Primary Site >> Colorectal Cancer

Gene >> RRM1

Journal: J Biol Chem. 2004 Jun 25;279(26):27030-8.
Title: Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.
Author: Lin, Z Ping|Belcourt, Michael F|Cory, Joseph G|Sartorelli, Alan C
PMID: 15096505
Journal: Cancer Res. 2005 Oct 15;65(20):9510-6.
Title: In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
Author: Bergman, Andries M|Eijk, Paul P|Ruiz van Haperen, Veronique W T|Smid, Kees|Veerman, Gijsbert|Hubeek, Isabelle|van den Ijssel, Paul|Ylstra, Bauke|Peters, Godefridus J
PMID: 16230416
Journal: Cancer Res. 2005 Nov 15;65(22):10208-13.
Title: Expression microarray analysis and oligo array comparative genomic hybridization of acquired gemcitabine resistance in mouse colon reveals selection for chromosomal aberrations.
Author: van de Wiel, Mark A|Costa, Jose L|Smid, Kees|Oudejans, Cees B M|Bergman, Andries M|Meijer, Gerrit A|Peters, Godefridus J|Ylstra, Bauke
PMID: 16288008
Journal: Chemotherapy. 2006;52(1):20-2.
Title: What is the best sequence of chemotherapy in advanced colorectal cancer? Final results of a five-arm study.
Author: Popov, Ivan|Jelic, Svetislav|Krivokapic, Zoran|Micev, Marjan|Babic, Dragana|Zdrale, Zdravko
PMID: 16340193
Journal: Cancer Res. 2006 Jul 1;66(13):6497-502.
Title: Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase.
Author: Gautam, Ashish|Bepler, Gerold
PMID: 16818620
Journal: Cancer. 2008 Jun 15;112(12):2765-73.
Title: Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer.
Author: Zheng, Zhong|Li, Xueli|Schell, Michael J|Chen, Tingan|Boulware, David|Robinson, Lary|Sommers, Eric|Bepler, Gerold
PMID: 18442042
Journal: Eur J Cancer. 2011 Apr;47(6):839-47.
Title: Association of RRM1 -37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy.
Author: Rodriguez, J|Boni, V|Hernandez, A|Bitarte, N|Zarate, R|Ponz-Sarvise, M|Chopitea, A|Bandres, E|Garcia-Foncillas, J
PMID: 21220199
Journal: Mol Cancer Res. 2012 Jun;10(6):787-99.
Title: SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.
Author: Matsushita, Kazuyuki|Kajiwara, Toshiko|Tamura, Mai|Satoh, Mamoru|Tanaka, Nobuko|Tomonaga, Takeshi|Matsubara, Hisahiro|Shimada, Hideaki|Yoshimoto, Rei|Ito, Akihiro|Kubo, Shuji|Natsume, Tohru|Levens, David|Yoshida, Minoru|Nomura, Fumio
PMID: 22496461
Journal: PLoS One. 2014 Nov 7;9(11):e112189.
Title: Expression profiling of rectal tumors defines response to neoadjuvant treatment related genes.
Author: Palma, Pablo|Cano, Carlos|Conde-Muino, Raquel|Comino, Ana|Bueno, Pablo|Ferron, J Antonio|Cuadros, Marta
PMID: 25380052
Journal: J Oncol Pharm Pract. 2014 Feb;20(1):11-28.
Title: Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation.
Author: Chung, Clement|Christianson, Matthew
PMID: 23493335
Journal: Exp Mol Pathol. 2015 Jun;98(3):375-81.
Title: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
Author: Wang, Huijuan|Yang, Bobo|Geng, Tingting|Li, Bin|Dai, Penggao|Chen, Chao
PMID: 25445497
Journal: Tumour Biol. 2015 Jun;36(6):4833-42.
Title: Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis.
Author: Qi, Hongyan|Lou, Meng|Chen, Yuexia|Liu, Xiyong|Chen, Naiming|Shan, Jianzhen|Ling, Zhiqiang|Shen, Jing|Zhu, Lijun|Yen, Yun|Zheng, Shu|Shao, Jimin
PMID: 25638032
Journal: Biomed Res Int. 2015;2015:968743.
Title: A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer.
Author: Savas, Sevtap|Xu, Jingxiong|Werdyani, Salem|Shestopaloff, Konstantin|Dicks, Elizabeth|Green, Jane|Parfrey, Patrick|Green, Roger|Xu, Wei
PMID: 26064972
Journal: Cancer Biol Ther. 2015;16(12):1726-37.
Title: Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
Author: El-Deiry, Wafik S|Vijayvergia, Namrata|Xiu, Joanne|Scicchitano, Angelique|Lim, Bora|Yee, Nelson S|Harvey, Harold A|Gatalica, Zoran|Reddy, Sandeep
PMID: 26553611
Journal: Cell Death Discov. 2016 May 9;2:16027.
Title: Repositioning of a cyclin-dependent kinase inhibitor GW8510 as a ribonucleotide reductase M2 inhibitor to treat human colorectal cancer.
Author: Hsieh, Y-Y|Chou, C-J|Lo, H-L|Yang, P-M
PMID: 27551518
Journal: J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author: Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K
PMID: 28280620
Journal: J Biol Chem. 2017 Jun 2;292(22):9136-9149.
Title: Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.
Author: Lou, Meng|Liu, Qian|Ren, Guoping|Zeng, Jiling|Xiang, Xueping|Ding, Yongfeng|Lin, Qinghui|Zhong, Tingting|Liu, Xia|Zhu, Lijun|Qi, Hongyan|Shen, Jing|Li, Haoran|Shao, Jimin
PMID: 28411237
Journal: Int J Mol Med. 2017 Nov;40(5):1457-1465.
Title: Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer.
Author: Toth, Csaba|Sukosd, Farkas|Valicsek, Erzsebet|Herpel, Esther|Schirmacher, Peter|Renner, Marcus|Mader, Christoph|Tiszlavicz, Laszlo|Kriegsmann, Jorg
PMID: 28949378
Journal: JMIR Res Protoc. 2018 Sep 25;7(9):e177.
Title: Monitoring Twitter Conversations for Targeted Recruitment in Cancer Trials in Los Angeles County: Protocol for a Mixed-Methods Pilot Study.
Author: Reuter, Katja|Angyan, Praveen|Le, NamQuyen|MacLennan, Alicia|Cole, Sarah|Bluthenthal, Ricky N|Lane, Christianne J|El-Khoueiry, Anthony B|Buchanan, Thomas A
PMID: 30274964