Primary Site >> Pancreatic Cancer
Gene >> RHOA
| 1. | |||||||||||
| Journal: | Mol Cell Biol. 1998 Dec;18(12):6962-70. | ||||||||||
| Title: | p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA. | ||||||||||
| Author: | Adnane, J|Bizouarn, F A|Qian, Y|Hamilton, A D|Sebti, S M | ||||||||||
| PMID: | 9819384 | ||||||||||
| 2. | |||||||||||
| Journal: | Br J Cancer. 1998;77(1):147-52. | ||||||||||
| Title: | Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. | ||||||||||
| Author: | Suwa, H|Ohshio, G|Imamura, T|Watanabe, G|Arii, S|Imamura, M|Narumiya, S|Hiai, H|Fukumoto, M | ||||||||||
| PMID: | 9459160 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2001 Jun 15;61(12):4885-91. | ||||||||||
| Title: | Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. | ||||||||||
| Author: | Kusama, T|Mukai, M|Iwasaki, T|Tatsuta, M|Matsumoto, Y|Akedo, H|Nakamura, H | ||||||||||
| PMID: | 11406567 | ||||||||||
| 4. | |||||||||||
| Journal: | Gastroenterology. 2002 Feb;122(2):308-17. | ||||||||||
| Title: | 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. | ||||||||||
| Author: | Kusama, Toshiyuki|Mukai, Mutsuko|Iwasaki, Teruo|Tatsuta, Masaharu|Matsumoto, Yoshirou|Akedo, Hitoshi|Inoue, Masahiro|Nakamura, Hiroyuki | ||||||||||
| PMID: | 11832446 | ||||||||||
| 5. | |||||||||||
| Journal: | J Cell Sci. 2003 Sep 15;116(Pt 18):3835-46. Epub 2003 Aug 5. | ||||||||||
| Title: | Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. | ||||||||||
| Author: | Stahle, Martina|Veit, Christine|Bachfischer, Ulla|Schierling, Karina|Skripczynski, Bettina|Hall, Alan|Gierschik, Peter|Giehl, Klaudia | ||||||||||
| PMID: | 12902401 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Exp Metastasis. 2003;20(6):561-7. | ||||||||||
| Title: | Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor. | ||||||||||
| Author: | Kusama, Toshiyuki|Mukai, Mutsuko|Tatsuta, Masaharu|Matsumoto, Yoshirou|Nakamura, Hiroyuki|Inoue, Masahiro | ||||||||||
| PMID: | 14598891 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2004 Aug 1;64(15):5291-300. | ||||||||||
| Title: | Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells. | ||||||||||
| Author: | Veit, Christine|Genze, Felicitas|Menke, Andre|Hoeffert, Silke|Gress, Thomas M|Gierschik, Peter|Giehl, Klaudia | ||||||||||
| PMID: | 15289335 | ||||||||||
| 8. | |||||||||||
| Journal: | Br J Cancer. 2005 Aug 8;93(3):319-30. | ||||||||||
| Title: | Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. | ||||||||||
| Author: | Bocci, G|Fioravanti, A|Orlandi, P|Bernardini, N|Collecchi, P|Del Tacca, M|Danesi, R | ||||||||||
| PMID: | 16052215 | ||||||||||
| 9. | |||||||||||
| Journal: | Cell Signal. 2006 Aug;18(8):1156-68. Epub 2005 Oct 27. | ||||||||||
| Title: | Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38. | ||||||||||
| Author: | Dreissigacker, Ute|Mueller, Meike S|Unger, Monika|Siegert, Patrizia|Genze, Felicitas|Gierschik, Peter|Giehl, Klaudia | ||||||||||
| PMID: | 16257181 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Sci. 2006 Sep;97(9):848-53. Epub 2006 Jun 14. | ||||||||||
| Title: | Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis. | ||||||||||
| Author: | Kusama, Toshiyuki|Mukai, Mutsuko|Endo, Hiroko|Ishikawa, Osamu|Tatsuta, Masaharu|Nakamura, Hiroyuki|Inoue, Masahiro | ||||||||||
| PMID: | 16776779 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Mol Med. 2007 Feb;19(2):273-8. | ||||||||||
| Title: | STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review). | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 17203201 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Mol Med. 2007 Mar;19(3):529-33. | ||||||||||
| Title: | Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 17273804 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Oncol. 2007 May;30(5):1273-7. | ||||||||||
| Title: | Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 17390031 | ||||||||||
| 14. | |||||||||||
| Journal: | Hum Pathol. 2008 Jul;39(7):1002-10. | ||||||||||
| Title: | Prognostic significance of immunohistochemical RhoA expression on survival in pancreatic ductal adenocarcinoma: a high-throughput analysis. | ||||||||||
| Author: | Dittert, Dag-Daniel|Kielisch, Christian|Alldinger, Ingo|Zietz, Christian|Meyer, Wolfdietrich|Dobrowolski, Frank|Saeger, Hans-Detlev|Baretton, Gustavo Bruno | ||||||||||
| PMID: | 18495213 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Mol Med. 2009 Jun;23(6):763-9. | ||||||||||
| Title: | Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 19424602 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Res. 2009 Oct 1;69(19):7851-9. | ||||||||||
| Title: | TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation. | ||||||||||
| Author: | Li, Zhongkui|Chang, Zhe|Chiao, Lucia J|Kang, Ya'an|Xia, Qianghua|Zhu, Cihui|Fleming, Jason B|Evans, Douglas B|Chiao, Paul J | ||||||||||
| PMID: | 19773448 | ||||||||||
| 17. | |||||||||||
| Journal: | Biol Chem. 2009 Oct;390(10):1063-77. | ||||||||||
| Title: | Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity. | ||||||||||
| Author: | Dietrich, Karin-Almut|Schwarz, Rene|Liska, Martina|Grass, Stefanie|Menke, Andre|Meister, Michael|Kierschke, Gesa|Langle, Claudia|Genze, Felicitas|Giehl, Klaudia | ||||||||||
| PMID: | 19642867 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 May;8(5):1218-26. | ||||||||||
| Title: | In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I. | ||||||||||
| Author: | Lu, Jie|Chan, Lai|Fiji, Hannah D G|Dahl, Russell|Kwon, Ohyun|Tamanoi, Fuyuhiko | ||||||||||
| PMID: | 19417142 | ||||||||||
| 19. | |||||||||||
| Journal: | Carcinogenesis. 2009 Mar;30(3):457-65. | ||||||||||
| Title: | LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites. | ||||||||||
| Author: | Komachi, Mayumi|Tomura, Hideaki|Malchinkhuu, Enkhzol|Tobo, Masayuki|Mogi, Chihiro|Yamada, Takayuki|Kimura, Takao|Kuwabara, Atsushi|Ohta, Hideo|Im, Doon-Soon|Kurose, Hitoshi|Takeyoshi, Izumi|Sato, Koichi|Okajima, Fumikazu | ||||||||||
| PMID: | 19129242 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Cancer. 2010 Mar 17;9:61. | ||||||||||
| Title: | RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones. | ||||||||||
| Author: | Della Peruta, Marco|Giagulli, Cinzia|Laudanna, Carlo|Scarpa, Aldo|Sorio, Claudio | ||||||||||
| PMID: | 20236512 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2010 Nov;3(11):1417-26. | ||||||||||
| Title: | The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model. | ||||||||||
| Author: | Mohammed, Altaf|Janakiram, Naveena B|Li, Qian|Madka, Venkateshwar|Ely, Misty|Lightfoot, Stan|Crawford, Howard|Steele, Vernon E|Rao, Chinthalapally V | ||||||||||
| PMID: | 21084261 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2011 Feb 1;71(3):747-57. | ||||||||||
| Title: | Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. | ||||||||||
| Author: | Timpson, Paul|McGhee, Ewan J|Morton, Jennifer P|von Kriegsheim, Alex|Schwarz, Juliane P|Karim, Saadia A|Doyle, Brendan|Quinn, Jean A|Carragher, Neil O|Edward, Mike|Olson, Michael F|Frame, Margaret C|Brunton, Valerie G|Sansom, Owen J|Anderson, Kurt I | ||||||||||
| PMID: | 21266354 | ||||||||||
| 23. | |||||||||||
| Journal: | Mol Cancer. 2011 Jul 3;10:79. | ||||||||||
| Title: | Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells. | ||||||||||
| Author: | Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kawaguchi, Junji|Hanamatsu, Toshimasa|Yoshioka, Takashi|Okano, Yukio|Hirose, Yoshinobu|Kozawa, Osamu|Moriwaki, Hisataka | ||||||||||
| PMID: | 21722395 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Oncol. 2011 Nov;39(5):1243-52. | ||||||||||
| Title: | BART inhibits pancreatic cancer cell invasion by inhibiting ARL2-mediated RhoA inactivation. | ||||||||||
| Author: | Taniuchi, Keisuke|Iwasaki, Shinji|Saibara, Toshiji | ||||||||||
| PMID: | 21833473 | ||||||||||
| 25. | |||||||||||
| Journal: | PLoS One. 2011;6(10):e26135. | ||||||||||
| Title: | Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I. | ||||||||||
| Author: | Chan, Lai N|Fiji, Hannah D G|Watanabe, Masaru|Kwon, Ohyun|Tamanoi, Fuyuhiko | ||||||||||
| PMID: | 22028818 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cancer. 2011 Nov 10;10:138. | ||||||||||
| Title: | Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation. | ||||||||||
| Author: | Vo, Kevin|Amarasinghe, Barushi|Washington, Kay|Gonzalez, Adriana|Berlin, Jordan|Dang, Thao P | ||||||||||
| PMID: | 22074495 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2012 Oct 15;131(8):1951-62. | ||||||||||
| Title: | Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice. | ||||||||||
| Author: | Mohammed, Altaf|Qian, Li|Janakiram, Naveena B|Lightfoot, Stan|Steele, Vernon E|Rao, Chinthalapally V | ||||||||||
| PMID: | 22287227 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Lett. 2012 Sep 28;322(2):195-203. | ||||||||||
| Title: | NOP14 promotes proliferation and metastasis of pancreatic cancer cells. | ||||||||||
| Author: | Zhou, Bin|Wu, Qiao|Chen, Ge|Zhang, Tai-Ping|Zhao, Yu-Pei | ||||||||||
| PMID: | 22425761 | ||||||||||
| 29. | |||||||||||
| Journal: | Tumour Biol. 2012 Dec;33(6):1863-70. | ||||||||||
| Title: | miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. | ||||||||||
| Author: | Hu, Yongjun|Ou, Yanglu|Wu, Kemin|Chen, Yuxiang|Sun, Weijia | ||||||||||
| PMID: | 23070684 | ||||||||||
| 30. | |||||||||||
| Journal: | PLoS One. 2013 Dec 3;8(12):e81575. | ||||||||||
| Title: | RhoC interacts with integrin alpha5beta1 and enhances its trafficking in migrating pancreatic carcinoma cells. | ||||||||||
| Author: | Li, Ningfeng Fiona|Gemenetzidis, Emilios|Marshall, Francis J|Davies, Derek|Yu, Yongwei|Frese, Kristopher|Froeling, Fieke E M|Woolf, Adam K|Feakins, Roger M|Naito, Yoshiki|Iacobuzio-Donahue, Christine|Tuveson, David A|Hart, Ian R|Kocher, Hemant M | ||||||||||
| PMID: | 24312560 | ||||||||||
| 31. | |||||||||||
| Journal: | BMC Cancer. 2013 Apr 22;13:198. | ||||||||||
| Title: | In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells. | ||||||||||
| Author: | Zimonjic, Drazen B|Chan, Lai N|Tripathi, Veenu|Lu, Jie|Kwon, Ohyun|Popescu, Nicholas C|Lowy, Douglas R|Tamanoi, Fuyuhiko | ||||||||||
| PMID: | 23607551 | ||||||||||
| 32. | |||||||||||
| Journal: | Mol Cancer Res. 2013 Mar;11(3):230-9. | ||||||||||
| Title: | Balanced Tiam1-rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells. | ||||||||||
| Author: | Guo, Xingjun|Wang, Min|Jiang, Jianxin|Xie, Chengchen|Peng, Feng|Li, Xu|Tian, Rui|Qin, Renyi | ||||||||||
| PMID: | 23322732 | ||||||||||
| 33. | |||||||||||
| Journal: | J Sci Food Agric. 2013 Apr;93(6):1492-8. | ||||||||||
| Title: | Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway. | ||||||||||
| Author: | Wang, Jieqiong|Liu, Yali|Zhao, Jingjing|Zhang, Wen|Pang, Xiufeng | ||||||||||
| PMID: | 23450726 | ||||||||||
| 34. | |||||||||||
| Journal: | FEBS Lett. 2014 Aug 25;588(17):3240-50. | ||||||||||
| Title: | Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation. | ||||||||||
| Author: | Fujita, Mayumi|Imadome, Kaori|Endo, Satoshi|Shoji, Yoshimi|Yamada, Shigeru|Imai, Takashi | ||||||||||
| PMID: | 25019574 | ||||||||||
| 35. | |||||||||||
| Journal: | Mol Carcinog. 2015 Mar;54(3):203-15. | ||||||||||
| Title: | Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells. | ||||||||||
| Author: | Zimmerman, Noah P|Roy, Ishan|Hauser, Andrew D|Wilson, Jessica M|Williams, Carol L|Dwinell, Michael B | ||||||||||
| PMID: | 24115212 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Cell Biochem. 2015 Jan;398(1-2):55-62. | ||||||||||
| Title: | GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK. | ||||||||||
| Author: | Yuan, X P|Dong, Ming|Li, Xin|Zhou, J P | ||||||||||
| PMID: | 25218495 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Lett. 2015 Mar 28;358(2):161-169. | ||||||||||
| Title: | Salinomycin inhibits growth of pancreatic cancer and cancer cell migration by disruption of actin stress fiber integrity. | ||||||||||
| Author: | Schenk, Miriam|Aykut, Berk|Teske, Christian|Giese, Nathalia A|Weitz, Juergen|Welsch, Thilo | ||||||||||
| PMID: | 25529011 | ||||||||||
| 38. | |||||||||||
| Journal: | Int J Biol Markers. 2015 May 26;30(2):e226-33. | ||||||||||
| Title: | Identification of biomarkers for the prognosis of pancreatic ductal adenocarcinoma with miRNA microarray data. | ||||||||||
| Author: | Wang, Song|Zhao, Yanxun|Li, Dongsheng|Zhu, Liangchen|Shen, Zugang | ||||||||||
| PMID: | 25791160 | ||||||||||
| 39. | |||||||||||
| Journal: | BMC Cancer. 2015 Apr 11;15:266. | ||||||||||
| Title: | The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion. | ||||||||||
| Author: | Pasiliao, Clarissa C|Chang, Che-Wei A|Sutherland, Brent W|Valdez, Shannon M|Schaeffer, David|Yapp, Donald T|Ng, Sylvia S W | ||||||||||
| PMID: | 25886367 | ||||||||||
| 40. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2015 Sep 1;93(1):173-80. | ||||||||||
| Title: | Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation. | ||||||||||
| Author: | Fujita, Mayumi|Imadome, Kaori|Shoji, Yoshimi|Isozaki, Tetsurou|Endo, Satoshi|Yamada, Shigeru|Imai, Takashi | ||||||||||
| PMID: | 26279033 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Growth Metastasis. 2015 Oct 19;8(Suppl 1):95-113. | ||||||||||
| Title: | Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways. | ||||||||||
| Author: | Padavano, Julianna|Henkhaus, Rebecca S|Chen, Hwudaurw|Skovan, Bethany A|Cui, Haiyan|Ignatenko, Natalia A | ||||||||||
| PMID: | 26512205 | ||||||||||
| 42. | |||||||||||
| Journal: | Sci Rep. 2015 Nov 4;5:16067. | ||||||||||
| Title: | Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer. | ||||||||||
| Author: | Niu, Zheyu|Wang, Mengyi|Zhou, Li|Yao, Lutian|Liao, Quan|Zhao, Yupei | ||||||||||
| PMID: | 26530532 | ||||||||||
| 43. | |||||||||||
| Journal: | Mol Cell Biol. 2016 Sep 26;36(20):2596-611. | ||||||||||
| Title: | Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells. | ||||||||||
| Author: | Li, Chunhui|MacDonald, James I S|Talebian, Asghar|Leuenberger, Jennifer|Seah, Claudia|Pasternak, Stephen H|Michnick, Stephen W|Meakin, Susan O | ||||||||||
| PMID: | 27503856 | ||||||||||
| 44. | |||||||||||
| Journal: | Oncol Lett. 2016 Dec;12(6):4677-4684. | ||||||||||
| Title: | Analysis of transcription profile to reveal altered signaling pathways following the overexpression of human desumoylating isopeptidase 2 in pancreatic cancer cells. | ||||||||||
| Author: | Fu, Yu-Yin|Kang, Yu-Huan|Shen, Cong-Cong|Wang, Rui-Xue|Yu, Lin|Li, Xin-Yue|Cui, Dan-Dan|Yang, Jin-Liang|Yao, Yu-Qin|Gou, Lan-Tu | ||||||||||
| PMID: | 28105175 | ||||||||||
| 45. | |||||||||||
| Journal: | Sci Data. 2016 Nov 8;3:160101. | ||||||||||
| Title: | ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells. | ||||||||||
| Author: | Rath, Nicola|Kalna, Gabriela|Clark, William|Olson, Michael F | ||||||||||
| PMID: | 27824338 | ||||||||||
| 46. | |||||||||||
| Journal: | Mol Cancer. 2016 May 4;15(1):32. | ||||||||||
| Title: | ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells. | ||||||||||
| Author: | Fukushima, Hiroto|Yasumoto, Makiko|Ogasawara, Sachiko|Akiba, Jun|Kitasato, Yuhei|Nakayama, Masamichi|Naito, Yoshiki|Ishida, Yusuke|Okabe, Yoshinobu|Yasunaga, Masafumi|Horiuchi, Hiroyuki|Sakamoto, Etsuko|Itadani, Hiraku|Mizuarai, Shinji|Oie, Shinji|Yano, H | ||||||||||
| PMID: | 27145964 | ||||||||||
| 47. | |||||||||||
| Journal: | Mol Cancer Res. 2016 Mar;14(3):267-77. | ||||||||||
| Title: | Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1. | ||||||||||
| Author: | Kent, Oliver A|Mendell, Joshua T|Rottapel, Robert | ||||||||||
| PMID: | 26747707 | ||||||||||
| 48. | |||||||||||
| Journal: | Biochem Pharmacol. 2016 Feb 15;102:107-119. | ||||||||||
| Title: | Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells. | ||||||||||
| Author: | Rivera, Io-Guane|Ordonez, Marta|Presa, Natalia|Gangoiti, Patricia|Gomez-Larrauri, Ana|Trueba, Miguel|Fox, Todd|Kester, Mark|Gomez-Munoz, Antonio | ||||||||||
| PMID: | 26707801 | ||||||||||
| 49. | |||||||||||
| Journal: | Biol Pharm Bull. 2016 Aug 1;39(8):1238-46. | ||||||||||
| Title: | Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study. | ||||||||||
| Author: | Elsayed, Mahitab|Kobayashi, Daisuke|Kubota, Toshio|Matsunaga, Naoya|Murata, Ryusei|Yoshizawa, Yuko|Watanabe, Natsuki|Matsuura, Tohru|Tsurudome, Yuya|Ogino, Takashi|Ohdo, Shigehiro|Shimazoe, Takao | ||||||||||
| PMID: | 27181081 | ||||||||||
| 50. | |||||||||||
| Journal: | Cell Death Dis. 2017 May 18;8(5):e2806. | ||||||||||
| Title: | ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca(2+)/RhoA pathway. | ||||||||||
| Author: | Zhu, Shuai|Zhou, Hai-Yun|Deng, Shi-Chang|Deng, Shi-Jiang|He, Chi|Li, Xiang|Chen, Jing-Yuan|Jin, Yan|Hu, Zhuang-Li|Wang, Fang|Wang, Chun-You|Zhao, Gang | ||||||||||
| PMID: | 28518134 | ||||||||||
| 51. | |||||||||||
| Journal: | Mol Cancer. 2017 Nov 9;16(1):169. | ||||||||||
| Title: | Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer. | ||||||||||
| Author: | Li, Hongzhe|Wang, Xinjing|Wen, Chenlei|Huo, Zhen|Wang, Weishen|Zhan, Qian|Cheng, Dongfeng|Chen, Hao|Deng, Xiaxing|Peng, Chenghong|Shen, Baiyong | ||||||||||
| PMID: | 29121972 | ||||||||||
| 52. | |||||||||||
| Journal: | Cell Rep. 2017 Oct 3;21(1):274-288. | ||||||||||
| Title: | A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts. | ||||||||||
| Author: | Nobis, Max|Herrmann, David|Warren, Sean C|Kadir, Shereen|Leung, Wilfred|Killen, Monica|Magenau, Astrid|Stevenson, David|Lucas, Morghan C|Reischmann, Nadine|Vennin, Claire|Conway, James R W|Boulghourjian, Alice|Zaratzian, Anaiis|Law, Andrew M|Gallego-Orteg | ||||||||||
| PMID: | 28978480 | ||||||||||
| 53. | |||||||||||
| Journal: | Int J Oncol. 2017 Jul;51(1):184-192. | ||||||||||
| Title: | Crizotinib, a MET inhibitor, prevents peritoneal dissemination in pancreatic cancer. | ||||||||||
| Author: | Takiguchi, Soichi|Inoue, Kazuko|Matsusue, Kimihiko|Furukawa, Masayuki|Teramoto, Norihiro|Iguchi, Haruo | ||||||||||
| PMID: | 28498406 | ||||||||||
| 54. | |||||||||||
| Journal: | Oncotarget. 2017 May 23;8(21):34586-34600. | ||||||||||
| Title: | Discovery and characterization of small molecule Rac1 inhibitors. | ||||||||||
| Author: | Arnst, Jamie L|Hein, Ashley L|Taylor, Margaret A|Palermo, Nick Y|Contreras, Jacob I|Sonawane, Yogesh A|Wahl, Andrew O|Ouellette, Michel M|Natarajan, Amarnath|Yan, Ying | ||||||||||
| PMID: | 28410221 | ||||||||||
| 55. | |||||||||||
| Journal: | Neoplasma. 2017;64(1):32-39. | ||||||||||
| Title: | Expression of orphan GPR56 correlates with tumor progression in human epithelial ovarian cancer. | ||||||||||
| Author: | Liu, Z|Huang, Z|Yang, W|Li, Z|Xing, S|Li, H|Hu, B|Li, P | ||||||||||
| PMID: | 27881002 | ||||||||||
| 56. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 17;8(3):4484-4500. | ||||||||||
| Title: | An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer. | ||||||||||
| Author: | Kent, Oliver A|Sandi, Maria-Jose|Burston, Helen E|Brown, Kevin R|Rottapel, Robert | ||||||||||
| PMID: | 27835861 | ||||||||||
| 57. | |||||||||||
| Journal: | Neuro Oncol. 2018 Jan 22;20(2):192-202. | ||||||||||
| Title: | Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha. | ||||||||||
| Author: | Olmez, Inan|Love, Shawn|Xiao, Aizhen|Manigat, Laryssa|Randolph, Peyton|McKenna, Brian D|Neal, Brian P|Boroda, Salome|Li, Ming|Brenneman, Breanna|Abounader, Roger|Floyd, Desiree|Lee, Jeongwu|Nakano, Ichiro|Godlewski, Jakub|Bronisz, Agnieszka|Sulman, Erik P | ||||||||||
| PMID: | 29048560 | ||||||||||
| 58. | |||||||||||
| Journal: | Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1537-1546. | ||||||||||
| Title: | Transforming growth factor-beta modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion. | ||||||||||
| Author: | Stylianou, Andreas|Gkretsi, Vasiliki|Stylianopoulos, Triantafyllos | ||||||||||
| PMID: | 29477748 | ||||||||||
| 59. | |||||||||||
| Journal: | J Am Chem Soc. 2018 Apr 4;140(13):4473-4476. | ||||||||||
| Title: | Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids. | ||||||||||
| Author: | Gebregiworgis, Teklab|Marshall, Christopher B|Nishikawa, Tadateru|Radulovich, Nikolina|Sandi, Maria-Jose|Fang, Zhenhao|Rottapel, Robert|Tsao, Ming-Sound|Ikura, Mitsuhiko | ||||||||||
| PMID: | 29543440 | ||||||||||
| 60. | |||||||||||
| Journal: | Exp Mol Med. 2018 May 1;50(5):59. | ||||||||||
| Title: | Gastrin stimulates pancreatic cancer cell directional migration by activating the Galpha12/13-RhoA-ROCK signaling pathway. | ||||||||||
| Author: | Mu, Ganggang|Ding, Qianshan|Li, Hongyan|Zhang, Li|Zhang, Lingli|He, Ke|Wu, Lu|Deng, Yunchao|Yang, Dongmei|Wu, Lianlian|Xu, Ming|Zhou, Jie|Yu, Honggang | ||||||||||
| PMID: | 29717112 | ||||||||||
| 61. | |||||||||||
| Journal: | NPJ Precis Oncol. 2018 Jan 23;2(1):2. | ||||||||||
| Title: | Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway. | ||||||||||
| Author: | Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling | ||||||||||
| PMID: | 29872721 | ||||||||||
| 62. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2018 Jul 31;37(1):177. | ||||||||||
| Title: | Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis. | ||||||||||
| Author: | Li, Jie|Li, Zhonghu|Jiang, Peng|Peng, Minjie|Zhang, Xi|Chen, Kai|Liu, Hui|Bi, Huaqiang|Liu, Xiangde|Li, Xiaowu | ||||||||||
| PMID: | 30064461 | ||||||||||