. | ||||||||||
| Author: | Miyagawa, Kouji|Sakakura, Chouhei|Nakashima, Susumu|Yoshikawa, Tetsuji|Kin, Shuichi|Nakase, Yuenn|Ito, Kosei|Yamagishi, Hisakazu|Ida, Hiroshi|Yazumi, Shujiro|Chiba, Tsutomu|Ito, Yoshiaki|Hagiwara, Akeo | ||||||||||
| PMID: | 17094378 | ||||||||||
| 55. | |||||||||||
| Journal: | Oral Oncol. 2007 Jan;43(1):88-94. Epub 2006 Jun 22. | ||||||||||
| Title: | Runt-related transcription factor 3 expression in human oral squamous cell carcinomas; implication for tumor progression and prognosis. | ||||||||||
| Author: | Tanji, Yoshiyuki|Osaki, Mitsuhiko|Nagahama, Yumi|Kodani, Isamu|Ryoke, Kazuo|Ito, Hisao | ||||||||||
| PMID: | 16798064 | ||||||||||
| 56. | |||||||||||
| Journal: | Biochem Pharmacol. 2007 Apr 1;73(7):990-1000. Epub 2006 Dec 16. | ||||||||||
| Title: | Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment. | ||||||||||
| Author: | Huang, Canhua|Ida, Hiroshi|Ito, Kosei|Zhang, Haiyuan|Ito, Yoshiaki | ||||||||||
| PMID: | 17276407 | ||||||||||
| 57. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Mar;10(2):165-8. | ||||||||||
| Title: | [Reappraisal of the impacts of human Runt-related transcription factor gene 3 expression on differentiation and prognosis of gastric cancer]. | ||||||||||
| Author: | Wu, Bei-wen|Zhang, Jun|Fei, Xu-feng|Zhu, Zheng-gang|Cao, Wei-xin | ||||||||||
| PMID: | 17380460 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncogene. 2007 Aug 30;26(40):5927-38. Epub 2007 Mar 26. | ||||||||||
| Title: | Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis. | ||||||||||
| Author: | Sakakura, C|Miyagawa, K|Fukuda, K-I|Nakashima, S|Yoshikawa, T|Kin, S|Nakase, Y|Ida, H|Yazumi, S|Yamagishi, H|Okanoue, T|Chiba, T|Ito, K|Hagiwara, A|Ito, Y | ||||||||||
| PMID: | 17384682 | ||||||||||
| 59. | |||||||||||
| Journal: | Oncogene. 2007 Oct 4;26(45):6488-98. Epub 2007 Apr 30. | ||||||||||
| Title: | GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling. | ||||||||||
| Author: | Saeki, N|Kim, D H|Usui, T|Aoyagi, K|Tatsuta, T|Aoki, K|Yanagihara, K|Tamura, M|Mizushima, H|Sakamoto, H|Ogawa, K|Ohki, M|Shiroishi, T|Yoshida, T|Sasaki, H | ||||||||||
| PMID: | 17471240 | ||||||||||
| 60. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Jun;6(6):832-9. Epub 2007 Mar 26. | ||||||||||
| Title: | Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 17568183 | ||||||||||
| 61. | |||||||||||
| Journal: | J Mol Med (Berl). 2007 Oct;85(10):1137-48. Epub 2007 Jun 15. | ||||||||||
| Title: | Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. | ||||||||||
| Author: | Jung, Yeonjoo|Park, Jinah|Kim, Tai Young|Park, Jung-Hyun|Jong, Hyun-Soon|Im, Seock-Ah|Robertson, Keith D|Bang, Yung-Jue|Kim, Tae-You | ||||||||||
| PMID: | 17571247 | ||||||||||
| 62. | |||||||||||
| Journal: | Ann Oncol. 2007 Jun;18 Suppl 6:vi103-9. | ||||||||||
| Title: | Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. | ||||||||||
| Author: | Gargano, G|Calcara, D|Corsale, S|Agnese, V|Intrivici, C|Fulfaro, F|Pantuso, G|Cajozzo, M|Morello, V|Tomasino, R M|Ottini, L|Colucci, G|Bazan, V|Russo, A | ||||||||||
| PMID: | 17591800 | ||||||||||
| 63. | |||||||||||
| Journal: | Exp Cell Res. 2007 Sep 10;313(15):3251-60. Epub 2007 Jun 29. | ||||||||||
| Title: | Runx3 interacts with DNA repair protein Ku70. | ||||||||||
| Author: | Tanaka, Yasuo|Imamura, Jun|Kanai, Fumihiko|Ichimura, Tohru|Isobe, Toshiaki|Koike, Manabu|Kudo, Yotaro|Tateishi, Keisuke|Ikenoue, Tsuneo|Ijichi, Hideaki|Yamaji, Yutaka|Yoshida, Haruhiko|Kawabe, Takao|Omata, Masao | ||||||||||
| PMID: | 17662272 | ||||||||||
| 64. | |||||||||||
| Journal: | J Gastroenterol. 2007 Nov;42(11):866-73. Epub 2007 Nov 22. | ||||||||||
| Title: | Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients. | ||||||||||
| Author: | Mitsuno, Mayumi|Kitajima, Yoshihiko|Ide, Takao|Ohtaka, Kazuma|Tanaka, Masayuki|Satoh, Seiji|Miyazaki, Kohji | ||||||||||
| PMID: | 18008030 | ||||||||||
| 65. | |||||||||||
| Journal: | Cancer Sci. 2008 Jan;99(1):23-30. Epub 2007 Oct 22. | ||||||||||
| Title: | Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1. | ||||||||||
| Author: | Nagahama, Yumi|Ishimaru, Mika|Osaki, Mitsuhiko|Inoue, Toshiaki|Maeda, Akihiro|Nakada, Chisato|Moriyama, Masatsugu|Sato, Kenzo|Oshimura, Mitsuo|Ito, Hisao | ||||||||||
| PMID: | 17956589 | ||||||||||
| 66. | |||||||||||
| Journal: | Adv Cancer Res. 2008;99:33-76. | ||||||||||
| Title: | RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes. | ||||||||||
| Author: | Ito, Yoshiaki | ||||||||||
| PMID: | 18037406 | ||||||||||
| 67. | |||||||||||
| Journal: | Oncol Rep. 2008 Jan;19(1):197-202. | ||||||||||
| Title: | Helicobacter pylori infection is an independent risk factor for Runx3 methylation in gastric cancer. | ||||||||||
| Author: | Kitajima, Yoshihiko|Ohtaka, Kazuma|Mitsuno, Mayumi|Tanaka, Masayuki|Sato, Seiji|Nakafusa, Yuji|Miyazaki, Kohji | ||||||||||
| PMID: | 18097595 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncol Rep. 2008 Mar;19(3):713-9. | ||||||||||
| Title: | Decreased expression of RUNX3 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma. | ||||||||||
| Author: | Sugiura, Hironori|Ishiguro, Hideyuki|Kuwabara, Yoshiyuki|Kimura, Masahiro|Mitsui, Akira|Mori, Yoichiro|Ogawa, Ryo|Katada, Takeyasu|Harata, Koshiro|Fujii, Yoshitaka | ||||||||||
| PMID: | 18288406 | ||||||||||
| 69. | |||||||||||
| Journal: | Dig Liver Dis. 2008 Jul;40(7):510-22. | ||||||||||
| Title: | Biology of intestinal metaplasia in 2008: more than a simple phenotypic alteration. | ||||||||||
| Author: | Gutierrez-Gonzalez, L|Wright, N A | ||||||||||
| PMID: | 18400571 | ||||||||||
| 70. | |||||||||||
| Journal: | Cancer Sci. 2008 Jul;99(7):1334-40. | ||||||||||
| Title: | Expression of RUNX3 in salivary adenoid cystic carcinoma: implications for tumor progression and prognosis. | ||||||||||
| Author: | He, Jian-Feng|Ge, Ming-Hua|Zhu, Xin|Chen, Chao|Tan, Zhuo|Li, Yi-Ning|Gu, Zhi-Yuan | ||||||||||
| PMID: | 18410404 | ||||||||||
| 71. | |||||||||||
| Journal: | J Biol Chem. 2008 Jun 20;283(25):17324-32. | ||||||||||
| Title: | Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. | ||||||||||
| Author: | Fujii, Satoshi|Ito, Kosei|Ito, Yoshiaki|Ochiai, Atsushi | ||||||||||
| PMID: | 18430739 | ||||||||||
| 72. | |||||||||||
| Journal: | World J Gastroenterol. 2008 May 21;14(19):3006-14. | ||||||||||
| Title: | Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro. | ||||||||||
| Author: | Feng, Xue-Zhi|He, Xiu-Sheng|Zhuang, Ying-Zhi|Luo, Qiao|Jiang, Jun-Hao|Yang, Shuai|Tang, Xue-Fang|Liu, Ju-Lin|Chen, Tao | ||||||||||
| PMID: | 18494051 | ||||||||||
| 73. | |||||||||||
| Journal: | J Surg Oncol. 2008 Aug 1;98(2):124-9. | ||||||||||
| Title: | Clinicopathological and prognostic significance of mucin phenotype in gastric cancer. | ||||||||||
| Author: | Wakatsuki, Kohei|Yamada, Yukishige|Narikiyo, Michihiro|Ueno, Masato|Takayama, Tomoyoshi|Tamaki, Hidetoshi|Miki, Katsuhiko|Matsumoto, Sohei|Enomoto, Koji|Yokotani, Tomoyo|Nakajima, Yoshiyuki | ||||||||||
| PMID: | 18521835 | ||||||||||
| 74. | |||||||||||
| Journal: | J Cell Biochem. 2008 Sep 1;105(1):236-44. | ||||||||||
| Title: | E1A physically interacts with RUNX3 and inhibits its transactivation activity. | ||||||||||
| Author: | Cha, Eun-Jeong|Oh, Byung-Chul|Wee, Hee-Jun|Chi, Xin-Zi|Goh, Yun-Mi|Lee, Kyeong-Sook|Ito, Yoshiaki|Bae, Suk-Chul | ||||||||||
| PMID: | 18570183 | ||||||||||
| 75. | |||||||||||
| Journal: | Pathobiology. 2008;75(4):244-51. | ||||||||||
| Title: | Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines. | ||||||||||
| Author: | Jiang, Ying|Tong, Dandan|Lou, Ge|Zhang, Ying|Geng, Jingshu | ||||||||||
| PMID: | 18580070 | ||||||||||
| 76. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Jul;11(4):379-82. | ||||||||||
| Title: | [Promoter methylation and expression of Runx3 gene in gastric cancer]. | ||||||||||
| Author: | Li, Li-Yi|Li, Ji-Kun|Shen, Yun|Yu, Liang|Zhang, Jian-Hai | ||||||||||
| PMID: | 18636364 | ||||||||||
| 77. | |||||||||||
| Journal: | Cancer Cell. 2008 Sep 9;14(3):226-37. | ||||||||||
| Title: | RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis. | ||||||||||
| Author: | Ito, Kosei|Lim, Anthony Chee-Beng|Salto-Tellez, Manuel|Motoda, Lena|Osato, Motomi|Chuang, Linda Shyue Huey|Lee, Cecilia Wei Lin|Voon, Dominic Chih-Cheng|Koo, Jason Kin Wai|Wang, Huajing|Fukamachi, Hiroshi|Ito, Yoshiaki | ||||||||||
| PMID: | 18772112 | ||||||||||
| 78. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Oct 1;14(19):6264-9. | ||||||||||
| Title: | Reprimo as a potential biomarker for early detection in gastric cancer. | ||||||||||
| Author: | Bernal, Carolina|Aguayo, Francisco|Villarroel, Cynthia|Vargas, Macarena|Diaz, Ignacio|Ossandon, Francisco J|Santibanez, Eudocia|Palma, Mariana|Aravena, Edmundo|Barrientos, Carlos|Corvalan, Alejandro H | ||||||||||
| PMID: | 18829507 | ||||||||||
| 79. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2008 May;30(5):361-4. | ||||||||||
| Title: | [Relationship between Runx3 gene expression and its DNA methylation in gastric cancer]. | ||||||||||
| Author: | Gao, Nan|Chen, Wei-Chang|Cen, Jian-Nong | ||||||||||
| PMID: | 18953836 | ||||||||||
| 80. | |||||||||||
| Journal: | Gut Liver. 2008 Sep;2(2):119-25. | ||||||||||
| Title: | Methylation of the Tumor Suppressor Gene RUNX3 in Human Gastric Carcinoma. | ||||||||||
| Author: | Song, Hyun Joo|Shim, Ki-Nam|Joo, Yang-Hee|Kim, Seong-Eun|Jung, Sung-Ae|Yoo, Kwon | ||||||||||
| PMID: | 20485621 | ||||||||||
| 81. | |||||||||||
| Journal: | Oncogene. 2009 Jan 15;28(2):184-94. | ||||||||||
| Title: | Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. | ||||||||||
| Author: | Lee, S H|Kim, J|Kim, W-H|Lee, Y M | ||||||||||
| PMID: | 18850007 | ||||||||||
| 82. | |||||||||||
| Journal: | Histol Histopathol. 2009 Jan;24(1):31-40. | ||||||||||
| Title: | RUNX3 expression correlates with chief cell differentiation in human gastric cancers. | ||||||||||
| Author: | Ogasawara, N|Tsukamoto, T|Mizoshita, T|Inada, K-I|Ban, H|Kondo, S|Takasu, S|Ushijima, T|Ito, K|Ito, Y|Ichinose, M|Ogawa, T|Joh, T|Tatematsu, M | ||||||||||
| PMID: | 19012242 | ||||||||||
| 83. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2009 Jan;24(1):37-41. | ||||||||||
| Title: | |||||||||||