Primary Site >> Colorectal Cancer

Gene >> RHOA

Journal: Gene. 1994 Jul 8;144(2):229-36.
Title: Utilization of multiple polyadenylation signals in the human RHOA protooncogene.
Author: Moscow, J A|He, R|Gudas, J M|Cowan, K H
PMID: 8039707
Journal: Exp Cell Res. 1999 Dec 15;253(2):533-40.
Title: Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells.
Author: Mohri, T|Adachi, Y|Ikehara, S|Hioki, K|Tokunaga, R|Taketani, S
PMID: 10585277
Journal: J Cell Biol. 2000 Jan 24;148(2):253-8.
Title: RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism.
Author: O'Connor, K L|Nguyen, B K|Mercurio, A M
PMID: 10648558
Journal: Br J Cancer. 2000 Feb;82(4):905-12.
Title: Manumycin inhibits ras signal transduction pathway and induces apoptosis in COLO320-DM human colon tumour cells.
Author: Di Paolo, A|Danesi, R|Nardini, D|Bocci, G|Innocenti, F|Fogli, S|Barachini, S|Marchetti, A|Bevilacqua, G|Del Tacca, M
PMID: 10732765
Journal: FASEB J. 2000 Nov;14(14):2329-38.
Title: Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways.
Author: Attoub, S|Noe, V|Pirola, L|Bruyneel, E|Chastre, E|Mareel, M|Wymann, M P|Gespach, C
PMID: 11053255
Journal: FASEB J. 2001 Feb;15(2):351-61.
Title: Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells.
Author: Emami, S|Le Floch , N|Bruyneel, E|Thim, L|May, F|Westley, B|Rio, M|Mareel, M|Gespach, C
PMID: 11156951
Journal: J Biol Chem. 2002 Apr 26;277(17):15207-14. Epub 2002 Feb 13.
Title: Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells.
Author: Li, Xiaodong|Saint-Cyr-Proulx, Etienne|Aktories, Klaus|Lamarche-Vane, Nathalie
PMID: 11844789
Journal: Carcinogenesis. 2002 Mar;23(3):521-8.
Title: Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.
Author: Agarwal, Banke|Halmos, Balazs|Feoktistov, Aleksander S|Protiva, Petr|Ramey, William G|Chen, Ming|Pothoulakis, Charalabos|Lamont, J Thomas|Holt, Peter R
PMID: 11895868
Journal: Zhonghua Yi Xue Za Zhi. 2002 Mar;82(5):348-51.
Title: [RhoA gene expression in colorectal carcinoma].
Author: Wang, Hao|Chen, Yuxia|Cao, Dongmei|Zhang, Ye|Meng, Ronggui|Lu, Jian
PMID: 11953197
Journal: Cancer Res. 2002 Aug 15;62(16):4829-35.
Title: Bombesin stimulates invasion and migration of Isreco1 colon carcinoma cells in a Rho-dependent manner.
Author: Saurin, Jean-Christophe|Fallavier, Marjorie|Sordat, Bernard|Gevrey, Jean-Claude|Chayvialle, Jean-Alain|Abello, Jacques
PMID: 12183443
Journal: Oncogene. 2002 Oct 3;21(44):6740-50.
Title: Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways.
Author: Debruyne, P R|Bruyneel, E A|Karaguni, I-M|Li, Xd|Flatau, G|Muller, O|Zimber, A|Gespach, C|Mareel, M M
PMID: 12360401
Journal: Cancer Cell. 2003 Jul;4(1):67-79.
Title: ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Author: Vial, Emmanuel|Sahai, Erik|Marshall, Christopher J
PMID: 12892714
Journal: Clin Exp Metastasis. 2003;20(6):561-7.
Title: Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
Author: Kusama, Toshiyuki|Mukai, Mutsuko|Tatsuta, Masaharu|Matsumoto, Yoshirou|Nakamura, Hiroyuki|Inoue, Masahiro
PMID: 14598891
Journal: EMBO J. 2003 Nov 17;22(22):6161-73.
Title: Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility.
Author: Oliveira, Maria Jose|Van Damme, Jozef|Lauwaet, Tineke|De Corte, Veerle|De Bruyne, Georges|Verschraegen, Gerda|Vaneechoutte, Mario|Goethals, Marc|Ahmadian, Mohammad Reza|Muller, Oliver|Vandekerckhove, Joel|Mareel, Marc|Leroy, Ancy
PMID: 14609961
Journal: FASEB J. 2004 Jan;18(1):140-2. Epub 2003 Nov 20.
Title: Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion.
Author: Nubel, Tobias|Dippold, Wolfgang|Kleinert, Hartmut|Kaina, Bernd|Fritz, Gerhard
PMID: 14630701
Journal: Mol Carcinog. 2004 Apr;39(4):206-20.
Title: LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane.
Author: Ota, Takahide|Maeda, Masayo|Suto, Shiho|Tatsuka, Masaaki
PMID: 15057873
Journal: FASEB J. 2004 Jun;18(9):1016-8. Epub 2004 Apr 1.
Title: Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac.
Author: De Wever, Olivier|Nguyen, Quang-De|Van Hoorde, Leen|Bracke, Marc|Bruyneel, Erik|Gespach, Christian|Mareel, Marc
PMID: 15059978
Journal: Cancer Res. 2004 Dec 15;64(24):8994-9001.
Title: Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis.
Author: Croft, Daniel R|Sahai, Erik|Mavria, Georgia|Li, Shuixing|Tsai, Jeff|Lee, William M F|Marshall, Christopher J|Olson, Michael F
PMID: 15604264
Journal: Oncogene. 2005 Dec 15;24(56):8240-51.
Title: Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment.
Author: Nguyen, Quang-De|De Wever, Olivier|Bruyneel, Erik|Hendrix, An|Xie, Wan-Zhuo|Lombet, Alain|Leibl, Martin|Mareel, Marc|Gieseler, Frank|Bracke, Marc|Gespach, Christian
PMID: 16091733
Journal: Oncogene. 2005 Nov 24;24(53):7859-68.
Title: A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.
Author: Fang, Wei Bin|Brantley-Sieders, Dana M|Parker, Monica A|Reith, Alastair D|Chen, Jin
PMID: 16103880
Journal: Ai Zheng. 2005 Sep;24(9):1064-70.
Title: [Effect of NGX6 on gene expression profile of colon carcinoma cell line HT-29].
Author: Liu, Fen|Wang, Xiao-Yan|Lian, Ping|Xiao, Zhi-Ming|Shen, Shou-Rong|Ma, Jian|Xiong, Wei
PMID: 16159426
Journal: Cancer Res. 2005 Dec 1;65(23):10938-45.
Title: Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease.
Author: Bellovin, David I|Bates, Richard C|Muzikansky, Alona|Rimm, David L|Mercurio, Arthur M
PMID: 16322241
Journal: Exp Cell Res. 2006 Feb 15;312(4):387-400.
Title: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
Author: Carothers, Adelaide M|Javid, Sara H|Moran, Amy E|Hunt, Daniel H|Redston, Mark|Bertagnolli, Monica M
PMID: 16368433
Journal: Cancer Res. 2006 Mar 15;66(6):3153-61.
Title: PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
Author: Fiordalisi, James J|Keller, Patricia J|Cox, Adrienne D
PMID: 16540666
Journal: Oncogene. 2006 Nov 2;25(52):6959-67. Epub 2006 May 22.
Title: Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma.
Author: Bellovin, D I|Simpson, K J|Danilov, T|Maynard, E|Rimm, D L|Oettgen, P|Mercurio, A M
PMID: 16715134
Journal: Mol Cancer Ther. 2006 Aug;5(8):2070-7.
Title: Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
Author: Nguyen, Quang-De|Rodrigues, Sylvie|Rodrigue, Christelle M|Rivat, Christine|Grijelmo, Clara|Bruyneel, Erik|Emami, Shahin|Attoub, Samir|Gespach, Christian
PMID: 16928828
Journal: Cancer Res. 2006 Dec 15;66(24):11700-8.
Title: RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility.
Author: Chang, Yu-Wen E|Marlin, Jerry W|Chance, Terry W|Jakobi, Rolf
PMID: 17178865
Journal: Cell Signal. 2007 Feb;19(2):261-8. Epub 2006 Aug 9.
Title: MAGI-3 regulates LPA-induced activation of Erk and RhoA.
Author: Zhang, Huanchun|Wang, Dongsheng|Sun, Hong|Hall, Randy A|Yun, C Chris
PMID: 16904289
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: Int J Oncol. 2007 May;30(5):1273-7.
Title: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17390031
Journal: Cancer Res. 2007 Apr 1;67(7):2922-6.
Title: PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Author: Wang, Haihe|Quah, Samantha Yiling|Dong, Jing Ming|Manser, Edward|Tang, Jing Ping|Zeng, Qi
PMID: 17409395
Journal: Dig Dis Sci. 2008 Feb;53(2):467-73. Epub 2007 Jun 28.
Title: The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer.
Author: Takami, Yoji|Higashi, Morihiro|Kumagai, Shinpei|Kuo, Paul C|Kawana, Hidetada|Koda, Keiji|Miyazaki, Masaru|Harigaya, Kenichi
PMID: 17597401
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Cancer Lett. 2008 Aug 8;266(2):263-74.
Title: Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion.
Author: Denys, Hannelore|Derycke, Lara|Hendrix, An|Westbroek, Wendy|Gheldof, Alexander|Narine, Kishan|Pauwels, Patrick|Gespach, Christian|Bracke, Marc|De Wever, Olivier
PMID: 18423981
Journal: Mol Pharmacol. 2008 Aug;74(2):476-84.
Title: Activation of nuclear factor-kappa B pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells.
Author: Riganti, Chiara|Doublier, Sophie|Costamagna, Costanzo|Aldieri, Elisabetta|Pescarmona, Gianpiero|Ghigo, Dario|Bosia, Amalia
PMID: 18463201
Journal: J Neurochem. 2008 Oct;107(2):418-31.
Title: LIM-only protein 4 interacts directly with the repulsive guidance molecule A receptor Neogenin.
Author: Schaffar, Gregor|Taniguchi, Junko|Brodbeck, Tanja|Meyer, Axel H|Schmidt, Martin|Yamashita, Toshihide|Mueller, Bernhard K
PMID: 18702663
Journal: Int J Cancer. 2008 Dec 1;123(11):2543-56.
Title: Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways.
Author: Jaffe, Tamara|Schwartz, Betty
PMID: 18767036
Journal: Cancer Res. 2008 Oct 15;68(20):8210-20.
Title: Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion.
Author: Joshi, Bharat|Strugnell, Scott S|Goetz, Jacky G|Kojic, Liliana D|Cox, Michael E|Griffith, Obi L|Chan, Simon K|Jones, Steven J|Leung, Sher-Ping|Masoudi, Hamid|Leung, Samuel|Wiseman, Sam M|Nabi, Ivan R
PMID: 18922892
Journal: Mol Cancer Res. 2008 Oct;6(10):1607-20.
Title: RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells.
Author: Doublier, Sophie|Riganti, Chiara|Voena, Claudia|Costamagna, Costanzo|Aldieri, Elisabetta|Pescarmona, Gianpiero|Ghigo, Dario|Bosia, Amalia
PMID: 18922976
Journal: J Cell Biol. 2008 Nov 17;183(4):697-710.
Title: RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells.
Author: Ordonez-Moran, Paloma|Larriba, Maria Jesus|Palmer, Hector G|Valero, Ruth A|Barbachano, Antonio|Dunach, Mireia|de Herreros, Antonio Garcia|Villalobos, Carlos|Berciano, Maria Teresa|Lafarga, Miguel|Munoz, Alberto
PMID: 19015318
Journal: J Exp Clin Cancer Res. 2009 Apr 18;28:52.
Title: Inhibitory effects of adenovirus mediated tandem expression of RhoA and RhoC shRNAs in HCT116 cells.
Author: Liu, Xiang-Ping|Wang, Hai-Bo|Yang, Kun|Sui, Ai-Hua|Shi, Qiang|Qu, Shen
PMID: 19374769
Journal: Clin Chem Lab Med. 2009;47(7):811-7.
Title: Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.
Author: Wang, Hai-bo|Liu, Xiang-ping|Liang, Jun|Yang, Kun|Sui, Ai-hua|Liu, Yan-jun
PMID: 19499974
Journal: Br J Cancer. 2009 Oct 20;101(8):1374-81.
Title: Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells.
Author: Ueno, K|Hazama, S|Mitomori, S|Nishioka, M|Suehiro, Y|Hirata, H|Oka, M|Imai, K|Dahiya, R|Hinoda, Y
PMID: 19773752
Journal: World J Gastroenterol. 2009 Sep 28;15(36):4547-55.
Title: Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action.
Author: Sun, Hong|Ren, Juan|Zhu, Qing|Kong, Fan-Zhong|Wu, Lei|Pan, Bo-Rong
PMID: 19777613
Journal: IUBMB Life. 2009 Oct;61(10):1001-9.
Title: Aquaporin-1 activity of plasma membrane affects HT20 colon cancer cell migration.
Author: Jiang, Yong
PMID: 19787701
Journal: Int J Cancer. 2010 Feb 15;126(4):852-63.
Title: Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells.
Author: Yang, Zhihong|Xiao, Hang|Jin, Huanyu|Koo, Phillip T|Tsang, Dorothea J|Yang, Chung S
PMID: 19626588
Journal: Cell Biol Int. 2010 Jan 25;34(2):213-23.
Title: Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.
Author: Paduch, Roman|Kandefer-Szerszen, Martyna|Szuster-Ciesielska, Agnieszka|Plewka, Krzysztof
PMID: 19947919
Journal: Int J Cancer. 2010 Sep 1;127(5):1220-9.
Title: Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1.
Author: Wang, Lei|Kuang, Lisha|Pan, Xinhua|Liu, Junchen|Wang, Qian|Du, Bing|Li, Dali|Luo, Jian|Liu, Mingyao|Hou, Aijun|Qian, Min
PMID: 20017136
Journal: Eur J Cancer. 2010 May;46(8):1445-55.
Title: Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.
Author: Rebillard, Amelie|Jouan-Lanhouet, Sandrine|Jouan, Elodie|Legembre, Patrick|Pizon, Mathieu|Sergent, Odile|Gilot, David|Tekpli, Xavier|Lagadic-Gossmann, Dominique|Dimanche-Boitrel, Marie-Therese
PMID: 20202822
Journal: J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):355-61.
Title: The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling.
Author: Ordonez-Moran, Paloma|Alvarez-Diaz, Silvia|Valle, Noelia|Larriba, Maria Jesus|Bonilla, Felix|Munoz, Alberto
PMID: 20223287
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2010 Feb;32(1):46-50.
Title: [Effects of K-ras gene mutation on colon cancer cell line Caco-2 metastasis by regulating E-cadherin/beta-catenin/p120 protein complex formation and RhoA protein activity].
Author: Li, Jing-nan|Li, Xiao|Qian, Jia-ming|Lu, Xin-qing|Yang, Hong
PMID: 20236587
Journal: J Neurochem. 2010 Jun;113(6):1589-97.
Title: A central role for RhoA during oligodendroglial maturation in the switch from netrin-1-mediated chemorepulsion to process elaboration.
Author: Rajasekharan, Sathyanath|Bin, Jenea M|Antel, Jack P|Kennedy, Timothy E
PMID: 20367748
Journal: Am J Physiol Cell Physiol. 2010 Aug;299(2):C454-63.
Title: PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells.
Author: Espejo, Rosario|Rengifo-Cam, William|Schaller, Michael D|Evers, B Mark|Sastry, Sarita K
PMID: 20519451
Journal: J Exp Clin Cancer Res. 2010 Sep 9;29:123.
Title: Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.
Author: Wang, Haibo|Zhao, Gang|Liu, Xiangping|Sui, Aihua|Yang, Kun|Yao, Ruyong|Wang, Zongbao|Shi, Qiang
PMID: 20828398
Journal: Cancer Lett. 2011 Feb 28;301(2):151-60.
Title: miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.
Author: Liu, Ming|Lang, Nan|Chen, Xiangzhen|Tang, Qiulin|Liu, Surui|Huang, Juan|Zheng, Yi|Bi, Feng
PMID: 21186079
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G749-60.
Title: Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.
Author: Belo, Angelica|Cheng, Kunrong|Chahdi, Ahmed|Shant, Jasleen|Xie, Guofeng|Khurana, Sandeep|Raufman, Jean-Pierre
PMID: 21273532
Journal: Biochem Pharmacol. 2011 May 15;81(10):1192-200.
Title: Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Author: Kuang, Lisha|Wang, Lei|Wang, Qian|Zhao, Qufei|Du, Bing|Li, Dali|Luo, Jian|Liu, Mingyao|Hou, Aijun|Qian, Min
PMID: 21377450
Journal: Cancer Res. 2011 May 1;71(9):3246-56.
Title: mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
Author: Gulhati, Pat|Bowen, Kanika A|Liu, Jianyu|Stevens, Payton D|Rychahou, Piotr G|Chen, Min|Lee, Eun Y|Weiss, Heidi L|O'Connor, Kathleen L|Gao, Tianyan|Evers, B Mark
PMID: 21430067
Journal: Mol Cancer. 2011 Jul 3;10:79.
Title: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Author: Nakashima, Masanori|Adachi, Seiji|Yasuda, Ichiro|Yamauchi, Takahiro|Kawaguchi, Junji|Hanamatsu, Toshimasa|Yoshioka, Takashi|Okano, Yukio|Hirose, Yoshinobu|Kozawa, Osamu|Moriwaki, Hisataka
PMID: 21722395
Journal: Mol Biol Cell. 2011 Oct;22(19):3734-46.
Title: The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth.
Author: Antoine-Bertrand, Judith|Ghogha, Atefeh|Luangrath, Vilayphone|Bedford, Fiona K|Lamarche-Vane, Nathalie
PMID: 21849478
Journal: Mol Cancer. 2011 Sep 23;10:118.
Title: BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
Author: Makrodouli, Eleni|Oikonomou, Eftychia|Koc, Michal|Andera, Ladislav|Sasazuki, Takehiko|Shirasawa, Senji|Pintzas, Alexander
PMID: 21943101
Journal: Eur J Pharmacol. 2011 Dec 5;671(1-3):7-17.
Title: Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA-Rock and Src-FAK signalling in colon cancer cells.
Author: Leve, Fernanda|Marcondes, Taline Guimaraes Correa|Bastos, Lilian Goncalves R|Rabello, Sarah Vieira|Tanaka, Marcelo Neves|Morgado-Diaz, Jose Andres
PMID: 21968138
Journal: Int J Clin Oncol. 2012 Apr;17(2):137-42.
Title: Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.
Author: Fujita, Akihiko|Shida, Atsuo|Fujioka, Shuichi|Kurihara, Hideaki|Okamoto, Tomoyoshi|Yanaga, Katsuhiko
PMID: 21698524
Journal: Oncogene. 2012 Aug 30;31(35):3913-23.
Title: The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.
Author: Muehlich, S|Hampl, V|Khalid, S|Singer, S|Frank, N|Breuhahn, K|Gudermann, T|Prywes, R
PMID: 22139079
Journal: PLoS One. 2012;7(2):e32204.
Title: Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signaling.
Author: Cartier-Michaud, Amandine|Malo, Michel|Charriere-Bertrand, Cecile|Gadea, Gilles|Anguille, Christelle|Supiramaniam, Ajitha|Lesne, Annick|Delaplace, Franck|Hutzler, Guillaume|Roux, Pierre|Lawrence, Daniel A|Barlovatz-Meimon, Georgia
PMID: 22363817
Journal: J Cell Biochem. 2012 Aug;113(8):2549-59.
Title: Rho GTPase signaling in the development of colorectal cancer.
Author: Leve, Fernanda|Morgado-Diaz, Jose A
PMID: 22467564
Journal: Proteomics. 2012 Jun;12(12):1928-37.
Title: Comparative label-free LC-MS/MS analysis of colorectal adenocarcinoma and metastatic cells treated with 5-fluorouracil.
Author: Bauer, Kerry M|Lambert, Paul A|Hummon, Amanda B
PMID: 22623418
Journal: PLoS One. 2012;7(5):e37830.
Title: Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins.
Author: Miller, Nichol L G|Lawson, Christine|Chen, Xiao Lei|Lim, Ssang-Taek|Schlaepfer, David D
PMID: 22649559
Journal: Cancer Lett. 2012 Dec 1;325(1):99-107.
Title: GCF2/LRRFIP1 promotes colorectal cancer metastasis and liver invasion through integrin-dependent RhoA activation.
Author: Ariake, Kyohei|Ohtsuka, Hideo|Motoi, Fuyuhiko|Douchi, Daisuke|Oikawa, Masaya|Rikiyama, Toshiki|Fukase, Koji|Katayose, Yu|Egawa, Shinichi|Unno, Michiaki
PMID: 22750095
Journal: Biochem Biophys Res Commun. 2012 Nov 23;428(3):333-8.
Title: Role of km23-1 in RhoA/actin-based cell migration.
Author: Jin, Qunyan|Pulipati, Nageswara R|Zhou, Weidong|Staub, Cory M|Liotta, Lance A|Mulder, Kathleen M
PMID: 23079622
Journal: PLoS One. 2012;7(11):e48344.
Title: Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity.
Author: de Toledo, Marion|Anguille, Christelle|Roger, Laureline|Roux, Pierre|Gadea, Gilles
PMID: 23144867
Journal: Oncogene. 2013 May 23;32(21):2649-60.
Title: Cell fusion promotes chemoresistance in metastatic colon carcinoma.
Author: Carloni, V|Mazzocca, A|Mello, T|Galli, A|Capaccioli, S
PMID: 22751128
Journal: Int J Cancer. 2013 Jul;133(1):43-57.
Title: Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.
Author: Basu Roy, Upal K|Henkhaus, Rebecca S|Loupakis, Fotios|Cremolini, Chiara|Gerner, Eugene W|Ignatenko, Natalia A
PMID: 23280667
Journal: J Proteome Res. 2013 Apr 5;12(4):1732-42.
Title: Proteogenomic analysis of human colon carcinoma cell lines LIM1215, LIM1899, and LIM2405.
Author: Fanayan, Susan|Smith, Joshua T|Lee, Ling Y|Yan, Fangfei|Snyder, Michael|Hancock, William S|Nice, Edouard
PMID: 23458625
Journal: Oncogene. 2013 Oct 10;32(41):4960-9.
Title: Enteropathogenic Escherichia coli-induced macrophage inhibitory cytokine 1 mediates cancer cell survival: an in vitro implication of infection-linked tumor dissemination.
Author: Choi, H J|Kim, J|Do, K H|Park, S-H|Moon, Y
PMID: 23503457
Journal: Mol Cell Biochem. 2013 Aug;380(1-2):107-19.
Title: MiR-126 suppresses colon cancer cell proliferation and invasion via inhibiting RhoA/ROCK signaling pathway.
Author: Li, Nan|Tang, Anliu|Huang, Shuo|Li, Zeng|Li, Xiayu|Shen, Shourong|Ma, Jian|Wang, Xiaoyan
PMID: 23615712
Journal: Int J Colorectal Dis. 2013 Nov;28(11):1479-87.
Title: CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling.
Author: Al-haidari, Amr A|Syk, Ingvar|Jirstrom, Karin|Thorlacius, Henrik
PMID: 23649168
Journal: Int J Mol Med. 2013 Jul;32(1):130-6.
Title: Inhibition of arginine ADP-ribosyltransferase 1 reduces the expression of poly(ADP-ribose) polymerase-1 in colon carcinoma.
Author: Tang, Yi|Wang, Ya-Lan|Yang, Lian|Xu, Jian-Xia|Xiong, Wei|Xiao, Ming|Li, Ming
PMID: 23652727
Journal: J Transl Med. 2013 Nov 27;11:295.
Title: Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
Author: Zins, Karin|Gunawardhana, Sandun|Lucas, Trevor|Abraham, Dietmar|Aharinejad, Seyedhossein
PMID: 24279335
Journal: PLoS One. 2013 Dec 30;8(12):e83629.
Title: Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.
Author: Kagawa, Yoshinori|Matsumoto, Shinji|Kamioka, Yuji|Mimori, Koshi|Naito, Yoko|Ishii, Taeko|Okuzaki, Daisuke|Nishida, Naohiro|Maeda, Sakae|Naito, Atsushi|Kikuta, Junichi|Nishikawa, Keizo|Nishimura, Junichi|Haraguchi, Naotsugu|Takemasa, Ichiro|Mizushima, Tsun
PMID: 24386239
Journal: Oncogene. 2014 Apr 17;33(16):2123-33.
Title: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author: Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J
PMID: 23644655
Journal: J Mol Neurosci. 2014 Mar;52(3):323-30.
Title: Piezoelectric ceramic (PZT) modulates axonal guidance growth of rat cortical neurons via RhoA, Rac1, and Cdc42 pathways.
Author: Wen, Jianqiang|Liu, Meili
PMID: 24203571
Journal: J Cell Sci. 2014 Feb 1;127(Pt 3):497-508.
Title: PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity.
Author: Espejo, Rosario|Jeng, Yowjiun|Paulucci-Holthauzen, Adriana|Rengifo-Cam, William|Honkus, Krysta|Anastasiadis, Panos Z|Sastry, Sarita K
PMID: 24284071
Journal: Biochem Biophys Res Commun. 2014 Mar 28;446(1):68-72.
Title: HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.
Author: Al-Haidari, Amr A|Syk, Ingvar|Thorlacius, Henrik
PMID: 24582560
Journal: Br J Cancer. 2014 Apr 29;110(9):2310-20.
Title: TAp63 suppress metastasis via miR-133b in colon cancer cells.
Author: Lin, C W|Li, X R|Zhang, Y|Hu, G|Guo, Y H|Zhou, J Y|Du, J|Lv, L|Gao, K|Zhang, Y|Deng, H
PMID: 24594999
Journal: BMC Cancer. 2014 Mar 19;14:208.
Title: Increased diacylglycerol kinase zeta expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.
Author: Cai, Kun|Mulatz, Kirk|Ard, Ryan|Nguyen, Thanh|Gee, Stephen H
PMID: 24646293
Journal: Oncol Rep. 2014 May;31(5):2335-43.
Title: Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Author: Kuang, Jing|Wang, Ya-Lan|Xiao, Ming|Tang, Yi|Chen, Wen-Wen|Song, Guang-Lin|Yang, Xi|Li, Ming
PMID: 24676941
Journal: Mol Pharmacol. 2014 Sep;86(3):252-62.
Title: Galpha13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.
Author: Patel, Maulik|Kawano, Takeharu|Suzuki, Nobuchika|Hamakubo, Takao|Karginov, Andrei V|Kozasa, Tohru
PMID: 24958816
Journal: Oncotarget. 2014 Nov 15;5(21):10778-90.
Title: Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.
Author: Tang, Jianjun|Wang, Gang|Zhang, Meifang|Li, Feng-yan|Sang, Yi|Wang, Boqing|Hu, Kaishun|Wu, Yuanzhong|Luo, Rongzhen|Liao, Dan|Cao, Jingying|Wang, Xin|Wang, Li|Zhang, Ruhua|Zhang, Xiaoshi|Deng, Wu-guo|Xie, Dan|Xu, Rui-hua|Kang, Tiebang
PMID: 25360999
Journal: Nat Commun. 2014 Nov 21;5:5458.
Title: RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.
Author: Rodrigues, Paulo|Macaya, Irati|Bazzocco, Sarah|Mazzolini, Rocco|Andretta, Elena|Dopeso, Higinio|Mateo-Lozano, Silvia|Bilic, Josipa|Carton-Garcia, Fernando|Nieto, Rocio|Suarez-Lopez, Lucia|Afonso, Elsa|Landolfi, Stefania|Hernandez-Losa, Javier|Kobayashi, K
PMID: 25413277
Journal: Oncogene. 2015 Jun;34(26):3441-51.
Title: A novel role for Plk4 in regulating cell spreading and motility.
Author: Rosario, C O|Kazazian, K|Zih, F S W|Brashavitskaya, O|Haffani, Y|Xu, R S Z|George, A|Dennis, J W|Swallow, C J
PMID: 25174401
Journal: J Biol Chem. 2015 Jun 12;290(24):15197-209.
Title: Gastrin-stimulated Galpha13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.
Author: Masia-Balague, Miriam|Izquierdo, Ismael|Garrido, Georgina|Cordomi, Arnau|Perez-Benito, Laura|Miller, Nichol L G|Schlaepfer, David D|Gigoux, Veronique|Aragay, Anna M
PMID: 25922072
Journal: Cancer Sci. 2015 Oct;106(10):1385-93.
Title: Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer.
Author: Zeng, Yuanfeng|Xie, Huijun|Qiao, Yudan|Wang, Jianmei|Zhu, Xiling|He, Guoyang|Li, Yuling|Ren, Xiaoli|Wang, Feifei|Liang, Li|Ding, Yanqing
PMID: 26258642
Journal: Int J Clin Exp Pathol. 2015 Jun 1;8(6):7040-4. eCollection 2015.
Title: Effect of shRNA targeted against RhoA on proliferation and migration of human colonic cancer cells.
Author: Wang, Man|Wang, Xiu-Jie|Liu, Bing-Rong
PMID: 26261596
Journal: Mol Pharmacol. 2015 Nov;88(5):880.
Title: Correction to "Galpha(1)(3)/PDZ-RhoGEF/RhoA Signaling Is Essential for Gastrin-Releasing Peptide Receptor-Mediated Colon Cancer Cell Migration".
Author:
PMID: 26450926
Journal: Autophagy. 2015;11(12):2309-22.
Title: Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.
Author: Wei, Fu-Zheng|Cao, Ziyang|Wang, Xi|Wang, Hui|Cai, Mu-Yan|Li, Tingting|Hattori, Naoko|Wang, Donglai|Du, Yipeng|Song, Boyan|Cao, Lin-Lin|Shen, Changchun|Wang, Lina|Wang, Haiying|Yang, Yang|Xie, Dan|Wang, Fan|Ushijima, Toshikazu|Zhao, Ying|Zhu, Wei-Guo
PMID: 26735435
Journal: Int J Oncol. 2016 Feb;48(2):714-22.
Title: RhoA is associated with invasion and poor prognosis in colorectal cancer.
Author: Jeong, Dongjun|Park, Soyoung|Kim, Hyungjoo|Kim, Chang-Jin|Ahn, Tae Sung|Bae, Sang Byung|Kim, Han Jo|Kim, Tae Hyun|Im, Jungkyun|Lee, Moon Soo|Kwon, Hyog Young|Baek, Moo Jun
PMID: 26648547
Journal: Mol Cancer Res. 2016 Mar;14(3):267-77.
Title: Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1.
Author: Kent, Oliver A|Mendell, Joshua T|Rottapel, Robert
PMID: 26747707
Journal: Biol Cell. 2016 May;108(5):115-26.
Title: Direct measurement of oscillatory RhoA activity in embryonic cortical neurons stimulated with the axon guidance cue netrin-1 using fluorescence resonance energy transfer.
Author: Antoine-Bertrand, Judith|Fu, Min|Lamarche-Vane, Nathalie
PMID: 26787017
Journal: Front Med. 2016 Jun;10(2):178-82.
Title: Bioinformatic exploration of MTA1-regulated gene networks in colon cancer.
Author: Li, Chunxiao|Wang, Haijuan|Lin, Feng|Li, Hui|Wen, Tao|Qian, Haili|Zhan, Qimin
PMID: 27052252
Journal: BMC Cancer. 2016 May 31;16:341.
Title: Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer.
Author: Eriksson, Oskar|Thulin, Asa|Asplund, Anna|Hegde, Geeta|Navani, Sanjay|Siegbahn, Agneta
PMID: 27246245
Journal: Eur Rev Med Pharmacol Sci. 2016 May;20(10):2028-37.
Title: Upregulated STAT3 and RhoA signaling in colorectal cancer (CRC) regulate the invasion and migration of CRC cells.
Author: Zhang, G-Y|Yang, W-H|Chen, Z
PMID: 27249601
Journal: Int J Oncol. 2016 Aug;49(2):646-56.
Title: Regulation of the RhoA/ROCK/AKT/beta-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma.
Author: Song, Guang-Lin|Jin, Cong-Cong|Zhao, Wei|Tang, Yi|Wang, Ya-Lan|Li, Ming|Xiao, Ming|Li, Xian|Li, Qing-Shu|Lin, Xiao|Chen, Wen-Wen|Kuang, Jing
PMID: 27277835
Journal: Tumour Biol. 2016 Sep;37(9):12477-12483.
Title: Epigenetic silencing of TPM2 contributes to colorectal cancer progression upon RhoA activation.
Author: Cui, Ji|Cai, Yonghua|Hu, Ying|Huang, Zenghong|Luo, Yanxin|Kaz, Andrew M|Yang, Zihuan|Chen, Dianke|Fan, Xinjuan|Grady, William M|Wang, Jianping
PMID: 27333992
Journal: Mol Med Rep. 2016 Sep;14(3):2534-40.
Title: alpha-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling.
Author: Yao, Jialin|Gao, Peng|Xu, Yang|Li, Zhaozhu
PMID: 27432222
Journal: Oncotarget. 2016 Sep 13;7(37):60230-60244.
Title: MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway.
Author: Yuan, Wei|Guo, Ye-Qing|Li, Xia-Yu|Deng, Min-Zi|Shen, Zhao-Hua|Bo, Chi-Bin|Dai, Ya-Fei|Huang, Ming-Yu|Yang, Zhen-Yu|Quan, Yong-Sheng|Tian, Li|Wang, Xiaoyan
PMID: 27517626
Journal: Oncotarget. 2016 Nov 8;7(45):72908-72922.
Title: Genomic characterization of liver metastases from colorectal cancer patients.
Author: Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant
PMID: 27662660
Journal: Biochem Biophys Res Commun. 2016 Nov 4;480(1):48-54.
Title: Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis.
Author: Yu, Haitao|Jin, Sufeng|Zhang, Na|Xu, Qi
PMID: 27720713
Journal: Oncotarget. 2016 Dec 27;7(52):87136-87146.
Title: RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer.
Author: Ruihua, Huang|Mengyi, Zhang|Chong, Zhao|Meng, Qiu|Xin, Ma|Qiulin, Tang|Feng, Bi|Ming, Liu
PMID: 27888624
Journal: Oncotarget. 2016 Dec 27;7(52):87147-87160.
Title: Negative feedback between TAp63 and Mir-133b mediates colorectal cancer suppression.
Author: Dai, Jing|Wu, Hao|Zhang, Yi|Gao, Kai|Hu, Gui|Guo, Yihang|Lin, Changwei|Li, Xiaorong
PMID: 27894087
Journal: Cell Mol Biol (Noisy-le-grand). 2016 Oct 31;62(12):91-96.
Title: Vincristine promotes migration and invasion of colorectal cancer HCT116 cells through RhoA/ROCK/ Myosin light chain pathway.
Author: Jin, X|Liu, K|Jiao, B|Wang, X|Huang, S|Ren, W|Zhao, K
PMID: 27894406
Journal: Cell Mol Gastroenterol Hepatol. 2015 Nov 14;2(1):11-21.
Title: New and Unexpected Biological Functions for the Src-Homology 2 Domain-Containing Phosphatase SHP-2 in the Gastrointestinal Tract.
Author: Coulombe, Genevieve|Rivard, Nathalie
PMID: 28174704
Journal: Neoplasma. 2017;64(1):32-39.
Title: Expression of orphan GPR56 correlates with tumor progression in human epithelial ovarian cancer.
Author: Liu, Z|Huang, Z|Yang, W|Li, Z|Xing, S|Li, H|Hu, B|Li, P
PMID: 27881002
Journal: Mol Med Rep. 2017 Mar;15(3):1222-1228.
Title: Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo.
Author: Xu, Jian-Xia|Xiong, Wei|Zeng, Zhen|Tang, Yi|Wang, Ya-Lan|Xiao, Ming|Li, Ming|Li, Qing Shu|Song, Guang-Lin|Kuang, Jing
PMID: 28138708
Journal: Oncotarget. 2017 Feb 28;8(9):14887-14896.
Title: MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA.
Author: Al-Haidari, Amr A|Syk, Ingvar|Thorlacius, Henrik
PMID: 28146427
Journal: Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1246-1259.
Title: A crosstalk between muscarinic and CRF2 receptors regulates cellular adhesion properties of human colon cancer cells.
Author: Pelissier-Rota, M|Chartier, N T|Bonaz, B|Jacquier-Sarlin, M R
PMID: 28432022
Journal: J Am Heart Assoc. 2017 May 19;6(5). pii: JAHA.116.005198.
Title: Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats.
Author: Xie, Zongyi|Enkhjargal, Budbazar|Reis, Cesar|Huang, Lei|Wan, Weifeng|Tang, Jiping|Cheng, Yuan|Zhang, John H
PMID: 28526701
Journal: BMC Genomics. 2017 May 30;18(1):421.
Title: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author: Cong, Wang|Meng, Xianglian|Li, Jin|Zhang, Qiushi|Chen, Feng|Liu, Wenjie|Wang, Ying|Cheng, Sipu|Yao, Xiaohui|Yan, Jingwen|Kim, Sungeun|Saykin, Andrew J|Liang, Hong|Shen, Li
PMID: 28558704
Journal: Oncotarget. 2017 Jul 4;8(27):44498-44510.
Title: Cell type-dependent HIF1 alpha-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells.
Author: Tatrai, Eniko|Bartal, Alexandra|Gacs, Alexandra|Paku, Sandor|Kenessey, Istvan|Garay, Tamas|Hegedus, Balazs|Molnar, Eszter|Cserepes, Mihaly T|Hegedus, Zita|Kucsma, Nora|Szakacs, Gergely|Tovari, Jozsef
PMID: 28562340
Journal: J Ethnopharmacol. 2017 Sep 14;209:305-316.
Title: Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway.
Author: Lin, Yin-Yin|Lee, I-Yun|Huang, Wen-Shih|Lin, Yu-Shin|Kuan, Feng-Che|Shu, Li-Hsin|Cheng, Yu-Ching|Yang, Yao-Hsu|Wu, Ching-Yuan
PMID: 28807849
Journal: Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2283-2296.
Title: The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment.
Author: Ciszewski, Wojciech M|Sobierajska, Katarzyna|Wawro, Marta E|Klopocka, Wanda|Chefczynska, Natasza|Muzyczuk, Angelika|Siekacz, Kamil|Wujkowska, Agata|Niewiarowska, Jolanta
PMID: 28893556
Journal: Oncotarget. 2017 May 15;8(34):56659-56671.
Title: PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition.
Author: Islam, Salman Ul|Shehzad, Adeeb|Sonn, Jong Kyung|Lee, Young Sup
PMID: 28915620
Journal: Oncotarget. 2017 Jul 25;8(38):63764-63779.
Title: miR-223 promotes colon cancer by directly targeting p120 catenin.
Author: Liu, Liwei|Zhang, Chao|Li, Xiyu|Sun, Wenjia|Qin, Shenghui|Qin, Lingzhi|Wang, Xi
PMID: 28969027
Journal: Nat Commun. 2017 Nov 28;8(1):1834.
Title: Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells.
Author: Ito, Shoko|Okuda, Satoru|Abe, Masako|Fujimoto, Mari|Onuki, Tetsuo|Nishimura, Tamako|Takeichi, Masatoshi
PMID: 29184140
Journal: Oncotarget. 2017 Nov 30;8(65):109632-109645.
Title: LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.
Author: Yao, Qian|An, Yu|Hou, Wei|Cao, Ya-Nan|Yao, Meng-Fei|Ma, Ning-Ning|Hou, Lin|Zhang, Hong|Liu, Hai-Jing|Zhang, Bo
PMID: 29312635
Journal: Oncol Res. 2018 Mar 5;26(2):209-217.
Title: Procaine Inhibits the Proliferation and Migration of Colon Cancer Cells Through Inactivation of the ERK/MAPK/FAK Pathways by Regulation of RhoA.
Author: Li, Chang|Gao, Shuohui|Li, Xiaoping|Li, Chang|Ma, Lianjun
PMID: 28492141
Journal: Rev Physiol Biochem Pharmacol. 2018;174:1-23.
Title: Ezrin Orchestrates Signal Transduction in Airway Cells.
Author: Yin, Lei-Miao|Duan, Ting-Ting|Ulloa, Luis|Yang, Yong-Qing
PMID: 28702704
Journal: Cancer Sci. 2018 Jan;109(1):84-93.
Title: Rac GTPase activating protein 1 promotes oncogenic progression of epithelial ovarian cancer.
Author: Wang, Chuanjiang|Wang, Wenxia|Liu, Yujuan|Yong, Min|Yang, Yamei|Zhou, Honggui
PMID: 29095547
Journal: Br J Cancer. 2018 Jan;118(1):106-116.
Title: Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.
Author: Dopeso, Higinio|Rodrigues, Paulo|Bilic, Josipa|Bazzocco, Sarah|Carton-Garcia, Fernando|Macaya, Irati|de Marcondes, Priscila Guimaraes|Anguita, Estefania|Masanas, Marc|Jimenez-Flores, Lizbeth M|Martinez-Barriocanal, Agueda|Nieto, Rocio|Segura, Miguel F|Sch
PMID: 29206819
Journal: Nat Commun. 2018 Jan 17;9(1):254.
Title: 133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.
Author: Campbell, Hamish|Fleming, Nicholas|Roth, Imogen|Mehta, Sunali|Wiles, Anna|Williams, Gail|Vennin, Claire|Arsic, Nikola|Parkin, Ashleigh|Pajic, Marina|Munro, Fran|McNoe, Les|Black, Michael|McCall, John|Slatter, Tania L|Timpson, Paul|Reddel, Roger|Roux, Pier
PMID: 29343721
Journal: J Biomed Mater Res A. 2018 Jun;106(6):1500-1510.
Title: Carboxylated graphene oxide promoted axonal guidance growth by activating Netrin-1/deleted in colorectal cancer signaling in rat primary cultured cortical neurons.
Author: Liu, Meili|Jia, Zhengtai|Xiao, Xiongfu|Zhang, Zhifa|Li, Ping|Zhou, Gang|Fan, Yubo
PMID: 29377591
Journal: Biochem Pharmacol. 2018 Apr;150:191-201.
Title: Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.
Author: Li, Mingyue|Yue, Grace Gar-Lee|Song, Li-Hua|Huang, Mao-Bo|Lee, Julia Kin-Ming|Tsui, Stephen Kwok-Wing|Fung, Kwok-Pui|Tan, Ning-Hua|Lau, Clara Bik-San
PMID: 29454618
Journal: Gastroenterology. 2018 Jun;154(8):2209-2221.e14.
Title: P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Author: Dou, Changwei|Liu, Zhikui|Tu, Kangsheng|Zhang, Hongbin|Chen, Chen|Yaqoob, Usman|Wang, Yuanguo|Wen, Jialing|van Deursen, Jan|Sicard, Delphine|Tschumperlin, Daniel|Zou, Hongzhi|Huang, Wei-Chien|Urrutia, Raul|Shah, Vijay H|Kang, Ningling
PMID: 29454793
Journal: Cell Commun Adhes. 2018 Dec;24(1):1-10.
Title: Kruppel-like factor 4 mediates cellular migration and invasion by altering RhoA activity.
Author: Brauer, Philip R|Kim, Jee Hun|Ochoa, Humberto J|Stratton, Elizabeth R|Black, Kathryn M|Rosencrans, William|Stacey, Eliza|Hagos, Engda G
PMID: 29498307
Journal: Cell Physiol Biochem. 2018;47(1):368-377.
Title: The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells.
Author: Zacharopoulou, Nefeli|Tsapara, Anna|Kallergi, Galatea|Schmid, Evi|Alkahtani, Saad|Alarifi, Saud|Tsichlis, Philip N|Kampranis, Sotirios C|Stournaras, Christos
PMID: 29772566
Journal: Exp Cell Res. 2018 Aug 1;369(1):158-165.
Title: PRP4 kinase induces actin rearrangement and epithelial-mesenchymal transition through modulation of the actin-binding protein cofilin.
Author: Islam, Salman Ul|Ahmed, Muhammad Bilal|Lee, Su Jin|Shehzad, Adeeb|Sonn, Jong Kyung|Kwon, Oh-Shin|Lee, Young Sup
PMID: 29787735
Journal: NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title: Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author: Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling
PMID: 29872721
Journal: Biochim Biophys Acta Mol Cell Res. 2018 Oct 5. pii: S0167-4889(18)30429-4.
Title: Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells.
Author: Sousa-Squiavinato, Annie Cristhine Moraes|Rocha, Murilo Ramos|Barcellos-de-Souza, Pedro|Souza, Waldemir Fernandes|Morgado-Diaz, Jose Andres
PMID: 30296500