Primary Site >> Liver Cancer
Gene >> RET
| 1. | |||||||||||
| Journal: | Curr Drug Targets. 2001 Mar;2(1):41-55. | ||||||||||
| Title: | Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene. | ||||||||||
| Author: | Longati, P|Comoglio, P M|Bardelli, A | ||||||||||
| PMID: | 11465538 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2006 Dec 15;66(24):11851-8. | ||||||||||
| Title: | Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. | ||||||||||
| Author: | Liu, Li|Cao, Yichen|Chen, Charles|Zhang, Xiaomei|McNabola, Angela|Wilkie, Dean|Wilhelm, Scott|Lynch, Mark|Carter, Christopher | ||||||||||
| PMID: | 17178882 | ||||||||||
| 3. | |||||||||||
| Journal: | Eur J Med Res. 2011 Nov 10;16(11):491-4. | ||||||||||
| Title: | Sunitinib induced pyoderma gangrenosum-like ulcerations. | ||||||||||
| Author: | Akanay-Diesel, S|Hoff, N P|Kurle, S|Haes, J|Erhardt, A|Haussinger, D|Schulte, K-W|Bolke, Edwin|Matuschek, C|Budach, W|Gerber, P A|Homey, B | ||||||||||
| PMID: | 22027642 | ||||||||||
| 4. | |||||||||||
| Journal: | Exp Ther Med. 2011 May;2(3):399-403. | ||||||||||
| Title: | Use of protein array technology to investigate receptor tyrosine kinases activated in hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Shi|Gong, Jian|Morishita, Asahiro|Nomura, Takako|Miyoshi, Hisaaki|Tani, Joji|Kato, Kiyohito|Yoneyama, Hirohito|Deguchi, Akihiro|Mori, Hirohito|Mimura, Shima|Nomura, Kei|Himoto, Takashi|Deguchi, Kazushi|Okano, Keiichi|Izuishi, Kunihiko|Suzuki, Yasuyuk | ||||||||||
| PMID: | 22977516 | ||||||||||
| 5. | |||||||||||
| Journal: | Curr Med Chem. 2012;19(7):938-44. | ||||||||||
| Title: | Sorafenib (BAY 43-9006) in hepatocellular carcinoma patients: from discovery to clinical development. | ||||||||||
| Author: | Ranieri, G|Gadaleta-Caldarola, G|Goffredo, V|Patruno, R|Mangia, A|Rizzo, A|Sciorsci, R L|Gadaleta, C D | ||||||||||
| PMID: | 22214462 | ||||||||||
| 6. | |||||||||||
| Journal: | J Nucl Med. 2012 Sep;53(9):1352-8. | ||||||||||
| Title: | Correlation of the genotype of paragangliomas and pheochromocytomas with their metabolic phenotype on 3,4-dihydroxy-6-18F-fluoro-L-phenylalanin PET. | ||||||||||
| Author: | Rischke, H Christian|Benz, Matthias R|Wild, Damian|Mix, Michael|Dumont, Rebecca A|Campbell, Dean|Seufert, Jochen|Wiech, Thorsten|Rossler, Jochen|Weber, Wolfgang A|Neumann, Hartmut P H | ||||||||||
| PMID: | 22836345 | ||||||||||
| 7. | |||||||||||
| Journal: | Invest New Drugs. 2013 Aug;31(4):1078-86. | ||||||||||
| Title: | Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis. | ||||||||||
| Author: | Belum, Viswanath Reddy|Wu, Shenhong|Lacouture, Mario E | ||||||||||
| PMID: | 23700287 | ||||||||||
| 8. | |||||||||||
| Journal: | J Magn Reson Imaging. 2013 Sep;38(3):548-54. | ||||||||||
| Title: | Timing of the hepatic arterial phase at Gd-EOB-DTPA-enhanced hepatic dynamic MRI: comparison of the test-injection and the fixed-time delay method. | ||||||||||
| Author: | Nakamura, Shinichi|Nakaura, Takeshi|Kidoh, Masafumi|Utsunomiya, Daisuke|Doi, Yasuro|Harada, Kazunori|Uemura, Shozaburou|Yamashita, Yasuyuki | ||||||||||
| PMID: | 23744782 | ||||||||||
| 9. | |||||||||||
| Journal: | BioDrugs. 2013 Dec;27(6):615-28. | ||||||||||
| Title: | Sorafenib and thyroid cancer. | ||||||||||
| Author: | Fallahi, Poupak|Ferrari, Silvia Martina|Santini, Francesca|Corrado, Alda|Materazzi, Gabriele|Ulisse, Salvatore|Miccoli, Paolo|Antonelli, Alessandro | ||||||||||
| PMID: | 23818056 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2013 Dec;72(6):1183-93. | ||||||||||
| Title: | Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis. | ||||||||||
| Author: | Bousquet, Guilhem|Varna, Mariana|Ferreira, Irmine|Wang, Li|Mongiat-Artus, Pierre|Leboeuf, Christophe|de Bazelaire, Cedric|Faivre, Sandrine|Bertheau, Philippe|Raymond, Eric|Germain, Stephane|Janin, Anne | ||||||||||
| PMID: | 24061866 | ||||||||||
| 11. | |||||||||||
| Journal: | J Carcinog. 2013 Dec 31;12:22. | ||||||||||
| Title: | Targeted therapies in development for non-small cell lung cancer. | ||||||||||
| Author: | Reungwetwattana, Thanyanan|Dy, Grace Kho | ||||||||||
| PMID: | 24574860 | ||||||||||
| 12. | |||||||||||
| Journal: | Recent Results Cancer Res. 2014;201:185-96. | ||||||||||
| Title: | Regorafenib. | ||||||||||
| Author: | Ettrich, Thomas J|Seufferlein, Thomas | ||||||||||
| PMID: | 24756792 | ||||||||||
| 13. | |||||||||||
| Journal: | PLoS One. 2014 May 5;9(5):e96799. | ||||||||||
| Title: | Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases. | ||||||||||
| Author: | Medina-Echeverz, Jose|Fioravanti, Jessica|Diaz-Valdes, Nancy|Frank, Kathrin|Aranda, Fernando|Gomar, Celia|Ardaiz, Nuria|Dotor, Javier|Umansky, Viktor|Prieto, Jesus|Berraondo, Pedro | ||||||||||
| PMID: | 24797128 | ||||||||||
| 14. | |||||||||||
| Journal: | Vasc Cell. 2014 Sep 6;6:18. | ||||||||||
| Title: | Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage. | ||||||||||
| Author: | Yamamoto, Yuji|Matsui, Junji|Matsushima, Tomohiro|Obaishi, Hiroshi|Miyazaki, Kazuki|Nakamura, Katsuji|Tohyama, Osamu|Semba, Taro|Yamaguchi, Atsumi|Hoshi, Sachi Suzuki|Mimura, Fusayo|Haneda, Toru|Fukuda, Yoshio|Kamata, Jun-Ichi|Takahashi, Keiko|Matsukura, | ||||||||||
| PMID: | 25197551 | ||||||||||
| 15. | |||||||||||
| Journal: | Onco Targets Ther. 2015 Dec 8;8:3691-701. | ||||||||||
| Title: | Profile of nintedanib in the treatment of solid tumors: the evidence to date. | ||||||||||
| Author: | Awasthi, Niranjan|Schwarz, Roderich E | ||||||||||
| PMID: | 26677336 | ||||||||||
| 16. | |||||||||||
| Journal: | Anticancer Drugs. 2015 Oct;26(9):1004-7. | ||||||||||
| Title: | A significant response to sorafenib in a woman with advanced lung adenocarcinoma and a BRAF non-V600 mutation. | ||||||||||
| Author: | Sereno, Maria|Moreno, Victor|Moreno Rubio, Juan|Gomez-Raposo, Cesar|Garcia Sanchez, Sagrario|Hernandez Jusdado, Rebeca|Falagan, Sandra|Zambrana Tebar, Francisco|Casado Saenz, Enrique | ||||||||||
| PMID: | 26237499 | ||||||||||
| 17. | |||||||||||
| Journal: | J Nucl Med. 2015 Jun;56(6):839-46. | ||||||||||
| Title: | Semiquantitative 123I-Metaiodobenzylguanidine Scintigraphy to Distinguish Pheochromocytoma and Paraganglioma from Physiologic Adrenal Uptake and Its Correlation with Genotype-Dependent Expression of Catecholamine Transporters. | ||||||||||
| Author: | van Berkel, Anouk|Rao, Jyotsna U|Lenders, Jacques W M|Pellegata, Natalia S|Kusters, Benno|Piscaer, Ianthe|Hermus, Ad R M M|Plantinga, Theo S|Langenhuijsen, Johan F|Vriens, Dennis|Janssen, Marcel J R|Gotthardt, Martin|Timmers, Henri J L M | ||||||||||
| PMID: | 25883126 | ||||||||||
| 18. | |||||||||||
| Journal: | Drugs. 2015 Apr;75(5):553-60. | ||||||||||
| Title: | Lenvatinib: first global approval. | ||||||||||
| Author: | Scott, Lesley J | ||||||||||
| PMID: | 25795101 | ||||||||||
| 19. | |||||||||||
| Journal: | Tumour Biol. 2015 Mar;36(3):1511-8. | ||||||||||
| Title: | Overexpression of miR-218 inhibits hepatocellular carcinoma cell growth through RET. | ||||||||||
| Author: | Sui, Chengjun|Xu, Feng|Shen, Weifeng|Geng, Li|Xie, Feng|Dai, Binghua|Lu, Jiongjiong|Zhang, Minfeng|Yang, Jiamei | ||||||||||
| PMID: | 25374061 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 14;7(24):36829-36841. | ||||||||||
| Title: | GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis. | ||||||||||
| Author: | Zhong, Zhaohui|Gu, Huiying|Peng, Jirun|Wang, Wenzheng|Johnstone, Brian H|March, Keith L|Farlow, Martin R|Du, Yansheng | ||||||||||
| PMID: | 27167204 | ||||||||||
| 21. | |||||||||||
| Journal: | J Gastroenterol. 2017 Apr;52(4):512-519. | ||||||||||
| Title: | Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma. | ||||||||||
| Author: | Ikeda, Kenji|Kudo, Masatoshi|Kawazoe, Seiji|Osaki, Yukio|Ikeda, Masafumi|Okusaka, Takuji|Tamai, Toshiyuki|Suzuki, Takuya|Hisai, Takashi|Hayato, Seiichi|Okita, Kiwamu|Kumada, Hiromitsu | ||||||||||
| PMID: | 27704266 | ||||||||||
| 22. | |||||||||||
| Journal: | Theranostics. 2017 Jan 1;7(1):164-179. | ||||||||||
| Title: | Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Da|Zheng, Aixian|Li, Juan|Wu, Ming|Wu, Lingjie|Wei, Zuwu|Liao, Naishun|Zhang, Xiaolong|Cai, Zhixiong|Yang, Huanghao|Liu, Gang|Liu, Xiaolong|Liu, Jingfeng | ||||||||||
| PMID: | 28042325 | ||||||||||
| 23. | |||||||||||
| Journal: | Eur J Drug Metab Pharmacokinet. 2017 Dec;42(6):903-914. | ||||||||||
| Title: | Clinical Pharmacokinetic and Pharmacodynamic Profile of Lenvatinib, an Orally Active, Small-Molecule, Multitargeted Tyrosine Kinase Inhibitor. | ||||||||||
| Author: | Hussein, Ziad|Mizuo, Hitoshi|Hayato, Seiichi|Namiki, Masayuki|Shumaker, Robert | ||||||||||
| PMID: | 28236116 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncol Rep. 2017 Apr;37(4):2215-2226. | ||||||||||
| Title: | TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma. | ||||||||||
| Author: | Ye, Song|Zhao, Xin-Yi|Hu, Xiao-Ge|Li, Tang|Xu, Qiu-Ran|Yang, Huan-Ming|Huang, Dong-Sheng|Yang, Liu | ||||||||||
| PMID: | 28350084 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 18;8(16):26434-26447. | ||||||||||
| Title: | RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Wei|Jia, Wei-Dong|Hu, Bing|Pan, Yue-Yin | ||||||||||
| PMID: | 28460436 | ||||||||||
| 26. | |||||||||||
| Journal: | Future Oncol. 2017 Jul 13. | ||||||||||
| Title: | Cabozantinib in the treatment of hepatocellular carcinoma. | ||||||||||
| Author: | B Peters, Mary Linton|Miksad, Rebecca A | ||||||||||
| PMID: | 28703624 | ||||||||||
| 27. | |||||||||||
| Journal: | Eur J Cancer. 2017 Nov;86:296-304. | ||||||||||
| Title: | Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours. | ||||||||||
| Author: | Schoffski, Patrick|Gordon, Michael|Smith, David C|Kurzrock, Razelle|Daud, Adil|Vogelzang, Nicholas J|Lee, Yihua|Scheffold, Christian|Shapiro, Geoffrey I | ||||||||||
| PMID: | 29059635 | ||||||||||
| 28. | |||||||||||
| Journal: | Eur J Nucl Med Mol Imaging. 2018 Feb;45(2):278-282. | ||||||||||
| Title: | Quantitative (18)F-DOPA PET/CT in pheochromocytoma: the relationship between tumor secretion and its biochemical phenotype. | ||||||||||
| Author: | Amodru, Vincent|Guerin, Carole|Delcourt, Sarkis|Romanet, Pauline|Loundou, Anderson|Viana, Bruna|Brue, Thierry|Castinetti, Frederic|Sebag, Frederic|Pacak, Karel|Taieb, David | ||||||||||
| PMID: | 28918451 | ||||||||||
| 29. | |||||||||||
| Journal: | Lancet. 2018 Mar 24;391(10126):1163-1173. | ||||||||||
| Title: | Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial. | ||||||||||
| Author: | Kudo, Masatoshi|Finn, Richard S|Qin, Shukui|Han, Kwang-Hyub|Ikeda, Kenji|Piscaglia, Fabio|Baron, Ari|Park, Joong-Won|Han, Guohong|Jassem, Jacek|Blanc, Jean Frederic|Vogel, Arndt|Komov, Dmitry|Evans, T R Jeffry|Lopez, Carlos|Dutcus, Corina|Guo, Matthew|Sai | ||||||||||
| PMID: | 29433850 | ||||||||||
| 30. | |||||||||||
| Journal: | Recent Results Cancer Res. 2018;211:45-56. | ||||||||||
| Title: | Regorafenib. | ||||||||||
| Author: | Ettrich, Thomas J|Seufferlein, Thomas | ||||||||||
| PMID: | 30069758 | ||||||||||
| 31. | |||||||||||
| Journal: | Recent Results Cancer Res. 2018;211:187-198. | ||||||||||
| Title: | Lenvantinib: A Tyrosine Kinase Inhibitor of VEGFR 1-3, FGFR 1-4, PDGFRalpha, KIT and RET. | ||||||||||
| Author: | Zschabitz, Stefanie|Grullich, Carsten | ||||||||||
| PMID: | 30069768 | ||||||||||
| 32. | |||||||||||
| Journal: | Expert Rev Anticancer Ther. 2018 Sep 15:1-8. | ||||||||||
| Title: | Lenvatinib as a therapy for unresectable hepatocellular carcinoma. | ||||||||||
| Author: | Spallanzani, Andrea|Orsi, Giulia|Andrikou, Kalliopi|Gelsomino, Fabio|Rimini, Margherita|Riggi, Laura|Cascinu, Stefano | ||||||||||
| PMID: | 30220234 | ||||||||||