Primary Site >> Colorectal Cancer
Gene >> RSPO1
| 1. | |||||||||||
| Journal: | Nature. 2012 Aug 30;488(7413):660-4. | ||||||||||
| Title: | Recurrent R-spondin fusions in colon cancer. | ||||||||||
| Author: | Seshagiri, Somasekar|Stawiski, Eric W|Durinck, Steffen|Modrusan, Zora|Storm, Elaine E|Conboy, Caitlin B|Chaudhuri, Subhra|Guan, Yinghui|Janakiraman, Vasantharajan|Jaiswal, Bijay S|Guillory, Joseph|Ha, Connie|Dijkgraaf, Gerrit J P|Stinson, Jeremy|Gnad, Flo | ||||||||||
| PMID: | 22895193 | ||||||||||
| 2. | |||||||||||
| Journal: | PLoS One. 2012;7(5):e37137. | ||||||||||
| Title: | LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor. | ||||||||||
| Author: | Gong, Xing|Carmon, Kendra S|Lin, Qiushi|Thomas, Anthony|Yi, Jing|Liu, Qingyun | ||||||||||
| PMID: | 22615920 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2013 Feb;144(2):381-91. | ||||||||||
| Title: | Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells. | ||||||||||
| Author: | Fafilek, Bohumil|Krausova, Michaela|Vojtechova, Martina|Pospichalova, Vendula|Tumova, Lucie|Sloncova, Eva|Huranova, Martina|Stancikova, Jitka|Hlavata, Adela|Svec, Jiri|Sedlacek, Radislav|Luksan, Ondrej|Oliverius, Martin|Voska, Ludek|Jirsa, Milan|Paces, Ja | ||||||||||
| PMID: | 23142137 | ||||||||||
| 4. | |||||||||||
| Journal: | Front Oncol. 2013 Apr 15;3:81. | ||||||||||
| Title: | LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/beta-Catenin Signaling. | ||||||||||
| Author: | Scannell, Christopher A|Pedersen, Elisabeth A|Mosher, Jack T|Krook, Melanie Anne|Nicholls, Lauren A|Wilky, Breelyn A|Loeb, David M|Lawlor, Elizabeth R | ||||||||||
| PMID: | 23596566 | ||||||||||
| 5. | |||||||||||
| Journal: | Protein Sci. 2014 May;23(5):551-65. | ||||||||||
| Title: | Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells. | ||||||||||
| Author: | Kumar, Kaavya Krishna|Burgess, Antony W|Gulbis, Jacqueline M | ||||||||||
| PMID: | 24677446 | ||||||||||
| 6. | |||||||||||
| Journal: | Mol Biol Rep. 2014 Aug;41(8):5375-84. | ||||||||||
| Title: | RSPO fusion transcripts in colorectal cancer in Japanese population. | ||||||||||
| Author: | Shinmura, Kazuya|Kahyo, Tomoaki|Kato, Hisami|Igarashi, Hisaki|Matsuura, Shun|Nakamura, Satoki|Kurachi, Kiyotaka|Nakamura, Toshio|Ogawa, Hiroshi|Funai, Kazuhito|Tanahashi, Masayuki|Niwa, Hiroshi|Sugimura, Haruhiko | ||||||||||
| PMID: | 24847761 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2015 Sep 3;34(36):4692-701. | ||||||||||
| Title: | Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. | ||||||||||
| Author: | Gong, X|Yi, J|Carmon, K S|Crumbley, C A|Xiong, W|Thomas, A|Fan, X|Guo, S|An, Z|Chang, J T|Liu, Q J | ||||||||||
| PMID: | 25531322 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell. 2015 May 7;161(4):933-45. | ||||||||||
| Title: | Prospective derivation of a living organoid biobank of colorectal cancer patients. | ||||||||||
| Author: | van de Wetering, Marc|Francies, Hayley E|Francis, Joshua M|Bounova, Gergana|Iorio, Francesco|Pronk, Apollo|van Houdt, Winan|van Gorp, Joost|Taylor-Weiner, Amaro|Kester, Lennart|McLaren-Douglas, Anne|Blokker, Joyce|Jaksani, Sridevi|Bartfeld, Sina|Volckman, | ||||||||||
| PMID: | 25957691 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2016 Apr 28;35(17):2197-207. | ||||||||||
| Title: | Wnt addiction of genetically defined cancers reversed by PORCN inhibition. | ||||||||||
| Author: | Madan, B|Ke, Z|Harmston, N|Ho, S Y|Frois, A O|Alam, J|Jeyaraj, D A|Pendharkar, V|Ghosh, K|Virshup, I H|Manoharan, V|Ong, E H Q|Sangthongpitag, K|Hill, J|Petretto, E|Keller, T H|Lee, M A|Matter, A|Virshup, D M | ||||||||||
| PMID: | 26257057 | ||||||||||
| 10. | |||||||||||
| Journal: | Methods Mol Biol. 2016 Aug 19. | ||||||||||
| Title: | Murine Colonic Organoid Culture System and Downstream Assay Applications. | ||||||||||
| Author: | Fan, Yang-Yi|Davidson, Laurie A|Chapkin, Robert S | ||||||||||
| PMID: | 27539462 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Res. 2016 Sep;14(9):859-68. | ||||||||||
| Title: | Novel Bispecific Domain Antibody to LRP6 Inhibits Wnt and R-spondin Ligand-Induced Wnt Signaling and Tumor Growth. | ||||||||||
| Author: | Jackson, Heather|Granger, David|Jones, Gavin|Anderson, Louisa|Friel, Sarah|Rycroft, Daniel|Fieles, William|Tunstead, James|Steward, Michael|Wattam, Trevor|Walker, Adam|Griggs, Jeremy|Al-Hajj, Muhammad|Shelton, Christopher | ||||||||||
| PMID: | 27401612 | ||||||||||
| 12. | |||||||||||
| Journal: | Gut. 2017 Jun;66(6):1095-1105. | ||||||||||
| Title: | RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis. | ||||||||||
| Author: | Hilkens, John|Timmer, Nikki C|Boer, Mandy|Ikink, Gerjon J|Schewe, Matthias|Sacchetti, Andrea|Koppens, Martijn A J|Song, Ji-Ying|Bakker, Elvira R M | ||||||||||
| PMID: | 27511199 | ||||||||||
| 13. | |||||||||||
| Journal: | Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 May 28;42(5):501-506. | ||||||||||
| Title: | [Expression of regulatory factor R-spondin family in Wnt signaling pathway in colorectal cancer and its clinical significance]. | ||||||||||
| Author: | Liu, Heli|Zhou, Yuan|Tan, Fengbo|Wang, Yinan|Pei, Haiping | ||||||||||
| PMID: | 28626093 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2017 Sep 8;292(36):14989-15001. | ||||||||||
| Title: | LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway. | ||||||||||
| Author: | Carmon, Kendra S|Gong, Xing|Yi, Jing|Wu, Ling|Thomas, Anthony|Moore, Catherine M|Masuho, Ikuo|Timson, David J|Martemyanov, Kirill A|Liu, Qingyun J | ||||||||||
| PMID: | 28739799 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Res. 2017 Dec 1;77(23):6589-6602. | ||||||||||
| Title: | R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis. | ||||||||||
| Author: | Zhou, Xiaolin|Geng, Liying|Wang, Degeng|Yi, Haowei|Talmon, Geoffrey|Wang, Jing | ||||||||||
| PMID: | 28939678 | ||||||||||
| 16. | |||||||||||
| Journal: | Sci Rep. 2017 Nov 10;7(1):15270. | ||||||||||
| Title: | RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations. | ||||||||||
| Author: | Fischer, Marcus M|Yeung, V Pete|Cattaruzza, Fiore|Hussein, Rajaa|Yen, Wan-Ching|Murriel, Christopher|Evans, James W|O'Young, Gilbert|Brunner, Alayne L|Wang, Min|Cain, Jennifer|Cancilla, Belinda|Kapoun, Ann|Hoey, Timothy | ||||||||||
| PMID: | 29127379 | ||||||||||
| 17. | |||||||||||
| Journal: | Genes (Basel). 2018 Jan 8;9(1). pii: genes9010020. | ||||||||||
| Title: | Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells. | ||||||||||
| Author: | Kriz, Vitezslav|Korinek, Vladimir | ||||||||||
| PMID: | 29316729 | ||||||||||