Primary Site >> Colorectal Cancer
Gene >> RPTOR
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|
|
Ref: Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells. PMID: 19540199 Ref: Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. PMID: 19661333 Ref: Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. PMID: 19934294 |
Ref: JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice. PMID: 21320501 Ref: mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways. PMID: 21430067 Ref: The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse. PMID: 21949739 Ref: Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells. PMID: 21963494 |
Ref: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. PMID: 23712032 Ref: Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression. PMID: 23827854 |
Ref: PGE2-induced colon cancer growth is mediated by mTORC1. PMID: 25128827 |
Ref: The preclinical evaluation of the dual mTORC1/2 inhibitor INK-128 as a potential anti-colorectal cancer agent. PMID: 25692620 Ref: AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis. PMID: 25961827 Ref: Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma. PMID: 26363527 Ref: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways. PMID: 26434873 |
Ref: mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression. PMID: 27729429 Ref: The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target. PMID: 28223542 |
Ref: Piperine potentiates curcumin-mediated repression of mTORC1 signaling in human intestinal epithelial cells: implications for the inhibition of protein synthesis and TNFalpha signaling. PMID: 29800814 Ref: The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells. PMID: 29882195 Ref: [Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations]. PMID: 29996312 |