Primary Site >> Colorectal Cancer

Gene >> RASA1

Journal: Cancer Res. 1996 Jun 15;56(12):2872-6.
Title: Suppression of a human colon cancer cell line by introduction of an exogenous NF1 gene.
Author: Li, Y|White, R
PMID: 8665528
Journal: Mol Cell Biochem. 1997 Oct;175(1-2):195-204.
Title: Expression of the placenta-specific, 100 kDa ras GTPase activating protein in several human cancer cell lines and normal human tissues.
Author: Araki, Y|Nakamura, K|Chijiiwa, Y|Nawata, H
PMID: 9350052
Journal: J Pathol. 1999 Mar;187(4):433-8.
Title: Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.
Author: Al-Mulla, F|Milner-White, E J|Going, J J|Birnie, G D
PMID: 10398103
Journal: Int J Cancer. 2003 Nov 10;107(3):387-93.
Title: High frequency of activated K-ras codon 15 mutant in colorectal carcinomas from Taiwanese patients.
Author: Wang, Jaw-Yuan|Hsieh, Jan-Sing|Chen, Fang-Ming|Yeh, Ching-Sheng|Alexandersen, Ketil|Huang, Tsung-Jen|Chen, David c p|Lin, Shiu-Ru
PMID: 14506738
Journal: Carcinogenesis. 2005 Jul;26(7):1207-14.
Title: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade.
Author: Zhu, Yongliang|Zhong, Xian|Zheng, Shu|Ge, Zhen|Du, Qin|Zhang, Suzhang
PMID: 15774489
Journal: Gastroenterology. 2009 Jan;136(1):206-16.
Title: Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression.
Author: Ohta, Miki|Seto, Motoko|Ijichi, Hideaki|Miyabayashi, Koji|Kudo, Yotaro|Mohri, Dai|Asaoka, Yoshinari|Tada, Motohisa|Tanaka, Yasuo|Ikenoue, Tsuneo|Kanai, Fumihiko|Kawabe, Takao|Omata, Masao
PMID: 18992247
Journal: J Natl Cancer Inst. 2009 Jun 3;101(11):828-32.
Title: Effect of RasGAP N2 fragment-derived peptide on tumor growth in mice.
Author: Michod, David|Annibaldi, Alessandro|Schaefer, Stephan|Dapples, Christine|Rochat, Bertrand|Widmann, Christian
PMID: 19470951
Journal: Cancer Lett. 2011 Sep 1;308(1):62-70.
Title: RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-kappaB in colon carcinoma HCT116 cells.
Author: Zhang, Hao|Zhang, Shenghua|He, Hongwei|Zhao, Wuli|Ren, Kaihuan|Chen, Jianhua|Shao, Rong-guang
PMID: 21570766
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2012 Mar;32(3):306-11.
Title: [Construction of has-miR-335 lentiviral vector and verification of the target gene of miR-335].
Author: Yang, Hui|Zhang, Chao|Lu, Yan-Xia|Wu, Xiao-Jin|Yuan, Li|Zhou, Chang|Zhou, Chun-Ping|Liu, Guo-Bing|Li, Xue-Nong
PMID: 22445972
Journal: Cancer Sci. 2012 Oct;103(10):1848-56.
Title: GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells.
Author: Zhang, Hao|Zhang, Shenghua|He, Hongwei|Zhao, Wuli|Chen, Jianhua|Shao, Rong-guang
PMID: 22703643
Journal: J Biol Chem. 2013 Mar 29;288(13):9508-18.
Title: MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1).
Author: Sun, Defang|Yu, Feng|Ma, Yutao|Zhao, Ran|Chen, Xi|Zhu, Jie|Zhang, Chen-Yu|Chen, Jiangning|Zhang, Junfeng
PMID: 23322774
Journal: PLoS One. 2014 Jan 21;9(1):e86103.
Title: p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line.
Author: Organ, Shawna L|Hai, Josephine|Radulovich, Nikolina|Marshall, Christopher B|Leung, Lisa|Sasazuki, Takehiko|Shirasawa, Senji|Zhu, Chang-Qi|Navab, Roya|Ikura, Mitsuhiko|Tsao, Ming-Sound
PMID: 24465899
Journal: Acta Pharm Sin B. 2014 Apr;4(2):128-34.
Title: RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells.
Author: Zhang, Hao|Zhang, Shenghua|He, Hongwei|Zhang, Caixia|Chen, Yi|Yu, Dongke|Chen, Jianhua|Shao, Rongguang
PMID: 26579374
Journal: Apoptosis. 2014 Apr;19(4):719-33.
Title: TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak.
Author: Annibaldi, Alessandro|Heulot, Mathieu|Martinou, Jean-Claude|Widmann, Christian
PMID: 24362790
Journal: World J Gastroenterol. 2015 Feb 7;21(5):1488-97.
Title: MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways.
Author: Gong, Bo|Liu, Wan-Wei|Nie, Wen-Jing|Li, Dong-Feng|Xie, Zi-Jun|Liu, Chao|Liu, Yan-Hui|Mei, Ping|Li, Zi-Jun
PMID: 25663768
Journal: Br J Cancer. 2015 Apr 28;112(9):1491-500.
Title: C/EBP-beta-activated microRNA-223 promotes tumour growth through targeting RASA1 in human colorectal cancer.
Author: Sun, D|Wang, C|Long, S|Ma, Y|Guo, Y|Huang, Z|Chen, X|Zhang, C|Chen, J|Zhang, J
PMID: 25867276
Journal: PLoS One. 2015 May 14;10(5):e0126670.
Title: Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.
Author: Kim, Richard|Schell, Michael J|Teer, Jamie K|Greenawalt, Danielle M|Yang, Mingli|Yeatman, Timothy J
PMID: 25974029
Journal: Mol Cell Biochem. 2016 Jan;412(1-2):235-45.
Title: Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells.
Author: Lu, Yanxia|Yang, Hui|Yuan, Li|Liu, Guobing|Zhang, Chao|Hong, Min|Liu, Yan|Zhou, Min|Chen, Fang|Li, Xuenong
PMID: 26708214
Journal: J Biol Chem. 2016 Feb 26;291(9):4589-602.
Title: p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance.
Author: Antoine-Bertrand, Judith|Duquette, Philippe M|Alchini, Ricardo|Kennedy, Timothy E|Fournier, Alyson E|Lamarche-Vane, Nathalie
PMID: 26710849
Journal: Mol Cancer Res. 2016 Mar;14(3):267-77.
Title: Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1.
Author: Kent, Oliver A|Mendell, Joshua T|Rottapel, Robert
PMID: 26747707
Journal: Sci Rep. 2016 Oct 18;6:35308.
Title: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.
Author: Teng, Hao-Wei|Hung, Man-Hsin|Chen, Li-Ju|Chang, Mao-Ju|Hsieh, Feng-Shu|Tsai, Ming-Hsien|Huang, Jui-Wen|Lin, Chih-Lung|Tseng, Hsiang-Wen|Kuo, Zong-Keng|Jiang, Jeng-Kai|Yang, Shung-Haur|Shiau, Chung-Wai|Chen, Kuen-Feng
PMID: 27752061
Journal: Gastroenterology. 2017 Mar;152(4):851-866.e24.
Title: Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-kappaB, and Up-regulating Expression of MicroRNA-21.
Author: Yang, Yongzhi|Weng, Wenhao|Peng, Junjie|Hong, Leiming|Yang, Lei|Toiyama, Yuji|Gao, Renyuan|Liu, Minfeng|Yin, Mingming|Pan, Cheng|Li, Hao|Guo, Bomin|Zhu, Qingchao|Wei, Qing|Moyer, Mary-Pat|Wang, Ping|Cai, Sanjun|Goel, Ajay|Qin, Huanlong|Ma, Yanlei
PMID: 27876571
Journal: Int J Cancer. 2017 Jul 1;141(1):172-183.
Title: Down-regulation of DAB2IP promotes colorectal cancer invasion and metastasis by translocating hnRNPK into nucleus to enhance the transcription of MMP2.
Author: Zhu, X H|Wang, J M|Yang, S S|Wang, F F|Hu, J L|Xin, S N|Men, H|Lu, G F|Lan, X L|Zhang, D|Wang, X Y|Liao, W T|Ding, Y Q|Liang, L
PMID: 28335083
Journal: Sci Rep. 2017 Apr 10;7:45612.
Title: Corrigendum: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.
Author: Teng, Hao-Wei|Hung, Man-Hsin|Chen, Li-Ju|Chang, Mao-Ju|Hsieh, Feng-Shu|Tsai, Ming-Hsien|Huang, Jui-Wen|Lin, Chih-Lung|Tseng, Hsiang-Wen|Kuo, Zong-Keng|Jiang, Jeng-Kai|Yang, Shung-Haur|Shiau, Chung-Wai|Chen, Kuen-Feng
PMID: 28394314
Journal: Mol Cancer. 2018 Jul 23;17(1):102.
Title: RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.
Author: Pan, Yi|Tong, Joanna Hung Man|Lung, Raymond Wai Ming|Kang, Wei|Kwan, Johnny Sheung Him|Chak, Wing Po|Tin, Ka Yee|Chung, Lau Ying|Wu, Feng|Ng, Simon Siu Man|Mak, Tony Wing Chung|Yu, Jun|Lo, Kwok Wai|Chan, Anthony Wing Hung|To, Ka Fai
PMID: 30037330