Primary Site >> Colorectal Cancer
Gene >> RRM1
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Ref: Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors. PMID: 15096505 |
Ref: In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant. PMID: 16230416 Ref: Expression microarray analysis and oligo array comparative genomic hybridization of acquired gemcitabine resistance in mouse colon reveals selection for chromosomal aberrations. PMID: 16288008 |
Ref: What is the best sequence of chemotherapy in advanced colorectal cancer? Final results of a five-arm study. PMID: 16340193 Ref: Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase. PMID: 16818620 |
Ref: Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer. PMID: 18442042 |
Ref: Association of RRM1 -37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy. PMID: 21220199 |
Ref: SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression. PMID: 22496461 |
Ref: Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation. PMID: 23493335 Ref: Expression profiling of rectal tumors defines response to neoadjuvant treatment related genes. PMID: 25380052 |
Ref: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR. PMID: 25445497 Ref: Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis. PMID: 25638032 Ref: A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer. PMID: 26064972 Ref: Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites. PMID: 26553611 |
Ref: Repositioning of a cyclin-dependent kinase inhibitor GW8510 as a ribonucleotide reductase M2 inhibitor to treat human colorectal cancer. PMID: 27551518 |
Ref: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. PMID: 28280620 Ref: Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. PMID: 28411237 Ref: Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer. PMID: 28949378 |
Ref: Monitoring Twitter Conversations for Targeted Recruitment in Cancer Trials in Los Angeles County: Protocol for a Mixed-Methods Pilot Study. PMID: 30274964 |