Primary Site >> Colorectal Cancer

Gene >> RELA

Journal: Biochem Pharmacol. 1994 Jan 13;47(1):145-9.
Title: The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines.
Author: Bours, V|Dejardin, E|Goujon-Letawe, F|Merville, M P|Castronovo, V
PMID: 8311838
Journal: Oncogene. 1997 Apr 3;14(13):1589-600.
Title: Down-regulation of NF-kappaB activity and NF-kappaB p65 subunit expression by ras and polyoma middle T oncogenes in human colonic Caco-2 cells.
Author: Cadoret, A|Bertrand, F|Baron-Delage, S|Levy, P|Courtois, G|Gespach, C|Capeau, J|Cherqui, G
PMID: 9129150
Journal: Cancer Lett. 1999 Sep 20;144(1):101-5.
Title: Two proteins share immunological epitopes on the tumor-associated antigen 17-1A.
Author: Chen, Y H|Yu, T|Bai, Y|Zhao, N
PMID: 10503883
Journal: Biochem J. 2000 Aug 1;349 Pt 3:765-73.
Title: Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line.
Author: Legrand-Poels, S|Schoonbroodt, S|Piette, J
PMID: 10903137
Journal: Mol Carcinog. 2000 Sep;29(1):25-36.
Title: IkappaBbeta-related proteins in normal and transformed colonic epithelial cells.
Author: Inan, M S|Place, R|Tolmacheva, V|Wang, Q S|Hubbard, A K|Rosenberg, D W|Giardina, C
PMID: 11020244
Journal: Cytobios. 2001;106 Suppl 1:43-55.
Title: Cellular protein alterations in colorectal cancer: p28, p53 and p65 studies.
Author: Stawinska, M|Brys, M|Kilianska, Z M|Hanausek-Wataszek, M|Krajewska, W M
PMID: 11534828
Journal: Zhonghua Yi Xue Za Zhi. 2002 Mar 25;82(6):384-8.
Title: [Activation of nuclear factor-kappaB and effects of anti-inflammatory treatment thereon in intestinal mucosa of patients with ulcerative colitis].
Author: Gan, Huatian|Ouyang, Qin|Chen, Youqin|Xia, Qingjie
PMID: 11953203
Journal: Gastroenterology. 2002 Oct;123(4):1163-78.
Title: PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
Author: Kim, Sunghoon|Domon-Dell, Claire|Wang, Qingding|Chung, Dai H|Di Cristofano, Antonio|Pandolfi, Pier Paolo|Freund, Jean-Noel|Evers, B Mark
PMID: 12360479
Journal: Carcinogenesis. 2002 Dec;23(12):2063-80.
Title: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author: Crowley-Weber, Cara L|Payne, Claire M|Gleason-Guzman, Mary|Watts, George S|Futscher, Bernard|Waltmire, Caroline N|Crowley, Cheray|Dvorakova, Katerina|Bernstein, Carol|Craven, Mary|Garewal, Harinder|Bernstein, Harris
PMID: 12507930
Journal: Am Surg. 2003 Jan;69(1):15-23.
Title: Antineoplastic therapy in colorectal cancer through proteasome inhibition.
Author: Hochwald, Steven N|Lind, D Scott|Malaty, John|Copeland, Edward M 3rd|Moldawer, Lyle L|MacKay, Sally L D
PMID: 12575774
Journal: Carcinogenesis. 2003 Apr;24(4):665-71.
Title: Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer.
Author: Maihofner, Christian|Charalambous, Michalis Panayiotou|Bhambra, Upinder|Lightfoot, Tracy|Geisslinger, Gerd|Gooderham, Nigel J
PMID: 12727794
Journal: Oncology. 2003;65(1):37-45.
Title: Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis.
Author: Yu, Hong-Gang|Yu, Liang-Liang|Yang, Yanning|Luo, He-Sheng|Yu, Jie-Ping|Meier, Juris J|Schrader, Henning|Bastian, Andreas|Schmidt, Wolfgang E|Schmitz, Frank
PMID: 12837981
Journal: Cancer Res. 2003 Jul 1;63(13):3632-6.
Title: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.
Author: Liu, Wenbiao|Reinmuth, Niels|Stoeltzing, Oliver|Parikh, Alexander A|Tellez, Carmen|Williams, Simon|Jung, Young D|Fan, Fan|Takeda, Akihiko|Akagi, Morihisa|Bar-Eli, Menashe|Gallick, Gary E|Ellis, Lee M
PMID: 12839952
Journal: Cell Death Differ. 2003 Sep;10(9):1078-89.
Title: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Author: Hermisson, M|Weller, M
PMID: 12934082
Journal: Br J Cancer. 2003 Oct 6;89(7):1358-65.
Title: Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells.
Author: Smartt, H J M|Elder, D J E|Hicks, D J|Williams, N A|Paraskeva, C
PMID: 14520472
Journal: J Cell Biochem. 2003 Nov 1;90(4):732-44.
Title: Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta.
Author: Chen, Fei|Wang, Muchun|O'Connor, J Patrick|He, Mai|Tripathi, Tushar|Harrison, Lawrence E
PMID: 14587029
Journal: Int J Colorectal Dis. 2004 Jan;19(1):18-22. Epub 2003 Jun 21.
Title: Increased expression of nuclear factor-kappaB/RelA is correlated with tumor angiogenesis in human colorectal cancer.
Author: Yu, Hong-Gang|Zhong, Xia|Yang, Yan-Ning|Luo, He-Sheng|Yu, Jie-Ping|Meier, Juris J|Schrader, Henning|Bastian, Andreas|Schmidt, Wolfgang E|Schmitz, Frank
PMID: 12827408
Journal: Biochem Biophys Res Commun. 2004 Feb 27;315(1):93-9.
Title: Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer.
Author: Kim, Sang-Pyo|Park, Jong-Wook|Lee, Sung-Hee|Lim, Jun Hee|Jang, Byeong-Churl|Lee, Sang-Han|Jang, In-Hwan|Freund, Jean-Noel|Suh, Seong-Il|Mun, Kyo Cheol|Song, Dae-Kyu|Ha, Eun-Mi|Lee, Won-Jae|Kwon, Taeg Kyu
PMID: 15013430
Journal: Eur J Surg Oncol. 2004 Apr;30(3):266-70.
Title: Expression of the p65 gene in patients with colorectal cancer: comparison with some histological typing, grading and clinical staging.
Author: Balcerczak, M|Balcerczak, E|Pasz-Walczak, G|Kordek, R|Mirowski, M
PMID: 15028307
Journal: Korean J Gastroenterol. 2004 Mar;43(3):176-85.
Title: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8].
Author: Lee, Dong Ki|Park, Sun Young|Baik, Soon Koo|Kwon, Sang Ok|Chung, Jun Mo|Oh, Eok-Soo|Kim, Hyun Soo
PMID: 15034288
Journal: J Biol Chem. 2004 Jun 18;279(25):26019-27. Epub 2004 Mar 26.
Title: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling.
Author: Nho, Chu Won|O'Dwyer, Peter J
PMID: 15047705
Journal: Eksp Onkol. 2004 Mar;26(1):40-7.
Title: Nuclear factor-kappa B regulates cyclooxygenase-2 expression and cell proliferation in human colorectal carcinoma tissue.
Author: Yu, Liang-Liang|Yu, Hong-Gang|Yu, Jie-Ping|Luo, He-Sheng
PMID: 15112579
Journal: Clin Cancer Res. 2004 May 15;10(10):3333-41.
Title: Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit.
Author: Guo, Jun|Verma, Udit N|Gaynor, Richard B|Frenkel, Eugene P|Becerra, Carlos R
PMID: 15161687
Journal: Am J Physiol Lung Cell Mol Physiol. 2004 Nov;287(5):L981-91.
Title: Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer.
Author: Martey, Christine A|Pollock, Stephen J|Turner, Chantal K|O'Reilly, Katherine M A|Baglole, Carolyn J|Phipps, Richard P|Sime, Patricia J
PMID: 15234907
Journal: Neoplasma. 2004;51(4):319-24.
Title: Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation.
Author: Melen-Mucha, G|Balcerczak, E|Mucha, S|Panczyk, M|Lipa, S|Mirowski, M
PMID: 15254665
Journal: World J Gastroenterol. 2004 Nov 15;10(22):3255-60.
Title: Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue.
Author: Yu, Liang-Liang|Yu, Hong-Gang|Yu, Jie-Ping|Luo, He-Sheng|Xu, Xi-Ming|Li, Jun-Hua
PMID: 15484295
Journal: J Biol Chem. 2005 Mar 4;280(9):7634-44. Epub 2004 Dec 17.
Title: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
Author: Wang, Ling-Chi|Okitsu, Cindy Yen|Zandi, Ebrahim
PMID: 15611081
Journal: Int J Biochem Cell Biol. 2005 Mar;37(3):645-54.
Title: Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation.
Author: Chen, Fei|Harrison, Lawrence E
PMID: 15618021
Journal: Cancer Biol Ther. 2005 Feb;4(2):175-80. Epub 2005 Feb 8.
Title: Selenomethionine regulates cyclooxygenase-2 (COX-2) expression through nuclear factor-kappa B (NF-kappaB) in colon cancer cells.
Author: Cherukuri, Durga P|Goulet, Anne-Christine|Inoue, Hiroyasu|Nelson, Mark A
PMID: 15655349
Journal: DNA Cell Biol. 2005 Apr;24(4):209-17.
Title: Synergy between deacetylase inhibitors and IL-1beta in activation of the serum amyloid A2 gene promoter.
Author: Blais, Mylene|Desilets, Antoine|Asselin, Claude
PMID: 15812237
Journal: FEBS Lett. 2005 Aug 15;579(20):4213-8.
Title: Diclofenac attenuates Wnt/beta-catenin signaling in colon cancer cells by activation of NF-kappaB.
Author: Cho, Munju|Gwak, Jungsug|Park, Seoyoung|Won, Jaejoon|Kim, Dong-Eun|Yea, Sung Su|Cha, In-June|Kim, Tae Kook|Shin, Jae-Gook|Oh, Sangtaek
PMID: 16051228
Journal: Int J Cancer. 2006 Jan 15;118(2):279-83.
Title: Nuclear factor kappaB is downregulated and correlates with p53 in the Min mouse mucosa during an accelerated tumor growth.
Author: Rajakangas, Johanna|Pajari, Anne-Maria|Misikangas, Marjo|Mutanen, Marja
PMID: 16049962
Journal: Int J Cancer. 2006 Feb 1;118(3):532-9.
Title: Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells.
Author: Shah, Syed A|Volkov, Yuri|Arfin, Qamrul|Abdel-Latif, Mohamed M|Kelleher, Dermot
PMID: 16106402
Journal: Biochem Pharmacol. 2006 Feb 28;71(5):634-45. Epub 2005 Dec 19.
Title: Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.
Author: Liang, Mei-Chih|Bardhan, Sujata|Pace, Emily A|Rosman, Diana|Beutler, John A|Porco, John A Jr|Gilmore, Thomas D
PMID: 16360644
Journal: Carcinogenesis. 2006 May;27(5):956-61. Epub 2006 Jan 9.
Title: Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress.
Author: Derdak, Zoltan|Fulop, Peter|Sabo, Edmond|Tavares, Rose|Berthiaume, Eric P|Resnick, Murray B|Paragh, Gyorgy|Wands, Jack R|Baffy, Gyorgy
PMID: 16401637
Journal: J Agric Food Chem. 2006 Feb 8;54(3):980-5.
Title: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
Author: Adams, Lynn S|Seeram, Navindra P|Aggarwal, Bharat B|Takada, Yasunari|Sand, Daniel|Heber, David
PMID: 16448212
Journal: Int J Oncol. 2006 Mar;28(3):695-704.
Title: Inhibition of NF-kappaB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells.
Author: Laos, Sirle|Baeckstrom, Dan|Hansson, Gunnar C
PMID: 16465375
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Anticancer Res. 2006 Mar-Apr;26(2A):1281-8.
Title: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.
Author: Su, Chin-Cheng|Chen, Guang-Wei|Lin, Jaung-Geng|Wu, Lii-Tzu|Chung, Jing-Gung
PMID: 16619535
Journal: Mol Carcinog. 2006 Sep;45(9):685-93.
Title: Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase.
Author: Choi, Woonyoung|Proctor, Lynsey|Xia, Qianghua|Feng, Yumei|Gerner, Eugene W|Chiao, Paul J|Hamilton, Stanley R|Zhang, Wei
PMID: 16637064
Journal: Carcinogenesis. 2007 May;28(5):968-76. Epub 2006 Nov 28.
Title: Aspirin activates the NF-kappaB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer.
Author: Stark, Lesley A|Reid, Kirsten|Sansom, Owen J|Din, Farhat V|Guichard, Sylvie|Mayer, Iain|Jodrell, Duncan I|Clarke, Alan R|Dunlop, Malcolm G
PMID: 17132819
Journal: Mol Carcinog. 2007 May;46(5):402-13.
Title: Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells.
Author: Fukuyama, Ryuichi|Ng, Kwok Peng|Cicek, Muzaffer|Kelleher, Clare|Niculaita, Roxana|Casey, Graham|Sizemore, Nywana
PMID: 17186550
Journal: Cancer Res. 2007 Feb 15;67(4):1660-9.
Title: p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells.
Author: Thoms, Hazel C|Dunlop, Malcolm G|Stark, Lesley A
PMID: 17308107
Journal: Int J Cancer. 2007 Jul 15;121(2):431-41.
Title: TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response.
Author: Nowis, Dominika|McConnell, Elizabeth J|Dierlam, Lindsey|Palamarchuk, Alla|Lass, Agnieszka|Wojcik, Cezary
PMID: 17373661
Journal: Cell Cycle. 2007 Jun 1;6(11):1293-7. Epub 2007 Jun 19.
Title: CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA.
Author: Thoms, Hazel C|Dunlop, Malcolm G|Stark, Lesley A
PMID: 17525529
Journal: Rozhl Chir. 2007 May;86(5):268-72.
Title: [NF-kappaB, colorectal carcinoma and radiotherapy: results of a clinical and experimental study].
Author: Voboril, R|Weberova-Voborilova, J|Rychterova, V|Ambrus, M|Horak, L|Fanta, J
PMID: 17634017
Journal: Cancer Res. 2007 Aug 1;67(15):7368-77.
Title: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.
Author: Lluis, Josep M|Buricchi, Francesca|Chiarugi, Paola|Morales, Albert|Fernandez-Checa, Jose C
PMID: 17671207
Journal: Cancer Res. 2007 Aug 15;67(16):7773-81.
Title: Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition.
Author: Wang, Qingding|Zhou, Yuning|Wang, Xiaofu|Chung, Dai H|Evers, B Mark
PMID: 17699782
Journal: Toxicol Appl Pharmacol. 2007 Dec 1;225(2):198-205. Epub 2007 Aug 2.
Title: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice.
Author: Lee, Sei-Jung|Lim, Kye-Taek
PMID: 17868752
Journal: Mol Cancer Ther. 2007 Oct;6(10):2786-97.
Title: Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway.
Author: Lee, Seung Ho|Son, Seung Mo|Son, Dong Ju|Kim, Sun Mi|Kim, Tack Joong|Song, Sukgil|Moon, Dong Cheul|Lee, Hyo Won|Ryu, Jae Chun|Yoon, Do-Young|Hong, Jin Tae
PMID: 17938270
Journal: Neoplasma. 2007;54(6):495-502.
Title: Sensitization of colorectal cancer cells to irradiation by IL-4 and IL-10 is associated with inhibition of NF-kappaB.
Author: Voboril, R|Weberova-Voborilova, J
PMID: 17949233
Journal: Int J Biomed Sci. 2007 Dec;3(4):287-91.
Title: Quantitative analysis of the p65 gene expression in patients with coloroctal cancer.
Author: Balcerczak, E|Balcerczak, M|Mirowski, M
PMID: 23675055
Journal: Oncogene. 2008 Apr 17;27(18):2648-55. Epub 2007 Dec 3.
Title: The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.
Author: Loveridge, C J|MacDonald, A D H|Thoms, H C|Dunlop, M G|Stark, L A
PMID: 18059344
Journal: Eur J Pharmacol. 2008 Mar 17;582(1-3):17-25.
Title: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.
Author: Lee, So Yong|Yuk, Dong Yeon|Song, Ho Seub|Yoon, Do Young|Jung, Jae Kyung|Moon, Dong Cheul|Lee, Byung Seok|Hong, Jin Tae
PMID: 18241858
Journal: Clin Exp Metastasis. 2008;25(4):491-6.
Title: Dissociated invasively growing cancer cells with NF-kappaB/p65 positivity after radiotherapy: a new marker for worse clinical outcome in rectal cancer? Preliminary data.
Author: Voboril, Rene|Voborilova, Jana|Rychterova, Vlasta|Jirasek, Tomas|Dvorak, Josef
PMID: 18324356
Journal: Oncol Rep. 2008 Jul;20(1):41-7.
Title: Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kappaB in HCT116 colon cancer cells.
Author: Lee, Hye Ran|Cheong, Hee-Jeong|Kim, Sook-Ja|Lee, Nam-Su|Park, Hee-Sook|Won, Jong-Ho
PMID: 18575716
Journal: Zhonghua Yi Xue Za Zhi. 2008 Mar 4;88(9):610-4.
Title: [Expression of nuclear factor-kappa-B/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof].
Author: Lu, Yang|Liu, Lin|Zhao, Po
PMID: 18646716
Journal: Cell Biol Int. 2008 Oct;32(10):1207-14.
Title: NF-kappaB-dependency and consequent regulation of IL-8 in echinomycin-induced apoptosis of HT-29 colon cancer cells.
Author: Park, Ju Youn|Chang, Jae-Ho|Bae, Keum Seok|Lee, Kyoung Ho|Choi, Sun Ju|Park, Joo Young|Ryang, Yong Suk|Kim, Soo-Ki
PMID: 18675368
Journal: Korean J Gastroenterol. 2008 Dec;52(6):359-67.
Title: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa].
Author: Lee, Sang Dae
PMID: 19096253
Journal: Acta Pol Pharm. 2008 Nov-Dec;65(6):697-702.
Title: Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells.
Author: Kapral, Malgorzata|Parfiniewicz, Beata|Strzalka-Mrozik, Barbara|Zachacz, Agnieszka|Weglarz, Ludmila
PMID: 19172851
Journal: Pathol Oncol Res. 2009 Mar;15(1):31-6.
Title: Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer.
Author: Qiao, Liang|Wang, Yan|Pang, Roberta|Wang, Jide|Dai, Yun|Ma, Juan|Gu, Qing|Li, Zesong|Zhang, Yusheng|Zou, Bing|Lan, H Y|Wong, Benjamin C Y
PMID: 18752053
Journal: Int J Colorectal Dis. 2009 Feb;24(2):151-7.
Title: High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma.
Author: Stanilov, Noyko|Miteva, Lyuba|Mintchev, Nikolay|Stanilova, Spaska
PMID: 18825388
Journal: Nutrition. 2009 May;25(5):555-66.
Title: Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells.
Author: Xu, Wei-Li|Liu, Jia-Ren|Liu, Hui-Kun|Qi, Gui-Yun|Sun, Xiang-Rong|Sun, Wen-Guang|Chen, Bing-Qing
PMID: 19121919
Journal: Chem Biol Interact. 2009 May 15;179(2-3):202-11.
Title: Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling.
Author: Prawan, Auemduan|Saw, Constance Lay Lay|Khor, Tin Oo|Keum, Young-Sam|Yu, Siwang|Hu, Longqin|Kong, Ah-Ng
PMID: 19159619
Journal: Cancer Res. 2009 May 1;69(9):3764-71.
Title: Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells.
Author: Du, Qiang|Zhang, Xinglu|Cardinal, Jon|Cao, Zongxian|Guo, Zhong|Shao, Lifang|Geller, David A
PMID: 19383900
Journal: Br J Cancer. 2009 Jul 7;101(1):106-15.
Title: Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue.
Author: Charalambous, M P|Lightfoot, T|Speirs, V|Horgan, K|Gooderham, N J
PMID: 19513071
Journal: Eur J Pharmacol. 2009 Sep 15;618(1-3):91-7.
Title: An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation.
Author: Joo, Kanghyun|Lee, Youna|Choi, Deakyu|Han, Jeongoh|Hong, Sungchae|Kim, Young Mi|Jung, Yunjin
PMID: 19616541
Journal: Br J Cancer. 2009 Nov 3;101(9):1596-605.
Title: Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells.
Author: Mezhybovska, M|Yudina, Y|Abhyankar, A|Sjolander, A
PMID: 19826421
Journal: J Nat Prod. 2009 Nov;72(11):2028-31.
Title: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
Author: Han, Ah-Reum|Kim, Jeong-Ah|Lantvit, Daniel D|Kardono, Leonardus B S|Riswan, Soedarsono|Chai, Heebyung|Carcache de Blanco, Esperanza J|Farnsworth, Norman R|Swanson, Steven M|Kinghorn, A Douglas
PMID: 19839614
Journal: Carcinogenesis. 2010 Jul;31(7):1272-8.
Title: Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats.
Author: Paul, Shiby|DeCastro, Andrew J|Lee, Hong Jin|Smolarek, Amanda K|So, Jae Young|Simi, Barbara|Wang, Chung Xiou|Zhou, Renping|Rimando, Agnes M|Suh, Nanjoo
PMID: 20061362
Journal: Phytochemistry. 2010 Apr;71(5-6):635-40.
Title: Bioactivity-guided isolation of cytotoxic sesquiterpenes of Rolandra fruticosa.
Author: Pan, Li|Lantvit, Daniel D|Riswan, Soedarsono|Kardono, Leonardus B S|Chai, Hee-Byung|de Blanco, Esperanza J Carcache|Farnsworth, Norman R|Soejarto, Djaja Doel|Swanson, Steven M|Kinghorn, A Douglas
PMID: 20189206
Journal: J Nat Prod. 2010 May 28;73(5):949-55.
Title: Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.
Author: Ren, Yulin|Kardono, Leonardus B S|Riswan, Soedarsono|Chai, Heebyung|Farnsworth, Norman R|Soejarto, Djaja D|Carcache de Blanco, Esperanza J|Kinghorn, A Douglas
PMID: 20384315
Journal: Oncology. 2010;78(3-4):181-8.
Title: NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer.
Author: Puvvada, Soham D|Funkhouser, William K|Greene, Kevin|Deal, Allison|Chu, Haitao|Baldwin, Albert S|Tepper, Joel E|O'Neil, Bert H
PMID: 20414006
Journal: J Cell Sci. 2010 Jun 15;123(Pt 12):2135-43.
Title: Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells.
Author: Gavert, Nancy|Ben-Shmuel, Amir|Lemmon, Vance|Brabletz, Thomas|Ben-Ze'ev, Avri
PMID: 20501702
Journal: J Cell Physiol. 2010 Oct;225(1):266-75.
Title: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.
Author: Yang, Zhengfeng|Li, Chenghai|Wang, Xiu|Zhai, Chunyan|Yi, Zhengfang|Wang, Lei|Liu, Bisheng|Du, Bing|Wu, Huihui|Guo, Xizhi|Liu, Mingyao|Li, Dali|Luo, Jian
PMID: 20509140
Journal: J Biol Chem. 2010 Aug 13;285(33):25458-66.
Title: Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Author: Chen, Jinn-Shiun|Hsu, Yuan-Ming|Chen, Chia-Chi|Chen, Li-Li|Lee, Chun-Chung|Huang, Tze-Sing
PMID: 20558745
Journal: Cancer Lett. 2010 Dec 8;298(2):204-11.
Title: NO-releasing NSAIDs suppress NF-kappaB signaling in vitro and in vivo through S-nitrosylation.
Author: Chattopadhyay, Mitali|Goswami, Satindra|Rodes, Deborah B|Kodela, Ravinder|Velazquez, Carlos A|Boring, Daniel|Crowell, James A|Kashfi, Khosrow
PMID: 20674154
Journal: Folia Microbiol (Praha). 2010 Nov;55(6):657-61.
Title: Quantitative evaluation of transcriptional activation of NF-kappaB p65 and p50 subunits and IkappaBalpha encoding genes in colon cancer cells by Desulfovibrio desulfuricans endotoxin.
Author: Kapral, M|Weglarz, L|Parfiniewicz, B|Lodowska, J|Jaworska-Kik, M
PMID: 21253915
Journal: Biomedica. 2010 Oct-Dec;30(4):577-86.
Title: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells.
Author: Maldonado, Maria Elena|Bousserouel, Souad|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 21713362
Journal: Invest New Drugs. 2011 Apr;29(2):207-24.
Title: Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2.
Author: Nagendraprabhu, Ponnuraj|Sudhandiran, Ganapasam
PMID: 19876598
Journal: Int J Cancer. 2011 Jun 1;128(11):2581-90.
Title: NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Author: Wang, Rong|Dashwood, Wan-Mohaiza|Nian, Hui|Lohr, Christiane V|Fischer, Kay A|Tsuchiya, Naoto|Nakagama, Hitoshi|Ashktorab, Hassan|Dashwood, Roderick H
PMID: 20715105
Journal: Front Biosci (Elite Ed). 2011 Jan 1;3:410-20.
Title: Sage components enhance cell death through nuclear factor kappa-B signaling.
Author: Deeb, Sally Joseph|El-Baba, Chirine Omar|Hassan, Saadia Bashir|Larsson, Rolf Lennart|Gali-Muhtasib, Hala Uthman
PMID: 21196321
Journal: Bioorg Med Chem. 2011 Mar 15;19(6):1895-906.
Title: New bichalcone analogs as NF-kappaB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis.
Author: Reddy, M Vijaya Bhaskar|Shen, Yuh-Chiang|Yang, Jai-Sing|Hwang, Tsong-Long|Bastow, Kenneth F|Qian, Keduo|Lee, Kuo-Hsiung|Wu, Tian-Shung
PMID: 21377368
Journal: Biochem J. 2011 Jun 1;436(2):507-16.
Title: Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells.
Author: Yang, Heping|Li, Tony W H|Peng, Jian|Mato, Jose M|Lu, Shelly C
PMID: 21406062
Journal: Exp Cell Res. 2011 Jun 10;317(10):1359-67.
Title: Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action.
Author: Williams, Jennie L|Ji, Ping|Ouyang, Nengtai|Kopelovich, Levy|Rigas, Basil
PMID: 21406194
Journal: Angiogenesis. 2011 May;14(2):209-21.
Title: Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo.
Author: Tammali, Ravinder|Reddy, Aramati B M|Srivastava, Satish K|Ramana, Kota V
PMID: 21409599
Journal: J Nat Prod. 2011 May 27;74(5):1117-25.
Title: Cytotoxic and NF-kappaB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues.
Author: Ren, Yulin|Matthew, Susan|Lantvit, Daniel D|Ninh, Tran Ngoc|Chai, Heebyung|Fuchs, James R|Soejarto, Djaja D|de Blanco, Esperanza J Carcache|Swanson, Steven M|Kinghorn, A Douglas
PMID: 21428375
Journal: Cancer Biol Ther. 2011 Jul 1;12(1):59-68.
Title: Gallotannin inhibits NFkB signaling and growth of human colon cancer xenografts.
Author: Al-Halabi, Racha|Bou Chedid, Mirella|Abou Merhi, Raghida|El-Hajj, Hiba|Zahr, Hind|Schneider-Stock, Regine|Bazarbachi, Ali|Gali-Muhtasib, Hala
PMID: 21532339
Journal: Biochim Biophys Acta. 2011 Aug;1812(8):851-8.
Title: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-kappaB signaling in the intestine.
Author: Gadaleta, Raffaella M|Oldenburg, Bas|Willemsen, Ellen C L|Spit, Maureen|Murzilli, Stefania|Salvatore, Lorena|Klomp, Leo W J|Siersema, Peter D|van Erpecum, Karel J|van Mil, Saskia W C
PMID: 21540105
Journal: J Cell Biochem. 2011 Sep;112(9):2490-501.
Title: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma.
Author: Cimen, I|Astarci, E|Banerjee, S
PMID: 21544861
Journal: Carcinogenesis. 2011 Jul;32(7):1069-77.
Title: c-Src dependency of NSAID-induced effects on NF-kappaB-mediated apoptosis in colorectal cancer cells.
Author: Brady, Richard R W|Loveridge, Carolyn J|Dunlop, Malcolm G|Stark, Lesley A
PMID: 21551129
Journal: PLoS One. 2011;6(5):e19628.
Title: Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa.
Author: Aviello, Gabriella|Canadanovic-Brunet, Jasna M|Milic, Natasa|Capasso, Raffaele|Fattorusso, Ernesto|Taglialatela-Scafati, Orazio|Fasolino, Ines|Izzo, Angelo A|Borrelli, Francesca
PMID: 21625488
Journal: Tumour Biol. 2011 Oct;32(5):921-30.
Title: Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620.
Author: Guo, Donglin|Zhou, Hong|Wu, Ying|Zhou, Fang|Xu, Guoying|Wen, Haiping|Zhang, Xianmei
PMID: 21625939
Journal: BMC Cancer. 2011 Jul 1;11:285.
Title: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3.
Author: Porquet, Nicolas|Poirier, Andree|Houle, Francois|Pin, Anne-Laure|Gout, Stephanie|Tremblay, Pierre-Luc|Paquet, Eric R|Klinck, Roscoe|Auger, Francois A|Huot, Jacques
PMID: 21722370
Journal: Clin Cancer Res. 2011 Sep 1;17(17):5686-94.
Title: Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer.
Author: Chu, Dake|Zhou, Yi|Zhang, Zixi|Li, Yuming|Li, Jipeng|Zheng, Jianyong|Zhang, Hongwei|Zhao, Qingchuan|Wang, Weizhong|Wang, Rui'an|Ji, Gang
PMID: 21771876
Journal: BMC Cancer. 2011 Aug 24;11:371.
Title: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Lei, Ping|Pathi, Satya|Safe, Stephen
PMID: 21864401
Journal: Cancer Biol Ther. 2011 Nov 1;12(9):797-807.
Title: C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFkappaB in colon cancer cells and xenograft tumors.
Author: Chen, Chun|Liu, Yang|Chen, Yuanzhong|Xu, Jianhua
PMID: 21900746
Journal: Int Immunopharmacol. 2011 Dec;11(12):2104-11.
Title: 3'-Chloro-5,7-dimethoxyisoflavone inhibits TNFalpha-induced CXCL10 gene transcription by suppressing the NF-kappaB pathway in HCT116 human colon cancer cells.
Author: Shin, Soon Young|Hyun, Jiye|Lim, Yoongho|Lee, Young Han
PMID: 21945666
Journal: Clin Cancer Res. 2011 Dec 15;17(24):7551-62.
Title: Epigenetic alteration of PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFalpha-induced apoptosis.
Author: Lee, Jin-Hee|Kang, Min-Ju|Han, Hye-Yeon|Lee, Min-Goo|Jeong, Seong-In|Ryu, Byung-Kyu|Ha, Tae-Kyu|Her, Nam-Goo|Han, Jikhyon|Park, Sun Jin|Lee, Kil Yeon|Kim, Hyo-Jong|Chi, Sung-Gil
PMID: 21980136
Journal: Pharmacol Rep. 2011;63(5):1210-21.
Title: Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer.
Author: Vaish, Vivek|Sanyal, Sankar N
PMID: 22180364
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Sep;33(9):649-53.
Title: [Role of NF-kappaB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells].
Author: Guo, Dong-lin|Zhou, Hong|Wu, Ying|Zhou, Fang|Zhang, Xian-mei|Xu, Guo-ying|Wen, Hai-ping
PMID: 22340043
Journal: Radiol Oncol. 2011 Dec;45(4):279-84.
Title: Expression of NF-kappaB p65 phosphorylated at serine-536 in rectal cancer with or without preoperative radiotherapy.
Author: Lewander, Andreas|Gao, Jinfang|Adell, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 22933966
Journal: Mol Carcinog. 2012 Jun;51(6):475-90.
Title: Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells.
Author: Babykutty, Suboj|S, Priya P|J, Nandini R|Kumar, M A Suresh|Nair, Mangalam S|Srinivas, Priya|Gopala, Srinivas
PMID: 21678498
Journal: Mol Carcinog. 2012 Nov;51(11):869-80.
Title: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice.
Author: Park, Heesook|Kim, Minhee|Kwon, Gyoo Taik|Lim, Do Young|Yu, Rina|Sung, Mi-Kyung|Lee, Ki Won|Daily, James W 3rd|Park, Jung Han Yoon
PMID: 21919080
Journal: Acta Pharmacol Sin. 2012 Jan;33(1):120-6.
Title: Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro.
Author: Zhou, Fang|Zhou, Hong|Wang, Ting|Mu, Yuan|Wu, Biao|Guo, Dong-lin|Zhang, Xian-mei|Wu, Ying
PMID: 22101170
Journal: Int J Colorectal Dis. 2012 Apr;27(4):447-52.
Title: NF-kappaB p65 phosphorylated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients.
Author: Lewander, Andreas|Gao, Jinfang|Carstensen, John|Arbman, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 22102084
Journal: J Nutr Biochem. 2012 Oct;23(10):1302-13.
Title: Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model.
Author: Tang, Feng-Yao|Pai, Man-Hui|Chiang, En-Pei Isabel
PMID: 22221675
Journal: Oncol Rep. 2012 May;27(5):1527-34.
Title: NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBalpha pathway.
Author: Lin, Gen|Tang, Zhiwei|Ye, Yun-Bin|Chen, Qiang
PMID: 22327383
Journal: Mol Cancer Ther. 2012 Apr;11(4):984-93.
Title: Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer.
Author: Seavey, Matthew M|Lu, Lily D|Stump, Kristine L|Wallace, Nate H|Hockeimer, William|O'Kane, Teresa M|Ruggeri, Bruce A|Dobrzanski, Pawel
PMID: 22334590
Journal: Carcinogenesis. 2012 Jun;33(6):1158-68.
Title: Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
Author: Wang, Tz-Ping|Hsu, Shu-Han|Feng, Hsin-Chun|Huang, Rwei-Fen S
PMID: 22461522
Journal: Carcinogenesis. 2012 Jun;33(6):1193-202.
Title: N-alpha-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression.
Author: Xu, Huiyu|Jiang, Beihai|Meng, Lin|Ren, Tingting|Zeng, Yan|Wu, Jian|Qu, Like|Shou, Chengchao
PMID: 22496479
Journal: PLoS One. 2012;7(4):e33031.
Title: Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines.
Author: De Stefano, Daniela|Tommonaro, Giuseppina|Malik, Shoaib Ahmad|Iodice, Carmine|De Rosa, Salvatore|Maiuri, Maria Chiara|Carnuccio, Rosa
PMID: 22509253
Journal: Oncol Rep. 2012 Jul;28(1):358-64.
Title: HIV-1 viral protein R (Vpr) induction of apoptosis and cell cycle arrest in multidrug-resistant colorectal cancer cells.
Author: Ma, Bo|Zhang, Hanchao|Wang, Jinhuan|Zhang, Biao|Xu, Xinnv|Cheng, Binglu
PMID: 22552851
Journal: Tetrahedron. 2012 Mar 25;68(12):2671-2678.
Title: Cytotoxic and NF-kappaB inhibitory sesquiterpene lactones from Piptocoma rufescens.
Author: Ren, Yulin|Acuna, Ulyana Munoz|Jimenez, Francisco|Garcia, Ricardo|Mejia, Melciades|Chai, Heebyung|Gallucci, Judith C|Farnsworth, Norman R|Soejarto, Djaja D|Carcache de Blanco, Esperanza J|Kinghorn, A Douglas
PMID: 22685350
Journal: Zhonghua Nei Ke Za Zhi. 2012 Mar;51(3):220-4.
Title: [The expression and clinical significance of SphK1 and nuclear factor-kappaB p65 in human colon carcinoma].
Author: Su, Ying-jie|Huang, Jie-an|Liu, Shi-quan|Huang, Juan-xiu|Zhong, Yue-yuan|Tang, Guo-du|Jiang, Hai-xing
PMID: 22781898
Journal: J Biol Chem. 2012 Nov 30;287(49):41364-73.
Title: beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells.
Author: Hwang, Injoo|Kim, Jeeho|Jeong, Sunjoo
PMID: 23086933
Journal: PLoS One. 2012;7(10):e48208.
Title: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Jutooru, Indira|Chadalapaka, Gayathri|Nair, Vijayalekshmi|Lee, Syng-Ook|Safe, Stephen
PMID: 23110215
Journal: Exp Ther Med. 2012 Oct;4(4):716-722.
Title: Effect of NF-kappaB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29.
Author: Liu, Ting|Liu, Dan|Liu, Jing|Song, Ji-Tao|Gao, Shan-Ling|Li, Hui|Hu, Li-Hong|Liu, Bing-Rong
PMID: 23170132
Journal: BMC Cancer. 2012 Nov 30;12:564.
Title: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
Author: Gandhy, Shruti U|Kim, Kyounghyun|Larsen, Lesley|Rosengren, Rhonda J|Safe, Stephen
PMID: 23194063
Journal: Oncoimmunology. 2012 Dec 1;1(9):1495-1506.
Title: A TLR4-interacting peptide inhibits lipopolysaccharide-stimulated inflammatory responses, migration and invasion of colon cancer SW480 cells.
Author: Rakhesh, Madhusoodhanan|Cate, Moriasi|Vijay, Ramani|Shrikant, Anant|Shanjana, Awasthi
PMID: 23264896
Journal: Mol Carcinog. 2013 Mar;52(3):195-206.
Title: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling.
Author: Raina, Komal|Agarwal, Chapla|Agarwal, Rajesh
PMID: 22086675
Journal: Mol Carcinog. 2013 Dec;52(12):997-1006.
Title: Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression.
Author: Harvey, Alison E|Lashinger, Laura M|Otto, Glen|Nunez, Nomeli P|Hursting, Stephen D
PMID: 22778026
Journal: J Mol Med (Berl). 2013 Apr;91(4):449-58.
Title: O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms.
Author: Kargl, Julia|Haybaeck, Johannes|Stancic, Angela|Andersen, Liisa|Marsche, Gunther|Heinemann, Akos|Schicho, Rudolf
PMID: 22965195
Journal: Biochem Biophys Res Commun. 2013 Jan 4;430(1):196-201.
Title: PRL-3 activates NF-kappaB signaling pathway by interacting with RAP1.
Author: Lian, Shenyi|Meng, Lin|Liu, Caiyun|Xing, Xiaofang|Song, Qian|Dong, Bin|Han, Yong|Yang, Yongyong|Peng, Lirong|Qu, Like|Shou, Chengchao
PMID: 23178297
Journal: Food Funct. 2013 Feb 26;4(3):366-72.
Title: Chemopreventive properties of raisins originating from Greece in colon cancer cells.
Author: Kountouri, Aggeliki M|Gioxari, Aristea|Karvela, Evangelia|Kaliora, Andriana C|Karvelas, Michalis|Karathanos, Vaios T
PMID: 23211994
Journal: Cell. 2013 Jan 17;152(1-2):25-38.
Title: Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.
Author: Schwitalla, Sarah|Fingerle, Alexander A|Cammareri, Patrizia|Nebelsiek, Tim|Goktuna, Serkan I|Ziegler, Paul K|Canli, Ozge|Heijmans, Jarom|Huels, David J|Moreaux, Guenievre|Rupec, Rudolf A|Gerhard, Markus|Schmid, Roland|Barker, Nick|Clevers, Hans|Lang, Rola
PMID: 23273993
Journal: Int J Oncol. 2013 Feb;42(2):643-50.
Title: A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats.
Author: Ouyang, Nengtai|Ji, Ping|Williams, Jennie L
PMID: 23291777
Journal: J Nat Prod. 2013 Mar 22;76(3):394-404.
Title: Bioactive flavaglines and other constituents isolated from Aglaia perviridis.
Author: Pan, Li|Acuna, Ulyana Munoz|Li, Jie|Jena, Nivedita|Ninh, Tran Ngoc|Pannell, Caroline M|Chai, Heebyung|Fuchs, James R|Carcache de Blanco, Esperanza J|Soejarto, Djaja D|Kinghorn, A Douglas
PMID: 23301897
Journal: Food Chem Toxicol. 2013 May;55:229-33.
Title: Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells.
Author: Jeong, Jin Boo|Shin, Yong Kyu|Lee, Seong-Ho
PMID: 23348408
Journal: PLoS One. 2013;8(3):e58055.
Title: Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole andrographolide derivatives.
Author: Dey, Sumit Kumar|Bose, Dipayan|Hazra, Abhijit|Naskar, Subhendu|Nandy, Abhishek|Munda, Rudra Narayan|Das, Subhadip|Chatterjee, Nabanita|Mondal, Nirup Bikash|Banerjee, Sukdeb|Saha, Krishna Das
PMID: 23472133
Journal: Biochem Biophys Res Commun. 2013 May 17;434(4):760-6.
Title: PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells.
Author: Liu, Jingyi|Liao, Yueling|Ma, Kewei|Wang, Yonglu|Zhang, Guoxiang|Yang, Rongcun|Deng, Jiong
PMID: 23583404
Journal: Int Immunopharmacol. 2013 Jun;16(2):184-90.
Title: Patchouli alcohol, an essential oil of Pogostemon cablin, exhibits anti-tumorigenic activity in human colorectal cancer cells.
Author: Jeong, Jin Boo|Choi, Jieun|Lou, Zhiyuan|Jiang, Xiaojing|Lee, Seong-Ho
PMID: 23602914
Journal: Mol Cancer Res. 2013 Jul;11(7):724-35.
Title: Epigenetic control of NF-kappaB-dependent FAS gene transcription during progression of myelodysplastic syndromes.
Author: Ettou, Sandrine|Humbrecht, Catherine|Benet, Blandine|Billot, Katy|d'Allard, Diane|Mariot, Virginie|Goodhardt, Michele|Kosmider, Olivier|Mayeux, Patrick|Solary, Eric|Fontenay, Michaela
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Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 May;33(5):649-53.
Title: [CaMKIIgamma promotes in vitro and in vivo growth of colorectal cancer cells by upregulating nuclear factor-kappaB signaling pathway].
Author: Xu, Fei|Qi, Haiyan|Yu, Xiaofang|Xu, Rongzhen
PMID: 23688981
Journal: Carcinogenesis. 2013 Oct;34(10):2350-60.
Title: A mechanistic study of the proapoptotic effect of tolfenamic acid: involvement of NF-kappaB activation.
Author: Jeong, Jin Boo|Yang, Xuyu|Clark, Ruth|Choi, Jieun|Baek, Seung Joon|Lee, Seong-Ho
PMID: 23784084
Journal: Arch Biochem Biophys. 2013 Sep 15;537(2):168-75.
Title: Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells.
Author: Jeong, Jin Boo|Choi, Jieun|Baek, Seung Joon|Lee, Seong-Ho
PMID: 23896517
Journal: Acta Med Indones. 2013 Jul;45(3):187-92.
Title: Expression of NF-kB and COX2 in colorectal cancer among native Indonesians: the role of inflammation in colorectal carcinogenesis.
Author: Abdullah, Murdani|Rani, A Aziz|Sudoyo, Aru W|Makmun, Dadang|Handjari, Diah R|Hernowo, Bethy S
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Journal: Carcinogenesis. 2013 Dec;34(12):2842-50.
Title: Dietary black raspberries modulate DNA methylation in dextran sodium sulfate (DSS)-induced ulcerative colitis.
Author: Wang, Li-Shu|Kuo, Chieh-Ti|Stoner, Kristen|Yearsley, Martha|Oshima, Kiyoko|Yu, Jianhua|Huang, Tim H-M|Rosenberg, Daniel|Peiffer, Dan|Stoner, Gary|Huang, Yi-Wen
PMID: 24067901
Journal: Cell Commun Signal. 2013 Oct 1;11:73.
Title: Sulindac activates NF-kappaB signaling in colon cancer cells.
Author: Mladenova, Dessislava|Pangon, Laurent|Currey, Nicola|Ng, Irvin|Musgrove, Elizabeth A|Grey, Shane T|Kohonen-Corish, Maija R J
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Journal: Cell Physiol Biochem. 2013;32(6):1587-99.
Title: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-kappaB pathway.
Author: Xiao, Ming|Tang, Yi|Wang, Ya-Lan|Yang, Lian|Li, Xian|Kuang, Jing|Song, Guang-Lin
PMID: 24335275
Journal: J Environ Pathol Toxicol Oncol. 2013;32(4):275-88.
Title: Fermented Pu-erh tea increases in vitro anticancer activities in HT-29 cells and has antiangiogenetic effects on HUVECs.
Author: Zhao, Xin|Song, Jia-Le|Kim, Jong-Deog|Lee, Jong-Suk|Park, Kun-Young
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Journal: Int J Cancer Res. 2013;9(2):36-53.
Title: Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo.
Author: Acuna, Ulyana Munoz|Shen, Qi|Ren, Yulin|Lantvit, Daniel D|Wittwer, Jennifer A|Kinghorn, A Douglas|Swanson, Steven M|de Blanco, Esperanza J Carcache
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Journal: Clin Nutr. 2014 Feb;33(1):164-70.
Title: Interaction of omega-3 polyunsaturated fatty acids with radiation therapy in two different colorectal cancer cell lines.
Author: Cai, Fang|Sorg, Olivier|Granci, Virginie|Lecumberri, Elena|Miralbell, Raymond|Dupertuis, Yves M|Pichard, Claude
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Journal: Food Chem. 2014 Jan 1;142:233-41.
Title: Phenolic profiles and antioxidant and anticarcinogenic activities of Greek herbal infusions; balancing delight and chemoprevention?
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Journal: Mol Med Rep. 2014 Jan;9(1):249-54.
Title: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB.
Author: Yu, Meiling|Tong, Xuhui|Qi, Benquan|Qu, Hongdang|Dong, Shuying|Yu, Binbin|Zhang, Naiju|Tang, Nan|Wang, Lingzhi|Zhang, Cuiling
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Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36.
Title: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.
Author: Zhang, Jingjing|Dou, Wei|Zhang, Eryun|Sun, Aning|Ding, Lili|Wei, Xiaohui|Chou, Guixin|Mani, Sridhar|Wang, Zhengtao
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Journal: Carcinogenesis. 2014 May;35(5):983-91.
Title: CHIP/Stub1 functions as a tumor suppressor and represses NF-kappaB-mediated signaling in colorectal cancer.
Author: Wang, Yangmeng|Ren, Fangli|Wang, Yinyin|Feng, Yarui|Wang, Dianjun|Jia, Baoqing|Qiu, Ying|Wang, Shiyan|Yu, Jun|Sung, Joseph Jy|Xu, Jiake|Zeps, Nikolajs|Chang, Zhijie
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Journal: Phytother Res. 2014 Jul;28(7):1045-53.
Title: Apoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway.
Author: Acuna, Ulyana Munoz|Matthew, Susan|Pan, Li|Kinghorn, A Douglas|Swanson, Steven M|de Blanco, Esperanza J Carcache
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Journal: Acta Histochem. 2014 Apr;116(3):527-33.
Title: Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling.
Author: Yan, Zhaopeng|Yin, Hongzhuan|Wang, Rui|Wu, Di|Sun, Wei|Liu, Baolin|Su, Qi
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Journal: Exp Cell Res. 2014 May 15;324(1):40-53.
Title: Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Author: Saldanha, Sabita N|Kala, Rishabh|Tollefsbol, Trygve O
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Journal: Virchows Arch. 2014 Jun;464(6):645-54.
Title: Prognostic value of c-FLIPL/s, HIF-1alpha, and NF-kappabeta in stage II and III rectal cancer.
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Journal: J Transl Med. 2014 Apr 26;12:105.
Title: ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition.
Author: Lin, Xiaochang|Yi, Zhiyong|Diao, Jianxin|Shao, Meng|Zhao, Liang|Cai, Hongbing|Fan, Qin|Yao, Xueqing|Sun, Xuegang
PMID: 24766737
Journal: Sci Rep. 2014 May 15;4:4985.
Title: Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer.
Author: Liang, Xujun|Li, Huiying|Tian, Geng|Li, Shao
PMID: 24828543
Journal: Gastroenterology. 2014 Oct;147(4):847-859.e11.
Title: A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFkappaB and STAT3 in colorectal cancer cells.
Author: Liu, Sanhong|Sun, Xiaohua|Wang, Mingliang|Hou, Yingyong|Zhan, Yu|Jiang, Yuhang|Liu, Zhanjie|Cao, Xinwei|Chen, Pengfei|Liu, Zhi|Chen, Xi|Tao, Yu|Xu, Chen|Mao, Jie|Cheng, Chunyan|Li, Cuifeng|Hu, Yiming|Wang, Lunshan|Chin, Y Eugene|Shi, Yufang|Siebenlist, Ul
PMID: 24931456
Journal: BMC Complement Altern Med. 2014 Jun 25;14:200.
Title: Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark.
Author: Eo, Hyun Ji|Park, Jae Ho|Park, Gwang Hun|Lee, Man Hyo|Lee, Jeong Rak|Koo, Jin Suk|Jeong, Jin Boo
PMID: 24962785
Journal: Oncol Rep. 2014 Oct;32(4):1670-80.
Title: Identification of aspirin analogues that repress NF-kappaB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo.
Author: Claudius, Ann-Katrin|Kankipati, Chandra S|Kilari, Rajagopal S|Hassan, Sadiya|Guest, Kerry|Russell, Steven T|Perry, Chris J|Stark, Lesley A|Nicholl, Iain D
PMID: 25109257
Journal: PLoS One. 2014 Aug 14;9(8):e104891.
Title: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Author: Lien, Gi-Shih|Wu, Ming-Shun|Bien, Mauo-Ying|Chen, Chien-Hsin|Lin, Chien-Huang|Chen, Bing-Chang
PMID: 25122478
Journal: BMC Cancer. 2014 Aug 18;14:599.
Title: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs.
Author: Samuel, Temesgen|Fadlalla, Khalda|Gales, Dominique N|Putcha, Balananda D K|Manne, Upender
PMID: 25134433
Journal: Cell Death Dis. 2014 Nov 20;5:e1534.
Title: Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells.
Author: Abe, N|Hou, D-X|Munemasa, S|Murata, Y|Nakamura, Y
PMID: 25412312
Journal: Mol Cells. 2014 Dec 31;37(12):899-906.
Title: Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines.
Author: Shehzad, Adeeb|Ul Islam, Salman|Lee, Jaetae|Lee, Young Sup
PMID: 25431425
Journal: Eur Rev Med Pharmacol Sci. 2014;18(24):3834-43.
Title: The TLR4/NF-kappaB signaling pathway mediates the growth of colon cancer.
Author: Huang, H-Y|Zhang, Z-J|Cao, C-B|Wang, N|Liu, F-F|Peng, J-Q|Ren, X-J|Qian, J
PMID: 25555874
Journal: Phytochem Lett. 2014 Dec;10:54-59.
Title: Bioactive indole alkaloids isolated from Alstonia angustifolia.
Author: Pan, Li|Terrazas, Cesar|Munoz Acuna, Ulyana|Ninh, Tran Ngoc|Chai, Heebyung|Carcache de Blanco, Esperanza J|Soejarto, Djaja D|Satoskar, Abhay R|Kinghorn, A Douglas
PMID: 25584095
Journal: Environ Toxicol. 2015 Jul;30(7):852-63.
Title: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling.
Author: Ma, Yi-Shih|Hsiao, Yu-Ping|Lin, Ju-Hwa|Hsu, Shu-Chun|Chueh, Fu-Shin|Weng, Shu-Wen|Lai, Kuang-Chi|Lin, Jaung-Geng|Chung, Jing-Gung
PMID: 24497447
Journal: Mol Carcinog. 2015 Oct;54(10):1096-109.
Title: Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Author: Li, Weidong|Hua, Baojin|Saud, Shakir M|Lin, Hongsheng|Hou, Wei|Matter, Matthias S|Jia, Libin|Colburn, Nancy H|Young, Matthew R
PMID: 24838344
Journal: J Gastroenterol Hepatol. 2015 Apr;30(4):680-8.
Title: Ubiquitin D is an independent prognostic marker for survival in stage IIB-IIC colon cancer patients treated with 5-fluoruracil-based adjuvant chemotherapy.
Author: Zhao, Senlin|Jiang, Tao|Tang, Huamei|Cui, Feifei|Liu, Chenchen|Guo, Feng|Lu, Huijun|Xue, Yingming|Jiang, Weiliang|Peng, Zhihai|Yan, Dongwang
PMID: 25238407
Journal: Tumour Biol. 2015 May;36(5):3301-8.
Title: LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo.
Author: Zhou, Jundong|Zheng, Bing|Ji, Jiansong|Shen, Fei|Min, Han|Liu, Biao|Wu, Jinchang|Zhang, Shuyu
PMID: 25524577
Journal: Biomol Ther (Seoul). 2015 Jan;23(1):39-44.
Title: Tolfenamic Acid Suppresses Inflammatory Stimuli-Mediated Activation of NF-kappaB Signaling.
Author: Shao, Hong Jun|Lou, Zhiyuan|Jeong, Jin Boo|Kim, Kui Jin|Lee, Jihye|Lee, Seong-Ho
PMID: 25593642
Journal: Oncotarget. 2015 Mar 20;6(8):6160-78.
Title: Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFkappaB signaling.
Author: Zhang, Yonggang|Liu, Shu|Wang, Hong|Yang, Wensheng|Li, Fang|Yang, Fan|Yu, Daohai|Ramsey, Frederick V|Tuszyski, George P|Hu, Wenhui
PMID: 25704885
Journal: Nutr Cancer. 2015;67(4):620-36.
Title: Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors.
Author: Saini, Manpreet Kaur|Sanyal, Sankar Nath
PMID: 25825916
Journal: Nutr J. 2015 Apr 1;14:31.
Title: Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells.
Author: Tahir, Analhuda Abdullah|Sani, Nur Fathiah Abdul|Murad, Noor Azian|Makpol, Suzana|Ngah, Wan Zurinah Wan|Yusof, Yasmin Anum Mohd
PMID: 25889965
Journal: Oncotarget. 2015 May 20;6(14):12529-42.
Title: Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-kappaB signaling.
Author: Yang, Yong Ryoul|Kim, Dae Hyun|Seo, Young-Kyo|Park, Dohyun|Jang, Hyun-Jun|Choi, Soo Youn|Lee, Yong Hwa|Lee, Gyun Hui|Nakajima, Kazuki|Taniguchi, Naoyuki|Kim, Jung-Min|Choi, Eun-Jeong|Moon, Hyo Youl|Kim, Il Shin|Choi, Jang Hyun|Lee, Ho|Ryu, Sung Ho|Cocco,
PMID: 25915426
Journal: Oncotarget. 2015 Aug 21;6(24):20288-301.
Title: Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IkappaB.
Author: Muller-Edenborn, Kamila|Leger, Karolin|Glaus Garzon, Jesus F|Oertli, Carole|Mirsaidi, Ali|Richards, Peter J|Rehrauer, Hubert|Spielmann, Patrick|Hoogewijs, David|Borsig, Lubor|Hottiger, Michael O|Wenger, Roland H
PMID: 25978030
Journal: Cancer Sci. 2015 Aug;106(8):1000-7.
Title: Atonal homolog 1 protein stabilized by tumor necrosis factor alpha induces high malignant potential in colon cancer cell line.
Author: Fukushima, Keita|Tsuchiya, Kiichiro|Kano, Yoshihito|Horita, Nobukatsu|Hibiya, Shuji|Hayashi, Ryohei|Kitagaki, Keisuke|Negi, Mariko|Itoh, Eisaku|Akashi, Takumi|Eishi, Yoshinobu|Oshima, Shigeru|Nagaishi, Takashi|Okamoto, Ryuichi|Nakamura, Tetsuya|Watanabe,
PMID: 26017781
Journal: Tumour Biol. 2015 Dec;36(12):9499-510.
Title: Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity.
Author: Wang, Ziyuan|Zhang, Long|Ni, Zhenhua|Sun, Jian|Gao, Hong|Cheng, Zhuoan|Xu, Jianhua|Yin, Peihao
PMID: 26124005
Journal: Planta Med. 2015 Aug;81(12-13):1133-40.
Title: New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis.
Author: Pan, Li|Munoz Acuna, Ulyana|Chai, Heebyung|Park, Hyun-Young|Ninh, Tran Ngoc|Thanh, Bui Van|Merino, Emilio F|Cassera, Maria B|Rakotondraibe, L Harinantenaina|Carcache de Blanco, Esperanza J|Soejarto, Djaja D|Kinghorn, A Douglas
PMID: 26132853
Journal: Oncol Lett. 2015 May;9(5):2135-2142.
Title: Parthenolide induces apoptosis in colitis-associated colon cancer, inhibiting NF-kappaB signaling.
Author: Kim, Se Lim|Liu, Yu Chuan|Seo, Seung Young|Kim, Seong Hun|Kim, In Hee|Lee, Seung Ok|Lee, Soo Teik|Kim, Dae-Ghon|Kim, Sang Wook
PMID: 26137027
Journal: Clin Cancer Res. 2015 Dec 1;21(23):5349-59.
Title: Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-kappaB Pathway.
Author: Liao, Dan|Zhong, Li|Duan, Tingmei|Zhang, Ru-Hua|Wang, Xin|Wang, Gang|Hu, Kaishun|Lv, Xiaobin|Kang, Tiebang
PMID: 26202947
Journal: Oncotarget. 2015 Sep 8;6(26):22869-79.
Title: p53 controls colorectal cancer cell invasion by inhibiting the NF-kappaB-mediated activation of Fascin.
Author: Sui, Xinbing|Zhu, Jing|Tang, Haimei|Wang, Chan|Zhou, Jichun|Han, Weidong|Wang, Xian|Fang, Yong|Xu, Yinghua|Li, Da|Chen, Rui|Ma, Junhong|Jing, Zhao|Gu, Xidong|Pan, Hongming|He, Chao
PMID: 26362504
Journal: Int J Oncol. 2015 Dec;47(6):2276-85.
Title: Chemosensitization by diverging modulation by short-term and long-term TNF-alpha action on ABCB1 expression and NF-kappaB signaling in colon cancer.
Author: Walther, Wolfgang|Kobelt, Dennis|Bauer, Lisa|Aumann, Jutta|Stein, Ulrike
PMID: 26463665
Journal: BMC Cancer. 2015 Oct 23;15:770.
Title: The NF-kappaB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription.
Author: Simon, Priscilla S|Sharman, Sarah K|Lu, Chunwan|Yang, Dafeng|Paschall, Amy V|Tulachan, Sidhartha S|Liu, Kebin
PMID: 26497740
Journal: Invest New Drugs. 2015 Dec;33(6):1175-86.
Title: Identification of a novel compound (beta-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: comparison with curcumin.
Author: Tyagi, Amit Kumar|Prasad, Sahdeo|Yuan, Wei|Li, Shiyou|Aggarwal, Bharat B
PMID: 26521943
Journal: Sci Rep. 2015 Nov 30;5:17348.
Title: Mulberry fruit prevents LPS-induced NF-kappaB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice.
Author: Qian, Zhengjiang|Wu, Zhiqin|Huang, Lian|Qiu, Huiling|Wang, Liyan|Li, Li|Yao, Lijun|Kang, Kang|Qu, Junle|Wu, Yonghou|Luo, Jun|Liu, Johnson J|Yang, Yi|Yang, Wancai|Gou, Deming
PMID: 26615818
Journal: BMC Cancer. 2015 Dec 16;15:974.
Title: Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors.
Author: Li, Xi|Pathi, Satya S|Safe, Stephen
PMID: 26673922
Journal: Int J Cancer Res (Tortola). 2015 Mar;49(1):1655-1662.
Title: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells.
Author: Acuna, Ulyana Munoz|Zi, Jiachen|Orjala, Jimmy|Carcache de Blanco, Esperanza J
PMID: 26753095
Journal: Oncogene. 2016 Feb 4;35(5):549-57.
Title: Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression.
Author: Shvab, A|Haase, G|Ben-Shmuel, A|Gavert, N|Brabletz, T|Dedhar, S|Ben-Ze'ev, A
PMID: 25915847
Journal: Int J Cancer. 2016 Mar 1;138(5):1186-98.
Title: A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation.
Author: Bu, Yiwen|Li, Xiaoning|He, Yingchun|Huang, Chenfei|Shen, Yi|Cao, Yu|Huang, Dan|Cai, Chuan|Wang, Yuhong|Wang, Ziqi|Liao, Duan-Fang|Cao, Deliang
PMID: 26375985
Journal: J Cell Biochem. 2016 Jun;117(6):1471-81.
Title: Evodiamine Suppresses ABCG2 Mediated Drug Resistance by Inhibiting p50/p65 NF-kappaB Pathway in Colorectal Cancer.
Author: Sui, Hua|Zhou, Li-Hong|Zhang, Ya-Li|Huang, Jian-Ping|Liu, Xuan|Ji, Qing|Fu, Xiao-Ling|Wen, Hao-Tian|Chen, Zhe-Sheng|Deng, Wan-Li|Zhu, Hui-Rong|Li, Qi
PMID: 26590365
Journal: Mol Med Rep. 2016 Feb;13(2):1320-8.
Title: L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPARgamma signaling.
Author: Jiang, Fang|Zhang, Zongqi|Zhang, Yi|Wu, Jianping|Yu, Li|Liu, Su
PMID: 26647854
Journal: Int J Oncol. 2016 Apr;48(4):1391-8.
Title: Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-kappaB signal pathway.
Author: Chen, Shaoqin|Chen, Wei|Zhang, Xiang|Lin, Suyong|Chen, Zhihua
PMID: 26847533
Journal: Oncol Lett. 2016 Jan;11(1):267-272.
Title: Differential effect of psoralidin in enhancing apoptosis of colon cancer cells via nuclear factor-kappaB and B-cell lymphoma-2/B-cell lymphoma-2-associated X protein signaling pathways.
Author: Jin, Zhiliang|Yan, Wei|Jin, Hui|Ge, Changzheng|Xu, Yanhua
PMID: 26870201
Journal: Oncotarget. 2016 Apr 5;7(14):17870-84.
Title: Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-beta-catenin axis.
Author: Du, Qianming|Wang, Yajing|Liu, Chao|Wang, Hong|Fan, Huimin|Li, Yan|Wang, Jianing|Zhang, Xu|Lu, Jinrong|Ji, Hui|Hu, Rong
PMID: 26910375
Journal: Oncotarget. 2016 Apr 12;7(15):19794-812.
Title: DDA1 promotes stage IIB-IIC colon cancer progression by activating NFkappaB/CSN2/GSK-3beta signaling.
Author: Zhao, Senlin|Tang, Huamei|Yan, Dongwang|Fan, Junwei|Sun, Hongcheng|Wen, Yugang|Yu, Fudong|Cui, Feifei|Zhang, Dongyuan|Xue, Yingming|Liu, Chenchen|Yue, Ben|Chen, Jian|Wang, Jingtao|Wang, Xiao|Zhang, Meng|Yu, Yang|Jiang, Weiliang|Liu, Xisheng|Mi, Yushuai|Zh
PMID: 26942699
Journal: Neoplasma. 2016;63(3):462-70.
Title: NF-kappaB/p65 expression before and after treatment in rectal cancer patients undergoing neoadjuvant (chemo)radiotherapy and surgery: prognostic marker for disease progression and survival.
Author: Voboril, R|Rychterova, V|Voborilova, J|Kubecova, M|Fanta, J|Dvorak, J
PMID: 26952512
Journal: Exp Ther Med. 2016 Mar;11(3):1085-1089.
Title: Tanshinone IIA enhances chemosensitivity of colon cancer cells by suppressing nuclear factor-kappaB.
Author: Bai, Yangqiu|Zhang, Lida|Fang, Xinhui|Yang, Yuxiu
PMID: 26998041
Journal: Onco Targets Ther. 2016 Feb 29;9:1011-21.
Title: Overexpression of Livin promotes migration and invasion of colorectal cancer cells by induction of epithelial-mesenchymal transition via NF-kappaB activation.
Author: Ge, Yang|Cao, Xiankui|Wang, Dalu|Sun, Wei|Sun, Hongli|Han, Bing|Cui, Junpeng|Liu, Baolin
PMID: 27013894
Journal: Mediators Inflamm. 2016;2016:2853040.
Title: GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-kappaB Pathway.
Author: Wang, Yajing|Lu, Ping|Zhang, Weifeng|Du, Qianming|Tang, Jingjing|Wang, Hong|Lu, Jinrong|Hu, Rong
PMID: 27057094
Journal: Anticancer Res. 2016 Apr;36(4):1631-9.
Title: NFkappaB-Associated Pathways in Progression of Chemoresistance to 5-Fluorouracil in an In Vitro Model of Colonic Carcinoma.
Author: Korber, Maria Isabel|Staribacher, Anna|Ratzenbock, Ina|Steger, Gunther|Mader, Robert M
PMID: 27069140
Journal: Oncol Res. 2016;23(5):249-56.
Title: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression.
Author: Ren, Hongtao|Wang, Zhongwei|Zhang, Shuqun|Ma, Hongbing|Wang, Yali|Jia, Lijun|Li, Yiming
PMID: 27098148
Journal: World J Gastroenterol. 2016 Apr 21;22(15):3969-77.
Title: Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells.
Author: Shen, Hong|Ma, Jun-Li|Zhang, Yan|Deng, Gan-Lu|Qu, Yan-Ling|Wu, Xiao-Ling|He, Jing-Xuan|Zhang, Sai|Zeng, Shan
PMID: 27099440
Journal: Oncotarget. 2016 Jun 14;7(24):36551-36562.
Title: Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer.
Author: Ma, Juan|Mi, Chunliu|Wang, Ke Si|Lee, Jung Joon|Jin, Xuejun
PMID: 27144516
Journal: Clin Lab. 2016;62(3):463-9.
Title: STC1 and NF-kappaB p65 (Rel A) is Constitutively Activated in Colorectal Cancer.
Author: Rezapour, Saleheh|Bahrami, Tayyeb|Hashemzadeh, Shahryar|Estiar, Mehrdad Asghari|Nemati, Masoumeh|Ravanbakhsh, Reyhaneh|Feizi, Mohammad Ali Hosseinpour|Kafil, Hossein Samadi|Pouladi, Nasser|Ghojazadeh, Morteza|Sakhinia, Ebrahim
PMID: 27156337
Journal: Am J Transl Res. 2016 Feb 15;8(2):842-59. eCollection 2016.
Title: Identification and verification of PRDX1 as an inflammation marker for colorectal cancer progression.
Author: Chu, Guanghui|Li, Juntang|Zhao, Yali|Liu, Ningning|Zhu, Xiaoshan|Liu, Qinqin|Wei, Dong|Gao, Chunfang
PMID: 27158373
Journal: Arch Biochem Biophys. 2016 Aug 15;604:20-6.
Title: IL-1beta/NF-kb signaling promotes colorectal cancer cell growth through miR-181a/PTEN axis.
Author: Hai Ping, Pei|Feng Bo, Tan|Li, Liu|Nan Hui, Yu|Hong, Zhu
PMID: 27264420
Journal: Int J Oncol. 2016 Aug;49(2):629-38.
Title: 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-kappaB activation.
Author: Lin, Chien-Liang|Hsieh, Shu-Ling|Leung, Wan|Jeng, Jiiang-Huei|Huang, Guan-Cheng|Lee, Chining-Ting|Wu, Chih-Chung
PMID: 27278328
Journal: Pharmacogn Mag. 2016 May;12(Suppl 2):S237-44.
Title: Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco-2 Cells Through Regulating Toll-like Receptor 4/Nuclear Factor-kappa B Pathway.
Author: Han, Mingyang|Song, Yucheng|Zhang, Xuedong
PMID: 27279714
Journal: Oncotarget. 2016 Jun 28;7(26):40704-40718.
Title: Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/beta-catenin signaling.
Author: Liu, Dan|Du, Lei|Chen, Dong|Ye, Zhongde|Duan, Hongxia|Tu, Tao|Feng, Jing|Yang, Yili|Chen, Quan|Yan, Xiyun
PMID: 27302922
Journal: Cancer Lett. 2016 Sep 28;380(1):87-97.
Title: Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis.
Author: Lu, Yun-Xin|Ju, Huai-Qiang|Wang, Feng|Chen, Le-Zong|Wu, Qi-Nian|Sheng, Hui|Mo, Hai-Yu|Pan, Zhi-Zhong|Xie, Dan|Kang, Tie-Bang|Chen, Gong|Yun, Jing-Ping|Zeng, Zhao-Lei|Xu, Rui-Hua
PMID: 27322737
Journal: J Surg Oncol. 2016 Sep;114(4):520-7.
Title: Knockdown of NDRG1 promote epithelial-mesenchymal transition of colorectal cancer via NF-kappaB signaling.
Author: Ma, Junli|Gao, Quanli|Zeng, Shan|Shen, Hong
PMID: 27338835
Journal: Mol Cancer Res. 2016 Sep;14(9):795-804.
Title: Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development.
Author: Mo, Allen|Jackson, Stephen|Varma, Kamini|Carpino, Alan|Giardina, Charles|Devers, Thomas J|Rosenberg, Daniel W
PMID: 27353028
Journal: Oncol Rep. 2016 Sep;36(3):1333-8.
Title: Oxymatrine inhibits epithelial-mesenchymal transition through regulation of NF-kappaB signaling in colorectal cancer cells.
Author: Liang, Li|Huang, Jiean
PMID: 27430890
Journal: Protein Cell. 2016 Aug;7(8):571-85.
Title: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author: Shan, Jianzhen|Xuan, Yanyan|Zhang, Qi|Zhu, Chunpeng|Liu, Zhen|Zhang, Suzhan
PMID: 27472952
Journal: Int J Cancer. 2016 Dec 1;139(11):2553-69.
Title: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.
Author: Xia, Jianling|Huang, Na|Huang, Hongxiang|Sun, Li|Dong, Shaoting|Su, Jinyu|Zhang, Jingwen|Wang, Lin|Lin, Li|Shi, Min|Bin, Jianping|Liao, Yulin|Li, Nailin|Liao, Wangjun
PMID: 27529686
Journal: Oncotarget. 2016 Sep 27;7(39):63342-63351.
Title: Rab27A mediated by NF-kappaB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion.
Author: Feng, Feixue|Jiang, Yinghao|Lu, Huanyu|Lu, Xiaozhao|Wang, Shan|Wang, Lifeng|Wei, Mengying|Lu, Wei|Du, Zhichao|Ye, Zichen|Yang, Guodong|Yuan, Fang|Ma, Yanxia|Lei, Xiaoying|Lu, Zifan
PMID: 27556511
Journal: Br J Cancer. 2016 Sep 27;115(7):814-24.
Title: gamma-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules.
Author: Prasad, Sahdeo|Gupta, Subash C|Tyagi, Amit K|Aggarwal, Bharat B
PMID: 27575851
Journal: Oncotarget. 2016 Sep 20;7(38):62559-62571.
Title: Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation.
Author: Jung, Sung-Hoon|Kim, Su-Min|Lee, Choong-Eun
PMID: 27613835
Journal: Oncoimmunology. 2016 Jun 29;5(7):e1149667.
Title: Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.
Author: Millen, Rosemary|Malaterre, Jordane|Cross, Ryan S|Carpinteri, Sandra|Desai, Jayesh|Tran, Ben|Darcy, Phillip|Gibbs, Peter|Sieber, Oliver|Zeps, Nikolajs|Waring, Paul|Fox, Stephen|Pereira, Lloyd|Ramsay, Robert G
PMID: 27622014
Journal: Front Pharmacol. 2016 Sep 13;7:311.
Title: Vam3, a Compound Derived from Vitis amurensis Rupr., Attenuated Colitis-Related Tumorigenesis by Inhibiting NF-kappaB Signaling Pathway.
Author: Xuan, Lingling|Jiang, Rentao|Wu, Zhiyuan|Yi, Honggan|Yao, Chunsuo|Hou, Qi|Qu, Chunfeng
PMID: 27679575
Journal: PLoS One. 2016 Sep 29;11(9):e0163209.
Title: Novel Synthetic Oxazines Target NF-kappaB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo.
Author: Nirvanappa, Anilkumar C|Mohan, Chakrabhavi Dhananjaya|Rangappa, Shobith|Ananda, Hanumappa|Sukhorukov, Alexey Yu|Shanmugam, Muthu K|Sundaram, Mahalingam S|Nayaka, Siddaiah Chandra|Girish, Kesturu S|Chinnathambi, Arunachalam|Zayed, M E|Alharbi, Sulaiman Ali
PMID: 27685808
Journal: Oncol Lett. 2016 Oct;12(4):2840-2845.
Title: Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-kappaB.
Author: Zhang, Lida|Bai, Yangqiu|Yang, Yuxiu
PMID: 27698868
Journal: BMC Cancer. 2016 Oct 12;16(1):791.
Title: Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
Author: Ding, Chenbo|Li, Longmei|Yang, Taoyu|Fan, Xiaobo|Wu, Guoqiu
PMID: 27729020
Journal: Biochem Biophys Res Commun. 2016 Nov 25;480(4):528-533.
Title: microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells.
Author: Sathyanarayanan, Anusha|Chandrasekaran, Karthik Subramanian|Karunagaran, Devarajan
PMID: 27769860
Journal: Food Funct. 2016 Dec 7;7(12):4797-4803.
Title: The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-kappaB signaling pathway.
Author: Hsieh, Shu-Chen|Hsieh, Wang-Ju|Chiang, An-Na|Su, Nan-Wei|Yeh, Yu-Te|Liao, Yi-Chun
PMID: 27869910
Journal: Onco Targets Ther. 2016 Dec 14;9:7563-7571.
Title: Lipopolysaccharide-induced alpha-catenin downregulation enhances the motility of human colorectal cancer cells in an NF-kappaB signaling-dependent manner.
Author: Cheng, Guoping|Yang, Shifeng|Zhang, Gu|Xu, Yanxia|Liu, Xiaoling|Sun, Wenyong|Zhu, Liang
PMID: 28008274
Journal: J Proteomics Bioinform. 2016 Oct;9(10):238-247.
Title: Protein Markers Associated with an ALDH Sub-Population in Colorectal Cancer.
Author: Yang, Rui|Liu, Xinhua|Thakolwiboon, Smathorn|Zhu, Jianhui|Pei, Xiucong|An, Mingrui|Tan, Zhijing|Lubman, David M
PMID: 28503055
Journal: J Pineal Res. 2017 Mar;62(2).
Title: Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-kappaB/iNOS signaling pathways.
Author: Gao, Yue|Xiao, Xiangsheng|Zhang, Changlin|Yu, Wendan|Guo, Wei|Zhang, Zhifeng|Li, Zhenglin|Feng, Xu|Hao, Jiaojiao|Zhang, Kefang|Xiao, Bingyi|Chen, Miao|Huang, Wenlin|Xiong, Shunbin|Wu, Xiaojun|Deng, Wuguo
PMID: 27865009
Journal: Cancer Biol Ther. 2017 Apr 3;18(4):257-267.
Title: Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer.
Author: Saxena, Arpit|Fayad, Raja|Kaur, Kamaljeet|Truman, Samantha|Greer, Julian|Carson, James A|Chanda, Anindya
PMID: 28045589
Journal: PLoS One. 2017 Jan 26;12(1):e0170595.
Title: Knockdown of NIK and IKKbeta-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF-kappaBeta Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.
Author: Qin, Mengbin|Zhang, Jinxiu|Xu, Chunyan|Peng, Peng|Tan, Lin|Liu, Shiquan|Huang, Jiean
PMID: 28125661
Journal: Mol Cancer. 2017 Feb 1;16(1):30.
Title: Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
Author: Chandrakesan, Parthasarathy|Yao, Jiannan|Qu, Dongfeng|May, Randal|Weygant, Nathaniel|Ge, Yang|Ali, Naushad|Sureban, Sripathi M|Gude, Modhi|Vega, Kenneth|Bannerman-Menson, Eddie|Xia, Lijun|Bronze, Michael|An, Guangyu|Houchen, Courtney W
PMID: 28148261
Journal: Biochimie. 2017 Apr;135:154-163.
Title: Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells.
Author: Mohamad Fairus, A K|Choudhary, B|Hosahalli, S|Kavitha, N|Shatrah, O
PMID: 28196676
Journal: Cell Biol Int. 2017 May;41(5):555-569.
Title: Identification of novel NF-kappaB transcriptional targets in TNFalpha-treated HeLa and HepG2 cells.
Author: Zhou, Fei|Xu, Xinhui|Wang, Danyang|Wu, Jian|Wang, Jinke
PMID: 28276104
Journal: United European Gastroenterol J. 2017 Mar;5(2):218-226.
Title: A PPAR-gamma agonist protects from radiation-induced intestinal toxicity.
Author: Mangoni, Monica|Sottili, Mariangela|Gerini, Chiara|Desideri, Isacco|Bastida, Cinzia|Pallotta, Stefania|Castiglione, Francesca|Bonomo, Pierluigi|Meattini, Icro|Greto, Daniela|Cappelli, Sabrina|Di Brina, Lucia|Loi, Mauro|Biti, Giampaolo|Livi, Lorenzo
PMID: 28344789
Journal: Tumour Biol. 2017 Mar;39(3):1010428317695962.
Title: Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment.
Author: Zou, Kejian|Wang, Yaodong|Hu, Yan|Zheng, Liansheng|Xu, Wanfu|Li, Guoxin
PMID: 28347237
Journal: Oncotarget. 2017 Jul 4;8(27):44694-44704.
Title: FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells.
Author: Liu, Shuo|Zhang, Cun|Zhang, Kuo|Gao, Yuan|Wang, Zhaowei|Li, Xiaoju|Cheng, Guang|Wang, Shuning|Xue, Xiaochang|Li, Weina|Zhang, Wei|Zhang, Yingqi|Xing, Xianghui|Li, Meng|Hao, Qiang
PMID: 28591725
Journal: Alcohol. 2017 Jun;61:25-31.
Title: Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats.
Author: Klarich, DawnKylee S|Penprase, Jerrold|Cintora, Patricia|Medrano, Octavio|Erwin, Danielle|Brasser, Susan M|Hong, Mee Young
PMID: 28599714
Journal: Cancer Chemother Pharmacol. 2017 Aug;80(2):395-403.
Title: Visfatin mediates doxorubicin resistance in human colorectal cancer cells via up regulation of multidrug resistance 1 (MDR1).
Author: Yan, Xiaofei|Zhao, Jian|Zhang, Rui
PMID: 28667355
Journal: World J Gastroenterol. 2017 Jun 28;23(24):4341-4353.
Title: Indole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells.
Author: Tischlerova, Viera|Kello, Martin|Budovska, Mariana|Mojzis, Jan
PMID: 28706417
Journal: J Agric Food Chem. 2017 Aug 23;65(33):7200-7209.
Title: Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice.
Author: Wu, Xian|Pfalzer, Anna C|Koh, Gar Yee|Tang, Sanyuan|Crott, Jimmy W|Thomas, Michael J|Meydani, Mohsen|Mason, Joel B
PMID: 28745498
Journal: Acta Biochim Pol. 2017;64(3):567-576.
Title: Flavanols from Japanese quince (Chaenomeles japonica) fruit suppress expression of cyclooxygenase-2, metalloproteinase-9, and nuclear factor-kappaB in human colon cancer cells.
Author: Owczarek, Katarzyna|Hrabec, Elzbieta|Fichna, Jakub|Sosnowska, Dorota|Koziolkiewicz, Maria|Szymanski, Jacek|Lewandowska, Urszula
PMID: 28787469
Journal: Br J Cancer. 2017 Oct 10;117(8):1164-1175.
Title: FMNL2 destabilises COMMD10 to activate NF-kappaB pathway in invasion and metastasis of colorectal cancer.
Author: Yang, S S|Li, X M|Yang, M|Ren, X L|Hu, J L|Zhu, X H|Wang, F F|Zeng, Z C|Li, J Y|Cheng, Z Q|Liao, W T|Ding, Y Q|Guan, J|Liang, L
PMID: 28817833
Journal: Oncol Rep. 2017 Nov;38(5):2619-2628.
Title: alpha7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway.
Author: Fei, Rushan|Zhang, Yuanwei|Wang, Saisai|Xiang, Tao|Chen, Wenbin
PMID: 28901507
Journal: Cell Death Differ. 2017 Dec;24(12):2199-2209.
Title: miR-148a inhibits colitis and colitis-associated tumorigenesis in mice.
Author: Zhu, Yahui|Gu, Li|Li, Yajun|Lin, Xi|Shen, Hongxing|Cui, Kaisa|Chen, Li|Zhou, Feng|Zhao, Qiu|Zhang, Jinxiang|Zhong, Bo|Prochownik, Edward|Li, Youjun
PMID: 28960206
Journal: Cell Commun Signal. 2017 Oct 10;15(1):39.
Title: NF-kappaB potentiates tumor growth by suppressing a novel target LPTS.
Author: Liu, Dongbo|Miao, Hongping|Zhao, Yuanyin|Kang, Xia|Shang, Shenglan|Xiang, Wei|Shi, Rongchen|Hou, Along|Wang, Rui|Zhao, Kun|Liu, Yingzhe|Ma, Yue|Luo, Huan|Miao, Hongming|He, Fengtian
PMID: 29017500
Journal: Nat Commun. 2017 Oct 16;8(1):939.
Title: PKCepsilon phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation.
Author: Chen, Tao|Li, Jingjie|Xu, Meidong|Zhao, Qin|Hou, Yingyong|Yao, Liqing|Zhong, Yunshi|Chou, Ping-Chieh|Zhang, Wei|Zhou, Pinghong|Jiang, Yuhui
PMID: 29038521
Journal: Oncol Lett. 2017 Nov;14(5):5540-5548.
Title: Pteisolic acid G, a novel ent-kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells.
Author: Qiu, Shuangli|Wu, Xin|Liao, Hongbo|Zeng, Xiaobin|Zhang, Senwang|Lu, Xiaofen|He, Xiaohong|Zhang, Xiaoqi|Ye, Wencai|Wu, Hua|Zhu, Xiaohui
PMID: 29113182
Journal: Anticancer Agents Med Chem. 2017 Dec 13. pii: ACAMC-EPUB-87383.
Title: The effect of flubendazole on adhesion and migration in SW480 and SW620 colon cancer cells.
Author: Hanusova, Veronika|Skalova, Lenka|Kralova, Vera|Matouskova, Petra
PMID: 29237383
Journal: BMC Complement Altern Med. 2017 Dec 16;17(1):538.
Title: Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer.
Author: Li, Hai|Chen, Chen
PMID: 29246220
Journal: Oncotarget. 2017 Dec 4;8(67):111597-111607.
Title: LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)-Mdm2-P53-dependent cellular senescence.
Author: Wang, Haibin|Xu, Guoxing|Huang, Zhengjie|Li, Weizheng|Cai, Huali|Zhang, Yunda|Xiong, Disheng|Liu, Gang|Wang, Shengjie|Xue, Zengfu|Luo, Qi
PMID: 29340077
Journal: Pharmazie. 2017 Aug 1;72(8):475-481.
Title: microRNA-335 inhibits colorectal cancer HCT116 cells growth and epithelial-mesenchymal transition (EMT) process by targeting Twist1.
Author: Wang, Jingyuan|Wang, Xuemei|Liu, Fengjun|Fu, Yuguang
PMID: 29441907
Journal: Int J Biol Macromol. 2018 Apr 1;109:212-219.
Title: The toxin BjussuLAAO-II induces oxidative stress and DNA damage, upregulates the inflammatory cytokine genes TNF and IL6, and downregulates the apoptotic-related genes BAX, BCL2 and RELA in human Caco-2 cells.
Author: Machado, A R T|Aissa, A F|Ribeiro, D L|Hernandes, L C|Machado, C S|Bianchi, M L P|Sampaio, S V|Antunes, L M G
PMID: 29222016
Journal: Int J Mol Med. 2018 Mar;41(3):1305-1314.
Title: Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-kappaB signaling pathway.
Author: Luan, Yunpeng|Li, Yanmei|Zhu, Lina|Zheng, Shuangqing|Mao, Dechang|Chen, Zhuxue|Cao, Yong
PMID: 29286074
Journal: Cell Death Dis. 2018 Jan 19;9(2):44.
Title: Insight into the role of PIKK family members and NF-small ka, CyrillicB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.
Author: Strzeszewska, Anna|Alster, Olga|Mosieniak, Grazyna|Ciolko, Agata|Sikora, Ewa
PMID: 29352261
Journal: Clin Cancer Res. 2018 Apr 15;24(8):2015-2025.
Title: REGgamma Controls Hippo Signaling and Reciprocal NF-kappaB-YAP Regulation to Promote Colon Cancer.
Author: Wang, Qingwei|Gao, Xiao|Yu, Tong|Yuan, Lei|Dai, Jie|Wang, Weicang|Chen, Geng|Jiao, Chan|Zhou, Wang|Huang, Quan|Cui, Long|Zhang, Pei|Moses, Robb E|Yang, Jianhua|Chen, Fengyuan|Fu, Junjiang|Xiao, Jianru|Li, Lei|Dang, Yongyan|Li, Xiaotao
PMID: 29437787
Journal: Nutrients. 2018 Feb 12;10(2). pii: nu10020202.
Title: Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice.
Author: Chung, Kyung-Sook|Cheon, Se-Yun|Roh, Seong-Soo|Lee, Minho|An, Hyo-Jin
PMID: 29439531
Journal: Cancer Sci. 2018 Apr;109(4):1220-1229.
Title: Antimalarial drug mefloquine inhibits nuclear factor kappa B signaling and induces apoptosis in colorectal cancer cells.
Author: Xu, Xin|Wang, Jun|Han, Kunkun|Li, Shaoyan|Xu, Feng|Yang, Yili
PMID: 29453896
Journal: Int Immunopharmacol. 2018 Apr;57:82-90.
Title: Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-kappaB and MAPK signalling pathways.
Author: Gao, Zhenfang|Yu, Cuicui|Liang, Haiyue|Wang, Xuekai|Liu, Yue|Li, Xin|Ji, Kai|Xu, Hui|Yang, Mingyan|Liu, Ke|Qi, Dong|Fan, Huaying
PMID: 29475099
Journal: Oncogene. 2018 May;37(22):3006-3021.
Title: DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients.
Author: Tang, Jieting|Chen, Huarong|Wong, Chi-Chun|Liu, Dabin|Li, Tong|Wang, Xiaohong|Ji, Jiafu|Sung, Joseph Jy|Fang, Jing-Yuan|Yu, Jun
PMID: 29535419
Journal: J Pathol. 2018 Jun;245(2):222-234.
Title: Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers.
Author: Ye, Wen|Ling, Shaoping|Liu, Ran-Yi|Pan, Zhi-Zhong|Wang, Gaoyuan|Gao, Shijuan|Wu, Jiangxue|Cao, Lihua|Dong, Lili|Li, Yingchang|Zhou, Yi|Du, Wuying|Meng, Xiangqi|Chen, Jinna|Guan, Xinyuan|He, Yulong|Pan, Changchuan|Zheng, Xf Steven|Lu, Xuemei|Chen, Shuai|Hu
PMID: 29537081
Journal: Oncol Lett. 2018 Apr;15(4):5465-5472.
Title: Expression of factors and key components associated with the PI3K signaling pathway in colon cancer.
Author: Chen, Hua|Gao, Junyi|Du, Zhenhua|Zhang, Xuequn|Yang, Fei|Gao, Wei
PMID: 29552187
Journal: BMC Complement Altern Med. 2018 Jan 25;18(1):28.
Title: Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells.
Author: Park, Gwang Hun|Song, Hun Min|Park, Su Bin|Son, Ho-Jun|Um, Yurry|Kim, Hyun-Seok|Jeong, Jin Boo
PMID: 29554905
Journal: Oncotarget. 2018 Mar 23;9(22):15952-15967.
Title: Uev1A-Ubc13 promotes colorectal cancer metastasis through regulating CXCL1 expression via NF-small ka, CyrillicB activation.
Author: Wu, Zhaojia|Neufeld, Heather|Torlakovic, Eminao|Xiao, Wei
PMID: 29662619
Journal: Cancer Chemother Pharmacol. 2018 Jun;81(6):1111-1119.
Title: IL-8 regulates the doxorubicin resistance of colorectal cancer cells via modulation of multidrug resistance 1 (MDR1).
Author: Du, Jing|He, Yuanqiao|Li, Peng|Wu, Weiquan|Chen, Youwei|Ruan, Hongjun
PMID: 29693201
Journal: Oncol Lett. 2018 May;15(5):7716-7724.
Title: Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-kappaB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.
Author: Juan, Ta-Kuo|Liu, Kuo-Ching|Kuo, Chao-Lin|Yang, Mei-Due|Chu, Yung-Lin|Yang, Jiun-Long|Wu, Ping-Ping|Huang, Yi-Ping|Lai, Kuang-Chi|Chung, Jing-Gung
PMID: 29731901
Journal: J Agric Food Chem. 2018 Jun 6;66(22):5563-5573.
Title: Vanillin-Ameliorated Development of Azoxymethane/Dextran Sodium Sulfate-Induced Murine Colorectal Cancer: The Involvement of Proteasome/Nuclear Factor-kappaB/Mitogen-Activated Protein Kinase Pathways.
Author: Li, Jung-Miao|Lee, Yu-Chen|Li, Chia-Cheng|Lo, Hsin-Yi|Chen, Feng-Yuan|Chen, Yi-Siou|Hsiang, Chien-Yun|Ho, Tin-Yun
PMID: 29790745
Journal: Int J Oncol. 2018 Aug;53(2):781-790.
Title: Let7d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway.
Author: Jiang, Jie|Liu, Hui-Ling|Tao, Li|Lin, Xian-Yi|Yang, Yi-Dong|Tan, Si-Wei|Wu, Bin
PMID: 29845224
Journal: Oncol Lett. 2018 May;15(5):7344-7354.
Title: Expression profile of NF-kappaB regulated genes in sporadic colorectal cancer patients.
Author: Gonzalez-Quezada, Betsy Annel|Santana-Bejarano, Uriel Francisco|Corona-Rivera, Alfredo|Pimentel-Gutierrez, Helia Judith|Silva-Cruz, Rocio|Ortega-De-la-Torre, Citlalli|Franco-Topete, Ramon|Franco-Topete, Karina|Centeno-Flores, Manuel Willebaldo|Maciel-Guti
PMID: 29849793
Journal: In Vitro Cell Dev Biol Anim. 2018 Aug;54(7):505-512.
Title: L-carnosine induces apoptosis/cell cycle arrest via suppression of NF-kappaB/STAT1 pathway in HCT116 colorectal cancer cells.
Author: Lee, Jooyeon|Park, Jeong-Ran|Lee, Hanbyeol|Jang, Soojin|Ryu, Se-Min|Kim, Hyejin|Kim, Donguk|Jang, Aera|Yang, Se-Ran
PMID: 29869056
Journal: J Clin Biochem Nutr. 2018 May;62(3):221-229.
Title: Augmented O-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation.
Author: Hirata, Yoshimasa|Nakagawa, Takatoshi|Moriwaki, Kazumasa|Koubayashi, Eiko|Kakimoto, Kazuki|Takeuchi, Toshihisa|Inoue, Takuya|Higuchi, Kazuhide|Asahi, Michio
PMID: 29892160
Journal: Oncol Rep. 2018 Sep;40(3):1533-1544.
Title: Pin2/TRF1binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factorkappaB signaling pathway.
Author: Jiang, Tao|Li, Haiqing|Jiang, Ranran|Li, Hailong|Hou, Pingfu|Chen, Yansu|Bai, Jin|Song, Jun
PMID: 30015978
Journal: Cell Death Dis. 2018 Aug 6;9(8):838.
Title: CiRS-7 promotes growth and metastasis of esophageal squamous cell carcinoma via regulation of miR-7/HOXB13.
Author: Li, Rui-Chao|Ke, Shun|Meng, Fan-Kai|Lu, Jun|Zou, Xiao-Jing|He, Zhi-Gang|Wang, Weng-Feng|Fang, Ming-Hao
PMID: 30082829
Journal: Oncol Lett. 2018 Oct;16(4):4439-4447.
Title: Butyrate upregulates the TLR4 expression and the phosphorylation of MAPKs and NK-kappaB in colon cancer cell in vitro.
Author: Xiao, Tengfei|Wu, Shuiyun|Yan, Cheng|Zhao, Chuanxiang|Jin, Huimin|Yan, Nannan|Xu, Jie|Wu, Yi|Li, Ci|Shao, Qixiang|Xia, Sheng
PMID: 30214578
Journal: Cancer Med. 2018 Sep 28.
Title: GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF-kappaB signaling pathway in colorectal cancer cells.
Author: Zhang, Zhongqiang|Tan, Xiao|Luo, Jing|Cui, Beibei|Lei, Sanlin|Si, Zhongzhou|Shen, Liangfang|Yao, Hongliang
PMID: 30267476
Journal: Nutr Cancer. 2018 Oct 1:1-10.
Title: Triticum aestivum Sprouts Extract Inhibits Azoymethane (AOM)/Dextran Sodium Sulfate (DSS)-Induced Colon Carcinogenesis in Mice.
Author: Ki, Hyeon-Hui|Lee, Ji-Hyun|Lee, Hoon-Yeon|Lee, Young-Mi|Kim, Dae-Ki
PMID: 30273050
Journal: IUBMB Life. 2018 Nov;70(11):1093-1100.
Title: Long noncoding RNA FAL1 promotes proliferation and inhibits apoptosis of human colon cancer cells.
Author: Wu, Kaiming|Zhang, Ning|Ma, Jun|Huang, Jiehong|Chen, Jianhui|Wang, Liang|Zhang, Jian
PMID: 30290064
Journal: Indian J Clin Biochem. 2018 Oct;33(4):473-478.
Title: Increased Nuclear Factor-kappaB/RelA Expression Levels in Human Colorectal Carcinoma in North Indian Patients.
Author: Negi, Ram Rattan|Rana, Satya Vati|Gupta, Rajesh|Gupta, Vikas|Chadha, Vijayta D|Dhawan, Devinder K
PMID: 30319196
Journal: Int Immunopharmacol. 2018 Oct 12;65:221-232.
Title: Restoration of stemness-high tumor cell-mediated suppression of murine dendritic cell activity and inhibition of tumor growth by low molecular weight oyster polysaccharide.
Author: Zhong, Ming|Zhong, Cheng|Hu, Pei|Cui, Wen|Wang, Guanghui|Gao, Huijei|Liu, Chao|Liu, Zhiqiang|Li, Zhihua|Li, Chunxia|Gohda, Eiichi
PMID: 30321818