Literatures

Primary Site >> Colorectal Cancer

Gene >> RNF43

1.
Journal:	Clin Cancer Res. 2004 Dec 15;10(24):8577-86.
Title:	Ring finger protein 43 as a new target for cancer immunotherapy.
Author:	Uchida, Naotaka\|Tsunoda, Takuya\|Wada, Satoshi\|Furukawa, Yoichi\|Nakamura, Yusuke\|Tahara, Hideaki
PMID:	15623641

2.
Journal:	Int J Oncol. 2004 Nov;25(5):1343-8.
Title:	A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Author:	Yagyu, Ryuichiro\|Furukawa, Yoichi\|Lin, Yu-Min\|Shimokawa, Takashi\|Yamamura, Takehira\|Nakamura, Yusuke
PMID:	15492824

3.
Journal:	Exp Cell Res. 2008 Apr 15;314(7):1519-28.
Title:	A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.
Author:	Sugiura, Takeyuki\|Yamaguchi, Aya\|Miyamoto, Kentaro
PMID:	18313049

4.
Journal:	Proteomics. 2008 Jul;8(14):2907-10.
Title:	Proteomic identification of a PSF/p54nrb heterodimer as RNF43 oncoprotein-interacting proteins.
Author:	Miyamoto, Kentaro\|Sakurai, Hidetaka\|Sugiura, Takeyuki
PMID:	18655028

5.
Journal:	Gan To Kagaku Ryoho. 2008 Nov;35(12):2268-70.
Title:	[Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
Author:	Yoshimatsu, Kazuhiko\|Yokomizo, Hajime\|Osawa, Gakuji\|Fujimoto, Takashi\|Otani, Taisuke\|Tsunoda, Takuya\|Nakamura, Yusuke\|Ogawa, Kenji
PMID:	19106592

6.
Journal:	Biochem Biophys Res Commun. 2011 Jan 7;404(1):143-7.
Title:	RNF43 interacts with NEDL1 and regulates p53-mediated transcription.
Author:	Shinada, Keisuke\|Tsukiyama, Tadasuke\|Sho, Takuya\|Okumura, Fumihiko\|Asaka, Masahiro\|Hatakeyama, Shigetsugu
PMID:	21108931

7.
Journal:	Tokai J Exp Clin Med. 2012 Jul 20;37(2):57-61.
Title:	Significant clinical response of advanced colon cancer to peptide vaccine therapy: a case report.
Author:	Yasuda, Seiei\|Tsuchiya, Izumi\|Okada, Kazutake\|Tanaka, Akira\|Suzuki, Toshiyuki\|Sadahiro, Sotaro\|Takeda, Kazuyoshi\|Yamamoto, Soichiro\|Nakui, Minoru
PMID:	22763829

8.
Journal:	Nature. 2012 Aug 30;488(7413):665-9.
Title:	Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Author:	Koo, Bon-Kyoung\|Spit, Maureen\|Jordens, Ingrid\|Low, Teck Y\|Stange, Daniel E\|van de Wetering, Marc\|van Es, Johan H\|Mohammed, Shabaz\|Heck, Albert J R\|Maurice, Madelon M\|Clevers, Hans
PMID:	22895187

9.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(12):1760-2.
Title:	[Clinical study of Peptide-cocktail vaccination with tegafur-uracil/leucovorin for advanced colorectal cancer].
Author:	Sugiura, Fumiaki\|Inoue, Keisuke\|Okuno, Kiyotaka\|Sukegawa, Yasushi
PMID:	23267878

10.
Journal:	Mol Cancer Ther. 2013 Jan;12(1):94-103.
Title:	Reversing effect of ring finger protein 43 inhibition on malignant phenotypes of human hepatocellular carcinoma.
Author:	Xing, Chunyang\|Zhou, Wuhua\|Ding, Songming\|Xie, Haiyang\|Zhang, Wu\|Yang, Zhe\|Wei, Bajin\|Chen, Kangjie\|Su, Rong\|Cheng, Jun\|Zheng, Shusen\|Zhou, Lin
PMID:	23136185

11.
Journal:	Mol Hum Reprod. 2013 Feb;19(2):57-71.
Title:	Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research.
Author:	Wang, K\|Li, N\|Yeung, C H\|Li, J Y\|Wang, H Y\|Cooper, T G
PMID:	23155044

12.
Journal:	Oncol Rep. 2013 Mar;29(3):951-9.
Title:	Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Author:	Matsushita, Norimasa\|Aruga, Atsushi\|Inoue, Yuji\|Kotera, Yoshihito\|Takeda, Kazuyoshi\|Yamamoto, Masakazu
PMID:	23314271

13.
Journal:	Gan To Kagaku Ryoho. 2013 Nov;40(12):1584-6.
Title:	[Treatment outcome of peptide vaccination for advanced colorectal cancer].
Author:	Sugiura, Fumiaki\|Inoue, Keisuke\|Kogita, Akihiro\|Yoshioka, Yasumasa\|Hida, Jinichi\|Okuno, Kiyotaka\|Sukegawa, Yasushi
PMID:	24393856

14.
Journal:	PLoS One. 2014 Jan 22;9(1):e86582.
Title:	Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
Author:	Takahashi, Norihiko\|Yamaguchi, Kiyoshi\|Ikenoue, Tsuneo\|Fujii, Tomoaki\|Furukawa, Yoichi
PMID:	24466159

15.
Journal:	Gan To Kagaku Ryoho. 2014 Oct;41(10):1276-9.
Title:	[Clinical trial of a seven-peptide vaccine and tegafur-uracil/leucovorin as combination therapy for advanced colorectal cancer].
Author:	Inoue, Keisuke\|Sugiura, Fumiaki\|Kogita, Akihiro\|Yoshioka, Yasumasa\|Sukegawa, Yasushi\|Hida, Jinichi\|Okuno, Kiyotaka
PMID:	25335716

16.
Journal:	J Transl Med. 2014 Mar 10;12:63.
Title:	A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Author:	Hazama, Shoichi\|Nakamura, Yusuke\|Takenouchi, Hiroko\|Suzuki, Nobuaki\|Tsunedomi, Ryouichi\|Inoue, Yuka\|Tokuhisa, Yoshihiro\|Iizuka, Norio\|Yoshino, Shigefumi\|Takeda, Kazuyoshi\|Shinozaki, Hirokazu\|Kamiya, Akira\|Furukawa, Hiroyuki\|Oka, Masaaki
PMID:	24612787

17.
Journal:	Nat Neurosci. 2014 Apr;17(4):506-12.
Title:	Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer.
Author:	Fancy, Stephen P J\|Harrington, Emily P\|Baranzini, Sergio E\|Silbereis, John C\|Shiow, Lawrence R\|Yuen, Tracy J\|Huang, Eric J\|Lomvardas, Stavros\|Rowitch, David H
PMID:	24609463

18.
Journal:	Genes Dev. 2014 Feb 15;28(4):305-16.
Title:	The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
Author:	de Lau, Wim\|Peng, Weng Chuan\|Gros, Piet\|Clevers, Hans
PMID:	24532711

19.
Journal:	Int J Clin Exp Pathol. 2015 Jan 1;8(1):490-6. eCollection 2015.
Title:	Downregulation of ring-finger protein 43 in glioma associates with poor prognosis.
Author:	Xi, Shaoyan\|Zhang, Xinke\|Chen, Huadong\|Zhong, Zhihai\|Lu, Jiabin\|Hu, Wanming\|Wu, Qiuliang\|Zeng, Jing
PMID:	25755738

20.
Journal:	Cell. 2015 May 7;161(4):933-45.
Title:	Prospective derivation of a living organoid biobank of colorectal cancer patients.
Author:	van de Wetering, Marc\|Francies, Hayley E\|Francis, Joshua M\|Bounova, Gergana\|Iorio, Francesco\|Pronk, Apollo\|van Houdt, Winan\|van Gorp, Joost\|Taylor-Weiner, Amaro\|Kester, Lennart\|McLaren-Douglas, Anne\|Blokker, Joyce\|Jaksani, Sridevi\|Bartfeld, Sina\|Volckman,
PMID:	25957691

21.
Journal:	Hum Pathol. 2015 Nov;46(11):1640-6.
Title:	Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers.
Author:	Jo, Yun Sol\|Kim, Min Sung\|Lee, Ju Hwa\|Lee, Sug Hyung\|An, Chang Hyeok\|Yoo, Nam Jin
PMID:	26297255

22.
Journal:	Sci Signal. 2015 Sep 8;8(393):ra90.
Title:	The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane.
Author:	Loregger, Anke\|Grandl, Martina\|Mejias-Luque, Raquel\|Allgauer, Michael\|Degenhart, Kathrin\|Haselmann, Verena\|Oikonomou, Christina\|Hatzis, Pantelis\|Janssen, Klaus-Peter\|Nitsche, Ulrich\|Gradl, Dietmar\|van den Broek, Olaf\|Destree, Olivier\|Ulm, Kurt\|Neumaier, M
PMID:	26350900

23.
Journal:	Cancer Biomark. 2015;15(6):789-97.
Title:	Clinicopathological significance and prognostic value of Wilms' tumor gene expression in colorectal cancer.
Author:	Miyata, Yukinaga\|Kumagai, Kenichi\|Nagaoka, Tomoko\|Kitaura, Kazutaka\|Kaneda, Goro\|Kanazawa, Hideki\|Suzuki, Satsuki\|Hamada, Yoshiki\|Suzuki, Ryuji
PMID:	26406403

24.
Journal:	Oncotarget. 2016 Oct 25;7(43):70589-70600.
Title:	RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.
Author:	Bond, Catherine E\|McKeone, Diane M\|Kalimutho, Murugan\|Bettington, Mark L\|Pearson, Sally-Ann\|Dumenil, Troy D\|Wockner, Leesa F\|Burge, Matthew\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	27661107

25.
Journal:	Am J Surg Pathol. 2016 Oct;40(10):1352-9.
Title:	RNF43 Is an Early and Specific Mutated Gene in the Serrated Pathway, With Increased Frequency in Traditional Serrated Adenoma and Its Associated Malignancy.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Tseng, Li-Hui\|Cheng, Mei-Ling\|Jeng, Yung-Ming
PMID:	27305845

26.
Journal:	BMC Cancer. 2016 Jul 26;16:539.
Title:	Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases.
Author:	Lee, Ja-Rang\|Kwon, Chae Hwa\|Choi, Yuri\|Park, Hye Ji\|Kim, Hyun Sung\|Jo, Hong-Jae\|Oh, Nahmgun\|Park, Do Youn
PMID:	27461012

27.
Journal:	Oncogene. 2016 Feb 4;35(5):651-61.
Title:	Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasis.
Author:	Wang, G\|Fu, Y\|Yang, X\|Luo, X\|Wang, J\|Gong, J\|Hu, J
PMID:	25961913

28.
Journal:	Cancer J. 2016 May-Jun;22(3):149-55.
Title:	Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.
Author:	Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	27341591

29.
Journal:	Sci Rep. 2017 Nov 10;7(1):15270.
Title:	RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Author:	Fischer, Marcus M\|Yeung, V Pete\|Cattaruzza, Fiore\|Hussein, Rajaa\|Yen, Wan-Ching\|Murriel, Christopher\|Evans, James W\|O'Young, Gilbert\|Brunner, Alayne L\|Wang, Min\|Cain, Jennifer\|Cancilla, Belinda\|Kapoun, Ann\|Hoey, Timothy
PMID:	29127379

30.
Journal:	J Natl Cancer Inst. 2017 Dec 1;109(12). pii: 3860155.
Title:	ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.
Author:	Pietrantonio, Filippo\|Di Nicolantonio, Federica\|Schrock, Alexa B\|Lee, Jeeyun\|Tejpar, Sabine\|Sartore-Bianchi, Andrea\|Hechtman, Jaclyn F\|Christiansen, Jason\|Novara, Luca\|Tebbutt, Niall\|Fuca, Giovanni\|Antoniotti, Carlotta\|Kim, Seung Tae\|Murphy, Danielle\|Bere
PMID:	29370427

31.
Journal:	Hered Cancer Clin Pract. 2017 Nov 29;15:22.
Title:	Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).
Author:	Horpaopan, Sukanya\|Kirfel, Jutta\|Peters, Sophia\|Kloth, Michael\|Huneburg, Robert\|Altmuller, Janine\|Drichel, Dmitriy\|Odenthal, Margarete\|Kristiansen, Glen\|Strassburg, Christian\|Nattermann, Jacob\|Hoffmann, Per\|Nurnberg, Peter\|Buttner, Reinhard\|Thiele, Holger
PMID:	29213343

32.
Journal:	Cancer Res. 2017 Dec 1;77(23):6562-6575.
Title:	DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer.
Author:	Huang, Shuo\|Fantini, Damiano\|Merrill, Bradley J\|Bagchi, Srilata\|Guzman, Grace\|Raychaudhuri, Pradip
PMID:	29021137

33.
Journal:	Oncogene. 2017 Oct 19;36(42):5915.
Title:	Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasis.
Author:	Wang, G\|Fu, Y\|Yang, X\|Luo, X\|Wang, J\|Gong, J\|Hu, J
PMID:	28846106

34.
Journal:	Oncol Lett. 2017 Aug;14(2):2281-2287.
Title:	RT-qPCR analysis of the tumor antigens TOMM34 and RNF43 in samples extracted from paraffin-embedded specimens of colorectal cancer.
Author:	Matsushita, Norimasa\|Yamamoto, Shiho\|Inoue, Yuji\|Aruga, Atsushi\|Yamamoto, Masakazu
PMID:	28789449

35.
Journal:	Int J Mol Med. 2017 Sep;40(3):587-606.
Title:	Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	28731148

36.
Journal:	Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title:	The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Mullany, Lila E\|Samowitz, Wade S\|Sevens, John R\|Sakoda, Lori\|Wolff, Roger K
PMID:	28675510

37.
Journal:	World J Gastrointest Oncol. 2017 Mar 15;9(3):105-120.
Title:	CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Author:	Sanchez-Vega, Francisco\|Gotea, Valer\|Chen, Yun-Ching\|Elnitski, Laura
PMID:	28344746

38.
Journal:	Cancer Sci. 2017 May;108(5):1013-1021.
Title:	Phase 1 study of OCV-C02, a peptide vaccine consisting of two peptide epitopes for refractory metastatic colorectal cancer.
Author:	Taniguchi, Hiroya\|Iwasa, Satoru\|Yamazaki, Kentaro\|Yoshino, Takayuki\|Kiryu, Chika\|Naka, Yoshiharu\|Liew, Ei Leen\|Sakata, Yuh
PMID:	28266765

39.
Journal:	Nat Med. 2017 Jan;23(1):60-68.
Title:	Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.
Author:	Steinhart, Zachary\|Pavlovic, Zvezdan\|Chandrashekhar, Megha\|Hart, Traver\|Wang, Xiaowei\|Zhang, Xiaoyu\|Robitaille, Melanie\|Brown, Kevin R\|Jaksani, Sridevi\|Overmeer, Rene\|Boj, Sylvia F\|Adams, Jarrett\|Pan, James\|Clevers, Hans\|Sidhu, Sachdev\|Moffat, Jason\|Anger
PMID:	27869803

40.
Journal:	Gut. 2017 Sep;66(9):1645-1656.
Title:	RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
Author:	Yan, Helen H N\|Lai, Jeffrey C W\|Ho, Siu Lun\|Leung, Wai Keung\|Law, Wai Lun\|Lee, Janet F Y\|Chan, Anthony K W\|Tsui, Wai Yin\|Chan, Annie S Y\|Lee, Bernard C H\|Yue, Sarah S K\|Man, Alice H Y\|Clevers, Hans\|Yuen, Siu Tsan\|Leung, Suet Yi
PMID:	27329244

41.
Journal:	Fam Cancer. 2018 Jan;17(1):63-69.
Title:	RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.
Author:	Fennell, Lochlan J\|Clendenning, Mark\|McKeone, Diane M\|Jamieson, Saara H\|Balachandran, Samanthy\|Borowsky, Jennifer\|Liu, John\|Kawamata, Futoshi\|Bond, Catherine E\|Rosty, Christophe\|Burge, Matthew E\|Buchanan, Daniel D\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	28573495

42.
Journal:	Cancer Cell. 2018 Jan 8;33(1):125-136.e3.
Title:	Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Author:	Yaeger, Rona\|Chatila, Walid K\|Lipsyc, Marla D\|Hechtman, Jaclyn F\|Cercek, Andrea\|Sanchez-Vega, Francisco\|Jayakumaran, Gowtham\|Middha, Sumit\|Zehir, Ahmet\|Donoghue, Mark T A\|You, Daoqi\|Viale, Agnes\|Kemeny, Nancy\|Segal, Neil H\|Stadler, Zsofia K\|Varghese, Anna
PMID:	29316426

43.
Journal:	Oncotarget. 2017 Dec 12;9(1):969-981.
Title:	Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling.
Author:	Fujita, Masashi\|Matsubara, Nagahide\|Matsuda, Ikuo\|Maejima, Kazuhiro\|Oosawa, Ayako\|Yamano, Tomoki\|Fujimoto, Akihiro\|Furuta, Mayuko\|Nakano, Kaoru\|Oku-Sasaki, Aya\|Tanaka, Hiroko\|Shiraishi, Yuichi\|Mateos, Raul Nicolas\|Nakai, Kenta\|Miyano, Satoru\|Tomita, Naohi
PMID:	29416670

44.
Journal:	Oncol Rep. 2018 May;39(5):2385-2392.
Title:	IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.
Author:	Kanekiyo, Shinsuke\|Hazama, Shoichi\|Takenouchi, Hiroko\|Nakajima, Masao\|Shindo, Yoshitaro\|Matsui, Hiroto\|Tokumitsu, Yukio\|Tomochika, Shinobu\|Tsunedomi, Ryouichi\|Tokuhisa, Yoshihiro\|Iida, Michihisa\|Sakamoto, Kazuhiko\|Suzuki, Nobuaki\|Takeda, Shigeru\|Yamamoto,
PMID:	29498403

45.
Journal:	J Pathol. 2018 Aug;245(4):445-455.
Title:	Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression.
Author:	Eto, Tsugio\|Miyake, Keisuke\|Nosho, Katsuhiko\|Ohmuraya, Masaki\|Imamura, Yu\|Arima, Kota\|Kanno, Shinichi\|Fu, Lingfeng\|Kiyozumi, Yuki\|Izumi, Daisuke\|Sugihara, Hidetaka\|Hiyoshi, Yukiharu\|Miyamoto, Yuji\|Sawayama, Hiroshi\|Iwatsuki, Masaaki\|Baba, Yoshifumi\|Yoshid
PMID:	29756208

46.
Journal:	Int J Mol Med. 2018 Aug;42(2):713-725.
Title:	Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author:	Katoh, Masaru
PMID:	29786110

47.
Journal:	Clin Cancer Res. 2018 Oct 1;24(19):4715-4725.
Title:	Clonal Structures of Regionally Synchronous Gastric Adenomas and Carcinomas.
Author:	Jung, Seung-Hyun\|Kim, Shin Young\|An, Chang Hyeok\|Lee, Sung Hak\|Jung, Eun Sun\|Park, Hyeon-Chun\|Kim, Min Sung\|Chung, Yeun-Jun\|Lee, Sug Hyung
PMID:	29945994

48.
Journal:	Stem Cell Reports. 2018 Aug 14;11(2):410-424.
Title:	The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells.
Author:	Strubberg, Ashlee M\|Veronese Paniagua, Daniel A\|Zhao, Tingting\|Dublin, Leeran\|Pritchard, Thomas\|Bayguinov, Peter O\|Fitzpatrick, James A J\|Madison, Blair B
PMID:	30017821

49.
Journal:	Carcinogenesis. 2018 Oct 31. pii: 5149556.
Title:	Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
Author:	Neumeyer, Victoria\|Grandl, Martina\|Dietl, Alisa\|Brutau-Abia, Anna\|Allgauer, Michael\|Kalali, Behnam\|Zhang, Yang\|Pan, Kai-Feng\|Steiger, Katja\|Vieth, Michael\|Anton, Martina\|Mejias-Luque, Raquel\|Gerhard, Markus
PMID:	30380024