Primary Site >> Colorectal Cancer
Gene >> RASA1
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Ref: Suppression of a human colon cancer cell line by introduction of an exogenous NF1 gene. PMID: 8665528 |
Ref: Expression of the placenta-specific, 100 kDa ras GTPase activating protein in several human cancer cell lines and normal human tissues. PMID: 9350052 |
Ref: Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression. PMID: 10398103 |
Ref: High frequency of activated K-ras codon 15 mutant in colorectal carcinomas from Taiwanese patients. PMID: 14506738 |
Ref: Transformation of immortalized colorectal crypt cells by microcystin involving constitutive activation of Akt and MAPK cascade. PMID: 15774489 |
Ref: Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression. PMID: 18992247 Ref: Effect of RasGAP N2 fragment-derived peptide on tumor growth in mice. PMID: 19470951 |
Ref: RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-kappaB in colon carcinoma HCT116 cells. PMID: 21570766 |
Ref: [Construction of has-miR-335 lentiviral vector and verification of the target gene of miR-335]. PMID: 22445972 Ref: GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells. PMID: 22703643 |
Ref: MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1). PMID: 23322774 |
Ref: TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak. PMID: 24362790 Ref: p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line. PMID: 24465899 Ref: RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells. PMID: 26579374 |
Ref: MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways. PMID: 25663768 Ref: C/EBP-beta-activated microRNA-223 promotes tumour growth through targeting RASA1 in human colorectal cancer. PMID: 25867276 Ref: Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era. PMID: 25974029 |
Ref: Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells. PMID: 26708214 Ref: p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance. PMID: 26710849 Ref: Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1. PMID: 26747707 Ref: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma. PMID: 27752061 |
Ref: Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-kappaB, and Up-regulating Expression of MicroRNA-21. PMID: 27876571 Ref: Down-regulation of DAB2IP promotes colorectal cancer invasion and metastasis by translocating hnRNPK into nucleus to enhance the transcription of MMP2. PMID: 28335083 Ref: Corrigendum: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma. PMID: 28394314 |
Ref: RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer. PMID: 30037330 |