Primary Site >> Pancreatic Cancer

Gene >> RHOA

Journal: Mol Cell Biol. 1998 Dec;18(12):6962-70.
Title: p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA.
Author: Adnane, J|Bizouarn, F A|Qian, Y|Hamilton, A D|Sebti, S M
PMID: 9819384
Journal: Br J Cancer. 1998;77(1):147-52.
Title: Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas.
Author: Suwa, H|Ohshio, G|Imamura, T|Watanabe, G|Arii, S|Imamura, M|Narumiya, S|Hiai, H|Fukumoto, M
PMID: 9459160
Journal: Cancer Res. 2001 Jun 15;61(12):4885-91.
Title: Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors.
Author: Kusama, T|Mukai, M|Iwasaki, T|Tatsuta, M|Matsumoto, Y|Akedo, H|Nakamura, H
PMID: 11406567
Journal: Gastroenterology. 2002 Feb;122(2):308-17.
Title: 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.
Author: Kusama, Toshiyuki|Mukai, Mutsuko|Iwasaki, Teruo|Tatsuta, Masaharu|Matsumoto, Yoshirou|Akedo, Hitoshi|Inoue, Masahiro|Nakamura, Hiroyuki
PMID: 11832446
Journal: J Cell Sci. 2003 Sep 15;116(Pt 18):3835-46. Epub 2003 Aug 5.
Title: Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.
Author: Stahle, Martina|Veit, Christine|Bachfischer, Ulla|Schierling, Karina|Skripczynski, Bettina|Hall, Alan|Gierschik, Peter|Giehl, Klaudia
PMID: 12902401
Journal: Clin Exp Metastasis. 2003;20(6):561-7.
Title: Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
Author: Kusama, Toshiyuki|Mukai, Mutsuko|Tatsuta, Masaharu|Matsumoto, Yoshirou|Nakamura, Hiroyuki|Inoue, Masahiro
PMID: 14598891
Journal: Cancer Res. 2004 Aug 1;64(15):5291-300.
Title: Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells.
Author: Veit, Christine|Genze, Felicitas|Menke, Andre|Hoeffert, Silke|Gress, Thomas M|Gierschik, Peter|Giehl, Klaudia
PMID: 15289335
Journal: Br J Cancer. 2005 Aug 8;93(3):319-30.
Title: Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.
Author: Bocci, G|Fioravanti, A|Orlandi, P|Bernardini, N|Collecchi, P|Del Tacca, M|Danesi, R
PMID: 16052215
Journal: Cell Signal. 2006 Aug;18(8):1156-68. Epub 2005 Oct 27.
Title: Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38.
Author: Dreissigacker, Ute|Mueller, Meike S|Unger, Monika|Siegert, Patrizia|Genze, Felicitas|Gierschik, Peter|Giehl, Klaudia
PMID: 16257181
Journal: Cancer Sci. 2006 Sep;97(9):848-53. Epub 2006 Jun 14.
Title: Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis.
Author: Kusama, Toshiyuki|Mukai, Mutsuko|Endo, Hiroko|Ishikawa, Osamu|Tatsuta, Masaharu|Nakamura, Hiroyuki|Inoue, Masahiro
PMID: 16776779
Journal: Int J Mol Med. 2007 Feb;19(2):273-8.
Title: STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17203201
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: Int J Oncol. 2007 May;30(5):1273-7.
Title: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17390031
Journal: Hum Pathol. 2008 Jul;39(7):1002-10.
Title: Prognostic significance of immunohistochemical RhoA expression on survival in pancreatic ductal adenocarcinoma: a high-throughput analysis.
Author: Dittert, Dag-Daniel|Kielisch, Christian|Alldinger, Ingo|Zietz, Christian|Meyer, Wolfdietrich|Dobrowolski, Frank|Saeger, Hans-Detlev|Baretton, Gustavo Bruno
PMID: 18495213
Journal: Int J Mol Med. 2009 Jun;23(6):763-9.
Title: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424602
Journal: Cancer Res. 2009 Oct 1;69(19):7851-9.
Title: TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation.
Author: Li, Zhongkui|Chang, Zhe|Chiao, Lucia J|Kang, Ya'an|Xia, Qianghua|Zhu, Cihui|Fleming, Jason B|Evans, Douglas B|Chiao, Paul J
PMID: 19773448
Journal: Biol Chem. 2009 Oct;390(10):1063-77.
Title: Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.
Author: Dietrich, Karin-Almut|Schwarz, Rene|Liska, Martina|Grass, Stefanie|Menke, Andre|Meister, Michael|Kierschke, Gesa|Langle, Claudia|Genze, Felicitas|Giehl, Klaudia
PMID: 19642867
Journal: Mol Cancer Ther. 2009 May;8(5):1218-26.
Title: In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I.
Author: Lu, Jie|Chan, Lai|Fiji, Hannah D G|Dahl, Russell|Kwon, Ohyun|Tamanoi, Fuyuhiko
PMID: 19417142
Journal: Carcinogenesis. 2009 Mar;30(3):457-65.
Title: LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.
Author: Komachi, Mayumi|Tomura, Hideaki|Malchinkhuu, Enkhzol|Tobo, Masayuki|Mogi, Chihiro|Yamada, Takayuki|Kimura, Takao|Kuwabara, Atsushi|Ohta, Hideo|Im, Doon-Soon|Kurose, Hitoshi|Takeyoshi, Izumi|Sato, Koichi|Okajima, Fumikazu
PMID: 19129242
Journal: Mol Cancer. 2010 Mar 17;9:61.
Title: RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones.
Author: Della Peruta, Marco|Giagulli, Cinzia|Laudanna, Carlo|Scarpa, Aldo|Sorio, Claudio
PMID: 20236512
Journal: Cancer Prev Res (Phila). 2010 Nov;3(11):1417-26.
Title: The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.
Author: Mohammed, Altaf|Janakiram, Naveena B|Li, Qian|Madka, Venkateshwar|Ely, Misty|Lightfoot, Stan|Crawford, Howard|Steele, Vernon E|Rao, Chinthalapally V
PMID: 21084261
Journal: Cancer Res. 2011 Feb 1;71(3):747-57.
Title: Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Author: Timpson, Paul|McGhee, Ewan J|Morton, Jennifer P|von Kriegsheim, Alex|Schwarz, Juliane P|Karim, Saadia A|Doyle, Brendan|Quinn, Jean A|Carragher, Neil O|Edward, Mike|Olson, Michael F|Frame, Margaret C|Brunton, Valerie G|Sansom, Owen J|Anderson, Kurt I
PMID: 21266354
Journal: Mol Cancer. 2011 Jul 3;10:79.
Title: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Author: Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kawaguchi, Junji|Hanamatsu, Toshimasa|Yoshioka, Takashi|Okano, Yukio|Hirose, Yoshinobu|Kozawa, Osamu|Moriwaki, Hisataka
PMID: 21722395
Journal: Int J Oncol. 2011 Nov;39(5):1243-52.
Title: BART inhibits pancreatic cancer cell invasion by inhibiting ARL2-mediated RhoA inactivation.
Author: Taniuchi, Keisuke|Iwasaki, Shinji|Saibara, Toshiji
PMID: 21833473
Journal: PLoS One. 2011;6(10):e26135.
Title: Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I.
Author: Chan, Lai N|Fiji, Hannah D G|Watanabe, Masaru|Kwon, Ohyun|Tamanoi, Fuyuhiko
PMID: 22028818
Journal: Mol Cancer. 2011 Nov 10;10:138.
Title: Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
Author: Vo, Kevin|Amarasinghe, Barushi|Washington, Kay|Gonzalez, Adriana|Berlin, Jordan|Dang, Thao P
PMID: 22074495
Journal: Int J Cancer. 2012 Oct 15;131(8):1951-62.
Title: Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
Author: Mohammed, Altaf|Qian, Li|Janakiram, Naveena B|Lightfoot, Stan|Steele, Vernon E|Rao, Chinthalapally V
PMID: 22287227
Journal: Cancer Lett. 2012 Sep 28;322(2):195-203.
Title: NOP14 promotes proliferation and metastasis of pancreatic cancer cells.
Author: Zhou, Bin|Wu, Qiao|Chen, Ge|Zhang, Tai-Ping|Zhao, Yu-Pei
PMID: 22425761
Journal: Tumour Biol. 2012 Dec;33(6):1863-70.
Title: miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.
Author: Hu, Yongjun|Ou, Yanglu|Wu, Kemin|Chen, Yuxiang|Sun, Weijia
PMID: 23070684
Journal: PLoS One. 2013 Dec 3;8(12):e81575.
Title: RhoC interacts with integrin alpha5beta1 and enhances its trafficking in migrating pancreatic carcinoma cells.
Author: Li, Ningfeng Fiona|Gemenetzidis, Emilios|Marshall, Francis J|Davies, Derek|Yu, Yongwei|Frese, Kristopher|Froeling, Fieke E M|Woolf, Adam K|Feakins, Roger M|Naito, Yoshiki|Iacobuzio-Donahue, Christine|Tuveson, David A|Hart, Ian R|Kocher, Hemant M
PMID: 24312560
Journal: BMC Cancer. 2013 Apr 22;13:198.
Title: In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells.
Author: Zimonjic, Drazen B|Chan, Lai N|Tripathi, Veenu|Lu, Jie|Kwon, Ohyun|Popescu, Nicholas C|Lowy, Douglas R|Tamanoi, Fuyuhiko
PMID: 23607551
Journal: Mol Cancer Res. 2013 Mar;11(3):230-9.
Title: Balanced Tiam1-rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells.
Author: Guo, Xingjun|Wang, Min|Jiang, Jianxin|Xie, Chengchen|Peng, Feng|Li, Xu|Tian, Rui|Qin, Renyi
PMID: 23322732
Journal: J Sci Food Agric. 2013 Apr;93(6):1492-8.
Title: Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway.
Author: Wang, Jieqiong|Liu, Yali|Zhao, Jingjing|Zhang, Wen|Pang, Xiufeng
PMID: 23450726
Journal: FEBS Lett. 2014 Aug 25;588(17):3240-50.
Title: Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
Author: Fujita, Mayumi|Imadome, Kaori|Endo, Satoshi|Shoji, Yoshimi|Yamada, Shigeru|Imai, Takashi
PMID: 25019574
Journal: Mol Carcinog. 2015 Mar;54(3):203-15.
Title: Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.
Author: Zimmerman, Noah P|Roy, Ishan|Hauser, Andrew D|Wilson, Jessica M|Williams, Carol L|Dwinell, Michael B
PMID: 24115212
Journal: Mol Cell Biochem. 2015 Jan;398(1-2):55-62.
Title: GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK.
Author: Yuan, X P|Dong, Ming|Li, Xin|Zhou, J P
PMID: 25218495
Journal: Cancer Lett. 2015 Mar 28;358(2):161-169.
Title: Salinomycin inhibits growth of pancreatic cancer and cancer cell migration by disruption of actin stress fiber integrity.
Author: Schenk, Miriam|Aykut, Berk|Teske, Christian|Giese, Nathalia A|Weitz, Juergen|Welsch, Thilo
PMID: 25529011
Journal: Int J Biol Markers. 2015 May 26;30(2):e226-33.
Title: Identification of biomarkers for the prognosis of pancreatic ductal adenocarcinoma with miRNA microarray data.
Author: Wang, Song|Zhao, Yanxun|Li, Dongsheng|Zhu, Liangchen|Shen, Zugang
PMID: 25791160
Journal: BMC Cancer. 2015 Apr 11;15:266.
Title: The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion.
Author: Pasiliao, Clarissa C|Chang, Che-Wei A|Sutherland, Brent W|Valdez, Shannon M|Schaeffer, David|Yapp, Donald T|Ng, Sylvia S W
PMID: 25886367
Journal: Int J Radiat Oncol Biol Phys. 2015 Sep 1;93(1):173-80.
Title: Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation.
Author: Fujita, Mayumi|Imadome, Kaori|Shoji, Yoshimi|Isozaki, Tetsurou|Endo, Satoshi|Yamada, Shigeru|Imai, Takashi
PMID: 26279033
Journal: Cancer Growth Metastasis. 2015 Oct 19;8(Suppl 1):95-113.
Title: Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways.
Author: Padavano, Julianna|Henkhaus, Rebecca S|Chen, Hwudaurw|Skovan, Bethany A|Cui, Haiyan|Ignatenko, Natalia A
PMID: 26512205
Journal: Sci Rep. 2015 Nov 4;5:16067.
Title: Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
Author: Niu, Zheyu|Wang, Mengyi|Zhou, Li|Yao, Lutian|Liao, Quan|Zhao, Yupei
PMID: 26530532
Journal: Mol Cell Biol. 2016 Sep 26;36(20):2596-611.
Title: Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
Author: Li, Chunhui|MacDonald, James I S|Talebian, Asghar|Leuenberger, Jennifer|Seah, Claudia|Pasternak, Stephen H|Michnick, Stephen W|Meakin, Susan O
PMID: 27503856
Journal: Oncol Lett. 2016 Dec;12(6):4677-4684.
Title: Analysis of transcription profile to reveal altered signaling pathways following the overexpression of human desumoylating isopeptidase 2 in pancreatic cancer cells.
Author: Fu, Yu-Yin|Kang, Yu-Huan|Shen, Cong-Cong|Wang, Rui-Xue|Yu, Lin|Li, Xin-Yue|Cui, Dan-Dan|Yang, Jin-Liang|Yao, Yu-Qin|Gou, Lan-Tu
PMID: 28105175
Journal: Sci Data. 2016 Nov 8;3:160101.
Title: ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells.
Author: Rath, Nicola|Kalna, Gabriela|Clark, William|Olson, Michael F
PMID: 27824338
Journal: Mol Cancer. 2016 May 4;15(1):32.
Title: ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells.
Author: Fukushima, Hiroto|Yasumoto, Makiko|Ogasawara, Sachiko|Akiba, Jun|Kitasato, Yuhei|Nakayama, Masamichi|Naito, Yoshiki|Ishida, Yusuke|Okabe, Yoshinobu|Yasunaga, Masafumi|Horiuchi, Hiroyuki|Sakamoto, Etsuko|Itadani, Hiraku|Mizuarai, Shinji|Oie, Shinji|Yano, H
PMID: 27145964
Journal: Mol Cancer Res. 2016 Mar;14(3):267-77.
Title: Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1.
Author: Kent, Oliver A|Mendell, Joshua T|Rottapel, Robert
PMID: 26747707
Journal: Biochem Pharmacol. 2016 Feb 15;102:107-119.
Title: Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells.
Author: Rivera, Io-Guane|Ordonez, Marta|Presa, Natalia|Gangoiti, Patricia|Gomez-Larrauri, Ana|Trueba, Miguel|Fox, Todd|Kester, Mark|Gomez-Munoz, Antonio
PMID: 26707801
Journal: Biol Pharm Bull. 2016 Aug 1;39(8):1238-46.
Title: Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study.
Author: Elsayed, Mahitab|Kobayashi, Daisuke|Kubota, Toshio|Matsunaga, Naoya|Murata, Ryusei|Yoshizawa, Yuko|Watanabe, Natsuki|Matsuura, Tohru|Tsurudome, Yuya|Ogino, Takashi|Ohdo, Shigehiro|Shimazoe, Takao
PMID: 27181081
Journal: Cell Death Dis. 2017 May 18;8(5):e2806.
Title: ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca(2+)/RhoA pathway.
Author: Zhu, Shuai|Zhou, Hai-Yun|Deng, Shi-Chang|Deng, Shi-Jiang|He, Chi|Li, Xiang|Chen, Jing-Yuan|Jin, Yan|Hu, Zhuang-Li|Wang, Fang|Wang, Chun-You|Zhao, Gang
PMID: 28518134
Journal: Mol Cancer. 2017 Nov 9;16(1):169.
Title: Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer.
Author: Li, Hongzhe|Wang, Xinjing|Wen, Chenlei|Huo, Zhen|Wang, Weishen|Zhan, Qian|Cheng, Dongfeng|Chen, Hao|Deng, Xiaxing|Peng, Chenghong|Shen, Baiyong
PMID: 29121972
Journal: Cell Rep. 2017 Oct 3;21(1):274-288.
Title: A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
Author: Nobis, Max|Herrmann, David|Warren, Sean C|Kadir, Shereen|Leung, Wilfred|Killen, Monica|Magenau, Astrid|Stevenson, David|Lucas, Morghan C|Reischmann, Nadine|Vennin, Claire|Conway, James R W|Boulghourjian, Alice|Zaratzian, Anaiis|Law, Andrew M|Gallego-Orteg
PMID: 28978480
Journal: Int J Oncol. 2017 Jul;51(1):184-192.
Title: Crizotinib, a MET inhibitor, prevents peritoneal dissemination in pancreatic cancer.
Author: Takiguchi, Soichi|Inoue, Kazuko|Matsusue, Kimihiko|Furukawa, Masayuki|Teramoto, Norihiro|Iguchi, Haruo
PMID: 28498406
Journal: Oncotarget. 2017 May 23;8(21):34586-34600.
Title: Discovery and characterization of small molecule Rac1 inhibitors.
Author: Arnst, Jamie L|Hein, Ashley L|Taylor, Margaret A|Palermo, Nick Y|Contreras, Jacob I|Sonawane, Yogesh A|Wahl, Andrew O|Ouellette, Michel M|Natarajan, Amarnath|Yan, Ying
PMID: 28410221
Journal: Neoplasma. 2017;64(1):32-39.
Title: Expression of orphan GPR56 correlates with tumor progression in human epithelial ovarian cancer.
Author: Liu, Z|Huang, Z|Yang, W|Li, Z|Xing, S|Li, H|Hu, B|Li, P
PMID: 27881002
Journal: Oncotarget. 2017 Jan 17;8(3):4484-4500.
Title: An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.
Author: Kent, Oliver A|Sandi, Maria-Jose|Burston, Helen E|Brown, Kevin R|Rottapel, Robert
PMID: 27835861
Journal: Neuro Oncol. 2018 Jan 22;20(2):192-202.
Title: Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Author: Olmez, Inan|Love, Shawn|Xiao, Aizhen|Manigat, Laryssa|Randolph, Peyton|McKenna, Brian D|Neal, Brian P|Boroda, Salome|Li, Ming|Brenneman, Breanna|Abounader, Roger|Floyd, Desiree|Lee, Jeongwu|Nakano, Ichiro|Godlewski, Jakub|Bronisz, Agnieszka|Sulman, Erik P
PMID: 29048560
Journal: Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1537-1546.
Title: Transforming growth factor-beta modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion.
Author: Stylianou, Andreas|Gkretsi, Vasiliki|Stylianopoulos, Triantafyllos
PMID: 29477748
Journal: J Am Chem Soc. 2018 Apr 4;140(13):4473-4476.
Title: Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids.
Author: Gebregiworgis, Teklab|Marshall, Christopher B|Nishikawa, Tadateru|Radulovich, Nikolina|Sandi, Maria-Jose|Fang, Zhenhao|Rottapel, Robert|Tsao, Ming-Sound|Ikura, Mitsuhiko
PMID: 29543440
Journal: Exp Mol Med. 2018 May 1;50(5):59.
Title: Gastrin stimulates pancreatic cancer cell directional migration by activating the Galpha12/13-RhoA-ROCK signaling pathway.
Author: Mu, Ganggang|Ding, Qianshan|Li, Hongyan|Zhang, Li|Zhang, Lingli|He, Ke|Wu, Lu|Deng, Yunchao|Yang, Dongmei|Wu, Lianlian|Xu, Ming|Zhou, Jie|Yu, Honggang
PMID: 29717112
Journal: NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title: Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author: Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling
PMID: 29872721
Journal: J Exp Clin Cancer Res. 2018 Jul 31;37(1):177.
Title: Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis.
Author: Li, Jie|Li, Zhonghu|Jiang, Peng|Peng, Minjie|Zhang, Xi|Chen, Kai|Liu, Hui|Bi, Huaqiang|Liu, Xiangde|Li, Xiaowu
PMID: 30064461