Primary Site >> Colorectal Cancer

Gene >> REG4

Journal: World J Gastroenterol. 2003 Dec;9(12):2635-41.
Title: Reg gene family and human diseases.
Author: Zhang, Yu-Wei|Ding, Liu-Song|Lai, Mao-De
PMID: 14669303
Journal: Cancer Lett. 2003 Oct 8;200(1):69-76.
Title: Overexpression of Reg IV in colorectal adenoma.
Author: Zhang, Yuwei|Lai, Maode|Lv, Bingjian|Gu, Xuemei|Wang, Huiping|Zhu, Yimin|Zhu, Yangli|Shao, Lina|Wang, Guofeng
PMID: 14550954
Journal: J Pathol. 2005 Oct;207(2):185-98.
Title: Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma.
Author: Oue, Naohide|Mitani, Yoshitsugu|Aung, Phyu Phyu|Sakakura, Chouhei|Takeshima, Yukio|Kaneko, Mayumi|Noguchi, Tsuyoshi|Nakayama, Hirofumi|Yasui, Wataru
PMID: 16086444
Journal: Int J Oncol. 2006 Feb;28(2):411-20.
Title: Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel.
Author: Yeh, Ching-Sheng|Wang, Jaw-Yuan|Wu, Chan-Han|Chong, Inn-Wen|Chung, Fu-Yen|Wang, Yung-Hsin|Yu, Ya-Ping|Lin, Shiu-Ru
PMID: 16391796
Journal: Gastroenterology. 2006 Jan;130(1):137-49.
Title: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
Author: Bishnupuri, Kumar S|Luo, Qizhi|Murmu, Nabendu|Houchen, Courtney W|Anant, Shrikant|Dieckgraefe, Brian K
PMID: 16401477
Journal: Clin Chim Acta. 2007 Mar;378(1-2):42-7. Epub 2006 Nov 14.
Title: Systemic analysis of the differential gene expression profile in a colonic adenoma-normal SSH library.
Author: Lu, Bingjian|Xu, Jing|Zhu, Yiming|Zhang, Hao|Lai, Maode
PMID: 17184759
Journal: Oncology. 2007;72(5-6):371-80.
Title: Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis.
Author: Oue, Naohide|Kuniyasu, Hiroki|Noguchi, Tsuyoshi|Sentani, Kazuhiro|Ito, Masanori|Tanaka, Shinji|Setoyama, Tetsuro|Sakakura, Chouhei|Natsugoe, Shoji|Yasui, Wataru
PMID: 18187959
Journal: Mod Pathol. 2009 Mar;22(3):460-8.
Title: REG4 is associated with carcinogenesis in the 'intestinal' pathway of intraductal papillary mucinous neoplasms.
Author: Nakata, Kohei|Nagai, Eishi|Ohuchida, Kenoki|Aishima, Shinich|Hayashi, Akifumi|Miyasaka, Yoshihiro|Yu, Jun|Mizumoto, Kazuhiro|Tanaka, Masao|Tsuneyoshi, Masazumi
PMID: 19136934
Journal: Hum Pathol. 2010 Jan;41(1):59-69.
Title: The role of Reg IV gene and its encoding product in gastric carcinogenesis.
Author: Zheng, Hua-Chuan|Xu, Xiao-Yan|Yu, Miao|Takahashi, Hiroyuki|Masuda, Shinji|Takano, Yasuo
PMID: 19740514
Journal: Int J Oncol. 2010 Mar;36(3):689-98.
Title: REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells.
Author: Rafa, Louisa|Dessein, Anne-Frederique|Devisme, Louise|Buob, David|Truant, Stephanie|Porchet, Nicole|Huet, Guillemette|Buisine, Marie-Pierre|Lesuffleur, Thecla
PMID: 20126989
Journal: Int J Biol Macromol. 2011 Apr 1;48(3):511-7.
Title: Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.
Author: Li, You-Gui|Ji, Dong-Feng|Zhong, Shi|Zhu, Jian-Xun|Chen, Shi|Hu, Gui-Yan
PMID: 21262260
Journal: Anticancer Res. 2011 Dec;31(12):4147-53.
Title: REG4, NEIL2, and BIRC5 gene expression correlates with gamma-radiation sensitivity in patients with rectal cancer receiving radiotherapy.
Author: Kobunai, Takashi|Watanabe, Toshiaki|Fukusato, Toshio
PMID: 22199273
Journal: World J Gastroenterol. 2012 Jul 21;18(27):3502-10.
Title: Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers.
Author: Numata, Masakatsu|Oshima, Takashi
PMID: 22826614
Journal: PLoS One. 2012;7(11):e47545.
Title: Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.
Author: Naito, Yutaka|Oue, Naohide|Hinoi, Takao|Sakamoto, Naoya|Sentani, Kazuhiro|Ohdan, Hideki|Yanagihara, Kazuyoshi|Sasaki, Hiroki|Yasui, Wataru
PMID: 23133598
Journal: Int J Cancer. 2013 Nov 15;133(10):2325-33.
Title: Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome.
Author: Lu, Shun|Bevier, Melanie|Huhn, Stefanie|Sainz, Juan|Lascorz, Jesus|Pardini, Barbara|Naccarati, Alessio|Vodickova, Ludmila|Novotny, Jan|Hemminki, Kari|Vodicka, Pavel|Forsti, Asta
PMID: 23650115
Journal: Oncol Rep. 2013 Dec;30(6):2609-16.
Title: New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers.
Author: Sawada, Tetsuji|Yashiro, Masakazu|Sentani, Kazuhiro|Oue, Naohide|Yasui, Wataru|Miyazaki, Kohji|Kai, Keita|Fujita, Hideto|Nakamura, Keishi|Maeda, Kiyoshi|Kakeji, Yoshihiro|Natsugoe, Shoji|Shirabe, Ken|Nomura, Sachiyo|Shimada, Yutaka|Tomita, Naohiro|Hirakaw
PMID: 24101199
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E169-80.
Title: Reg4-induced mitogenesis involves Akt-GSK3beta-beta-Catenin-TCF-4 signaling in human colorectal cancer.
Author: Bishnupuri, Kumar S|Sainathan, Satheesh K|Bishnupuri, Kislay|Leahy, Devon R|Luo, Qizhi|Anant, Shrikant|Houchen, Courtney W|Dieckgraefe, Brian K
PMID: 24151146
Journal: PLoS One. 2014 Feb 12;9(2):e88367.
Title: RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers.
Author: Delker, Don A|McGettigan, Brett M|Kanth, Priyanka|Pop, Stelian|Neklason, Deborah W|Bronner, Mary P|Burt, Randall W|Hagedorn, Curt H
PMID: 24533081
Journal: J Surg Oncol. 2014 Dec;110(8):1002-10.
Title: Overexpression of REG4 confers an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy.
Author: He, Hong-Lin|Lee, Ying-En|Shiue, Yow-Ling|Lee, Sung-Wei|Lin, Li-Ching|Chen, Tzu-Ju|Wu, Ting-Feng|Hsing, Chung-Hsi|Huang, Hsuan-Ying|Wang, Jaw-Yuan|Li, Chien-Feng
PMID: 25155043
Journal: PLoS One. 2014 Oct 8;9(10):e109600.
Title: REG4 independently predicts better prognosis in non-mucinous colorectal cancer.
Author: Kaprio, Tuomas|Hagstrom, Jaana|Mustonen, Harri|Koskensalo, Selja|Andersson, Leif C|Haglund, Caj
PMID: 25295732
Journal: Oncol Rep. 2015 Jan;33(1):320-8.
Title: Overexpression of Reg4, alone or combined with MMP-7 overexpression, is predictive of poor prognosis in colorectal cancer.
Author: Zhu, Xingwu|Han, Yang|Yuan, Chenwei|Tu, Weiwei|Qiu, Guoqiang|Lu, Su|Lu, Huijun|Peng, Zhihai|Zhou, Chongzhi
PMID: 25338725
Journal: BMC Cancer. 2015 Jun 16;15:471.
Title: The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma.
Author: Chen, Shuo|Gou, Wen-Feng|Zhao, Shuang|Niu, Zhe-Feng|Zhao, Yang|Takano, Yasuo|Zheng, Hua-Chuan
PMID: 26077911
Journal: Sci Rep. 2015 Sep 21;5:14291.
Title: REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis.
Author: Kawasaki, Yoshihiro|Matsumura, Kosuke|Miyamoto, Masaya|Tsuji, Shinnosuke|Okuno, Masumi|Suda, Sakiko|Hiyoshi, Masaya|Kitayama, Joji|Akiyama, Tetsu
PMID: 26387746
Journal: Contemp Oncol (Pozn). 2015;19(4):261-4.
Title: The role of Reg IV in colorectal cancer, as a potential therapeutic target.
Author: Hu, Yiwang|Pan, Chi|Hu, Jiyi|Zhang, Suzhan
PMID: 26557771