Primary Site >> Colorectal Cancer
Gene >> RELA
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Ref: The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines. PMID: 8311838 |
Ref: Down-regulation of NF-kappaB activity and NF-kappaB p65 subunit expression by ras and polyoma middle T oncogenes in human colonic Caco-2 cells. PMID: 9129150 |
Ref: Two proteins share immunological epitopes on the tumor-associated antigen 17-1A. PMID: 10503883 |
Ref: Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line. PMID: 10903137 Ref: IkappaBbeta-related proteins in normal and transformed colonic epithelial cells. PMID: 11020244 |
Ref: Cellular protein alterations in colorectal cancer: p28, p53 and p65 studies. PMID: 11534828 |
Ref: [Activation of nuclear factor-kappaB and effects of anti-inflammatory treatment thereon in intestinal mucosa of patients with ulcerative colitis]. PMID: 11953203 Ref: PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway. PMID: 12360479 Ref: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. PMID: 12507930 |
Ref: Antineoplastic therapy in colorectal cancer through proteasome inhibition. PMID: 12575774 Ref: Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer. PMID: 12727794 Ref: Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis. PMID: 12837981 Ref: Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. PMID: 12839952 Ref: NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells. PMID: 12934082 Ref: Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. PMID: 14520472 Ref: Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta. PMID: 14587029 |
Ref: Increased expression of nuclear factor-kappaB/RelA is correlated with tumor angiogenesis in human colorectal cancer. PMID: 12827408 Ref: Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer. PMID: 15013430 Ref: Expression of the p65 gene in patients with colorectal cancer: comparison with some histological typing, grading and clinical staging. PMID: 15028307 Ref: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8]. PMID: 15034288 Ref: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling. PMID: 15047705 Ref: Nuclear factor-kappa B regulates cyclooxygenase-2 expression and cell proliferation in human colorectal carcinoma tissue. PMID: 15112579 Ref: Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. PMID: 15161687 Ref: Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer. PMID: 15234907 Ref: Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation. PMID: 15254665 Ref: Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue. PMID: 15484295 |
Ref: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK. PMID: 15611081 Ref: Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation. PMID: 15618021 Ref: Selenomethionine regulates cyclooxygenase-2 (COX-2) expression through nuclear factor-kappa B (NF-kappaB) in colon cancer cells. PMID: 15655349 Ref: Synergy between deacetylase inhibitors and IL-1beta in activation of the serum amyloid A2 gene promoter. PMID: 15812237 Ref: Diclofenac attenuates Wnt/beta-catenin signaling in colon cancer cells by activation of NF-kappaB. PMID: 16051228 |
Ref: Nuclear factor kappaB is downregulated and correlates with p53 in the Min mouse mucosa during an accelerated tumor growth. PMID: 16049962 Ref: Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells. PMID: 16106402 Ref: Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. PMID: 16360644 Ref: Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress. PMID: 16401637 Ref: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. PMID: 16448212 Ref: Inhibition of NF-kappaB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells. PMID: 16465375 Ref: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. PMID: 16497702 Ref: Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. PMID: 16619535 Ref: Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. PMID: 16637064 |
Ref: Aspirin activates the NF-kappaB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer. PMID: 17132819 Ref: Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells. PMID: 17186550 Ref: p38-mediated inactivation of cyclin D1/cyclin-dependent kinase 4 stimulates nucleolar translocation of RelA and apoptosis in colorectal cancer cells. PMID: 17308107 Ref: TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response. PMID: 17373661 Ref: CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA. PMID: 17525529 Ref: [NF-kappaB, colorectal carcinoma and radiotherapy: results of a clinical and experimental study]. PMID: 17634017 Ref: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death. PMID: 17671207 Ref: Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition. PMID: 17699782 Ref: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. PMID: 17868752 Ref: Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway. PMID: 17938270 Ref: Sensitization of colorectal cancer cells to irradiation by IL-4 and IL-10 is associated with inhibition of NF-kappaB. PMID: 17949233 Ref: Quantitative analysis of the p65 gene expression in patients with coloroctal cancer. PMID: 23675055 |
Ref: The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB. PMID: 18059344 Ref: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. PMID: 18241858 Ref: Dissociated invasively growing cancer cells with NF-kappaB/p65 positivity after radiotherapy: a new marker for worse clinical outcome in rectal cancer? Preliminary data. PMID: 18324356 Ref: Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kappaB in HCT116 colon cancer cells. PMID: 18575716 Ref: [Expression of nuclear factor-kappa-B/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof]. PMID: 18646716 Ref: NF-kappaB-dependency and consequent regulation of IL-8 in echinomycin-induced apoptosis of HT-29 colon cancer cells. PMID: 18675368 Ref: [Immunohistochemical analysis of nuclear factor, p38, and cyclin D1 proteins in premalignant lesions and carcinomas of the colorectal mucosa]. PMID: 19096253 Ref: Evaluation of the expression of transcriptional factor NF-kappaB induced by phytic acid in colon cancer cells. PMID: 19172851 |
Ref: Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer. PMID: 18752053 Ref: High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. PMID: 18825388 Ref: Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells. PMID: 19121919 Ref: Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling. PMID: 19159619 Ref: Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells. PMID: 19383900 Ref: Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue. PMID: 19513071 Ref: An anti-inflammatory mechanism of taurine conjugated 5-aminosalicylic acid against experimental colitis: taurine chloramine potentiates inhibitory effect of 5-aminosalicylic acid on IL-1beta-mediated NFkappaB activation. PMID: 19616541 Ref: Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells. PMID: 19826421 Ref: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). PMID: 19839614 |
Ref: Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. PMID: 20061362 Ref: Bioactivity-guided isolation of cytotoxic sesquiterpenes of Rolandra fruticosa. PMID: 20189206 Ref: Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida. PMID: 20384315 Ref: NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer. PMID: 20414006 Ref: Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells. PMID: 20501702 Ref: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. PMID: 20509140 Ref: Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression. PMID: 20558745 Ref: NO-releasing NSAIDs suppress NF-kappaB signaling in vitro and in vivo through S-nitrosylation. PMID: 20674154 Ref: Quantitative evaluation of transcriptional activation of NF-kappaB p65 and p50 subunits and IkappaBalpha encoding genes in colon cancer cells by Desulfovibrio desulfuricans endotoxin. PMID: 21253915 Ref: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells. PMID: 21713362 |
Ref: Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. PMID: 19876598 Ref: NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). PMID: 20715105 Ref: Sage components enhance cell death through nuclear factor kappa-B signaling. PMID: 21196321 Ref: New bichalcone analogs as NF-kappaB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis. PMID: 21377368 Ref: Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells. PMID: 21406062 Ref: Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action. PMID: 21406194 Ref: Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo. PMID: 21409599 Ref: Cytotoxic and NF-kappaB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues. PMID: 21428375 Ref: Gallotannin inhibits NFkB signaling and growth of human colon cancer xenografts. PMID: 21532339 Ref: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-kappaB signaling in the intestine. PMID: 21540105 Ref: 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. PMID: 21544861 Ref: c-Src dependency of NSAID-induced effects on NF-kappaB-mediated apoptosis in colorectal cancer cells. PMID: 21551129 Ref: Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa. PMID: 21625488 Ref: Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620. PMID: 21625939 Ref: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3. PMID: 21722370 Ref: Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer. PMID: 21771876 Ref: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. PMID: 21864401 Ref: C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFkappaB in colon cancer cells and xenograft tumors. PMID: 21900746 Ref: 3'-Chloro-5,7-dimethoxyisoflavone inhibits TNFalpha-induced CXCL10 gene transcription by suppressing the NF-kappaB pathway in HCT116 human colon cancer cells. PMID: 21945666 Ref: Epigenetic alteration of PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFalpha-induced apoptosis. PMID: 21980136 Ref: Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer. PMID: 22180364 Ref: [Role of NF-kappaB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells]. PMID: 22340043 Ref: Expression of NF-kappaB p65 phosphorylated at serine-536 in rectal cancer with or without preoperative radiotherapy. PMID: 22933966 |
Ref: Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells. PMID: 21678498 Ref: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. PMID: 21919080 Ref: Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. PMID: 22101170 Ref: NF-kappaB p65 phosphorylated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients. PMID: 22102084 Ref: Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model. PMID: 22221675 Ref: NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBalpha pathway. PMID: 22327383 Ref: Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer. PMID: 22334590 Ref: Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway. PMID: 22461522 Ref: N-alpha-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression. PMID: 22496479 Ref: Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines. PMID: 22509253 Ref: HIV-1 viral protein R (Vpr) induction of apoptosis and cell cycle arrest in multidrug-resistant colorectal cancer cells. PMID: 22552851 Ref: Cytotoxic and NF-kappaB inhibitory sesquiterpene lactones from Piptocoma rufescens. PMID: 22685350 Ref: [The expression and clinical significance of SphK1 and nuclear factor-kappaB p65 in human colon carcinoma]. PMID: 22781898 Ref: beta-Catenin and peroxisome proliferator-activated receptor-delta coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells. PMID: 23086933 Ref: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. PMID: 23110215 Ref: Effect of NF-kappaB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29. PMID: 23170132 Ref: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. PMID: 23194063 Ref: A TLR4-interacting peptide inhibits lipopolysaccharide-stimulated inflammatory responses, migration and invasion of colon cancer SW480 cells. PMID: 23264896 |
Ref: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling. PMID: 22086675 Ref: Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression. PMID: 22778026 Ref: O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms. PMID: 22965195 Ref: PRL-3 activates NF-kappaB signaling pathway by interacting with RAP1. PMID: 23178297 Ref: Chemopreventive properties of raisins originating from Greece in colon cancer cells. PMID: 23211994 Ref: Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. PMID: 23273993 Ref: A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats. PMID: 23291777 Ref: Bioactive flavaglines and other constituents isolated from Aglaia perviridis. PMID: 23301897 Ref: Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells. PMID: 23348408 Ref: Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole andrographolide derivatives. PMID: 23472133 Ref: PI3K is required for the physical interaction and functional inhibition of NF-kappaB by beta-catenin in colorectal cancer cells. PMID: 23583404 Ref: Patchouli alcohol, an essential oil of Pogostemon cablin, exhibits anti-tumorigenic activity in human colorectal cancer cells. PMID: 23602914 Ref: Epigenetic control of NF-kappaB-dependent FAS gene transcription during progression of myelodysplastic syndromes. PMID: 23604035 Ref: [CaMKIIgamma promotes in vitro and in vivo growth of colorectal cancer cells by upregulating nuclear factor-kappaB signaling pathway]. PMID: 23688981 Ref: A mechanistic study of the proapoptotic effect of tolfenamic acid: involvement of NF-kappaB activation. PMID: 23784084 Ref: Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells. PMID: 23896517 Ref: Expression of NF-kB and COX2 in colorectal cancer among native Indonesians: the role of inflammation in colorectal carcinogenesis. PMID: 24045388 Ref: Dietary black raspberries modulate DNA methylation in dextran sodium sulfate (DSS)-induced ulcerative colitis. PMID: 24067901 Ref: Sulindac activates NF-kappaB signaling in colon cancer cells. PMID: 24083678 Ref: ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-kappaB pathway. PMID: 24335275 Ref: Fermented Pu-erh tea increases in vitro anticancer activities in HT-29 cells and has antiangiogenetic effects on HUVECs. PMID: 24579782 Ref: Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo. PMID: 25621077 |
Ref: Interaction of omega-3 polyunsaturated fatty acids with radiation therapy in two different colorectal cancer cell lines. PMID: 23672803 Ref: Phenolic profiles and antioxidant and anticarcinogenic activities of Greek herbal infusions; balancing delight and chemoprevention? PMID: 24001836 Ref: Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NFkappaB. PMID: 24173769 Ref: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. PMID: 24232001 Ref: CHIP/Stub1 functions as a tumor suppressor and represses NF-kappaB-mediated signaling in colorectal cancer. PMID: 24302614 Ref: Apoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway. PMID: 24338805 Ref: Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling. PMID: 24360977 Ref: Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. PMID: 24518414 Ref: Prognostic value of c-FLIPL/s, HIF-1alpha, and NF-kappabeta in stage II and III rectal cancer. PMID: 24711168 Ref: ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. PMID: 24766737 Ref: Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer. PMID: 24828543 Ref: A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFkappaB and STAT3 in colorectal cancer cells. PMID: 24931456 Ref: Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark. PMID: 24962785 Ref: Identification of aspirin analogues that repress NF-kappaB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo. PMID: 25109257 Ref: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells. PMID: 25122478 Ref: Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs. PMID: 25134433 Ref: Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells. PMID: 25412312 Ref: Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines. PMID: 25431425 Ref: The TLR4/NF-kappaB signaling pathway mediates the growth of colon cancer. PMID: 25555874 Ref: Bioactive indole alkaloids isolated from Alstonia angustifolia. PMID: 25584095 |
Ref: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. PMID: 24497447 Ref: Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice. PMID: 24838344 Ref: Ubiquitin D is an independent prognostic marker for survival in stage IIB-IIC colon cancer patients treated with 5-fluoruracil-based adjuvant chemotherapy. PMID: 25238407 Ref: LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo. PMID: 25524577 Ref: Tolfenamic Acid Suppresses Inflammatory Stimuli-Mediated Activation of NF-kappaB Signaling. PMID: 25593642 Ref: Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFkappaB signaling. PMID: 25704885 Ref: Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors. PMID: 25825916 Ref: Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells. PMID: 25889965 Ref: Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-kappaB signaling. PMID: 25915426 Ref: Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IkappaB. PMID: 25978030 Ref: Atonal homolog 1 protein stabilized by tumor necrosis factor alpha induces high malignant potential in colon cancer cell line. PMID: 26017781 Ref: Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity. PMID: 26124005 Ref: New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis. PMID: 26132853 Ref: Parthenolide induces apoptosis in colitis-associated colon cancer, inhibiting NF-kappaB signaling. PMID: 26137027 Ref: Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-kappaB Pathway. PMID: 26202947 Ref: p53 controls colorectal cancer cell invasion by inhibiting the NF-kappaB-mediated activation of Fascin. PMID: 26362504 Ref: Chemosensitization by diverging modulation by short-term and long-term TNF-alpha action on ABCB1 expression and NF-kappaB signaling in colon cancer. PMID: 26463665 Ref: The NF-kappaB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription. PMID: 26497740 Ref: Identification of a novel compound (beta-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: comparison with curcumin. PMID: 26521943 Ref: Mulberry fruit prevents LPS-induced NF-kappaB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. PMID: 26615818 Ref: Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors. PMID: 26673922 Ref: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells. PMID: 26753095 |
Ref: Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression. PMID: 25915847 Ref: A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation. PMID: 26375985 Ref: Evodiamine Suppresses ABCG2 Mediated Drug Resistance by Inhibiting p50/p65 NF-kappaB Pathway in Colorectal Cancer. PMID: 26590365 Ref: L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPARgamma signaling. PMID: 26647854 Ref: Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-kappaB signal pathway. PMID: 26847533 Ref: Differential effect of psoralidin in enhancing apoptosis of colon cancer cells via nuclear factor-kappaB and B-cell lymphoma-2/B-cell lymphoma-2-associated X protein signaling pathways. PMID: 26870201 Ref: Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-beta-catenin axis. PMID: 26910375 Ref: DDA1 promotes stage IIB-IIC colon cancer progression by activating NFkappaB/CSN2/GSK-3beta signaling. PMID: 26942699 Ref: NF-kappaB/p65 expression before and after treatment in rectal cancer patients undergoing neoadjuvant (chemo)radiotherapy and surgery: prognostic marker for disease progression and survival. PMID: 26952512 Ref: Tanshinone IIA enhances chemosensitivity of colon cancer cells by suppressing nuclear factor-kappaB. PMID: 26998041 Ref: Overexpression of Livin promotes migration and invasion of colorectal cancer cells by induction of epithelial-mesenchymal transition via NF-kappaB activation. PMID: 27013894 Ref: GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-kappaB Pathway. PMID: 27057094 Ref: NFkappaB-Associated Pathways in Progression of Chemoresistance to 5-Fluorouracil in an In Vitro Model of Colonic Carcinoma. PMID: 27069140 Ref: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression. PMID: 27098148 Ref: Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells. PMID: 27099440 Ref: Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer. PMID: 27144516 Ref: STC1 and NF-kappaB p65 (Rel A) is Constitutively Activated in Colorectal Cancer. PMID: 27156337 Ref: Identification and verification of PRDX1 as an inflammation marker for colorectal cancer progression. PMID: 27158373 Ref: IL-1beta/NF-kb signaling promotes colorectal cancer cell growth through miR-181a/PTEN axis. PMID: 27264420 Ref: 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-kappaB activation. PMID: 27278328 Ref: Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco-2 Cells Through Regulating Toll-like Receptor 4/Nuclear Factor-kappa B Pathway. PMID: 27279714 Ref: Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/beta-catenin signaling. PMID: 27302922 Ref: Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis. PMID: 27322737 Ref: Knockdown of NDRG1 promote epithelial-mesenchymal transition of colorectal cancer via NF-kappaB signaling. PMID: 27338835 Ref: Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development. PMID: 27353028 Ref: Oxymatrine inhibits epithelial-mesenchymal transition through regulation of NF-kappaB signaling in colorectal cancer cells. PMID: 27430890 Ref: Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer. PMID: 27472952 Ref: Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1. PMID: 27529686 Ref: Rab27A mediated by NF-kappaB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion. PMID: 27556511 Ref: gamma-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. PMID: 27575851 Ref: Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation. PMID: 27613835 Ref: Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer. PMID: 27622014 Ref: Vam3, a Compound Derived from Vitis amurensis Rupr., Attenuated Colitis-Related Tumorigenesis by Inhibiting NF-kappaB Signaling Pathway. PMID: 27679575 Ref: Novel Synthetic Oxazines Target NF-kappaB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo. PMID: 27685808 Ref: Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-kappaB. PMID: 27698868 Ref: Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model. PMID: 27729020 Ref: microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells. PMID: 27769860 Ref: The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-kappaB signaling pathway. PMID: 27869910 Ref: Lipopolysaccharide-induced alpha-catenin downregulation enhances the motility of human colorectal cancer cells in an NF-kappaB signaling-dependent manner. PMID: 28008274 Ref: Protein Markers Associated with an ALDH Sub-Population in Colorectal Cancer. PMID: 28503055 |
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