Primary Site >> Colorectal Cancer
Gene >> REG4
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Ref: Overexpression of Reg IV in colorectal adenoma. PMID: 14550954 Ref: Reg gene family and human diseases. PMID: 14669303 |
Ref: Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. PMID: 16086444 |
Ref: Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel. PMID: 16391796 Ref: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. PMID: 16401477 |
Ref: Systemic analysis of the differential gene expression profile in a colonic adenoma-normal SSH library. PMID: 17184759 Ref: Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis. PMID: 18187959 |
Ref: REG4 is associated with carcinogenesis in the 'intestinal' pathway of intraductal papillary mucinous neoplasms. PMID: 19136934 |
Ref: The role of Reg IV gene and its encoding product in gastric carcinogenesis. PMID: 19740514 Ref: REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells. PMID: 20126989 |
Ref: Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma. PMID: 21262260 Ref: REG4, NEIL2, and BIRC5 gene expression correlates with gamma-radiation sensitivity in patients with rectal cancer receiving radiotherapy. PMID: 22199273 |
Ref: Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers. PMID: 22826614 Ref: Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer. PMID: 23133598 |
Ref: Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome. PMID: 23650115 Ref: New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers. PMID: 24101199 |
Ref: Reg4-induced mitogenesis involves Akt-GSK3beta-beta-Catenin-TCF-4 signaling in human colorectal cancer. PMID: 24151146 Ref: RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers. PMID: 24533081 Ref: Overexpression of REG4 confers an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy. PMID: 25155043 Ref: REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PMID: 25295732 |
Ref: Overexpression of Reg4, alone or combined with MMP-7 overexpression, is predictive of poor prognosis in colorectal cancer. PMID: 25338725 Ref: The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma. PMID: 26077911 Ref: REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis. PMID: 26387746 Ref: The role of Reg IV in colorectal cancer, as a potential therapeutic target. PMID: 26557771 |