Primary Site >> Colorectal Cancer

Gene >> RPTOR

Journal: Anticancer Res. 2009 Aug;29(8):3185-90.
Title: Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.
Author: Johnson, Sara M|Gulhati, Pat|Arrieta, Isela|Wang, Xiaofu|Uchida, Tatsuo|Gao, Tianyan|Evers, B Mark
PMID: 19661333
Journal: Clin Cancer Res. 2009 Dec 1;15(23):7207-16.
Title: Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.
Author: Gulhati, Pat|Cai, Qingsong|Li, Jing|Liu, Jianyu|Rychahou, Piotr G|Qiu, Suimin|Lee, Eun Y|Silva, Scott R|Bowen, Kanika A|Gao, Tianyan|Evers, B Mark
PMID: 19934294
Journal: Biochem Biophys Res Commun. 2009 Sep 4;386(4):598-601.
Title: Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells.
Author: Wu, William Ka Kei|Volta, Viviana|Cho, Chi Hin|Wu, Ya Chun|Li, Hai Tao|Yu, Le|Li, Zhi Jie|Sung, Joseph Jao Yiu
PMID: 19540199
Journal: Gastroenterology. 2011 May;140(5):1556-63.e6.
Title: JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice.
Author: Fujishita, Teruaki|Aoki, Masahiro|Taketo, Makoto M
PMID: 21320501
Journal: Cancer Res. 2011 May 1;71(9):3246-56.
Title: mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Author: Gulhati, Pat|Bowen, Kanika A|Liu, Jianyu|Stevens, Payton D|Rychahou, Piotr G|Chen, Min|Lee, Eun Y|Weiss, Heidi L|O'Connor, Kathleen L|Gao, Tianyan|Evers, B Mark
PMID: 21430067
Journal: PLoS One. 2011;6(9):e24650.
Title: The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.
Author: White, James P|Baynes, John W|Welle, Stephen L|Kostek, Matthew C|Matesic, Lydia E|Sato, Shuichi|Carson, James A
PMID: 21949739
Journal: Biol Pharm Bull. 2011;34(10):1553-8.
Title: Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells.
Author: Khanal, Prem|Kang, Bong Seok|Yun, Hyo Jeong|Cho, Hae-Guk|Makarieva, Tatyana Nikolaevna|Choi, Hong Seok
PMID: 21963494
Journal: Cell Signal. 2013 Oct;25(10):1993-2002.
Title: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.
Author: Chen, Min-Bin|Zhang, Yan|Wei, Mu-Xin|Shen, Wei|Wu, Xiao-Yang|Yao, Chen|Lu, Pei-Hua
PMID: 23712032
Journal: Eur J Cancer. 2013 Oct;49(15):3311-9.
Title: Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression.
Author: Saxena, Ashish|Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
PMID: 23827854
Journal: Biochem Biophys Res Commun. 2014 Sep 5;451(4):587-91.
Title: PGE2-induced colon cancer growth is mediated by mTORC1.
Author: Dufour, Marc|Faes, Seraina|Dormond-Meuwly, Anne|Demartines, Nicolas|Dormond, Olivier
PMID: 25128827
Journal: Cancer Biol Ther. 2015;16(1):34-42.
Title: The preclinical evaluation of the dual mTORC1/2 inhibitor INK-128 as a potential anti-colorectal cancer agent.
Author: Li, Chen|Cui, Jian-Feng|Chen, Min-Bin|Liu, Chao-Ying|Liu, Feng|Zhang, Qian-De|Zou, Jian|Lu, Pei-Hua
PMID: 25692620
Journal: Oncotarget. 2015 Jun 10;6(16):13962-77.
Title: AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
Author: Mi, Wenting|Ye, Qing|Liu, Side|She, Qing-Bai
PMID: 25961827
Journal: Hum Pathol. 2015 Nov;46(11):1752-9.
Title: Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
Author: Shuhua, Wu|Chenbo, Sun|Yangyang, Li|Xiangqian, Gao|Shuang, He|Tangyue, Li|Dong, Tian
PMID: 26363527
Journal: Asian Pac J Cancer Prev. 2015;16(15):6549-56.
Title: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
Author: Wee, Lee Heng|Morad, Noor Azian|Aan, Goon Jo|Makpol, Suzana|Wan Ngah, Wan Zurinah|Mohd Yusof, Yasmin Anum
PMID: 26434873
Journal: J Clin Pathol. 2017 May;70(5):410-416.
Title: mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression.
Author: Sticz, Tamas|Molnar, Anna|Mark, Agnes|Hajdu, Melinda|Nagy, Noemi|Vegso, Gyula|Micsik, Tamas|Kopper, Laszlo|Sebestyen, Anna
PMID: 27729429
Journal: Oncotarget. 2017 Apr 4;8(14):23603-23612.
Title: The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.
Author: Zheng, Hua-Chuan|Liu, Jia-Jie|Li, Jing|Wu, Ji-Cheng|Yang, Lei|Zhao, Gui-Feng|Zhao, Xin|Jiang, Hua-Mao|Huang, Ke-Qiang|Li, Zhi-Jie
PMID: 28223542
Journal: J Nutr Biochem. 2018 Jul;57:276-286.
Title: Piperine potentiates curcumin-mediated repression of mTORC1 signaling in human intestinal epithelial cells: implications for the inhibition of protein synthesis and TNFalpha signaling.
Author: Kaur, Harleen|He, Bo|Zhang, Chenhua|Rodriguez, Elliott|Hage, David S|Moreau, Regis
PMID: 29800814
Journal: Pathol Oncol Res. 2018 Jun 7. pii: 10.1007/s12253-018-0434-4.
Title: The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells.
Author: Sticz, Tamas|Molnar, Anna|Danko, Titanilla|Hujber, Zoltan|Petovari, Gabor|Nagy, Noemi|Vegso, Gyula|Kopper, Laszlo|Sebestyen, Anna
PMID: 29882195
Journal: Zhonghua Bing Li Xue Za Zhi. 2018 Jul 8;47(7):492-498.
Title: [Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations].
Author: Yu, L|Liu, Z Y|Jiao, J|Shi, X L|Cui, W L|Zhang, W|Li, Q X
PMID: 29996312