Primary Site >> Liver Cancer

Gene >> RET

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Ref: Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene.
PMID: 11465538
Ref: Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
PMID: 17178882
Ref: Sunitinib induced pyoderma gangrenosum-like ulcerations.
PMID: 22027642
Ref: Use of protein array technology to investigate receptor tyrosine kinases activated in hepatocellular carcinoma.
PMID: 22977516
Ref: Sorafenib (BAY 43-9006) in hepatocellular carcinoma patients: from discovery to clinical development.
PMID: 22214462
Ref: Correlation of the genotype of paragangliomas and pheochromocytomas with their metabolic phenotype on 3,4-dihydroxy-6-18F-fluoro-L-phenylalanin PET.
PMID: 22836345
Ref: Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis.
PMID: 23700287
Ref: Timing of the hepatic arterial phase at Gd-EOB-DTPA-enhanced hepatic dynamic MRI: comparison of the test-injection and the fixed-time delay method.
PMID: 23744782
Ref: Sorafenib and thyroid cancer.
PMID: 23818056
Ref: Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis.
PMID: 24061866
Ref: Targeted therapies in development for non-small cell lung cancer.
PMID: 24574860
Ref: Regorafenib.
PMID: 24756792
Ref: Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.
PMID: 24797128
Ref: Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage.
PMID: 25197551
Ref: Overexpression of miR-218 inhibits hepatocellular carcinoma cell growth through RET.
PMID: 25374061
Ref: Lenvatinib: first global approval.
PMID: 25795101
Ref: Semiquantitative 123I-Metaiodobenzylguanidine Scintigraphy to Distinguish Pheochromocytoma and Paraganglioma from Physiologic Adrenal Uptake and Its Correlation with Genotype-Dependent Expression of Catecholamine Transporters.
PMID: 25883126
Ref: A significant response to sorafenib in a woman with advanced lung adenocarcinoma and a BRAF non-V600 mutation.
PMID: 26237499
Ref: Profile of nintedanib in the treatment of solid tumors: the evidence to date.
PMID: 26677336
Ref: GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis.
PMID: 27167204
Ref: Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma.
PMID: 27704266
Ref: Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma.
PMID: 28042325
Ref: Clinical Pharmacokinetic and Pharmacodynamic Profile of Lenvatinib, an Orally Active, Small-Molecule, Multitargeted Tyrosine Kinase Inhibitor.
PMID: 28236116
Ref: TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma.
PMID: 28350084
Ref: RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma.
PMID: 28460436
Ref: Cabozantinib in the treatment of hepatocellular carcinoma.
PMID: 28703624
Ref: Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours.
PMID: 29059635
Ref: Quantitative (18)F-DOPA PET/CT in pheochromocytoma: the relationship between tumor secretion and its biochemical phenotype.
PMID: 28918451
Ref: Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial.
PMID: 29433850
Ref: Regorafenib.
PMID: 30069758
Ref: Lenvantinib: A Tyrosine Kinase Inhibitor of VEGFR 1-3, FGFR 1-4, PDGFRalpha, KIT and RET.
PMID: 30069768
Ref: Lenvatinib as a therapy for unresectable hepatocellular carcinoma.
PMID: 30220234