Literatures

Primary Site >> Stomach Cancer

Gene >> RHOA

1.
Journal:	Gastroenterology. 2002 Jul;123(1):271-80.
Title:	Identification of plasminogen activator inhibitor-2 as a gastrin-regulated gene: Role of Rho GTPase and menin.
Author:	Varro, Andrea\|Hemers, Elaine\|Archer, Debbie\|Pagliocca, Adelina\|Haigh, Chris\|Ahmed, Suhail\|Dimaline, Rod\|Dockray, Graham J
PMID:	12105855

2.
Journal:	J Cell Sci. 2003 Jul 15;116(Pt 14):3017-26.
Title:	Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration.
Author:	Wroblewski, Lydia E\|Noble, P-J M\|Pagliocca, Adelina\|Pritchard, D Mark\|Hart, C Anthony\|Campbell, Fiona\|Dodson, Andrew R\|Dockray, Graham J\|Varro, Andrea
PMID:	12808021

3.
Journal:	Hum Mol Genet. 2003 Nov 15;12(22):3007-16. Epub 2003 Sep 18.
Title:	E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells.
Author:	Suriano, Gianpaolo\|Oliveira, Maria Jose\|Huntsman, David\|Mateus, Ana Rita\|Ferreira, Paulo\|Casares, Fernando\|Oliveira, Carla\|Carneiro, Fatima\|Machado, Josee Carlos\|Mareel, Marc\|Seruca, Raquel
PMID:	14500541

4.
Journal:	Biochem Biophys Res Commun. 2004 Mar 12;315(3):686-91.
Title:	Expression of seven main Rho family members in gastric carcinoma.
Author:	Pan, Yanglin\|Bi, Feng\|Liu, Na\|Xue, Yan\|Yao, Xuebiao\|Zheng, Yi\|Fan, Daiming
PMID:	14975755

5.
Journal:	Cancer Res. 2004 Mar 1;64(5):1695-702.
Title:	Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis.
Author:	Varro, Andrea\|Noble, P-J M\|Pritchard, D Mark\|Kennedy, Susan\|Hart, C Anthony\|Dimaline, Rod\|Dockray, Graham J
PMID:	14996729

6.
Journal:	Zhonghua Zhong Liu Za Zhi. 2004 Jan;26(1):26-9.
Title:	[The expression and possible function of RhoA in human gastric cancer cell lines].
Author:	Liu, Na\|Bi, Feng\|Pan, Yang-lin\|Xue, Yan\|Zhang, Xing\|Shi, Yong-quan\|Zhang, Yu-mei\|Du, Jing-ping\|Fan, Dai-ming
PMID:	15059348

7.
Journal:	Biochem J. 2004 Jul 15;381(Pt 2):397-403.
Title:	Control of expression of the lectin-like protein Reg-1 by gastrin: role of the Rho family GTPase RhoA and a C-rich promoter element.
Author:	Ashcroft, Felicity J\|Varro, Andrea\|Dimaline, Rod\|Dockray, Graham J
PMID:	15109306

8.
Journal:	Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6239-47.
Title:	Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.
Author:	Liu, Na\|Bi, Feng\|Pan, Yanglin\|Sun, Lijun\|Xue, Yan\|Shi, Yongquan\|Yao, Xuebiao\|Zheng, Yi\|Fan, Daiming
PMID:	15448013

9.
Journal:	J Biol Chem. 2005 Aug 5;280(31):28357-64. Epub 2005 Jun 16.
Title:	Cell adhesion status-dependent histone acetylation is regulated through intracellular contractility-related signaling activities.
Author:	Kim, Yong-Bae\|Yu, Jiyon\|Lee, Sung-Yul\|Lee, Mi-Sook\|Ko, Seong-Gyu\|Ye, Sang-Kyu\|Jong, Hyun-Soon\|Kim, Tae-You\|Bang, Yung-Jue\|Lee, Jung Weon
PMID:	15961394

10.
Journal:	Exp Biol Med (Maywood). 2005 Nov;230(10):731-41.
Title:	The cross talk between protein kinase A- and RhoA-mediated signaling in cancer cells.
Author:	Chen, Yongchang\|Wang, Ying\|Yu, Hao\|Wang, Fengwei\|Xu, Wenrong
PMID:	16246900

11.
Journal:	Oncol Rep. 2005 Dec;14(6):1583-8.
Title:	WNT/PCP signaling pathway and human cancer (review).
Author:	Katoh, Masaru
PMID:	16273260

12.
Journal:	Cancer Res Treat. 2005 Aug;37(4):251-6.
Title:	Characterization of RhoA-mediated chemoresistance in gastric cancer cells.
Author:	Kang, Won Ki\|Lee, Inkyoung\|Park, Chaehwa
PMID:	19956523

13.
Journal:	J Cell Biochem. 2006 Sep 1;99(1):88-95.
Title:	Integrin signaling and cell spreading mediated by phorbol 12-myristate 13-acetate treatment.
Author:	Lee, Mi-Sook\|Kim, Yong-Bae\|Lee, Sung-Yul\|Kim, Jeong-Geun\|Kim, Sung-Hoon\|Ye, Sang-Kyu\|Lee, Jung Weon
PMID:	16598791

14.
Journal:	Int J Oncol. 2007 Mar;30(3):751-5.
Title:	Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer.
Author:	Katoh, Yuriko\|Katoh, Masaru
PMID:	17273778

15.
Journal:	Int J Mol Med. 2007 Mar;19(3):529-33.
Title:	Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	17273804

16.
Journal:	Int J Cancer. 2007 Jun 15;120(12):2600-8.
Title:	IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway.
Author:	Lin, Ming-Tsan\|Lin, Been-Ren\|Chang, Cheng-Chi\|Chu, Chia-Yu\|Su, Hsiang-Ju\|Chen, Szu-Ta\|Jeng, Yung-Ming\|Kuo, Min-Liang
PMID:	17304514

17.
Journal:	Int J Oncol. 2007 May;30(5):1273-7.
Title:	Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	17390031

18.
Journal:	Hum Mol Genet. 2007 Jul 1;16(13):1639-47. Epub 2007 May 17.
Title:	EGFR regulates RhoA-GTP dependent cell motility in E-cadherin mutant cells.
Author:	Mateus, Ana Rita\|Seruca, Raquel\|Machado, Jose Carlos\|Keller, Gisela\|Oliveira, Maria Jose\|Suriano, Gianpaolo\|Luber, Birgit
PMID:	17510211

19.
Journal:	Cancer Biol Ther. 2007 Jun;6(6):832-9. Epub 2007 Mar 26.
Title:	Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
Author:	Katoh, Masaru
PMID:	17568183

20.
Journal:	World J Gastroenterol. 2007 Jul 7;13(25):3517-22.
Title:	RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway.
Author:	Sun, Hua-Wen\|Tong, Shi-Lun\|He, Jie\|Wang, Qi\|Zou, Li\|Ma, Shu-Jing\|Tan, Hai-Yan\|Luo, Jian-Fei\|Wu, Hong-Xue
PMID:	17659701

21.
Journal:	Neoplasia. 2008 Jan;10(1):41-51.
Title:	Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis.
Author:	Cai, Jun\|Niu, Xin\|Chen, Yuying\|Hu, Qingshen\|Shi, Guiying\|Wu, Huacheng\|Wang, Jian\|Yi, Jing
PMID:	18231637

22.
Journal:	J Cell Biochem. 2008 Jun 1;104(3):1102-12.
Title:	Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells.
Author:	Kim, Mi Ha\|Park, Jung Sun\|Chang, Hee Jung\|Baek, Min Kyung\|Kim, Hyeong Rok\|Shin, Boo Ahn\|Ahn, Bong Whan\|Jung, Young Do
PMID:	18247343

23.
Journal:	World J Gastroenterol. 2008 Feb 28;14(8):1175-81.
Title:	Localization and translocation of RhoA protein in the human gastric cancer cell line SGC-7901.
Author:	Tao, Yan\|Chen, Yong-Chang\|Li, Yue-Ying\|Yang, Shu-Qin\|Xu, Wen-Rong
PMID:	18300342

24.
Journal:	Br J Cancer. 2008 Oct 21;99(8):1322-9.
Title:	NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer.
Author:	Murray, D\|Horgan, G\|Macmathuna, P\|Doran, P
PMID:	18827818

25.
Journal:	Mol Cancer Res. 2009 Apr;7(4):570-80.
Title:	RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors.
Author:	Zhang, Siyuan\|Tang, Qiulin\|Xu, Feng\|Xue, Yan\|Zhen, Zipeng\|Deng, Yu\|Liu, Ming\|Chen, Ji\|Liu, Surui\|Qiu, Meng\|Liao, Zhengyin\|Li, Zhiping\|Luo, Deyun\|Shi, Fang\|Zheng, Yi\|Bi, Feng
PMID:	19372585

26.
Journal:	Int J Mol Med. 2009 Jun;23(6):763-9.
Title:	Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	19424602

27.
Journal:	Cancer Sci. 2010 Jan;101(1):87-93.
Title:	Suppression of gastric cancer dissemination by ephrin-B1-derived peptide.
Author:	Tanaka, Masamitsu\|Kamata, Reiko\|Yanagihara, Kazuyoshi\|Sakai, Ryuichi
PMID:	19804421

28.
Journal:	BMC Cancer. 2010 Jan 19;10:20.
Title:	Grp78 promotes the invasion of hepatocellular carcinoma.
Author:	Su, Rongjian\|Li, Zhen\|Li, Hongdan\|Song, Huijuan\|Bao, Cuifen\|Wei, Jia\|Cheng, Liufang
PMID:	20082722

29.
Journal:	Br J Cancer. 2010 Mar 2;102(5):844-51.
Title:	Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.
Author:	Shinto, O\|Yashiro, M\|Kawajiri, H\|Shimizu, K\|Shimizu, T\|Miwa, A\|Hirakawa, K
PMID:	20145621

30.
Journal:	Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2508-16.
Title:	Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-kappaB activity and downregulation of PI3K/AKT/small GTPase signals.
Author:	Ho, Hsieh-Hsun\|Chang, Chi-Sen\|Ho, Wei-Chi\|Liao, Sheng-You\|Wu, Cheng-Hsun\|Wang, Chau-Jong
PMID:	20600540

31.
Journal:	Anticancer Res. 2010 Jun;30(6):2135-43.
Title:	Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways.
Author:	Yang, Mei-Due\|Lai, Kuang-Chi\|Lai, Tung-Yuan\|Hsu, Shu-Chun\|Kuo, Chao-Lin\|Yu, Chun-Shu\|Lin, Meng-Liang\|Yang, Jai-Sing\|Kuo, Hsiu-Maan\|Wu, Shin-Hwar\|Chung, Jing-Gung
PMID:	20651362

32.
Journal:	Int J Cancer. 2011 Mar 1;128(5):1057-68.
Title:	A distinct role of RhoB in gastric cancer suppression.
Author:	Zhou, Jitao\|Zhu, Yajie\|Zhang, Guoyun\|Liu, Na\|Sun, Lijun\|Liu, Ming\|Qiu, Meng\|Luo, Deyun\|Tang, Qiulin\|Liao, Zhengyin\|Zheng, Yi\|Bi, Feng
PMID:	20473933

33.
Journal:	Hum Exp Toxicol. 2011 Apr;30(4):296-306.
Title:	Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.
Author:	Ho, Chin-Chin\|Lai, Kuang-Chi\|Hsu, Shu-Chun\|Kuo, Chao-Lin\|Ma, Chia-Yu\|Lin, Meng-Liang\|Yang, Jai-Sing\|Chung, Jing-Gung
PMID:	20498032

34.
Journal:	BMC Cancer. 2011 Feb 1;11:50.
Title:	A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer.
Author:	Bennett, Gayle\|Sadlier, Denise\|Doran, Peter P\|Macmathuna, Padraic\|Murray, David W
PMID:	21284875

35.
Journal:	Mol Med Rep. 2011 Jan-Feb;4(1):65-9.
Title:	Fibronectin increases RhoA activity through inhibition of PKA in the human gastric cancer cell line SGC-7901.
Author:	Li, Yongjin\|Chen, Yongchang\|Tao, Yan\|Wang, Ying\|Chen, Yuefang\|Xu, Wenrong
PMID:	21461565

36.
Journal:	Zhonghua Zhong Liu Za Zhi. 2011 Apr;33(4):276-9.
Title:	[Expression and significance of RhoA and NF-KappaB in human gastric carcinoma].
Author:	Su, Xiao-juan\|Tang, Zhi-feng\|Li, Qiang\|Li, Hua-long\|Li, Ling-ling\|Liu, Min\|Zhou, Yong-ning
PMID:	21575498

37.
Journal:	Clin Exp Metastasis. 2011 Oct;28(7):627-36.
Title:	RhoA/ROCK signaling mediates plasticity of scirrhous gastric carcinoma motility.
Author:	Matsuoka, Tasuku\|Yashiro, Masakazu\|Kato, Yukihiro\|Shinto, Osamu\|Kashiwagi, Shinichiro\|Hirakawa, Kosei
PMID:	21667311

38.
Journal:	Mol Med Rep. 2011 Nov-Dec;4(6):1115-9.
Title:	Factors influencing RhoA protein distribution in the nucleus.
Author:	Li, Yueying\|Chen, Yongchang\|Xu, Jin
PMID:	21850373

39.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):445-50.
Title:	[The effect of RhoA and proteasome inhibitor MG132 on angiogenesis in tumors].
Author:	Yue, Cai-Xia\|Ma, Ji\|Zhou, Hai-Jun\|Tang, Qiu-Lin\|Li, Li-Lan\|Bi, Feng\|Xue, Yan
PMID:	21866623

40.
Journal:	Int J Cancer. 2012 Feb 15;130(4):787-97.
Title:	Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer.
Author:	Xu, Jianbo\|Zhang, Changhua\|He, Yulong\|Wu, Hui\|Wang, Zhao\|Song, Wu\|Li, Wen\|He, Weiling\|Cai, Shirong\|Zhan, Wenhua
PMID:	21387301

41.
Journal:	J Biol Chem. 2012 Apr 6;287(15):12132-41.
Title:	Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
Author:	Chen, Guang\|Chen, Si-Meng\|Wang, Xiang\|Ding, Xiao-Fei\|Ding, Jian\|Meng, Ling-Hua
PMID:	22337890

42.
Journal:	Hepatogastroenterology. 2012 Nov-Dec;59(120):2523-6.
Title:	Inhibition of RhoA/ROCK signaling pathway promotes the apoptosis of gastric cancer cells.
Author:	Xu, Xiao-Tao\|Song, Qi-Bin\|Yao, Yi\|Ruan, Peng\|Tao, Ze-Zhang
PMID:	22584506

43.
Journal:	Cell Signal. 2013 Feb;25(2):447-56.
Title:	PI3K/Akt-dependent phosphorylation of GSK3beta and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration.
Author:	Liu, Jiaojing\|Zhang, Yujie\|Xu, Rui\|Du, Jun\|Hu, Zhenzhen\|Yang, Ling\|Chen, Yongchang\|Zhu, Yichao\|Gu, Luo
PMID:	23123500

44.
Journal:	Int J Oncol. 2013 Feb;42(2):565-73.
Title:	The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion.
Author:	Fujimoto, Daisuke\|Hirono, Yasuo\|Goi, Takanori\|Katayama, Kanji\|Matsukawa, Shigeru\|Yamaguchi, Akio
PMID:	23242308

45.
Journal:	Cell Signal. 2013 Apr;25(4):931-8.
Title:	STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
Author:	Wei, Zheng\|Jiang, Xian\|Qiao, Haiquan\|Zhai, Bo\|Zhang, Lianfeng\|Zhang, Qiang\|Wu, Yuanhong\|Jiang, Hongchi\|Sun, Xueying
PMID:	23333463

46.
Journal:	PLoS One. 2013 Jun 14;8(6):e66737.
Title:	Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells.
Author:	Gomes, Catarina\|Osorio, Hugo\|Pinto, Marta Teixeira\|Campos, Diana\|Oliveira, Maria Jose\|Reis, Celso A
PMID:	23799130

47.
Journal:	Oncol Rep. 2013 Oct;30(4):1878-82.
Title:	Nuclear translocation of small G protein RhoA via active transportation in gastric cancer cells.
Author:	Xu, Jin\|Li, Yueying\|Yang, Xiaoming\|Chen, Yongchang\|Chen, Min
PMID:	23900609

48.
Journal:	Oncol Lett. 2013 Aug;6(2):463-467.
Title:	Reduced expression of Rho GDP dissociation inhibitor 2 mRNA is associated with lymph node metastasis in gastric carcinoma.
Author:	Shida, Atsuo\|Fujioka, Shuichi\|Takahashi, Naoto\|Aoki, Hiroaki\|Okamoto, Tomoyoshi\|Mitsumori, Norio\|Omura, Nobuo\|Yanaga, Katsuhiko
PMID:	24137348

49.
Journal:	Mol Med Rep. 2014 Apr;9(4):1444-52.
Title:	Type II cGMPdependent protein kinase inhibits RhoA activation in gastric cancer cells.
Author:	Wang, Ying\|Chen, Yongchang\|Li, Yueying\|Lan, Ting\|Qian, Hai
PMID:	24549567

50.
Journal:	Nat Genet. 2014 Jun;46(6):573-82.
Title:	Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
Author:	Wang, Kai\|Yuen, Siu Tsan\|Xu, Jiangchun\|Lee, Siu Po\|Yan, Helen H N\|Shi, Stephanie T\|Siu, Hoi Cheong\|Deng, Shibing\|Chu, Kent Man\|Law, Simon\|Chan, Kok Hoe\|Chan, Annie S Y\|Tsui, Wai Yin\|Ho, Siu Lun\|Chan, Anthony K W\|Man, Jonathan L K\|Foglizzo, Valentina\|Ng, M
PMID:	24816253

51.
Journal:	Nat Genet. 2014 Jun;46(6):583-7.
Title:	Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma.
Author:	Kakiuchi, Miwako\|Nishizawa, Takashi\|Ueda, Hiroki\|Gotoh, Kengo\|Tanaka, Atsushi\|Hayashi, Akimasa\|Yamamoto, Shogo\|Tatsuno, Kenji\|Katoh, Hiroto\|Watanabe, Yoshiaki\|Ichimura, Takashi\|Ushiku, Tetsuo\|Funahashi, Shinichi\|Tateishi, Keisuke\|Wada, Ikuo\|Shimizu, Nobuy
PMID:	24816255

52.
Journal:	Mol Cancer. 2014 May 4;13:100.
Title:	Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway.
Author:	Du, Tao\|Qu, Ying\|Li, Jianfang\|Li, Hao\|Su, Liping\|Zhou, Quan\|Yan, Min\|Li, Chen\|Zhu, Zhenggang\|Liu, Bingya
PMID:	24885567

53.
Journal:	Cancer Cell. 2014 Jul 14;26(1):9-11.
Title:	RhoA mutations identified in diffuse gastric cancer.
Author:	Zhou, Jin\|Hayakawa, Yoku\|Wang, Timothy C\|Bass, Adam J
PMID:	25026207

54.
Journal:	Nature. 2014 Sep 11;513(7517):202-9.
Title:	Comprehensive molecular characterization of gastric adenocarcinoma.
Author:
PMID:	25079317

55.
Journal:	Cancer Res. 2015 Apr 1;75(7):1332-44.
Title:	Chemotherapy-Induced miRNA-29c/Catenin-delta Signaling Suppresses Metastasis in Gastric Cancer.
Author:	Wang, Yuxuan\|Liu, Changzheng\|Luo, Min\|Zhang, Zhengyi\|Gong, Jianan\|Li, Jingjing\|You, Lei\|Dong, Lei\|Su, Rui\|Lin, Haishuang\|Ma, Yanni\|Wang, Fang\|Wang, Yi\|Chen, Jie\|Zhang, Junwu\|Jia, Hongyan\|Kong, Yan\|Yu, Jia
PMID:	25634213

56.
Journal:	Mol Biol (Mosk). 2015 Jan-Feb;49(1):129-37.
Title:	[Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway].
Author:	Yang, G\|Song, J G\|Li, Y\|Gong, S P
PMID:	25916117

57.
Journal:	World J Surg. 2015 Sep;39(9):2289-99.
Title:	The Correlation Between RhoA Expression and Clinicopathological Characteristics in Gastric Cancer Patients After Curative Surgery.
Author:	Huang, Kuo-Hung\|Lan, Yuan-Tzu\|Chen, Ming-Huang\|Chao, Yee\|Lo, Su-Shun\|Li, Anna Fen-Yau\|Wu, Chew-Wun\|Chiou, Shih-Hwa\|Yang, Muh-Hwa\|Shyr, Yi-Ming\|Fang, Wen-Liang
PMID:	26013205

58.
Journal:	Oncol Rep. 2015 Aug;34(2):663-72.
Title:	Depletion of histone deacetylase 1 inhibits metastatic abilities of gastric cancer cells by regulating the miR-34a/CD44 pathway.
Author:	Lin, Lele\|Jiang, Hongpeng\|Huang, Mingkui\|Hou, Xu\|Sun, Xuepu\|Jiang, Xian\|Dong, Xuesong\|Sun, Xueying\|Zhou, Baoguo\|Qiao, Haiquan
PMID:	26035691

59.
Journal:	Gastroenterology. 2015 Oct;149(5):1153-1162.e3.
Title:	Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma.
Author:	Tan, Patrick\|Yeoh, Khay-Guan
PMID:	26073375

60.
Journal:	Cell Rep. 2015 Jul 14;12(2):272-85.
Title:	Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity.
Author:	Yao, Fei\|Kausalya, Jaya P\|Sia, Yee Yen\|Teo, Audrey S M\|Lee, Wah Heng\|Ong, Alicia G M\|Zhang, Zhenshui\|Tan, Joanna H J\|Li, Guoliang\|Bertrand, Denis\|Liu, Xingliang\|Poh, Huay Mei\|Guan, Peiyong\|Zhu, Feng\|Pathiraja, Thushangi Nadeera\|Ariyaratne, Pramila N\|Rao,
PMID:	26146084

61.
Journal:	Cell Biochem Funct. 2015 Oct;33(7):451-61.
Title:	ODAM inhibits RhoA-dependent invasion in breast cancer.
Author:	Lee, Hye-Kyung\|Choung, Han-Wool\|Yang, Young-Il\|Yoon, Hye-Jung\|Park, In Ae\|Park, Joo-Cheol
PMID:	26358398

62.
Journal:	World J Gastroenterol. 2015 Sep 7;21(33):9707-16.
Title:	Contactin 1: A potential therapeutic target and biomarker in gastric cancer.
Author:	Chen, De-Hu\|Yu, Ji-Wei\|Jiang, Bo-Jian
PMID:	26361417

63.
Journal:	Tumour Biol. 2015 Sep;36(10):7385-94.
Title:	Gene mutations in gastric cancer: a review of recent next-generation sequencing studies.
Author:	Lin, Y\|Wu, Z\|Guo, W\|Li, J
PMID:	26364057

64.
Journal:	Int J Clin Exp Med. 2015 Aug 15;8(8):14410-5. eCollection 2015.
Title:	Effect of RhoA gene silencing on proliferation and migration of gastric MGC-803 cells.
Author:	Duan, Ju-Tao\|Wang, Xi-Mo\|Zhang, Shu-Quan\|Zhao, Guan-Jie
PMID:	26550428

65.
Journal:	Gastric Cancer. 2016 Apr;19(2):403-11.
Title:	RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases.
Author:	Ushiku, Tetsuo\|Ishikawa, Shumpei\|Kakiuchi, Miwako\|Tanaka, Atsushi\|Katoh, Hiroto\|Aburatani, Hiroyuki\|Lauwers, Gregory Y\|Fukayama, Masashi
PMID:	25823974

66.
Journal:	J Clin Pathol. 2016 Jan;69(1):70-5.
Title:	Clinicopathological characteristics of RHOA mutations in a Central European gastric cancer cohort.
Author:	Rocken, Christoph\|Behrens, Hans-Michael\|Boger, Christine\|Kruger, Sandra
PMID:	26251521

67.
Journal:	Gastric Cancer. 2016 Apr;19(2):326-8.
Title:	RHOA mutation may be associated with diffuse-type gastric cancer progression, but is it gain or loss?
Author:	Maeda, Masahiro\|Ushijima, Toshikazu
PMID:	26296386

68.
Journal:	Cancer Lett. 2016 Jan 1;370(1):39-55.
Title:	Fbxw7 regulates tumor apoptosis, growth arrest and the epithelial-to-mesenchymal transition in part through the RhoA signaling pathway in gastric cancer.
Author:	Li, Hui\|Wang, Ziwei\|Zhang, Wei\|Qian, Kun\|Xu, Wei\|Zhang, Shouru
PMID:	26458995

69.
Journal:	Oncotarget. 2016 Feb 16;7(7):8055-66.
Title:	Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites.
Author:	Lim, Byungho\|Kim, Chan\|Kim, Jeong-Hwan\|Kwon, Woo Sun\|Lee, Won Seok\|Kim, Jeong Min\|Park, Jun Yong\|Kim, Hyo Song\|Park, Kyu Hyun\|Kim, Tae Soo\|Park, Jong-Lyul\|Chung, Hyun Cheol\|Rha, Sun Young\|Kim, Seon-Young
PMID:	26811494

70.
Journal:	J Transl Med. 2016 Feb 1;14:32.
Title:	CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells.
Author:	Deng, Wenjie\|Gu, Luo\|Li, Xiaojie\|Zheng, Jianchao\|Zhang, Yujie\|Duan, Biao\|Cui, Jie\|Dong, Jing\|Du, Jun
PMID:	26830684

71.
Journal:	J Pathol. 2016 Oct;240(2):137-48.
Title:	Comprehensive mutation profiling of mucinous gastric carcinoma.
Author:	Rokutan, Hirofumi\|Hosoda, Fumie\|Hama, Natsuko\|Nakamura, Hiromi\|Totoki, Yasushi\|Furukawa, Eisaku\|Arakawa, Erika\|Ohashi, Shoko\|Urushidate, Tomoko\|Satoh, Hironori\|Shimizu, Hiroko\|Igarashi, Keiko\|Yachida, Shinichi\|Katai, Hitoshi\|Taniguchi, Hirokazu\|Fukayama,
PMID:	27313181

72.
Journal:	Ann Surg Oncol. 2016 Dec;23(13):4238-4246.
Title:	Increased RhoA Activity Predicts Worse Overall Survival in Patients Undergoing Surgical Resection for Lauren Diffuse-Type Gastric Adenocarcinoma.
Author:	Chang, Kevin K\|Cho, Soo-Jeong\|Yoon, Changhwan\|Lee, Jun Ho\|Park, Do Joong\|Yoon, Sam S
PMID:	27364501

73.
Journal:	Biomed Rep. 2016 Aug;5(2):151-154.
Title:	MicroRNAs in hereditary diffuse gastric cancer.
Author:	Suarez-Arriaga, Mayra-Cecilia\|Ribas-Aparicio, Rosa-Maria\|Ruiz-Tachiquin, Martha-Eugenia
PMID:	27446532

74.
Journal:	Neoplasia. 2016 Aug;18(8):500-11.
Title:	Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer.
Author:	Hinsenkamp, Isabel\|Schulz, Sandra\|Roscher, Mareike\|Suhr, Anne-Maria\|Meyer, Bjorn\|Munteanu, Bogdan\|Fuchser, Jens\|Schoenberg, Stefan O\|Ebert, Matthias P A\|Wangler, Bjorn\|Hopf, Carsten\|Burgermeister, Elke
PMID:	27566106

75.
Journal:	Oncotarget. 2016 Oct 4;7(40):65418-65428.
Title:	Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies.
Author:	Lan, Ting\|Pang, Ji\|Wu, Yan\|Zhu, Miaolin\|Yao, Xiaoyuan\|Wu, Min\|Qian, Hai\|Zhang, Zhenyu\|Gao, Jizong\|Chen, Yongchang
PMID:	27589842

76.
Journal:	Nat Genet. 2016 Oct;48(10):1288-94.
Title:	Unsupervised detection of cancer driver mutations with parsimony-guided learning.
Author:	Kumar, Runjun D\|Swamidass, S Joshua\|Bose, Ron
PMID:	27618449

77.
Journal:	Exp Hematol. 2016 Dec;44(12):1123-1129.
Title:	Variegated RHOA mutations in human cancers.
Author:	Kataoka, Keisuke\|Ogawa, Seishi
PMID:	27693615

78.
Journal:	Oncotarget. 2016 Dec 20;7(51):84798-84809.
Title:	C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA.
Author:	Kaida, Takayoshi\|Nitta, Hidetoshi\|Kitano, Yuki\|Yamamura, Kensuke\|Arima, Kota\|Izumi, Daisuke\|Higashi, Takaaki\|Kurashige, Junji\|Imai, Katsunori\|Hayashi, Hiromitsu\|Iwatsuki, Masaaki\|Ishimoto, Takatsugu\|Hashimoto, Daisuke\|Yamashita, Yoichi\|Chikamoto, Akira\|Im
PMID:	27756879

79.
Journal:	Oncotarget. 2016 Dec 6;7(49):81435-81451.
Title:	Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer.
Author:	Chang, Hae Ryung\|Nam, Seungyoon\|Lee, Jinhyuk\|Kim, Jin-Hee\|Jung, Hae Rim\|Park, Hee Seo\|Park, Sungjin\|Ahn, Young Zoo\|Huh, Iksoo\|Balch, Curt\|Ku, Ja-Lok\|Powis, Garth\|Park, Taesung\|Jeong, Jin-Hyun\|Kim, Yon Hui
PMID:	27806312

80.
Journal:	Med Sci Monit. 2016 Dec 1;22:4679-4691.
Title:	MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion: Roles of RhoA.
Author:	Chen, Zhuo\|Liu, Shengnan\|Xia, Yuan\|Wu, Kejian
PMID:	27904131

81.
Journal:	Gastric Cancer. 2017 Mar;20(2):274-285.
Title:	Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression.
Author:	Yoon, Jung Hwan\|Choi, Won Suk\|Kim, Olga\|Choi, Byung Joon\|Nam, Suk Woo\|Lee, Jung Young\|Park, Won Sang
PMID:	27250838

82.
Journal:	Sci China Life Sci. 2017 Feb;60(2):126-137.
Title:	Genomic landscape of gastric cancer: molecular classification and potential targets.
Author:	Guo, Jiawei\|Yu, Weiwei\|Su, Hui\|Pang, Xiufeng
PMID:	27460193

83.
Journal:	Oncogene. 2017 Jun 8;36(23):3213-3222.
Title:	Rho GTPases: Anti- or pro-neoplastic targets?
Author:	Zandvakili, I\|Lin, Y\|Morris, J C\|Zheng, Y
PMID:	27991930

84.
Journal:	Gastroenterology. 2017 Aug;153(2):536-549.e26.
Title:	Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Author:	Cho, Soo Young\|Park, Jun Won\|Liu, Yang\|Park, Young Soo\|Kim, Ju Hee\|Yang, Hanna\|Um, Hyejin\|Ko, Woo Ri\|Lee, Byung Il\|Kwon, Sun Young\|Ryu, Seung Wan\|Kwon, Chae Hwa\|Park, Do Youn\|Lee, Jae-Hyuk\|Lee, Sang Il\|Song, Kyu Sang\|Hur, Hoon\|Han, Sang-Uk\|Chang, Heekyung
PMID:	28522256

85.
Journal:	Cell Rep. 2017 May 23;19(8):1495-1502.
Title:	YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis.
Author:	Qiao, Yiting\|Chen, Jianxiang\|Lim, Ying Bena\|Finch-Edmondson, Megan Louise\|Seshachalam, Veerabrahma Pratap\|Qin, Lei\|Jiang, Tingting\|Low, Boon Chuan\|Singh, Himanshu\|Lim, Chwee Teck\|Sudol, Marius
PMID:	28538170

86.
Journal:	Med Sci Monit. 2017 Jun 18;23:2979-2984.
Title:	Expressions of Ras Homolog Gene Family, Member A (RhoA) and Cyclooxygenase-2 (COX-2) Proteins in Early Gastric Cancer and Their Role in the Development of Gastric Cancer.
Author:	Song, Li\|Guo, Yali\|Xu, Baohong
PMID:	28624843

87.
Journal:	Med Sci Monit. 2017 Jun 27;23:3154-3160.
Title:	P53 and Protein Phosphorylation Regulate the Oncogenic Role of Epithelial Cell Transforming 2 (ECT2).
Author:	Chen, Yan\|Tian, Ping\|Liu, Yi
PMID:	28654632

88.
Journal:	Oncol Rep. 2017 Aug;38(2):1133-1139.
Title:	MicroRNA-31 inhibits tumor invasion and metastasis by targeting RhoA in human gastric cancer.
Author:	Ge, Fulin\|Wang, Changzheng\|Wang, Weihua\|Liu, Wenhui\|Wu, Benyan
PMID:	28656284

89.
Journal:	Exp Biol Med (Maywood). 2017 Dec;242(18):1842-1847.
Title:	MicroRNA-31 inhibits RhoA-mediated tumor invasion and chemotherapy resistance in MKN-45 gastric adenocarcinoma cells.
Author:	Korourian, Alireza\|Roudi, Raheleh\|Shariftabrizi, Ahmad\|Madjd, Zahra
PMID:	28836853

90.
Journal:	Theranostics. 2017 Aug 2;7(13):3338-3353.
Title:	MicroRNA-647 Targets SRF-MYH9 Axis to Suppress Invasion and Metastasis of Gastric Cancer.
Author:	Ye, Gengtai\|Huang, Kunzhai\|Yu, Jiang\|Zhao, Liying\|Zhu, Xianjun\|Yang, Qingbin\|Li, Wende\|Jiang, Yuming\|Zhuang, Baoxiong\|Liu, Hao\|Shen, Zhiyong\|Wang, Da\|Yan, Li\|Zhang, Lei\|Zhou, Haipeng\|Hu, Yanfeng\|Deng, Haijun\|Liu, Hao\|Li, Guoxin\|Qi, Xiaolong
PMID:	28900514

91.
Journal:	Histopathology. 2018 Mar;72(4):556-568.
Title:	Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.
Author:	Kwon, Chae H\|Kim, Young K\|Lee, Sojeong\|Kim, Ahrong\|Park, Hye J\|Choi, Yuri\|Won, Yeo J\|Park, Do Y\|Lauwers, Gregory Y
PMID:	28873240

92.
Journal:	Cancer Sci. 2018 Jan;109(1):84-93.
Title:	Rac GTPase activating protein 1 promotes oncogenic progression of epithelial ovarian cancer.
Author:	Wang, Chuanjiang\|Wang, Wenxia\|Liu, Yujuan\|Yong, Min\|Yang, Yamei\|Zhou, Honggui
PMID:	29095547

93.
Journal:	Biochem Biophys Res Commun. 2018 Jan 8;495(2):1942-1947.
Title:	Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells.
Author:	Miyamoto, Shingo\|Nagamura, Yuko\|Nakabo, Ayaka\|Okabe, Akira\|Yanagihara, Kazuyoshi\|Fukami, Kiyoko\|Sakai, Ryuichi\|Yamaguchi, Hideki
PMID:	29247652

94.
Journal:	Exp Mol Med. 2018 Apr 6;50(4):6.
Title:	Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer.
Author:	Choi, Ji-Hye\|Kim, Young-Bae\|Ahn, Ji Mi\|Kim, Min Jae\|Bae, Won Jung\|Han, Sang-Uk\|Woo, Hyun Goo\|Lee, Dakeun
PMID:	29622765

95.
Journal:	Mol Carcinog. 2018 Sep;57(9):1144-1155.
Title:	PIEZO1 functions as a potential oncogene by promoting cell proliferation and migration in gastric carcinogenesis.
Author:	Zhang, Jinglin\|Zhou, Yuhang\|Huang, Tingting\|Wu, Feng\|Liu, Liping\|Kwan, Johnny S H\|Cheng, Alfred S L\|Yu, Jun\|To, Ka Fai\|Kang, Wei
PMID:	29683214

96.
Journal:	Biomed Pharmacother. 2018 Jul;103:823-828.
Title:	Inhibition of gastric cancer by local anesthetic bupivacaine through multiple mechanisms independent of sodium channel blockade.
Author:	Dan, Jiapeng\|Gong, Xiaodan\|Li, Dezhan\|Zhu, Guanhua\|Wang, Lishen\|Li, Fang
PMID:	29684861

97.
Journal:	Med Sci Monit. 2018 Apr 24;24:2508-2517.
Title:	Overexpression of Myosin Phosphatase Target Subunit 1 (MYPT1) Inhibits Tumor Progression and Metastasis of Gastric Cancer.
Author:	Wang, Fengyong\|Sun, Yuanshui
PMID:	29687789

98.
Journal:	Biol Proced Online. 2018 May 1;20:10.
Title:	Blockade of ITGA2 Induces Apoptosis and Inhibits Cell Migration in Gastric Cancer.
Author:	Chuang, Yu-Chang\|Wu, Hsin-Yi\|Lin, Yu-Ling\|Tzou, Shey-Cherng\|Chuang, Cheng-Hsun\|Jian, Ting-Yan\|Chen, Pin-Rong\|Chang, Yuan-Ching\|Lin, Chi-Hsin\|Huang, Tse-Hung\|Wang, Chao-Ching\|Chan, Yi-Lin\|Liao, Kuang-Wen
PMID:	29743821

99.
Journal:	Neoplasma. 2018 Mar 14;65(3):360-366.
Title:	Identification of recurrent risk-related genes and establishment of support vector machine prediction model for gastric cancer.
Author:	Liu, B\|Tan, J\|Wang, X\|Liu, X
PMID:	29788739

100.
Journal:	Oncotarget. 2018 May 1;9(33):23198-23207.
Title:	DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
Author:	Nishizawa, Takashi\|Nakano, Kiyotaka\|Harada, Aya\|Kakiuchi, Miwako\|Funahashi, Shin-Ichi\|Suzuki, Masami\|Ishikawa, Shumpei\|Aburatani, Hiroyuki
PMID:	29796182

101.
Journal:	Biomed Pharmacother. 2018 Jul;103:1708-1719.
Title:	Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice.
Author:	Wang, Zheng-Hua\|Zhan-Sheng, Hu
PMID:	29864961

102.
Journal:	J Cell Biochem. 2018 Sep 14.
Title:	Suppression of BMX-ARHGAP fusion gene inhibits epithelial-mesenchymal transition in gastric cancer cells via RhoA-mediated blockade of JAK/STAT axis.
Author:	Xu, Xiao-Feng\|Wang, Jian-Jiang\|Ding, Li\|Ye, Jin-Song\|Huang, Li-Juan\|Tao, Lan\|Gao, Feng\|Ji, Yong
PMID:	30216523

103.
Journal:	Cell Stem Cell. 2018 Oct 13. pii: S1934-5909(18)30480-6.
Title:	A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.
Author:	Yan, Helen H N\|Siu, Hoi Cheong\|Law, Simon\|Ho, Siu Lun\|Yue, Sarah S K\|Tsui, Wai Yin\|Chan, Dessy\|Chan, April S\|Ma, Stephanie\|Lam, Ka On\|Bartfeld, Sina\|Man, Alice H Y\|Lee, Bernard C H\|Chan, Annie S Y\|Wong, Jason W H\|Cheng, Priscilla S W\|Chan, Anthony K W\|Zha
PMID:	30344100