Literatures

Primary Site >> Colorectal Cancer

Gene >> RASSF1

1.
Journal:	Int J Cancer. 2001 Oct 15;94(2):212-7.
Title:	Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas.
Author:	Yoon, J H\|Dammann, R\|Pfeifer, G P
PMID:	11668500

2.
Journal:	Curr Opin Oncol. 2002 Mar;14(2):171-9.
Title:	Translational oncogenomics: toward rational therapeutic decision-making.
Author:	Rosell, Rafael\|Monzo, Mariano\|O'Brate, Aurora\|Taron, Miquel
PMID:	11880707

3.
Journal:	Oncogene. 2002 May 23;21(23):3792-5.
Title:	K-ras mutations and RASSF1A promoter methylation in colorectal cancer.
Author:	van Engeland, Manon\|Roemen, Guido M J M\|Brink, Mirian\|Pachen, Marco M M\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Arends, Jan-Willem\|van den Brandt, Piet A\|de Goeij, Anton F P M\|Herman, James G
PMID:	12032847

4.
Journal:	Oncogene. 2002 Oct 17;21(47):7277-82.
Title:	Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer.
Author:	Wagner, Kate J\|Cooper, Wendy N\|Grundy, Richard G\|Caldwell, Germaine\|Jones, Carolyn\|Wadey, Roy B\|Morton, Dion\|Schofield, Paul N\|Reik, Wolf\|Latif, Farida\|Maher, Eamonn R
PMID:	12370819

5.
Journal:	Cancer Res. 2003 Mar 1;63(5):1054-8.
Title:	SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells.
Author:	Dallol, Ashraf\|Morton, Dion\|Maher, Eamonn R\|Latif, Farida
PMID:	12615722

6.
Journal:	Cancer Res. 2003 Jun 15;63(12):3133-7.
Title:	Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Author:	van Engeland, Manon\|Weijenberg, Matty P\|Roemen, Guido M J M\|Brink, Mirian\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van den Brandt, Piet A\|Baylin, Stephen B\|de Goeij, Anton F P M\|Herman, James G
PMID:	12810640

7.
Journal:	World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title:	Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author:	Xu, Xiao-Li\|Yu, Jian\|Zhang, Hong-Yu\|Sun, Meng-Hong\|Gu, Jun\|Du, Xiang\|Shi, Da-Ren\|Wang, Peng\|Yang, Zhen-Hua\|Zhu, Jing-De
PMID:	15526363

8.
Journal:	Oncogene. 2004 Nov 25;23(55):8900-7.
Title:	Frequent hypermethylation of RASSF1A in early flat-type colorectal tumors.
Author:	Sakamoto, Naoto\|Terai, Takeshi\|Ajioka, Yoichi\|Abe, Satoshi\|Kobayasi, Osamu\|Hirai, Shu\|Hino, Okio\|Watanabe, Hidenobu\|Sato, Nobuhiro\|Shimoda, Tadakazu\|Fujii, Hiroaki
PMID:	15480433

9.
Journal:	Lab Invest. 2004 Jul;84(7):884-93.
Title:	Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.
Author:	Lee, Sun\|Hwang, Kyu Sang\|Lee, Hyeon Joo\|Kim, Jung-Sun\|Kang, Gyeong Hoon
PMID:	15122305

10.
Journal:	J Biol Chem. 2004 Jul 9;279(28):29247-54. Epub 2004 Apr 9.
Title:	The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
Author:	Rabizadeh, Shahrooz\|Xavier, Ramnik J\|Ishiguro, Kazuhiro\|Bernabeortiz, Juliocesar\|Lopez-Ilasaca, Marco\|Khokhlatchev, Andrei\|Mollahan, Pamela\|Pfeifer, Gerd P\|Avruch, Joseph\|Seed, Brian
PMID:	15075335

11.
Journal:	Mod Pathol. 2005 Feb;18(2):170-8.
Title:	Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author:	Dong, Seung M\|Lee, Eui J\|Jeon, Eun S\|Park, Cheol K\|Kim, Kyoung-Mee
PMID:	15389252

12.
Journal:	Carcinogenesis. 2005 Jun;26(6):1152-6. Epub 2005 Mar 10.
Title:	CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.
Author:	Brandes, Johann C\|van Engeland, Manon\|Wouters, Kim A D\|Weijenberg, Matty P\|Herman, James G
PMID:	15760919

13.
Journal:	Oncogene. 2005 Jun 2;24(24):3987-94.
Title:	CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations.
Author:	Hesson, Luke B\|Wilson, Robin\|Morton, Dion\|Adams, Clare\|Walker, Mike\|Maher, Eamonn R\|Latif, Farida
PMID:	15806169

14.
Journal:	Oncogene. 2005 Nov 17;24(51):7630-4.
Title:	Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
Author:	Oliveira, Carla\|Velho, Sergia\|Domingo, Enric\|Preto, Ana\|Hofstra, Robert M W\|Hamelin, Richard\|Yamamoto, Hiroyuki\|Seruca, Raquel\|Schwartz, Simo Jr
PMID:	16007118

15.
Journal:	Gastroenterology. 2005 Jul;129(1):156-69.
Title:	The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.
Author:	Akino, Kimishige\|Toyota, Minoru\|Suzuki, Hiromu\|Mita, Hiroaki\|Sasaki, Yasushi\|Ohe-Toyota, Mutsumi\|Issa, Jean-Pierre J\|Hinoda, Yuji\|Imai, Kohzoh\|Tokino, Takashi
PMID:	16012945

16.
Journal:	Ann N Y Acad Sci. 2006 Sep;1075:197-203.
Title:	Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients.
Author:	Taback, Bret\|Saha, Sukamal\|Hoon, Dave S B
PMID:	17108212

17.
Journal:	Cell Oncol. 2006;28(5-6):247-57.
Title:	Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Author:	Derks, Sarah\|Postma, Cindy\|Moerkerk, Peter T M\|van den Bosch, Sandra M\|Carvalho, Beatriz\|Hermsen, Mario A J A\|Giaretti, Walter\|Herman, James G\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Meijer, Gerrit A\|van Engeland, Manon
PMID:	17167178

18.
Journal:	Br J Cancer. 2006 Oct 23;95(8):1101-7.
Title:	Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.
Author:	Miranda, E\|Destro, A\|Malesci, A\|Balladore, E\|Bianchi, P\|Baryshnikova, E\|Franchi, G\|Morenghi, E\|Laghi, L\|Gennari, L\|Roncalli, M
PMID:	16969349

19.
Journal:	J Exp Clin Cancer Res. 2006 Jun;25(2):235-42.
Title:	Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers.
Author:	Noda, H\|Kato, Y\|Yoshikawa, H\|Arai, M\|Togashi, K\|Nagai, H\|Konishi, F\|Miki, Y
PMID:	16918136

20.
Journal:	Carcinogenesis. 2006 Jul;27(7):1316-22.
Title:	Epigenetic alterations in RASSF1A in human aberrant crypt foci.
Author:	Greenspan, Emily J\|Jablonski, Melissa A\|Rajan, Thiruchandurai V\|Levine, Joel\|Belinsky, Glenn S\|Rosenberg, Daniel W
PMID:	16513682

21.
Journal:	J Invest Dermatol. 2006 Feb;126(2):422-31.
Title:	Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma.
Author:	Marini, Alessandra\|Mirmohammadsadegh, Alireza\|Nambiar, Sandeep\|Gustrau, Annett\|Ruzicka, Thomas\|Hengge, Ulrich R
PMID:	16374457

22.
Journal:	Cancer Lett. 2006 Jul 8;238(1):128-34. Epub 2005 Aug 25.
Title:	Single nucleotide polymorphism at codon 133 of the RASSF1 gene is preferentially associated with human lung adenocarcinoma risk.
Author:	Kanzaki, Hirotaka\|Hanafusa, Hiroko\|Yamamoto, Hiromasa\|Yasuda, Yukiko\|Imai, Kazue\|Yano, Masaaki\|Aoe, Motoi\|Shimizu, Nobuyoshi\|Nakachi, Kei\|Ouchida, Mamoru\|Shimizu, Kenji
PMID:	16125301

23.
Journal:	Genome Res. 2006 Feb;16(2):282-9.
Title:	Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Author:	Cheng, Yu-Wei\|Shawber, Carrie\|Notterman, Dan\|Paty, Philip\|Barany, Francis
PMID:	16369045

24.
Journal:	J Mol Diagn. 2006 May;8(2):193-201.
Title:	Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas.
Author:	Sugai, Tamotsu\|Habano, Wataru\|Jiao, Yu-Fei\|Tsukahara, Mitsunori\|Takeda, Yuichiro\|Otsuka, Koki\|Nakamura, Shin-ichi
PMID:	16645205

25.
Journal:	Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6.
Title:	Promoter methylation status of multiple genes in uveal melanoma.
Author:	Merhavi, Efrat\|Cohen, Yoram\|Avraham, Bat Chen R\|Frenkel, Shahar\|Chowers, Itay\|Pe'er, Jacob\|Goldenberg-Cohen, Nitza
PMID:	17898258

26.
Journal:	J Exp Clin Cancer Res. 2007 Dec;26(4):521-6.
Title:	Promoter hypermethylation of tumor-related genes in sporadic colorectal cancer in young patients.
Author:	Noda, H\|Mashima, R\|Kamiyama, H\|Okada, S\|Kawamura, Y J\|Konishi, F
PMID:	18365548

27.
Journal:	Carcinogenesis. 2008 Feb;29(2):434-9.
Title:	Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Author:	Derks, Sarah\|Postma, Cindy\|Carvalho, Beatriz\|van den Bosch, Sandra M\|Moerkerk, Peter T M\|Herman, James G\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Meijer, Gerrit A\|van Engeland, Manon
PMID:	18048385

28.
Journal:	World J Gastroenterol. 2008 May 21;14(19):3074-80.
Title:	Detection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients.
Author:	Wang, Yu-Cai\|Yu, Zheng-Hong\|Liu, Chang\|Xu, Li-Zhi\|Yu, Wen\|Lu, Jia\|Zhu, Ren-Min\|Li, Guo-Li\|Xia, Xin-Yi\|Wei, Xiao-Wei\|Ji, Hong-Zan\|Lu, Heng\|Gao, Yong\|Gao, Wei-Min\|Chen, Long-Bang
PMID:	18494062

29.
Journal:	Cancer Res. 2008 Jun 15;68(12):4597-605.
Title:	Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Author:	Joensuu, Emmi I\|Abdel-Rahman, Wael M\|Ollikainen, Miina\|Ruosaari, Salla\|Knuutila, Sakari\|Peltomaki, Paivi
PMID:	18559504

30.
Journal:	Neoplasia. 2008 Jul;10(7):680-6, 2 p following 686.
Title:	RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A.
Author:	Ahlquist, Terje\|Bottillo, Irene\|Danielsen, Stine A\|Meling, Gunn I\|Rognum, Torleiv O\|Lind, Guro E\|Dallapiccola, Bruno\|Lothe, Ragnhild A
PMID:	18592002

31.
Journal:	Int J Biol Markers. 2009 Jan-Mar;24(1):57-62.
Title:	Gene-specific methylation: potential markers for colorectal cancer.
Author:	Prabhu, Jyothi S\|Korlimarla, Aruna\|Banerjee, Arindam\|Wani, Shivangi\|K, Payal\|Sahoo, Rashmita
PMID:	19404924

32.
Journal:	PLoS One. 2010 Jan 19;5(1):e8777.
Title:	Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.
Author:	Gonzalo, Victoria\|Lozano, Juan Jose\|Munoz, Jenifer\|Balaguer, Francesc\|Pellise, Maria\|Rodriguez de Miguel, Cristina\|Andreu, Montserrat\|Jover, Rodrigo\|Llor, Xavier\|Giraldez, M Dolores\|Ocana, Teresa\|Serradesanferm, Anna\|Alonso-Espinaco, Virginia\|Jimeno, Mire
PMID:	20098741

33.
Journal:	Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1184-92.
Title:	A gene expression signature for chemoradiosensitivity of colorectal cancer cells.
Author:	Spitzner, Melanie\|Emons, Georg\|Kramer, Frank\|Gaedcke, Jochen\|Rave-Frank, Margret\|Scharf, Jens-Gerd\|Burfeind, Peter\|Becker, Heinz\|Beissbarth, Tim\|Ghadimi, B Michael\|Ried, Thomas\|Grade, Marian
PMID:	20970032

34.
Journal:	Tumour Biol. 2010 Oct;31(5):503-11.
Title:	Hypermethylation of RARbeta2 correlates with high COX-2 expression and poor prognosis in patients with colorectal carcinoma.
Author:	Miladi-Abdennadher, Imen\|Abdelmaksoud-Damak, Rania\|Ayadi, Lobna\|Khabir, Abdelmajid\|Frikha, Foued\|Kallel, Lamia\|Amouri, Ali\|Frikha, Mounir\|Sellami-Boudawara, Tahia\|Gargouri, Ali\|Mokdad-Gargouri, Raja
PMID:	20571967

35.
Journal:	Int J Cancer. 2010 Nov 1;127(9):2095-105.
Title:	Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers.
Author:	An, Byonggu\|Kondo, Yutaka\|Okamoto, Yasuyuki\|Shinjo, Keiko\|Kanemitsu, Yukihide\|Komori, Koji\|Hirai, Takashi\|Sawaki, Akira\|Tajika, Masahiro\|Nakamura, Tsuneya\|Yamao, Kenji\|Yatabe, Yasushi\|Fujii, Makiko\|Murakami, Hideki\|Osada, Hirotaka\|Tani, Tohru\|Matsuo, Keit
PMID:	20131317

36.
Journal:	Tumour Biol. 2011 Oct;32(5):845-52.
Title:	Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors.
Author:	Abouzeid, Hamdy E\|Kassem, Abdel Meguid\|Abdel Wahab, Abdel Hady\|El-mezayen, Hatem A\|Sharad, Hayaat\|Abdel Rahman, Shaimaa
PMID:	21274674

37.
Journal:	Carcinogenesis. 2011 Jul;32(7):1033-42.
Title:	MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1.
Author:	Wang, Hui\|Wu, Jiangxue\|Meng, Xiangqi\|Ying, Xiaofang\|Zuo, Yufang\|Liu, Ranyi\|Pan, Zhizhong\|Kang, Tiebang\|Huang, Wenlin
PMID:	21565830

38.
Journal:	Int J Oncol. 2011 Sep;39(3):683-8.
Title:	Hypermethylation of promoter regions of the APC1A and p16INK4a genes in relation to prognosis and tumor characteristics in cervical cancer patients.
Author:	Lof-Ohlin, Zarah M\|Sorbe, Bengt\|Wingren, Sten\|Nilsson, Torbjorn K
PMID:	21674126

39.
Journal:	Mol Cell. 2011 Dec 23;44(6):893-906.
Title:	Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
Author:	Matallanas, David\|Romano, David\|Al-Mulla, Fahd\|O'Neill, Eric\|Al-Ali, Waleed\|Crespo, Piero\|Doyle, Brendan\|Nixon, Colin\|Sansom, Owen\|Drosten, Matthias\|Barbacid, Mariano\|Kolch, Walter
PMID:	22195963

40.
Journal:	Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2069-75.
Title:	Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer.
Author:	Dallol, Ashraf\|Al-Maghrabi, Jaudah\|Buhmeida, Abdelbaset\|Gari, Mamdooh A\|Chaudhary, Adeel G\|Schulten, Hans-Juergen\|Abuzenadah, Adel M\|Al-Ahwal, Mahmoud S\|Sibiany, Abdulrahman\|Al-Qahtani, Mohammed H
PMID:	23010642

41.
Journal:	Methods Mol Biol. 2012;863:3-14.
Title:	Epigenetic markers of early tumor development.
Author:	Dumitrescu, Ramona G
PMID:	22359284

42.
Journal:	Genet Test Mol Biomarkers. 2012 Nov;16(11):1277-81.
Title:	beta-catenin and K-ras mutations and RASSF1A promoter methylation in Taiwanese colorectal cancer patients.
Author:	Chen, Shee-Ping\|Wu, Chang-Chieh\|Huang, Sung-Ying\|Kang, Jung-Cheng\|Chiu, Sheng-Chun\|Yang, Kuo-Liang\|Pang, Cheng-Yoong
PMID:	23009572

43.
Journal:	J Prev Med Public Health. 2012 Jul;45(4):251-8.
Title:	Quantitative analysis of cancer-associated gene methylation connected to risk factors in Korean colorectal cancer patients.
Author:	Kang, Ho-Jin\|Kim, Eun-Jeong\|Kim, Byoung-Gwon\|You, Chang-Hun\|Lee, Sang-Yong\|Kim, Dong-Il\|Hong, Young-Seoub
PMID:	22880157

44.
Journal:	Cancer Res. 2012 Aug 1;72(15):3817-27.
Title:	Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis.
Author:	van der Weyden, Louise\|Papaspyropoulos, Angelos\|Poulogiannis, George\|Rust, Alistair G\|Rashid, Mamunur\|Adams, David J\|Arends, Mark J\|O'Neill, Eric
PMID:	22710434

45.
Journal:	Cancer Lett. 2012 Sep 28;322(2):204-12.
Title:	Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation.
Author:	Kikuyama, Mizuho\|Takeshima, Hideyuki\|Kinoshita, Takayuki\|Okochi-Takada, Eriko\|Wakabayashi, Mika\|Akashi-Tanaka, Sadako\|Ogawa, Toshihisa\|Seto, Yasuyuki\|Ushijima, Toshikazu
PMID:	22433712

46.
Journal:	FASEB J. 2012 Jun;26(6):2446-56.
Title:	The cellular apoptosis susceptibility CAS/CSE1L gene protects ovarian cancer cells from death by suppressing RASSF1C.
Author:	Lorenzato, Annalisa\|Martino, Cosimo\|Dani, Nadia\|Oligschlager, Yvonne\|Ferrero, Anna Maria\|Biglia, Nicoletta\|Calogero, Raffaele\|Olivero, Martina\|Di Renzo, Maria Flavia
PMID:	22389439

47.
Journal:	Int J Cancer. 2012 Sep 1;131(5):1153-7.
Title:	DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polyps.
Author:	Cassinotti, Elisa\|Melson, Joshua\|Liggett, Thomas\|Melnikov, Anatoliy\|Yi, Qilong\|Replogle, Charles\|Mobarhan, Sohrab\|Boni, Luigi\|Segato, Sergio\|Levenson, Victor
PMID:	22020530

48.
Journal:	Mol Biol (Mosk). 2012 Mar-Apr;46(2):260-8.
Title:	[Alterations of expression level of RASSFIA gene in primary epithelial tumors of various locations].
Author:	Pronina, I V\|Loginov, V I\|Kholdyrev, D S\|Kazubskaia, T P\|Braga, E A
PMID:	22670522

49.
Journal:	Epigenetics. 2013 Aug;8(8):807-15.
Title:	Toward a comprehensive and systematic methylome signature in colorectal cancers.
Author:	Ashktorab, Hassan\|Rahi, Hamed\|Wansley, Daniel\|Varma, Sudhir\|Shokrani, Babak\|Lee, Edward\|Daremipouran, Mohammad\|Laiyemo, Adeyinka\|Goel, Ajay\|Carethers, John M\|Brim, Hassan
PMID:	23975090

50.
Journal:	Biomed Res Int. 2013;2013:976765.
Title:	Loss of RASSF1A expression in colorectal cancer and its association with K-ras status.
Author:	Cao, Dan\|Chen, Ye\|Tang, Yuan\|Peng, Xing-Chen\|Dong, Hang\|Li, Long-Hao\|Cheng, Ke\|Ge, Jun\|Liu, Ji-Yan
PMID:	23865079

51.
Journal:	PLoS One. 2013;8(4):e60142.
Title:	Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
Author:	Sinha, Rupal\|Hussain, Showket\|Mehrotra, Ravi\|Kumar, R Suresh\|Kumar, Kapil\|Pande, Pankaj\|Doval, Dinesh Chandra\|Basir, Seemi Farhat\|Bharadwaj, Mausumi
PMID:	23573237

52.
Journal:	Breast Cancer Res. 2013 Jan 15;15(1):R4.
Title:	Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening.
Author:	Kloten, Vera\|Becker, Birte\|Winner, Kirsten\|Schrauder, Michael G\|Fasching, Peter A\|Anzeneder, Tobias\|Veeck, Jurgen\|Hartmann, Arndt\|Knuchel, Ruth\|Dahl, Edgar
PMID:	23320751

53.
Journal:	Int J Oncol. 2013 Jan;42(1):127-33.
Title:	DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients.
Author:	Nilsson, Torbjorn K\|Lof-Ohlin, Zarah M\|Sun, Xiao-Feng
PMID:	23128528

54.
Journal:	Cancer. 2013 Jan 15;119(2):266-76.
Title:	Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.
Author:	Miranda, Elena\|Bianchi, Paolo\|Destro, Annarita\|Morenghi, Emanuela\|Malesci, Alberto\|Santoro, Armando\|Laghi, Luigi\|Roncalli, Massimo
PMID:	22786759

55.
Journal:	Int J Cancer. 2013 Jan 15;132(2):251-8.
Title:	Colorectal cancer and RASSF family--a special emphasis on RASSF1A.
Author:	Fernandes, Maria Sofia\|Carneiro, Fatima\|Oliveira, Carla\|Seruca, Raquel
PMID:	22733432

56.
Journal:	Epigenetics. 2014 Apr;9(4):621-33.
Title:	Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
Author:	Coppede, Fabio\|Migheli, Francesca\|Lopomo, Angela\|Failli, Alessandra\|Legitimo, Annalisa\|Consolini, Rita\|Fontanini, Gabriella\|Sensi, Elisa\|Servadio, Adele\|Seccia, Massimo\|Zocco, Giuseppe\|Chiarugi, Massimo\|Spisni, Roberto\|Migliore, Lucia
PMID:	24500500

57.
Journal:	Mol Biol Rep. 2014 Jun;41(6):3991-9.
Title:	Aberrant promoter methylation of RASSF1A gene may be correlated with colorectal carcinogenesis: a meta-analysis.
Author:	Wang, He-Ling\|Zhang, Yu\|Liu, Peng\|Zhou, Ping-Yi
PMID:	24566684

58.
Journal:	Ann Hum Genet. 2014 May;78(3):208-16.
Title:	Promoter methylation of the RASSF1A gene may contribute to colorectal cancer susceptibility: a meta-analysis of cohort studies.
Author:	Wang, He-Ling\|Liu, Peng\|Zhou, Ping-Yi\|Zhang, Yu
PMID:	24621386

59.
Journal:	Mol Carcinog. 2015 Dec;54(12):1786-95.
Title:	Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics.
Author:	Laskar, Ruhina Shirin\|Ghosh, Sankar Kumar\|Talukdar, Fazlur Rahman
PMID:	25418895

60.
Journal:	Tumour Biol. 2015 Jun;36(6):4661-70.
Title:	Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population.
Author:	Laskar, Ruhina S\|Talukdar, Fazlur R\|Choudhury, Javed H\|Singh, Seram Anil\|Kundu, Sharbadeb\|Dhar, Bishal\|Mondal, Rosy\|Ghosh, Sankar Kumar
PMID:	25647260

61.
Journal:	Epigenomics. 2015;7(2):175-86.
Title:	Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer.
Author:	Coppede, Fabio\|Grossi, Enzo\|Lopomo, Angela\|Spisni, Roberto\|Buscema, Massimo\|Migliore, Lucia
PMID:	25942531

62.
Journal:	Zhonghua Yi Xue Za Zhi. 2016 Feb;96(6):456-9.
Title:	[Methylation status of PCDH10 and RASSF1A gene promoters in colorectal cancer].
Author:	Li, M\|Yan, D G\|Liu, J L
PMID:	26875923

63.
Journal:	Oncotarget. 2016 Oct 18;7(42):67841-67850.
Title:	beta-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients.
Author:	Schirosi, Laura\|Mazzotta, Annalisa\|Opinto, Giuseppina\|Pinto, Rosamaria\|Graziano, Giusi\|Tommasi, Stefania\|Fucci, Livia\|Simone, Giovanni\|Mangia, Anita
PMID:	27765918

64.
Journal:	Oncol Lett. 2016 Jul;12(1):748-756.
Title:	Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer.
Author:	Matthaios, Dimitrios\|Balgkouranidou, Ioanna\|Karayiannakis, Anastasios\|Bolanaki, Helen\|Xenidis, Nikolaos\|Amarantidis, Kyriakos\|Chelis, Leonidas\|Romanidis, Konstantinos\|Chatzaki, Aikaterini\|Lianidou, Evi\|Trypsianis, Grigorios\|Kakolyris, Stylianos
PMID:	27347211

65.
Journal:	Oncol Lett. 2016 Jul;12(1):139-143.
Title:	Delineating the effect of demethylating agent 5-aza-2'-deoxycytidine on human Caco-2 colonic carcinoma cells.
Author:	Li, Xiumei\|Qin, Bingzhao\|Liu, B O
PMID:	27347114

66.
Journal:	Ann Hum Genet. 2016 Jul;80(4):246.
Title:	Retraction: Promoter Methylation of the RASSF1A Gene may Contribute to Colorectal Cancer Susceptibility: A Meta-Analysis of Cohort Studies.
Author:
PMID:	27346737

67.
Journal:	Colorectal Dis. 2016 Jun;18(6):549-61.
Title:	Hypermethylated DNA as a biomarker for colorectal cancer: a systematic review.
Author:	Rasmussen, S L\|Krarup, H B\|Sunesen, K G\|Pedersen, I S\|Madsen, P H\|Thorlacius-Ussing, O
PMID:	26998585

68.
Journal:	Int J Oncol. 2016 May;48(5):1977-84.
Title:	Epigenetic silencing of miR-181b contributes to tumorigenicity in colorectal cancer by targeting RASSF1A.
Author:	Zhao, Lun-De\|Zheng, Wei-Wei\|Wang, Gao-Xiang\|Kang, Xiao-Chun\|Qin, Lei\|Ji, Juan-Juan\|Hao, Sha
PMID:	26935905

69.
Journal:	Pharmacogenomics J. 2016 Aug;16(4):312-9.
Title:	Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.
Author:	Sebio, A\|Matsusaka, S\|Zhang, W\|Yang, D\|Ning, Y\|Stremitzer, S\|Stintzing, S\|Sunakawa, Y\|Yamauchi, S\|Fujimoto, Y\|Ueno, M\|Lenz, H-J
PMID:	26370619

70.
Journal:	Ann Surg Oncol. 2017 Feb;24(2):578-585.
Title:	Methylation of the Tumor Suppressor Genes HIC1 and RassF1A Clusters Independently From the Methylation of Polycomb Target Genes in Colon Cancer.
Author:	Chen, Hong-Chang\|Huang, Hsuan-Yuan\|Chen, Yao-Li\|Lee, Kuan-Der\|Chu, Yi-Ru\|Lin, Ping-Yi\|Hsu, Chia-Chen\|Chu, Pei-Yi\|Huang, Tim H-M\|Hsiao, Shu-Huei\|Leu, Yu-Wei
PMID:	26671036

71.
Journal:	Cell Mol Biol (Noisy-le-grand). 2017 Feb 28;63(2):79-87.
Title:	The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer.
Author:	Tokarz, P\|Pawlowska, E\|Bialkowska-Warzecha, J\|Blasiak, J
PMID:	28364795

72.
Journal:	Clin Epigenetics. 2017 May 18;9:55.
Title:	Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa.
Author:	Sugai, Tamotsu\|Yoshida, Masakazu\|Eizuka, Makoto\|Uesugii, Noriyuki\|Habano, Wataru\|Otsuka, Kouki\|Sasaki, Akira\|Yamamoto, Eiichiro\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	28533824

73.
Journal:	Eur Rev Med Pharmacol Sci. 2017 Jun;21(11):2611-2616.
Title:	Screening and identification of a tumor specific methylation phenotype in the colorectal laterally spreading tumor.
Author:	Ni, H-B\|Wang, F-Y\|Xu, J\|He, X-J\|Chen, J\|Wu, Q\|Wu, J-F\|Sun, Y-S
PMID:	28678324

74.
Journal:	Med Sci Monit. 2017 Nov 12;23:5389-5395.
Title:	Promoter Methylation of RASSF1A indicates Prognosis for Patients with Stage II and III Colorectal Cancer Treated with Oxaliplatin-Based Chemotherapy.
Author:	Sun, Xicai\|Yuan, Wei\|Hao, Furong\|Zhuang, Wenzhen
PMID:	29128865

75.
Journal:	Pharmacogenomics J. 2018 Jan;18(1):43-48.
Title:	A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials.
Author:	Sebio, A\|Stintzing, S\|Heinemann, V\|Sunakawa, Y\|Zhang, W\|Ichikawa, W\|Tsuji, A\|Takahashi, T\|Parek, A\|Yang, D\|Cao, S\|Ning, Y\|Stremitzer, S\|Matsusaka, S\|Okazaki, S\|Barzi, A\|Berger, M D\|Lenz, H-J
PMID:	27698403

76.
Journal:	Oncotarget. 2018 Jan 9;9(6):7010-7022.
Title:	The prognostic efficacy of cell-free DNA hypermethylation in colorectal cancer.
Author:	Rasmussen, Simon Ladefoged\|Krarup, Henrik Bygum\|Sunesen, Kare Gotschalck\|Johansen, Martin Berg\|Stender, Mogens Tornby\|Pedersen, Inge Sokilde\|Madsen, Poul Henning\|Thorlacius-Ussing, Ole
PMID:	29467946

77.
Journal:	J Transl Med. 2018 Feb 27;16(1):45.
Title:	A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.
Author:	Freitas, Micaela\|Ferreira, Fabio\|Carvalho, Sonia\|Silva, Fernanda\|Lopes, Paula\|Antunes, Luis\|Salta, Sofia\|Diniz, Francisca\|Santos, Lucio Lara\|Videira, Jose Flavio\|Henrique, Rui\|Jeronimo, Carmen
PMID:	29486770

78.
Journal:	Cell Physiol Biochem. 2018;48(3):1259-1273.
Title:	Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation.
Author:	Blanchard, Thomas G\|Lapidus, Rena\|Banerjee, Vivekjyoti\|Bafford, Andrea C\|Czinn, Steven J\|Ahmed, Hafiz\|Banerjee, Aditi
PMID:	30045022

79.
Journal:	Pathol Res Pract. 2018 Oct;214(10):1572-1578.
Title:	Diagnostic value of RASSF1A hypermethylation in colorectal cancer: a meta-analysis.
Author:	Hu, Haochang\|Zhou, Cong\|Li, Bin\|Chen, Yanfei\|Dai, Jie\|Mao, Yiyi\|Huang, Tianyi\|Yu, Hang\|Chen, Min\|Zhao, Jun\|Duan, Shiwei
PMID:	30082160

80.
Journal:	J Gastroenterol Hepatol. 2018 Sep 18.
Title:	RASSF1A suppresses colorectal tumor cell growth through p53-dependent p21(WAF1) activation.
Author:	Oh, Shin Ju\|Lee, Min-Goo\|Moon, Jung Rock\|Lee, Chang Kyun\|Chi, Sung-Gil\|Kim, Hyo Jong
PMID:	30226276

81.
Journal:	Asian Pac J Cancer Prev. 2018 Oct 29;19(10):2991-2999.
Title:	Metformin Reshapes the Methylation Profile in Breast and Colorectal Cancer Cells
Author:	Sabit, Hussein\|Abdel-Ghany, Shimaa E\|M Said, Osama A\|Mostafa, Mohamed A\|El-Zawahry, Mokhtar
PMID:	30371994