Primary Site >> Colorectal Cancer
Gene >> RPS6KB1
| 1. | |||||||||||
| Journal: | J Biol Chem. 2000 Dec 8;275(49):38261-7. | ||||||||||
| Title: | Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen. | ||||||||||
| Author: | Law, B K|Waltner-Law, M E|Entingh, A J|Chytil, A|Aakre, M E|Norgaard, P|Moses, H L | ||||||||||
| PMID: | 10993886 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2002 Aug 2;277(31):28127-34. Epub 2002 May 8. | ||||||||||
| Title: | Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture. | ||||||||||
| Author: | Zhang, Xiongwen|Shu, Lili|Hosoi, Hajime|Murti, K Gopal|Houghton, Peter J | ||||||||||
| PMID: | 12000755 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2004 Nov 5;279(45):47379-90. Epub 2004 Aug 10. | ||||||||||
| Title: | Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells. | ||||||||||
| Author: | Sawhney, Rajinder S|Cookson, Michelle M|Sharma, Bhavya|Hauser, Jennie|Brattain, Michael G | ||||||||||
| PMID: | 15304500 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Mol Med. 2006 Jan;17(1):69-75. | ||||||||||
| Title: | Expression of beta-catenin is regulated by PI-3 kinase and sodium butyrate in colorectal cancer cells. | ||||||||||
| Author: | Tureckova, Jolana|Kucerova, Dana|Vojtechova, Martina|Sloncova, Eva|Tuhackova, Zdena | ||||||||||
| PMID: | 16328013 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Lett. 2007 Jun 18;251(1):105-13. Epub 2006 Dec 18. | ||||||||||
| Title: | Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer. | ||||||||||
| Author: | Nozawa, Hiroaki|Watanabe, Toshiaki|Nagawa, Hirokazu | ||||||||||
| PMID: | 17175097 | ||||||||||
| 6. | |||||||||||
| Journal: | Virchows Arch. 2007 Mar;450(3):321-8. Epub 2007 Jan 30. | ||||||||||
| Title: | Co-expression of EGF receptor, TGFalpha and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosis. | ||||||||||
| Author: | Tampellini, Marco|Longo, Marina|Cappia, Susanna|Bacillo, Elisa|Alabiso, Irene|Volante, Marco|Dogliotti, Luigi|Papotti, Mauro | ||||||||||
| PMID: | 17265080 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2008 Apr 1;68(7):2384-90. | ||||||||||
| Title: | Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. | ||||||||||
| Author: | Zeng, Xuehuo|Kinsella, Timothy J | ||||||||||
| PMID: | 18381446 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Lett. 2011 Jul 28;306(2):151-60. | ||||||||||
| Title: | Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer. | ||||||||||
| Author: | Xu, Rui|Nakano, Kenji|Iwasaki, Hironori|Kumagai, Michiaki|Wakabayashi, Rie|Yamasaki, Akio|Suzuki, Hiroyuki|Mibu, Ryuichi|Onishi, Hideya|Katano, Mitsuo | ||||||||||
| PMID: | 21429662 | ||||||||||
| 9. | |||||||||||
| Journal: | Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1197-202. | ||||||||||
| Title: | Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro. | ||||||||||
| Author: | Bijnsdorp, I V|Peters, G J | ||||||||||
| PMID: | 22132975 | ||||||||||
| 10. | |||||||||||
| Journal: | Nutr Cancer. 2011 Nov;63(8):1226-34. | ||||||||||
| Title: | Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Caan, Bette J|Potter, John D|Wolff, Roger K | ||||||||||
| PMID: | 21999454 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Ther. 2011 Aug;10(8):1394-406. | ||||||||||
| Title: | Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. | ||||||||||
| Author: | Bhagwat, Shripad V|Gokhale, Prafulla C|Crew, Andrew P|Cooke, Andy|Yao, Yan|Mantis, Christine|Kahler, Jennifer|Workman, Jennifer|Bittner, Mark|Dudkin, Lorina|Epstein, David M|Gibson, Neil W|Wild, Robert|Arnold, Lee D|Houghton, Peter J|Pachter, Jonathan A | ||||||||||
| PMID: | 21673091 | ||||||||||
| 12. | |||||||||||
| Journal: | Mutat Res. 2011 Jan 10;706(1-2):13-20. | ||||||||||
| Title: | Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Wolff, Roger K | ||||||||||
| PMID: | 21035469 | ||||||||||
| 13. | |||||||||||
| Journal: | Gastroenterology. 2012 Jun;142(7):1504-15.e3. | ||||||||||
| Title: | Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. | ||||||||||
| Author: | Din, Farhat V N|Valanciute, Asta|Houde, Vanessa P|Zibrova, Daria|Green, Kevin A|Sakamoto, Kei|Alessi, Dario R|Dunlop, Malcolm G | ||||||||||
| PMID: | 22406476 | ||||||||||
| 14. | |||||||||||
| Journal: | Tumour Biol. 2013 Apr;34(2):683-93. | ||||||||||
| Title: | Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells. | ||||||||||
| Author: | Ding, Zhen-Yu|Liu, Gui-Hong|Olsson, Birgit|Sun, Xiao-Feng | ||||||||||
| PMID: | 23188704 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2013 Jul 23;8(7):e68817. | ||||||||||
| Title: | Genotype directed therapy in murine mismatch repair deficient tumors. | ||||||||||
| Author: | Kucherlapati, Melanie H|Esfahani, Shadi|Habibollahi, Peiman|Wang, Junning|Still, Eric R|Bronson, Roderick T|Mahmood, Umar|Kucherlapati, Raju S | ||||||||||
| PMID: | 23935891 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014. | ||||||||||
| Title: | Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Mullany, Lila E|Penney, Rosalind B|Wolff, Roger K | ||||||||||
| PMID: | 24959314 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2014 Jun 11;9(6):e99254. | ||||||||||
| Title: | Alpha-2-glycoprotein 1(AZGP1) regulates biological behaviors of LoVo cells by down-regulating mTOR signaling pathway and endogenous fatty acid synthesis. | ||||||||||
| Author: | Chang, Ligong|Tian, Xiaoqiang|Lu, Yinghui|Jia, Min|Wu, Peng|Huang, Peilin | ||||||||||
| PMID: | 24918753 | ||||||||||
| 18. | |||||||||||
| Journal: | Horm Metab Res. 2014 Feb;46(2):85-93. | ||||||||||
| Title: | Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells. | ||||||||||
| Author: | Baricevic, I|Roberts, D L|Renehan, A G | ||||||||||
| PMID: | 24068609 | ||||||||||
| 19. | |||||||||||
| Journal: | J Cell Sci. 2014 Feb 15;127(Pt 4):788-800. | ||||||||||
| Title: | Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation. | ||||||||||
| Author: | Cope, Claire L|Gilley, Rebecca|Balmanno, Kathryn|Sale, Matthew J|Howarth, Karen D|Hampson, Mark|Smith, Paul D|Guichard, Sylvie M|Cook, Simon J | ||||||||||
| PMID: | 24363449 | ||||||||||
| 20. | |||||||||||
| Journal: | J Cell Physiol. 2015 Sep;230(9):2281-98. | ||||||||||
| Title: | Nexavar/Stivarga and viagra interact to kill tumor cells. | ||||||||||
| Author: | Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul | ||||||||||
| PMID: | 25704960 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Biol Ther. 2015;16(5):733-42. | ||||||||||
| Title: | Differential regulation of autophagy and cell viability by ceramide species. | ||||||||||
| Author: | Cruickshanks, Nichola|Roberts, Jane L|Bareford, M Danielle|Tavallai, Mehrad|Poklepovic, Andrew|Booth, Laurence|Spiegel, Sarah|Dent, Paul | ||||||||||
| PMID: | 25803131 | ||||||||||
| 22. | |||||||||||
| Journal: | J Cell Biochem. 2016 Dec;117(12):2854-2863. | ||||||||||
| Title: | The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells. | ||||||||||
| Author: | Park, Yang-Seo|Liu, Ziyu|Vasamsetti, Bala Murali Krishna|Cho, Nam Jeong | ||||||||||
| PMID: | 27167250 | ||||||||||
| 23. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20. | ||||||||||
| Title: | mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity. | ||||||||||
| Author: | Jin, Zhe-Zhu|Wang, Wei|Fang, Di-Long|Jin, Yong-Jun | ||||||||||
| PMID: | 27565731 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncol Rep. 2017 Mar;37(3):1619-1626. | ||||||||||
| Title: | Inhibition of RAB1A suppresses epithelial-mesenchymal transition and proliferation of triple-negative breast cancer cells. | ||||||||||
| Author: | Xu, Hui|Qian, Mingping|Zhao, Bingkun|Wu, Chenyang|Maskey, Niraj|Song, Hongming|Li, Dengfeng|Song, Jialu|Hua, Kaiyao|Fang, Lin | ||||||||||
| PMID: | 28184936 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2017 Aug 3;8(51):88563-88574. | ||||||||||
| Title: | Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death. | ||||||||||
| Author: | Chen, Shun-Ting|Lee, Tzung-Yan|Tsai, Tung-Hu|Huang, Yu-Chuen|Lin, Yin-Cheng|Lin, Chin-Ping|Shieh, Hui-Ru|Hsu, Ming-Ling|Chi, Chih-Wen|Lee, Ming-Cheng|Chang, Hen-Hong|Chen, Yu-Jen | ||||||||||
| PMID: | 29179457 | ||||||||||
| 26. | |||||||||||
| Journal: | Molecules. 2017 Oct 3;22(10). pii: molecules22101657. | ||||||||||
| Title: | Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway. | ||||||||||
| Author: | Kapral, Malgorzata|Wawszczyk, Joanna|Jesse, Katarzyna|Paul-Samojedny, Monika|Kusmierz, Dariusz|Weglarz, Ludmila | ||||||||||
| PMID: | 28972559 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2017 Nov 2;36(44):6109-6118. | ||||||||||
| Title: | Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients. | ||||||||||
| Author: | Tsoi, H|Lam, K C|Dong, Y|Zhang, X|Lee, C K|Zhang, J|Ng, S C|Ng, S S M|Zheng, S|Chen, Y|Fang, J|Yu, J | ||||||||||
| PMID: | 28692053 | ||||||||||
| 28. | |||||||||||
| Journal: | Am J Cancer Res. 2017 Jun 1;7(6):1238-1251. eCollection 2017. | ||||||||||
| Title: | Identification of RING-box 2 as a potential target for combating colorectal cancer growth and metastasis. | ||||||||||
| Author: | Wu, Xiao-Yu|Fang, Jian|Wang, Zhao-Jin|Chen, Che|Liu, Jia-Yun|Wu, Guan-Nan|Yao, Xue-Quan|Liu, Fu-Kun|Zhou, Xin | ||||||||||
| PMID: | 28670488 | ||||||||||
| 29. | |||||||||||
| Journal: | Int J Med Sci. 2017 Jan 1;14(1):53-57. | ||||||||||
| Title: | Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival. | ||||||||||
| Author: | Yang, Ying-Pi|Ting, Wen-Chien|Chen, Lu-Min|Lu, Te-Ling|Bao, Bo-Ying | ||||||||||
| PMID: | 28138309 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 3;8(1):988-998. | ||||||||||
| Title: | Preclinical study of cinobufagin as a promising anti-colorectal cancer agent. | ||||||||||
| Author: | Lu, Xing-Sheng|Qiao, Yin-Biao|Li, Ya|Yang, Bo|Chen, Min-Bin|Xing, Chun-Gen | ||||||||||
| PMID: | 27894091 | ||||||||||
| 31. | |||||||||||
| Journal: | J Cell Sci. 2017 Jan 1;130(1):203-218. | ||||||||||
| Title: | Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. | ||||||||||
| Author: | Riedl, Angelika|Schlederer, Michaela|Pudelko, Karoline|Stadler, Mira|Walter, Stefanie|Unterleuthner, Daniela|Unger, Christine|Kramer, Nina|Hengstschlager, Markus|Kenner, Lukas|Pfeiffer, Dagmar|Krupitza, Georg|Dolznig, Helmut | ||||||||||
| PMID: | 27663511 | ||||||||||
| 32. | |||||||||||
| Journal: | Anticancer Res. 2018 Mar;38(3):1445-1454. | ||||||||||
| Title: | AZD8055 Exerts Antitumor Effects on Colon Cancer Cells by Inhibiting mTOR and Cell-cycle Progression. | ||||||||||
| Author: | Chen, Yun|Lee, Cheng-Hung|Tseng, Bor-Yuan|Tsai, Ya-Hui|Tsai, Huang-Wen|Yao, Chao-Ling|Tseng, Sheng-Hong | ||||||||||
| PMID: | 29491070 | ||||||||||
| 33. | |||||||||||
| Journal: | J Biol Chem. 2018 Sep 21;293(38):14891-14904. | ||||||||||
| Title: | Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. | ||||||||||
| Author: | Boyle, Kathleen A|Van Wickle, Jonathan|Hill, R Blake|Marchese, Adriano|Kalyanaraman, Balaraman|Dwinell, Michael B | ||||||||||
| PMID: | 30087121 | ||||||||||
| 34. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2018 Sep 18;503(4):3198-3204. | ||||||||||
| Title: | The influence of aberrant expression of GLI1/p-S6K on colorectal cancer. | ||||||||||
| Author: | Wang, Xuchao|Yao, Yizhou|Zhu, Xinguo | ||||||||||
| PMID: | 30143258 | ||||||||||
| 35. | |||||||||||
| Journal: | J Cell Physiol. 2018 Sep 10. | ||||||||||
| Title: | Neratinib augments the lethality of [regorafenib + sildenafil]. | ||||||||||
| Author: | Booth, Laurence|Roberts, Jane L|Rais, Rumeesa|Cutler, Richard E Jr|Diala, Irmina|Lalani, Alshad S|Hancock, John F|Poklepovic, Andrew|Dent, Paul | ||||||||||
| PMID: | 30203445 | ||||||||||
| 36. | |||||||||||
| Journal: | Gastroenterology. 2018 Oct 17. pii: S0016-5085(18)35161-8. | ||||||||||
| Title: | Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1. | ||||||||||
| Author: | Wang-Bishop, Lihong|Chen, Zheng|Gomaa, Ahmed|Lockhart, Albert Craig|Salaria, Safia|Wang, Jialiang|Lewis, Keeli B|Ecsedy, Jeffrey|Washington, Kay|Beauchamp, Robert Daniel|El-Rifai, Wael | ||||||||||
| PMID: | 30342037 | ||||||||||